| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lele Shi, Huabin Cao, Junrong Luo, Ping Liu, Tiancheng Wang, Guoliang Hu, Caiying Zhan. Effects of molybdenum and cadmium on the oxidative damage and kidney apoptosis in Duck. Ecotoxicology and environmental safety. vol 145. 2017-12-01. PMID:28692912. |
taken together, it was suggested that dietary mo and cd might lead to oxidative stress, kidney apoptosis and disturb homeostasis of trace elements in duck, and it showed a possible synergistic relationship between the two elements. |
2017-12-01 |
2023-08-13 |
human |
| Yong Lin, Jia-Jia Huang, Hans-Uwe Dahms, Jing-Jing Zhen, Xue-Ping Yin. Cell damage and apoptosis in the hepatopancreas of Eriocheir sinensis induced by cadmium. Aquatic toxicology (Amsterdam, Netherlands). vol 190. 2017-11-20. PMID:28750221. |
cadmium (cd) is one of the most common pollutants in the environment and it is known to cause a range of tissue damages and apoptosis in invertebrates. |
2017-11-20 |
2023-08-13 |
Not clear |
| M Sapmaz-Metin, Y Topcu-Tarladacalisir, I Kurt-Omurlu, B Karaoz Weller, S Unsal-Ata. A morphological study of uterine alterations in mice due to exposure to cadmium. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 92. issue 4. 2017-11-02. PMID:28426261. |
we found that 60 day cd exposure increased apoptosis in the endometrium, which may affect the receptivity of the uterus for implantation. |
2017-11-02 |
2023-08-13 |
mouse |
| Gamze Varan, Selin Öncül, Ayşe Ercan, Juan M Benito, Carmen Ortiz Mellet, Erem Bilenso. Cholesterol-Targeted Anticancer and Apoptotic Effects of Anionic and Polycationic Amphiphilic Cyclodextrin Nanoparticles. Journal of pharmaceutical sciences. vol 105. issue 10. 2017-10-31. PMID:27488900. |
in conclusion, blank amphiphilic cd nanoparticles induced apoptosis through mitochondrial pathway targeted to cholesterol microdomains in cancer cell membrane. |
2017-10-31 |
2023-08-13 |
Not clear |
| Nazima Bashir, Vaihundam Manoharan, Selvaraj Miltonprab. Grape seed proanthocyanidins protects against cadmium induced oxidative pancreatitis in rats by attenuating oxidative stress, inflammation and apoptosis via Nrf-2/HO-1 signaling. The Journal of nutritional biochemistry. vol 32. 2017-10-09. PMID:27142746. |
cd intoxication revealed increased levels of proinflammatory cytokines (tnf-α, il1β and ifn-γ), reduced levels of cellular defense proteins (nrf-2 and ho-1) and glucose transporter (glut-2 and glut-4) along with the enhanced levels of signaling molecules of apoptosis (cleaved caspase-12/9/8/3) in the pancreas of cd-intoxicated rats. |
2017-10-09 |
2023-08-13 |
rat |
| Yijun Shen, Gang Li, Chunying Gu, Ben Chen, Aihua Chen, Hua Li, Bei Gao, Chencai Liang, Jingsong Wu, Tong Yang, Li Jin, Yong S. T0001, a variant of TNFR2-Fc fusion protein, exhibits improved Fc effector functions through increased binding to membrane-bound TNFα. PloS one. vol 12. issue 5. 2017-10-04. PMID:28542350. |
these results suggest that t0001 may not only exert improved efficacy in treating rheumatoid arthritis (ra) because of its high affinity to stnfα but also has a therapeutic potential in cd and uc due to its increased binding to mtnfα with resultant fc-associated functions (adcc, in particular) and improved apoptosis. |
2017-10-04 |
2023-08-13 |
human |
| Yan-Ming Xu, Yang-Min Gao, Dan-Dan Wu, Fei-Yuan Yu, Zhong-Sheng Zang, Lei Yang, Yue Yao, Na-Li Cai, Yuan Zhou, Jen-Fu Chiu, Yick-Pang Ching, Andy T Y La. Aberrant cytokine secretion and zinc uptake in chronic cadmium-exposed lung epithelial cells. Proteomics. Clinical applications. vol 11. issue 3-4. 2017-10-02. PMID:27801555. |
our previous results showed that cadmium (cd)-adapted lung epithelial cells (lecs) developed resistance to apoptosis due to non-responsiveness of the c-jun n-terminal kinase pathway and augmented expression of cytokeratin 8. |
2017-10-02 |
2023-08-13 |
Not clear |
| Keum-Young So, Sang-Hun Kim, Ki-Tae Jung, Hyun-Young Lee, Seon-Hee O. MAPK/JNK1 activation protects cells against cadmium-induced autophagic cell death via differential regulation of catalase and heme oxygenase-1 in oral cancer cells. Toxicology and applied pharmacology. vol 332. 2017-09-25. PMID:28782507. |
exposing yd8 cells to cd reduced the expression levels of catalase and superoxide dismutase 1/2 and induced the expression of ho-1 as well as autophagy and apoptosis, which were reversed by n-acetyl-l-cysteine (nac). |
2017-09-25 |
2023-08-13 |
Not clear |
| Jianqiao Chen, Tingru Pan, Na Wan, Zhepeng Sun, Ziwei Zhang, Shu L. Cadmium-induced endoplasmic reticulum stress in chicken neutrophils is alleviated by selenium. Journal of inorganic biochemistry. vol 170. 2017-09-18. PMID:28249225. |
cadmium (cd) decreases immune function and induces apoptosis of immune cells. |
2017-09-18 |
2023-08-13 |
chicken |
| Todd M Everson, Maya Kappil, Ke Hao, Brian P Jackson, Tracy Punshon, Margaret R Karagas, Jia Chen, Carmen J Marsi. Maternal exposure to selenium and cadmium, fetal growth, and placental expression of steroidogenic and apoptotic genes. Environmental research. vol 158. 2017-08-28. PMID:28662449. |
cadmium (cd) and selenium (se) antagonistically influence redox balance and apoptotic signaling, with cd potentially promoting and se inhibiting oxidative stress and apoptosis. |
2017-08-28 |
2023-08-13 |
Not clear |
| Ruijie Zhang, Yu Zhu, Xiaoqing Dong, Beibei Liu, Nana Zhang, Xiaoxue Wang, Lei Liu, Chong Xu, Shile Huang, Long Che. Celastrol Attenuates Cadmium-Induced Neuronal Apoptosis via Inhibiting Ca Journal of cellular physiology. vol 232. issue 8. 2017-08-07. PMID:27891586. |
celastrol attenuates cadmium-induced neuronal apoptosis via inhibiting ca cadmium (cd), an environmental and industrial pollutant, affects the nervous system and consequential neurodegenerative disorders. |
2017-08-07 |
2023-08-13 |
Not clear |
| Xiaocui Chen, Jing Li, Zuowang Cheng, Yinghua Xu, Xia Wang, Xiaorui Li, Dongmei Xu, Carolyn M Kapron, Ju Li. Low Dose Cadmium Inhibits Proliferation of Human Renal Mesangial Cells via Activation of the JNK Pathway. International journal of environmental research and public health. vol 13. issue 10. 2017-08-03. PMID:27739415. |
cd treatment also induces a decrease in proliferation and an increase in apoptosis of hrmcs, but only the decrease in hrmc proliferation was reversed by pretreatment with sp600125, an inhibitor of the jnk pathway. |
2017-08-03 |
2023-08-13 |
human |
| Chong Xu, Xiaoxue Wang, Chenjian Gu, Hai Zhang, Ruijie Zhang, Xiaoqing Dong, Chunxiao Liu, Xiaoyu Hu, Xiang Ji, Shile Huang, Long Che. Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway. Journal of neurochemistry. vol 141. issue 1. 2017-07-13. PMID:28129433. |
recently, we have reported that cadmium (cd) activates c-jun n-terminal kinase (jnk) pathway leading to neuronal cell death by inducing ros inactivation of protein phosphatase 5 (pp5), and celastrol prevents cd-activated jnk pathway against neuronal apoptosis. |
2017-07-13 |
2023-08-13 |
Not clear |
| Chong Xu, Xiaoxue Wang, Chenjian Gu, Hai Zhang, Ruijie Zhang, Xiaoqing Dong, Chunxiao Liu, Xiaoyu Hu, Xiang Ji, Shile Huang, Long Che. Celastrol ameliorates Cd-induced neuronal apoptosis by targeting NOX2-derived ROS-dependent PP5-JNK signaling pathway. Journal of neurochemistry. vol 141. issue 1. 2017-07-13. PMID:28129433. |
therefore, we hypothesized that celastrol could hinder cd induction of ros-dependent pp5-jnk signaling pathway from apoptosis in neuronal cells. |
2017-07-13 |
2023-08-13 |
Not clear |
| Chong Xu, Xiaoxue Wang, Yu Zhu, Xiaoqing Dong, Chunxiao Liu, Hai Zhang, Lei Liu, Shile Huang, Long Che. Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A. Neuropharmacology. vol 105. 2017-06-22. PMID:26805420. |
over-expression of wild-type pp2a reinforced rapamycin or mito-tempo suppression of activated jnk and erk1/2 pathways, as well as ros production and apoptosis in neuronal cells in response to cd. |
2017-06-22 |
2023-08-13 |
Not clear |
| Beibei Fu, Jiamin Zhao, Wei Peng, Haibo Wu, Yong Zhan. Resveratrol rescues cadmium-induced mitochondrial injury by enhancing transcriptional regulation of PGC-1α and SOD2 via the Sirt3/FoxO3a pathway in TCMK-1 cells. Biochemical and biophysical research communications. vol 486. issue 1. 2017-06-19. PMID:28286268. |
importantly, mechanistic study revealed that erk1/2 activation was associated with increased apoptosis induced by cd, resveratrol suppressed cd-induced apoptosis in mice kidney. |
2017-06-19 |
2023-08-13 |
mouse |
| Wenxia Bai, Jian'an Bai, Yanhai Li, Delong Tian, Ruihua Sh. Microtubule-associated protein 1S-related autophagy inhibits apoptosis of intestinal epithelial cells via Wnt/β-catenin signaling in Crohn's disease. Biochemical and biophysical research communications. vol 485. issue 3. 2017-06-12. PMID:28188784. |
taken together, our results suggested that map1s were up-regulated among cd patients and map1s-related autophagy inhibits apoptosis of intestinal epithelial cells (iecs) through wnt/β-catenin signaling pathway which might play a vital role in the protection of intestinal mucosal barrier and inhibition the progression of cd. |
2017-06-12 |
2023-08-13 |
Not clear |
| K M Kiran Kumar, M Naveen Kumar, Rajeshwari H Patil, Rashmi Nagesh, Shubha M Hegde, K Kavya, R L Babu, Govindarajan T Ramesh, S Chidananda Sharm. Cadmium induces oxidative stress and apoptosis in lung epithelial cells. Toxicology mechanisms and methods. vol 26. issue 9. 2017-06-02. PMID:27687512. |
however, the role of cd in oxidative stress and apoptosis is less understood. |
2017-06-02 |
2023-08-13 |
Not clear |
| Hao Wang, Anna K Engstrom, Zhengui Xi. Cadmium impairs the survival and proliferation of cultured adult subventricular neural stem cells through activation of the JNK and p38 MAP kinases. Toxicology. vol 380. 2017-05-12. PMID:28163110. |
in this study, we report that low-level cd exposure decreases cell number, induces apoptosis, and inhibits cell proliferation in svz-anpcs. |
2017-05-12 |
2023-08-13 |
mouse |
| Hao Wang, Anna K Engstrom, Zhengui Xi. Cadmium impairs the survival and proliferation of cultured adult subventricular neural stem cells through activation of the JNK and p38 MAP kinases. Toxicology. vol 380. 2017-05-12. PMID:28163110. |
cd treatment did not cause cell loss or apoptosis in svz-anpcs prepared from transgenic mice null for the neural-specific jnk3 isoform. |
2017-05-12 |
2023-08-13 |
mouse |