| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Keum-Young So, Seon-Hee O. Cadmium-induced heme-oxygenase-1 expression plays dual roles in autophagy and apoptosis and is regulated by both PKC-δ and PKB/Akt activation in NRK52E kidney cells. Toxicology. vol 370. 2017-05-10. PMID:27658547. |
these results indicate that ho-1 induced by cd exposure is regulated by pkc-δ, p-ser gsk3αβ, and pkb/akt, which restrain autophagic cell death, but mildly induce apoptosis in nrk52e cells. |
2017-05-10 |
2023-08-13 |
Not clear |
| Minyi Huang, Li Su, Limin Yang, Liangliang Zhu, Zhaowen Liu, Renyan Dua. Effect of exogenous TGF-β1 on the cadmium-induced nephrotoxicity by inhibiting apoptosis of proximal tubular cells through PI3K-AKT-mTOR signaling pathway. Chemico-biological interactions. vol 269. 2017-05-09. PMID:28342888. |
cadmium (cd), one of the heavy metals, could induce apoptosis of proximal tubular cells in many experimental models and lead to damage the human kidney. |
2017-05-09 |
2023-08-13 |
human |
| Shweta Shrivastava, Manish Kumar Jeengar, Dinesh Thummuri, Alexey Koval, Vladimir L Katanaev, Srujan Marepally, V G M Naid. Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition. BioFactors (Oxford, England). vol 43. issue 2. 2017-05-08. PMID:27580587. |
the results show that cd exhibits cytotoxicity by inducing apoptosis and cell cycle arrest in tnbc cells via modulation of bcl-2, bax, cyt-c, cleaved caspase-3, and parp. |
2017-05-08 |
2023-08-13 |
mouse |
| Jing-Ya Zeng, Jing-Jing Du, Ying Pan, Jian Wu, Hai-Liang Bi, Bao-Hong Cui, Tai-Yu Zhai, Yong Sun, Yi-Hua Su. Calcium-Sensing Receptor in Human Peripheral Blood T Lymphocytes Is Involved in the AMI Onset and Progression through the NF-κB Signaling Pathway. International journal of molecular sciences. vol 17. issue 9. 2017-05-01. PMID:27563892. |
meanwhile, the apoptosis rate of cd(3+), cd(4+) and cd(8+) t lymphocytes also increased. |
2017-05-01 |
2023-08-13 |
human |
| Mehmet Fatih Sönmez, Simge Tasciogl. Protective effects of grape seed extract on cadmium-induced testicular damage, apoptosis, and endothelial nitric oxide synthases expression in rats. Toxicology and industrial health. vol 32. issue 8. 2017-04-17. PMID:25614582. |
this study aims to evaluate the protective effect of grape seed proanthocyanidin extract (gspe) on cadmium (cd)-induced testicular apoptosis, endothelial nitric oxide synthases (enos) expression, and toxicity in rats. |
2017-04-17 |
2023-08-13 |
rat |
| Xuezhong Liu, Yiran Zhang, Yi Wang, Yuan Yan, Jiajing Wang, Jianhong Gu, Bianjian Chun, Zongping Li. Investigation of cadmium-induced apoptosis and the protective effect of N-acetylcysteine in BRL 3A cells. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27175572. |
the aims of the present study were to investigate the effect of cadmium (cd)‑induced apoptosis and determine the protective effect of n‑acetylcysteine (nac) in brl 3a cells. |
2017-04-06 |
2023-08-13 |
Not clear |
| Xuezhong Liu, Yiran Zhang, Yi Wang, Yuan Yan, Jiajing Wang, Jianhong Gu, Bianjian Chun, Zongping Li. Investigation of cadmium-induced apoptosis and the protective effect of N-acetylcysteine in BRL 3A cells. Molecular medicine reports. vol 14. issue 1. 2017-04-06. PMID:27175572. |
cd induced apoptosis through the mitochondrial and fasl pathways in the brl 3a cells, and nac exerted a protective effect against cd‑induced damage. |
2017-04-06 |
2023-08-13 |
Not clear |
| Chunyan Zong, Xiaoke Nie, Dongmei Zhang, Qianqian Ji, Yongwei Qin, Liang Wang, Dawei Jiang, Chen Gong, Yifei Liu, Guoxiong Zho. Up regulation of glyoxylate reductase/hydroxypyruvate reductase (GRHPR) is associated with intestinal epithelial cells apoptosis in TNBS-induced experimental colitis. Pathology, research and practice. vol 212. issue 5. 2017-03-23. PMID:26997491. |
thus, grhpr might play an important role in regulating iecs apoptosis, and might be a potential therapeutic target for cd. |
2017-03-23 |
2023-08-13 |
mouse |
| Hongyan Zhang, Liqun Li, Yifan Wang, Fengyun Dong, Xiaocui Chen, Fuhong Liu, Dongmei Xu, Fan Yi, Carolyn M Kapron, Ju Li. NF-κB signaling maintains the survival of cadmium-exposed human renal glomerular endothelial cells. International journal of molecular medicine. vol 38. issue 2. 2017-03-06. PMID:27315281. |
we found that cd activates the nuclear factor-κb (nf-κb) pathway without inducing the apoptosis of hrgecs. |
2017-03-06 |
2023-08-13 |
human |
| Yuanxiang Jin, Songbin Zhang, Runhua Tao, Jie Huang, Xingzhi He, Lanya Qu, Zhengwei F. Oral exposure of mice to cadmium (II), chromium (VI) and their mixture induce oxidative- and endoplasmic reticulum-stress mediated apoptosis in the livers. Environmental toxicology. vol 31. issue 6. 2017-03-01. PMID:25409916. |
these results suggested that a long period exposure of mice to cd or cr has the potential to elicit oxidative- and er-stress mediated apoptosis in their livers. |
2017-03-01 |
2023-08-13 |
mouse |
| Lanlan Xu, Xiao Peng, Deliang Yu, Chenglong Ji, Jianmin Zhao, Huifeng W. Proteomic responses reveal the differential effects induced by cadmium in mussels Mytilus galloprovincialis at early life stages. Fish & shellfish immunology. vol 55. 2017-03-01. PMID:27302865. |
in juvenile mussels, cd exposure also induced clear apoptosis. |
2017-03-01 |
2023-08-13 |
Not clear |
| Chinnarasu Sivaprakasam, Vasanthi Nachiappa. Modulatory effect of cadmium on the expression of phospholipase A2 and proinflammatory genes in rat testis. Environmental toxicology. vol 31. issue 10. 2017-02-22. PMID:25808797. |
hence, this study explored the testes under cd toxicity and observed alterations in pla2 s and mitochondrial membrane composition/function and further explored the impact of these alterations on proinflammation and apoptosis. |
2017-02-22 |
2023-08-13 |
rat |
| Blanka Jancekova, Eva Ondrouskova, Lucia Knopfova, Jan Smarda, Petr Bene. Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-21. PMID:26867770. |
cd has been repeatedly reported to act as key mediator of apoptosis induced by various chemotherapeutics. |
2017-02-21 |
2023-08-13 |
human |
| Blanka Jancekova, Eva Ondrouskova, Lucia Knopfova, Jan Smarda, Petr Bene. Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-21. PMID:26867770. |
for this purpose, mda-mb-231 breast carcinoma cells with an increased level of wt cd (cd) or mutant enzymatically inactive cd (Δcd) were subjected to trail and the frequency of apoptosis was determined. |
2017-02-21 |
2023-08-13 |
human |
| Blanka Jancekova, Eva Ondrouskova, Lucia Knopfova, Jan Smarda, Petr Bene. Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-21. PMID:26867770. |
our results show that cd facilitates the trail-induced apoptosis of mda-mb-231 breast cancer cells in enzymatic activity-dependent manner. |
2017-02-21 |
2023-08-13 |
human |
| Blanka Jancekova, Eva Ondrouskova, Lucia Knopfova, Jan Smarda, Petr Bene. Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-21. PMID:26867770. |
analysis of the potential substrates specifically cleaved by cd during the trail-induced apoptosis confirmed caspase-8 and bid proteins as the cd targets. |
2017-02-21 |
2023-08-13 |
human |
| Blanka Jancekova, Eva Ondrouskova, Lucia Knopfova, Jan Smarda, Petr Bene. Enzymatically active cathepsin D sensitizes breast carcinoma cells to TRAIL. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 37. issue 8. 2017-02-21. PMID:26867770. |
moreover, in search for protein regulators of apoptosis that can be cleaved by cd at physiologically relevant ph, we identified the bcl-2 protein as a suitable candidate. |
2017-02-21 |
2023-08-13 |
human |
| Huabin Cao, Bing Xia, Mengmeng Zhang, Yilin Liao, Zhi Yang, Guoliang Hu, Caiying Zhan. Changes of Antioxidant Function and the mRNA Expression Levels of Apoptosis Genes in Duck Ovaries Caused by Molybdenum or/and Cadmium. Biological trace element research. vol 171. issue 2. 2017-02-07. PMID:26446861. |
the results from the present study indicated that mo or/and cd caused oxidative stress and apoptosis in duck ovaries. |
2017-02-07 |
2023-08-13 |
Not clear |
| Huabin Cao, Bing Xia, Mengmeng Zhang, Yilin Liao, Zhi Yang, Guoliang Hu, Caiying Zhan. Changes of Antioxidant Function and the mRNA Expression Levels of Apoptosis Genes in Duck Ovaries Caused by Molybdenum or/and Cadmium. Biological trace element research. vol 171. issue 2. 2017-02-07. PMID:26446861. |
combination of mo and cd showed additive or synergistic effect leading to apoptosis and oxidative stress, and the pathway might be the mitochondrial pathway. |
2017-02-07 |
2023-08-13 |
Not clear |
| Qingyang Xiao, Caiying Zhang, Xiaolong Gu, Yu Zhuang, Junrong Luo, Ping Liu, Xiaoquan Guo, Guoliang Hu, Huabin Ca. Varying Dietary Levels of Molybdenum Inducing Cell Apoptosis of Spleen Under Cadmium Stress in Caprine. Biological trace element research. vol 172. issue 1. 2017-02-03. PMID:26585322. |
the present experiment aims at evaluating chronic toxic effects of the combination of cadmium (cd) and molybdenum (mo) according to residual element contents, apoptosis gene expression, and ultrastructure and histopathology changes of caprine spleen. |
2017-02-03 |
2023-08-13 |
Not clear |