| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Liu, Hongyan Zhao, Yi Wang, Chenyang Jiang, Pengpeng Xia, Jianhong Gu, Xuezhong Liu, Jianchun Bian, Yan Yuan, Zongping Li. Calcium-calmodulin signaling elicits mitochondrial dysfunction and the release of cytochrome c during cadmium-induced apoptosis in primary osteoblasts. Toxicology letters. vol 224. issue 1. 2014-02-06. PMID:24144892. |
although cd is known to induce apoptosis in many human organ systems, the mechanism that underlies its toxicity in primary osteoblasts (obs) is not yet established. |
2014-02-06 |
2023-08-12 |
human |
| Wei Liu, Hongyan Zhao, Yi Wang, Chenyang Jiang, Pengpeng Xia, Jianhong Gu, Xuezhong Liu, Jianchun Bian, Yan Yuan, Zongping Li. Calcium-calmodulin signaling elicits mitochondrial dysfunction and the release of cytochrome c during cadmium-induced apoptosis in primary osteoblasts. Toxicology letters. vol 224. issue 1. 2014-02-06. PMID:24144892. |
in the present study, we confirmed that cd induced apoptosis in obs isolated from the craniums of fetal sprague-dawley rats. |
2014-02-06 |
2023-08-12 |
human |
| Wei Liu, Hongyan Zhao, Yi Wang, Chenyang Jiang, Pengpeng Xia, Jianhong Gu, Xuezhong Liu, Jianchun Bian, Yan Yuan, Zongping Li. Calcium-calmodulin signaling elicits mitochondrial dysfunction and the release of cytochrome c during cadmium-induced apoptosis in primary osteoblasts. Toxicology letters. vol 224. issue 1. 2014-02-06. PMID:24144892. |
our findings provide new insights into the mechanisms underlying apoptosis in obs following exposure to cd. |
2014-02-06 |
2023-08-12 |
human |
| Karl A Dunne, Amr Allam, Anne McIntosh, Stephanie A Houston, Vuk Cerovic, Carl S Goodyear, Andrew J Roe, Scott A Beatson, Simon W Milling, Daniel Walker, Daniel M Wal. Increased S-nitrosylation and proteasomal degradation of caspase-3 during infection contribute to the persistence of adherent invasive Escherichia coli (AIEC) in immune cells. PloS one. vol 8. issue 7. 2014-02-03. PMID:23861899. |
in addition to the autophagic genetic defects that are linked to cd, this delay in apoptosis mediated in aiec infected cells through increased degradation of caspase-3, may be an essential factor in its prolonged persistence in cd patients. |
2014-02-03 |
2023-08-12 |
Not clear |
| Marzia Dolcino, Giovanna Zanoni, Caterina Bason, Elisa Tinazzi, Elisa Boccola, Enrico Valletta, Giovanna Contreas, Claudio Lunardi, Antonio Puccett. A subset of anti-rotavirus antibodies directed against the viral protein VP7 predicts the onset of celiac disease and induces typical features of the disease in the intestinal epithelial cell line T84. Immunologic research. vol 56. issue 2-3. 2014-01-24. PMID:23572432. |
the gene-array analysis showed that purified anti-rotavirus vp7 antibodies modulate genes that are involved in apoptosis, inflammation, and alteration of the epithelial barrier integrity in intestinal epithelial cells, all typical features of cd. |
2014-01-24 |
2023-08-12 |
Not clear |
| Arne Mehrkens, M Zia Karim, Sarah Kim, Raychel Hilario, Michael G Fehlings, William Mark Erwi. Canine notochordal cell-secreted factors protect murine and human nucleus pulposus cells from apoptosis by inhibition of activated caspase-9 and caspase-3/7. Evidence-based spine-care journal. vol 4. issue 2. 2014-01-17. PMID:24436715. |
with the presented work, we have investigated if nonchondrodystrophic (ncd) canine intervertebral disc (ivd)-derived notochordal cell conditioned medium (nccm) and chondrodystrophic (cd) canine ivd-derived conditioned medium (cdcm) are able to protect murine and human np cells from apoptosis. |
2014-01-17 |
2023-08-12 |
mouse |
| Nicola Franchi, Loriano Ballari. Influence of cadmium on the morphology and functionality of haemocytes in the compound ascidian Botryllus schlosseri. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 158. issue 1. 2014-01-09. PMID:23603692. |
the fraction of cells showing positivity for the lysosomal enzyme acid phosphatase is also reduced in the presence of cd, whereas the number of cells responsive to the annexin-v assay and showing chromatin condensation increases, suggesting a metal-dependent induction of apoptosis in exposed cells. |
2014-01-09 |
2023-08-12 |
Not clear |
| Xia Wang, Dong-yun Sun, Xiang-ting Wan. [Protective effects of chailing decoction on cyclosporine A induced chronic renal injury and its mechanisms]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 32. issue 8. 2013-12-30. PMID:23173258. |
to observe the effects of chailing decoction (cd) on transforming growth factor-beta1 (tgf-beta1), connective tissue growth factor (ctgf), renal cell apoptosis and proliferation in rats with chronic cyclosporine a nephropathy (ccn), and to explore its possible mechanism for inhibiting renal fibrosis. |
2013-12-30 |
2023-08-12 |
rat |
| Hironori Kato, Ryohei Katoh, Masanori Kitamur. Dual regulation of cadmium-induced apoptosis by mTORC1 through selective induction of IRE1 branches in unfolded protein response. PloS one. vol 8. issue 5. 2013-12-23. PMID:23696882. |
knockdown of tsc2, a negative regulator of mtorc1, caused activation of mtorc1 and enhanced cd induction of the ire1-jnk pathway and apoptosis without affecting other upr branches. |
2013-12-23 |
2023-08-12 |
mouse |
| Maki Tokumoto, Masahiko Sato. [Cadmium induces p53-dependent apoptosis through the inhibition of Ube2d family gene expression]. Nihon eiseigaku zasshi. Japanese journal of hygiene. vol 67. issue 4. 2013-12-17. PMID:23095357. |
cd markedly increased p53 protein level and induced p53 phosphorylation and apoptosis in the cells. |
2013-12-17 |
2023-08-12 |
mouse |
| Maki Tokumoto, Masahiko Sato. [Cadmium induces p53-dependent apoptosis through the inhibition of Ube2d family gene expression]. Nihon eiseigaku zasshi. Japanese journal of hygiene. vol 67. issue 4. 2013-12-17. PMID:23095357. |
in vivo studies showed that chronic cd exposure also suppressed ube2d family gene expression and induced p53 accumulation and apoptosis in the renal tubules of the mouse kidney. |
2013-12-17 |
2023-08-12 |
mouse |
| Maki Tokumoto, Masahiko Sato. [Cadmium induces p53-dependent apoptosis through the inhibition of Ube2d family gene expression]. Nihon eiseigaku zasshi. Japanese journal of hygiene. vol 67. issue 4. 2013-12-17. PMID:23095357. |
these findings suggest that cd causes p53-dependent apoptosis due to the inhibition of p53 degradation through the down-regulation of ube2d family genes in nrk-52e cells and mouse kidney. |
2013-12-17 |
2023-08-12 |
mouse |
| Chunqiang Wang, Wei Ma, Yuhong S. NF-κB pathway contributes to cadmium-induced apoptosis of porcine granulosa cells. Biological trace element research. vol 153. issue 1-3. 2013-12-16. PMID:23575899. |
to better understand the mechanism of cadmium (cd)-induced apoptosis of porcine granulosa cells, we examined the nuclear factor-kappa b (nf-κb) p65 subunits intracellular translocation and the expression of some downstream apoptotic-related genes. |
2013-12-16 |
2023-08-12 |
Not clear |
| Jin-Long Li, Cheng-Yu Jiang, Shu Li, Shi-Wen X. Cadmium induced hepatotoxicity in chickens (Gallus domesticus) and ameliorative effect by selenium. Ecotoxicology and environmental safety. vol 96. 2013-11-18. PMID:23906702. |
histological and ultrastructural changes in the liver, the concentrations of cd and se, the lipid peroxidation (lpo) and nitric oxide (no) production, the activities of the antioxidants superoxide dismutase (sod) and glutathione peroxidase (gpx), nitric oxide synthase (nos) activities and apoptosis were determined. |
2013-11-18 |
2023-08-12 |
Not clear |
| Jin-Long Li, Cheng-Yu Jiang, Shu Li, Shi-Wen X. Cadmium induced hepatotoxicity in chickens (Gallus domesticus) and ameliorative effect by selenium. Ecotoxicology and environmental safety. vol 96. 2013-11-18. PMID:23906702. |
concurrent treatment with se reduced the cd-induced liver histopathological changes, oxidative stress, overexpression of no and apoptosis, suggesting that the toxic effects of cd on the liver is partly ameliorated by inorganic se. |
2013-11-18 |
2023-08-12 |
Not clear |
| Andrea Cossu, Livia Biancone, Marta Ascolani, Francesco Pallone, Monica Boirivan. "In vitro" azathioprine-induced changes in peripheral T cell apoptosis and IFN-γ production associate with drug response in patients with Crohn's Disease. Journal of Crohn's & colitis. vol 7. issue 6. 2013-11-05. PMID:22840925. |
we studied the effect of thiopurines on "in vitro" t cell apoptosis, ifn-γ and il-10 production in a group of cd patients with known response to a previous treatment with aza. |
2013-11-05 |
2023-08-12 |
Not clear |
| Qiwen Wang, Jiaqiao Zhu, Kangbao Zhang, Chenyang Jiang, Yi Wang, Yan Yuan, Jianchun Bian, Xuezhong Liu, Jianhong Gu, Zongping Li. Induction of cytoprotective autophagy in PC-12 cells by cadmium. Biochemical and biophysical research communications. vol 438. issue 1. 2013-11-04. PMID:23880342. |
laboratory data have demonstrated that cadmium (cd) may induce neuronal apoptosis. |
2013-11-04 |
2023-08-12 |
Not clear |
| Zhen Zhang, Caifeng Bi, Daniela Buac, Yuhua Fan, Xia Zhang, Jian Zuo, Pengfei Zhang, Nan Zhang, Lili Dong, Q Ping Do. Organic cadmium complexes as proteasome inhibitors and apoptosis inducers in human breast cancer cells. Journal of inorganic biochemistry. vol 123. 2013-10-22. PMID:23499788. |
although cadmium (cd) is a widespread environmental contaminant and human carcinogen, our studies indicate an organic cd complex to be a potent inhibitor of proteasomal chymotrypsin-like (ct-like) activity, further capable of inducing apoptosis in a cancer cell-specific manner. |
2013-10-22 |
2023-08-12 |
human |
| Wakako Ohyama, Emiko Okada, Yohei Fujiishi, Kazunori Narumi, Nobuyoshi Yasutak. In vivo rat glandular stomach and colon micronucleus tests: Kinetics of micronucleated cells, apoptosis, and cell proliferation in the target tissues after a single oral administration of stomach- or colon-carcinogens. Mutation research. vol 755. issue 2. 2013-10-17. PMID:23827781. |
in the present study, our aim was to demonstrate the characteristics of the glandular stomach and colon mn tests by analyzing time-related changes in mn frequencies, apoptosis and cell proliferation in the target tissues of male cd (sd) rats that were orally administered a single dose of a stomach- or colon-targeted carcinogen, i.e., n-nitroso-n-methylurea (mnu) or n-methyl-n'-nitro-n-nitrosoguanidine (mnng) for the stomach and 1,2-dimethylhydrazine dihydrochloride (dmh) for the colon. |
2013-10-17 |
2023-08-12 |
rat |
| Neelima Pathak, Sumonto Mitra, Shashi Khandelwa. Cadmium induces thymocyte apoptosis via caspase-dependent and caspase-independent pathways. Journal of biochemical and molecular toxicology. vol 27. issue 3. 2013-09-23. PMID:23315796. |
based on our recent findings that 25 µm cadmium triggers oxidative stress-mediated caspase-dependent apoptosis in murine thymocytes, this study is designed to explore whether cd also induces caspase-independent apoptosis. |
2013-09-23 |
2023-08-12 |
Not clear |