| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jessica R Napolitano, Ming-Jie Liu, Shengying Bao, Melissa Crawford, Patrick Nana-Sinkam, Estelle Cormet-Boyaka, Daren L Knoel. Cadmium-mediated toxicity of lung epithelia is enhanced through NF-κB-mediated transcriptional activation of the human zinc transporter ZIP8. American journal of physiology. Lung cellular and molecular physiology. vol 302. issue 9. 2012-06-29. PMID:22345571. |
tnf-α treatment of primary human lung epithelia and a549 cells induced zip8 expression, resulting in significantly higher cell death attributable to both apoptosis and necrosis following cd exposure. |
2012-06-29 |
2023-08-12 |
human |
| Zhen Wang, Hua Wang, Zhong Mei Xu, Yan-Li Ji, Yuan-Hua Chen, Zhi-Hui Zhang, Cheng Zhang, Xiu-Hong Meng, Mei Zhao, De-Xiang X. Cadmium-induced teratogenicity: association with ROS-mediated endoplasmic reticulum stress in placenta. Toxicology and applied pharmacology. vol 259. issue 2. 2012-06-28. PMID:22252055. |
in addition, maternal cd exposure markedly repressed cell proliferation and increased apoptosis in placenta. |
2012-06-28 |
2023-08-12 |
mouse |
| Yan-Li Ji, Hua Wang, Can Meng, Xian-Feng Zhao, Cheng Zhang, Ying Zhang, Mei Zhao, Yuan-Hua Chen, Xiu-Hong Meng, De-Xiang X. Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes. Journal of pineal research. vol 52. issue 1. 2012-06-18. PMID:21793897. |
cadmium (cd) is a testicular toxicant and induces germ cell apoptosis. |
2012-06-18 |
2023-08-12 |
mouse |
| Yan-Li Ji, Hua Wang, Can Meng, Xian-Feng Zhao, Cheng Zhang, Ying Zhang, Mei Zhao, Yuan-Hua Chen, Xiu-Hong Meng, De-Xiang X. Melatonin alleviates cadmium-induced cellular stress and germ cell apoptosis in testes. Journal of pineal research. vol 52. issue 1. 2012-06-18. PMID:21793897. |
as expected, acute cd exposure resulted in germ cell apoptosis in testes, as determined by terminal dutp nick-end labeling (tunel) staining. |
2012-06-18 |
2023-08-12 |
mouse |
| Jing Qiu, Guoying Zhu, Xiao Chen, Chunlin Shao, Shuzhu G. Combined effects of γ-irradiation and cadmium exposures on osteoblasts in vitro. Environmental toxicology and pharmacology. vol 33. issue 2. 2012-06-12. PMID:22209727. |
low concentrations of cd exposure had no obvious influence on cell viability, alp activity and apoptosis. |
2012-06-12 |
2023-08-12 |
Not clear |
| Jing Qiu, Guoying Zhu, Xiao Chen, Chunlin Shao, Shuzhu G. Combined effects of γ-irradiation and cadmium exposures on osteoblasts in vitro. Environmental toxicology and pharmacology. vol 33. issue 2. 2012-06-12. PMID:22209727. |
cd combined with γ-irradiation could obviously enhance osteoblast apoptosis and up-regulated caspase 3 mrna expression compared with those treated with cd or irradiation alone. |
2012-06-12 |
2023-08-12 |
Not clear |
| Jing Qiu, Guoying Zhu, Xiao Chen, Chunlin Shao, Shuzhu G. Combined effects of γ-irradiation and cadmium exposures on osteoblasts in vitro. Environmental toxicology and pharmacology. vol 33. issue 2. 2012-06-12. PMID:22209727. |
this study indicated that ionizing irradiation can enhance cd toxic effects on osteoblast viability and differentiation and apoptosis may play an important role in this progress. |
2012-06-12 |
2023-08-12 |
Not clear |
| Yan-Li Ji, Hua Wang, Xian-Feng Zhao, Qun Wang, Cheng Zhang, Ying Zhang, Mei Zhao, Yuan-Hua Chen, Xiu-Hong Meng, De-Xiang X. Crosstalk between endoplasmic reticulum stress and mitochondrial pathway mediates cadmium-induced germ cell apoptosis in testes. Toxicological sciences : an official journal of the Society of Toxicology. vol 124. issue 2. 2012-05-16. PMID:21908765. |
increasing evidence demonstrates that cd induces testicular germ cell apoptosis in rodent animals. |
2012-05-16 |
2023-08-12 |
mouse |
| Zheng-Guo Cui, Ryohei Ogawa, Jin-Lan Piao, Kei Hamazaki, Loreto B Feril, Akiko Shimomura, Takashi Kondo, Hidekuni Inader. Molecular mechanisms involved in the adaptive response to cadmium-induced apoptosis in human myelomonocytic lymphoma U937 cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 25. issue 8. 2012-04-13. PMID:21787858. |
we examined the molecular mechanisms involved in the adaptive response to cadmium (cd)-induced apoptosis in human myelomonocytic lymphoma u937 cells. |
2012-04-13 |
2023-08-12 |
human |
| Zheng-Guo Cui, Ryohei Ogawa, Jin-Lan Piao, Kei Hamazaki, Loreto B Feril, Akiko Shimomura, Takashi Kondo, Hidekuni Inader. Molecular mechanisms involved in the adaptive response to cadmium-induced apoptosis in human myelomonocytic lymphoma U937 cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 25. issue 8. 2012-04-13. PMID:21787858. |
in conclusion, pretreatment with low-dose cd inhibited apoptosis induced by high-dose cd. |
2012-04-13 |
2023-08-12 |
human |
| Farhat Jabeen, Abdul Shakoor Chaudhr. Effects of cadmium chloride and sodium selenite alone or in combination on the liver of male Sprague-Dawley rats assessed by different assays. Biological trace element research. vol 143. issue 2. 2012-04-12. PMID:21213067. |
the cd group showed increased dna damage, apoptosis and hepatic levels of lipid peroxidation and altered histology. |
2012-04-12 |
2023-08-12 |
rat |
| Farhat Jabeen, Abdul Shakoor Chaudhr. Effects of cadmium chloride and sodium selenite alone or in combination on the liver of male Sprague-Dawley rats assessed by different assays. Biological trace element research. vol 143. issue 2. 2012-04-12. PMID:21213067. |
the se group also showed dna damage, apoptosis and altered histology and reduced catalase activity, but it was less severe than the cd group. |
2012-04-12 |
2023-08-12 |
rat |
| Lan Wang, Tuan Xu, Wen-wen Lei, Dong-mei Liu, Ying-jun Li, Rui-jing Xuan, Jing-jin M. Cadmium-induced oxidative stress and apoptotic changes in the testis of freshwater crab, Sinopotamon henanense. PloS one. vol 6. issue 11. 2012-04-02. PMID:22132153. |
typical morphological characteristic and physiological changes of apoptosis were observed using a variety of methods (he staining, ao/eb double fluorescent staining, transmission electron microscope observation and dna fragmentation analysis), and the activities of caspase-3 and caspase-9 were increased in a concentration-dependent manner after cd exposure. |
2012-04-02 |
2023-08-12 |
cat |
| Lan Wang, Tuan Xu, Wen-wen Lei, Dong-mei Liu, Ying-jun Li, Rui-jing Xuan, Jing-jin M. Cadmium-induced oxidative stress and apoptotic changes in the testis of freshwater crab, Sinopotamon henanense. PloS one. vol 6. issue 11. 2012-04-02. PMID:22132153. |
these results led to the conclusion that cd could induced oxidative damage as well as apoptosis in the testis, and the apoptotic processes may be mediated via mitochondria-dependent apoptosis pathway by regulating the activities of caspase-3 and caspase-9. |
2012-04-02 |
2023-08-12 |
cat |
| Jae-Il Bang, Dong-Won Bae, Hyo-Sang Lee, Gautam K Deb, Myeong-Ok Kim, Sea-Hwan Sohn, Chang-Hee Han, Il-Keun Kon. Proteomic analysis of placentas from cloned cat embryos identifies a set of differentially expressed proteins related to oxidative damage, senescence and apoptosis. Proteomics. vol 11. issue 23. 2012-03-07. PMID:21932444. |
the abnormal expression of phb and cd correlated with the generation of reactive oxygen species, leading to decreased mitochondrial membrane potential and telomeric dna, which are associated with cellular senescence and apoptosis. |
2012-03-07 |
2023-08-12 |
cat |
| Chun-Hui Bao, Lu-Yi Wu, Yin Shi, Huan-Gan Wu, Hui-Rong Liu, Rong Zhang, Li-Qing Yu, Jin-Hai Wan. Moxibustion down-regulates colonic epithelial cell apoptosis and repairs tight junctions in rats with Crohn's disease. World journal of gastroenterology. vol 17. issue 45. 2012-02-13. PMID:22174545. |
to investigate the effects of moxibustion on down-regulation of the colonic epithelial cell apoptosis and repair of the tight junctions in rats with crohn's disease (cd). |
2012-02-13 |
2023-08-12 |
rat |
| A R Volpe, P Cesare, P Aimola, M Boscolo, G Valle, M Carmignan. Zinc opposes genotoxicity of cadmium and vanadium but not of lead. Journal of biological regulators and homeostatic agents. vol 25. issue 4. 2012-02-09. PMID:22217991. |
afterwards, cells were exposed for 3 days to subtoxic concentrations of lead (pb, 100 μm) or vanadium (+ 5, v, 2 μm) or cadmium (cd, 3 μm), slightly reducing, by themselves, cell proliferation and unaffecting cell viability and apoptosis. |
2012-02-09 |
2023-08-12 |
human |
| Sujuan Chen, Yijiao Xu, Baoshan Xu, Min Guo, Zhen Zhang, Lei Liu, Hongwei Ma, Zi Chen, Yan Luo, Shile Huang, Long Che. CaMKII is involved in cadmium activation of MAPK and mTOR pathways leading to neuronal cell death. Journal of neurochemistry. vol 119. issue 5. 2012-01-09. PMID:21933187. |
recently, we have shown that cd elevates intracellular free calcium ion ([ca(2+) ](i) ) level, leading to neuronal apoptosis partly by activating mitogen-activated protein kinases (mapk) and mammalian target of rapamycin (mtor) pathways. |
2012-01-09 |
2023-08-12 |
Not clear |
| b' Tatjana Srdi\\xc4\\x87-Raji\\xc4\\x87, Manja Zec, Tamara Todorovi\\xc4\\x87, Katarina An\\xc4\\x91elkovi\\xc4\\x87, Sini\\xc5\\xa1a Radulovi\\xc4\\x8. Non-substituted N-heteroaromatic selenosemicarbazone metal complexes induce apoptosis in cancer cells via activation of mitochondrial pathway. European journal of medicinal chemistry. vol 46. issue 9. 2012-01-03. PMID:21641698.' |
however, our data indicated that the increased phosphorylation of erk could be also one of the mechanism involved in the zn(ii), and cd(ii) complexes- induction of apoptosis. |
2012-01-03 |
2023-08-12 |
Not clear |
| b' Tatjana Srdi\\xc4\\x87-Raji\\xc4\\x87, Manja Zec, Tamara Todorovi\\xc4\\x87, Katarina An\\xc4\\x91elkovi\\xc4\\x87, Sini\\xc5\\xa1a Radulovi\\xc4\\x8. Non-substituted N-heteroaromatic selenosemicarbazone metal complexes induce apoptosis in cancer cells via activation of mitochondrial pathway. European journal of medicinal chemistry. vol 46. issue 9. 2012-01-03. PMID:21641698.' |
selenosemicarbazone complexes with cd(ii) and ni(ii), possess dual ability to induce apoptosis as well as necrosis, and might present an added advantage for inducing cell death in a diverse array of malignant cells. |
2012-01-03 |
2023-08-12 |
Not clear |