| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W P Mao, N N Zhang, F Y Zhou, W X Li, H Y Liu, J Feng, L Zhou, C J Wei, Y B Pan, Z J H. Cadmium directly induced mitochondrial dysfunction of human embryonic kidney cells. Human & experimental toxicology. vol 30. issue 8. 2011-12-07. PMID:20876161. |
cd could induce apoptosis of hek293 cells, and the mitochondria may play a key role. |
2011-12-07 |
2023-08-12 |
human |
| Joanna Rogalska, Barbara Pilat-Marcinkiewicz, Malgorzata M Brzósk. Protective effect of zinc against cadmium hepatotoxicity depends on this bioelement intake and level of cadmium exposure: a study in a rat model. Chemico-biological interactions. vol 193. issue 3. 2011-11-09. PMID:21627960. |
the treatment with cd led to, dependent on the exposure level, pathological changes in the liver, including enhanced apoptosis and induction of inflammatory and necrotic processes. |
2011-11-09 |
2023-08-12 |
human |
| Arie Levine, Dan Turne. Combined azithromycin and metronidazole therapy is effective in inducing remission in pediatric Crohn's disease. Journal of Crohn's & colitis. vol 5. issue 3. 2011-11-08. PMID:21575885. |
we aimed to assess whether azithromycin based therapy is effective in inducing remission in cd, due to its effect in inducing apoptosis and efficacy against biofilms and intracellular bacteria. |
2011-11-08 |
2023-08-12 |
Not clear |
| Rebeca Santaolalla, Josep Mañé, Elisabet Pedrosa, Violeta Lorén, Fernando Fernández-Bañares, Josefa Mallolas, Anna Carrasco, Antonio Salas, Mercè Rosinach, Montserrat Forné, Jorge C Espinós, Carme Loras, Michael Donovan, Pere Puig, Miriam Mañosa, Miquel A Gassull, Josep M Viver, Maria Estev. Apoptosis resistance of mucosal lymphocytes and IL-10 deficiency in patients with steroid-refractory Crohn's disease. Inflammatory bowel diseases. vol 17. issue 7. 2011-10-28. PMID:21674705. |
apoptosis resistance of t-cells is considered an abnormality of immune pathways in crohn's disease (cd). |
2011-10-28 |
2023-08-12 |
Not clear |
| Rebeca Santaolalla, Josep Mañé, Elisabet Pedrosa, Violeta Lorén, Fernando Fernández-Bañares, Josefa Mallolas, Anna Carrasco, Antonio Salas, Mercè Rosinach, Montserrat Forné, Jorge C Espinós, Carme Loras, Michael Donovan, Pere Puig, Miriam Mañosa, Miquel A Gassull, Josep M Viver, Maria Estev. Apoptosis resistance of mucosal lymphocytes and IL-10 deficiency in patients with steroid-refractory Crohn's disease. Inflammatory bowel diseases. vol 17. issue 7. 2011-10-28. PMID:21674705. |
thus, our aim was to assess the apoptosis of mononuclear cells and pro/antiinflammatory cytokines in the intestinal mucosa of patients with active cd, related to steroid response, and identify cellular and molecular factors that may predict this response to therapy. |
2011-10-28 |
2023-08-12 |
Not clear |
| Monika Guratowska, Dorota Pach, Janusz Pach, Barbara Grosze. [The causes and consequences of the cellular death (apoptosis and necrosis) in the course of acute poisoning with carbon monoxide]. Przeglad lekarski. vol 67. issue 8. 2011-10-18. PMID:21387778. |
since the large subpopulation of leukocytes have undergone apoptosis the next step of the studies was to assess the mobilization of progenitor cells (cd 34+) occurring in the peripheral blood after co intoxication. |
2011-10-18 |
2023-08-12 |
human |
| Bo-Rim Yi, Nam-Hee Kang, Kyung-A Hwang, Seung U Kim, Eui-Bae Jeung, Kyung-Chul Cho. Antitumor therapeutic effects of cytosine deaminase and interferon-β against endometrial cancer cells using genetically engineered stem cells in vitro. Anticancer research. vol 31. issue 9. 2011-10-18. PMID:21868529. |
one of these, a cytosine deaminase (cd)/5-fluorocytosine (5-fc) system, is known to induce apoptosis by converting 5-fc, a prodrug, to its metabolically active form, 5-fluorouracil. |
2011-10-18 |
2023-08-12 |
human |
| Binu M Paul, Dianne Vassmer, Aaron Taylor, Lynn Magenheimer, Carol G Carlton, Klaus B Piontek, Gregory G Germino, Gregory B Vanden Heuve. Ectopic expression of Cux1 is associated with reduced p27 expression and increased apoptosis during late stage cyst progression upon inactivation of Pkd1 in collecting ducts. Developmental dynamics : an official publication of the American Association of Anatomists. vol 240. issue 6. 2011-10-03. PMID:21465620. |
taken together, our results suggest that increased cux1 expression associated with apoptosis is a common feature of late stage cyst progression in both the cpk and pkd1(cd) mouse models of pkd. |
2011-10-03 |
2023-08-12 |
mouse |
| Xi-hai Li, Ming-xia Wu, Hong-zhi Ye, Wen-lie Chen, Jiu-mao Lin, Liang-pu Zheng, Xian-xiang Li. Experimental study on the suppression of sodium nitroprussiate-induced chondrocyte apoptosis by Tougu Xiaotong Capsule (透骨消痛胶囊)-containing serum. Chinese journal of integrative medicine. vol 17. issue 6. 2011-09-30. PMID:21660678. |
to study the mechanism of action of tougu xiaotong capsule (透骨消痛胶囊, tgxtc) ex vivo in suppressing chondrocyte (cd) apoptosis induced by sodium nitroprussiate (snp). |
2011-09-30 |
2023-08-12 |
Not clear |
| Smita Khanna, Pramesh C Lakhera, Shashi Khandelwa. Interplay of early biochemical manifestations by cadmium insult in sertoli-germ coculture: an in vitro study. Toxicology. vol 287. issue 1-3. 2011-09-30. PMID:21664405. |
our study shows that cd causes apoptosis in sertoli-germ cells which is governed by oxidative stress. |
2011-09-30 |
2023-08-12 |
rat |
| Wing-Kee Lee, Blazej Torchalski, Naschla Kohistani, Frank Théveno. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport. Toxicological sciences : an official journal of the Society of Toxicology. vol 121. issue 2. 2011-09-19. PMID:21436125. |
cadmium (cd(2+)) damages the kidney proximal tubule (pt) by ceramide-dependent apoptosis and is also a class i carcinogen. |
2011-09-19 |
2023-08-12 |
rat |
| Wing-Kee Lee, Blazej Torchalski, Naschla Kohistani, Frank Théveno. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport. Toxicological sciences : an official journal of the Society of Toxicology. vol 121. issue 2. 2011-09-19. PMID:21436125. |
multidrug resistance p-glycoprotein (mdr1, abcb1) confers resistance to cd(2+) apoptosis, and it has been hypothesized that abcb1 can directly transport cd(2+) as a mode of cellular protection. |
2011-09-19 |
2023-08-12 |
rat |
| Wing-Kee Lee, Blazej Torchalski, Naschla Kohistani, Frank Théveno. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport. Toxicological sciences : an official journal of the Society of Toxicology. vol 121. issue 2. 2011-09-19. PMID:21436125. |
our aim was to investigate the role of abcb1 in cd(2+) transport and ceramide apoptosis. |
2011-09-19 |
2023-08-12 |
rat |
| Wing-Kee Lee, Blazej Torchalski, Naschla Kohistani, Frank Théveno. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport. Toxicological sciences : an official journal of the Society of Toxicology. vol 121. issue 2. 2011-09-19. PMID:21436125. |
furthermore, increased abcb1 expression did not augment (109)cd(2+) efflux but attenuated apoptosis by 10-50μm cd(2+) or 5-25μm c(6)-ceramide, which was abolished by psc833 (1μm). |
2011-09-19 |
2023-08-12 |
rat |
| Wing-Kee Lee, Blazej Torchalski, Naschla Kohistani, Frank Théveno. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport. Toxicological sciences : an official journal of the Society of Toxicology. vol 121. issue 2. 2011-09-19. PMID:21436125. |
whereas pharmacological block of sphingomyelin synthase (0.1mm d609) or sphingosine kinase (1μm dimethylsphingosine), which increase the levels of ceramide and its metabolites, augmented cd(2+)-induced apoptosis, cd(2+) apoptosis was significantly decreased not only by prevention of de novo ceramide synthesis (0.1μm fumonisin b(1)) but also by inhibition of glucosylceramide synthase (2μm c(9)dgj). |
2011-09-19 |
2023-08-12 |
rat |
| Wing-Kee Lee, Blazej Torchalski, Naschla Kohistani, Frank Théveno. ABCB1 protects kidney proximal tubule cells against cadmium-induced apoptosis: roles of cadmium and ceramide transport. Toxicological sciences : an official journal of the Society of Toxicology. vol 121. issue 2. 2011-09-19. PMID:21436125. |
we therefore conclude that cd(2+) efflux is not the mechanism behind abcb1-mediated protection from cd(2+) apoptosis. |
2011-09-19 |
2023-08-12 |
rat |
| Nuray Yazihan, Mehtap Kacar Kocak, Ethem Akcil, Onur Erdem, Ahmet Saya. Role of midkine in cadmium-induced liver, heart and kidney damage. Human & experimental toxicology. vol 30. issue 5. 2011-08-29. PMID:20498035. |
cd, which can induce a broad spectrum of biological effects, is a toxic substance and is associated with inflammation and apoptosis. |
2011-08-29 |
2023-08-12 |
rat |
| Nuray Yazihan, Mehtap Kacar Kocak, Ethem Akcil, Onur Erdem, Ahmet Saya. Role of midkine in cadmium-induced liver, heart and kidney damage. Human & experimental toxicology. vol 30. issue 5. 2011-08-29. PMID:20498035. |
the aim of this study was to determine the possibility of relationship between tissue mk expression levels, tumor necrosis factor α(tnf-α) levels and apoptosis in a chronic cd toxicity model in rats. |
2011-08-29 |
2023-08-12 |
rat |
| Nuray Yazihan, Mehtap Kacar Kocak, Ethem Akcil, Onur Erdem, Ahmet Saya. Role of midkine in cadmium-induced liver, heart and kidney damage. Human & experimental toxicology. vol 30. issue 5. 2011-08-29. PMID:20498035. |
our results showed that chronic cd administration induces inflammation and apoptosis in rat liver, kidney and heart. |
2011-08-29 |
2023-08-12 |
rat |
| Baoshan Xu, Sujuan Chen, Yan Luo, Zi Chen, Lei Liu, Hongyu Zhou, Wenxing Chen, Tao Shen, Xiuzhen Han, Long Chen, Shile Huan. Calcium signaling is involved in cadmium-induced neuronal apoptosis via induction of reactive oxygen species and activation of MAPK/mTOR network. PloS one. vol 6. issue 4. 2011-08-25. PMID:21544200. |
recently we have demonstrated that cd induces neuronal apoptosis in part by activation of the mitogen-activated protein kineses (mapk) and mammalian target of rapamycin (mtor) pathways. |
2011-08-25 |
2023-08-12 |
Not clear |