| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wanyuan Chen, Weimin Fan, Guoqing Ru, Fang Huang, Xiaming Lu, Xin Zhang, Xiaozhou Mou, Shibing Wan. Gemcitabine combined with an engineered oncolytic vaccinia virus exhibits a synergistic suppressive effect on the tumor growth of pancreatic cancer. Oncology reports. vol 41. issue 1. 2019-01-22. PMID:30365143. |
the expression of smac was evaluated by western blot analysis and quantitative polymerase chain reaction, ovv‑smac cytotoxicity by mtt assay, and apoptosis by flow cytometry and western blot analysis. |
2019-01-22 |
2023-08-13 |
Not clear |
| Yifeng Xu, Xu Qiang, Lijun Xing, Hong Wang, Juan Zhang, Fang Zhang, Bilgen Caliskan, Min Wang, Zheng Qi. A fusion antitumor peptide regulates proliferation and apoptosis of endothelial cells. Amino acids. vol 50. issue 8. 2019-01-21. PMID:29796930. |
using western blot, it was indicated that p2 induced the cleavage of caspase-3, the hallmark protease of apoptosis. |
2019-01-21 |
2023-08-13 |
Not clear |
| Duo Wu, Ke Qiao, Meng Feng, Yongfeng Fu, Junlong Cai, Yihong Deng, Hiroshi Tachibana, Xunjia Chen. Apoptosis of Acanthamoeba castellanii Trophozoites Induced by Oleic Acid. The Journal of eukaryotic microbiology. vol 65. issue 2. 2019-01-15. PMID:28787535. |
quantitative pcr and dot blot analysis showed increased levels of metacaspase and interleukin-1β converting enzyme, which is also an indication of apoptosis. |
2019-01-15 |
2023-08-13 |
human |
| Shuxian Xia, Yinglei Miao, Side Li. Withaferin A induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cells. Biochemical and biophysical research communications. vol 503. issue 4. 2019-01-15. PMID:29966656. |
we performed the flow cytometry and western blot to evaluate the withaferin a induced apoptosis and cell cycle arrest in human colon cancer cells. |
2019-01-15 |
2023-08-13 |
human |
| Ni Qin, Shiyin Lu, Ning Chen, Chunxia Chen, Qiuqiao Xie, Xiaojie Wei, Fangxing Ye, Junhui He, Yuchun Li, Lixiu Chen, Luhui Jiang, Xiaoqi Lu, Yuchan Yuan, Jian Li, Yang Jiao, Renbin Huan. Yulangsan polysaccharide inhibits 4T1 breast cancer cell proliferation and induces apoptosis in vitro and in vivo. International journal of biological macromolecules. vol 121. 2019-01-15. PMID:30340007. |
in this study, breast cancer cell 4t1 viability and apoptosis were assessed by cck-8 and flow cytometry, relative quantitative real-time pcr and western blot after treated with drug-serum of ylsps. |
2019-01-15 |
2023-08-13 |
mouse |
| Hongzhi Du, Yue Huang, Xiaoying Hou, Xingping Quan, Jingwei Jiang, Xiaohui Wei, Yang Liu, Hongyang Li, Puhai Wang, Meixiao Zhan, Xun Ai, Ligong Lu, Shengtao Yuan, Li Su. Two novel camptothecin derivatives inhibit colorectal cancer proliferation via induction of cell cycle arrest and apoptosis in vitro and in vivo. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. vol 123. 2019-01-14. PMID:30118848. |
furthermore, the induction of cell cycle arrest and apoptosis was explored through karyomorphology, flow cytometry (fcm) and western blot analysis. |
2019-01-14 |
2023-08-13 |
Not clear |
| Phil Jun Lee, Hye-Jin Park, Namki Cho, Hong Pyo Ki. 3,5-Diethoxy-3'-Hydroxyresveratrol (DEHR) Ameliorates Liver Fibrosis via Caveolin-1 Activation in Hepatic Stellate Cells and in a Mouse Model of Bile Duct Ligation Injury. Molecules (Basel, Switzerland). vol 23. issue 11. 2019-01-14. PMID:30384491. |
flow cytometry and western blot analyses showed that dehr induces apoptosis through the upregulation of cleaved caspase-3 and poly (adp-ribose) polymerase expression and reduction in the level of an anti-apoptotic protein b-cell lymphoma 2 (bcl2). |
2019-01-14 |
2023-08-13 |
mouse |
| Phil Jun Lee, Hye-Jin Park, Namki Cho, Hong Pyo Ki. 3,5-Diethoxy-3'-Hydroxyresveratrol (DEHR) Ameliorates Liver Fibrosis via Caveolin-1 Activation in Hepatic Stellate Cells and in a Mouse Model of Bile Duct Ligation Injury. Molecules (Basel, Switzerland). vol 23. issue 11. 2019-01-14. PMID:30384491. |
as caveolin-1 (cav1), a competitive inhibitor of heme oxygenase 1 (ho-1), is related to apoptotic proteins in hepatic cells, we focused on the role of cav1 in dehr-induced apoptosis in hscs through western blot analyses. |
2019-01-14 |
2023-08-13 |
mouse |
| Quanxi Wang, Mengxi Liu, Yuan Chen, Lihui Xu, Baocheng Wu, Yijan Wu, Yifan Huang, Wei-Ru Huang, Hung-Jen Li. Muscovy duck reovirus p10.8 protein induces ER stress and apoptosis through the Bip/IRE1/XBP1 pathway. Veterinary microbiology. vol 228. 2019-01-14. PMID:30593373. |
to investigate the mechanism underlying the mdrv p10.8-induced er stress and apoptosis, western blot, sirna, and co-immunoprecipitation (co-ip) assays were performed. |
2019-01-14 |
2023-08-13 |
Not clear |
| Zhiwei Zhong, Fan Zhou, Dong Wang, Mingming Wu, Weimin Zhou, Yeqing Zou, Jie Li, Linquan Wu, Xiangbao Yi. Expression of KLF9 in pancreatic cancer and its effects on the invasion, migration, apoptosis, cell cycle distribution, and proliferation of pancreatic cancer cell lines. Oncology reports. vol 40. issue 6. 2019-01-11. PMID:30542730. |
by conducting western blot analyses, we evaluated the expression of relative target proteins (involved in invasion, migration, apoptosis, and cell cycle distribution. |
2019-01-11 |
2023-08-13 |
human |
| Yuanyuan Zheng, Li Lv, Longda Yi, Rui Wu, Rong Xiao, Jihong Wan. rLj-RGD3 Suppresses the Growth of HeyA8 Cells in Nude Mice. Molecules (Basel, Switzerland). vol 22. issue 12. 2019-01-10. PMID:29244724. |
based on the h&e, hoechst 33258 and tunel staining assays, as well as western blot analysis, rlj-rgd3 reduced the weight and volume of the solid tumors, probably by disturbing the tissue structure, inducing apoptosis and suppressing the fak/pi3k/akt pathway. |
2019-01-10 |
2023-08-13 |
mouse |
| Xiong Zhang, Qi Ni, Ying Wang, Hongwei Fan, Yingbin L. Synergistic Anticancer Effects of Formononetin and Temozolomide on Glioma C6 Cells. Biological & pharmaceutical bulletin. vol 41. issue 8. 2019-01-09. PMID:29848900. |
the expression of proteins related to apoptosis and migration were detected by western blot. |
2019-01-09 |
2023-08-13 |
human |
| Dal Kim, Woong Park, Sik Lee, Won Kim, Sung Kwang Park, Kyung Pyo Kan. Absence of Sirt3 aggravates cisplatin nephrotoxicity via enhanced renal tubular apoptosis and inflammation. Molecular medicine reports. vol 18. issue 4. 2019-01-09. PMID:30106119. |
tubular apoptosis, cell adhesion molecule expression, and inflammatory cells were evaluated by immunohistochemistry and western blot analysis. |
2019-01-09 |
2023-08-13 |
mouse |
| Xiaohui Ye, Lingling He, Jiali Ma, Yufeng Li, Manka Zhang, Junru Yang, Jian Zhang, Fan Xiao, Hongshan We. Downregulation of Glt25d1 aggravates carbon tetrachloride‑induced acute hepatic injury through activation of the TGF‑β1/Smad2 signaling pathway. Molecular medicine reports. vol 18. issue 4. 2019-01-09. PMID:30132521. |
furthermore, western blot analyses were performed, and the results demonstrated that the protein levels of cleaved caspase‑3 and ‑9 were also markedly increased in the glt25d1+/‑ liver, indicating that hepatocyte apoptosis was induced. |
2019-01-09 |
2023-08-13 |
mouse |
| Paltan Laha, Umasankar De, Falguni Chandra, Niranjan Dehury, Sadhika Khullar, Hyung Sik Kim, Srikanta Patr. Alkyl chain-modified cyclometalated iridium complexes as tunable anticancer and imaging agents. Dalton transactions (Cambridge, England : 2003). vol 47. issue 44. 2019-01-08. PMID:30358775. |
the light microscopy images and western blot analysis reveal that complex [4]+ induced combined apoptosis and paraptosis. |
2019-01-08 |
2023-08-13 |
human |
| Wei Liu, Zi-Qiang Luo, Lu Ren, Mei Sun, Ju-Qin Yao, Jing-Xia Wang, Zun Wang, Si-Yuan Tan. [ERα36 is involved in the proliferation promotion and anti-apoptosis effects of icaritin on MG63 cells]. Sheng li xue bao : [Acta physiologica Sinica]. vol 70. issue 5. 2019-01-08. PMID:30377685. |
cell proliferation was detected by cck-8, the apoptosis was detected by flow cytometry, and the activation of erk and akt signaling pathways was detected by western blot. |
2019-01-08 |
2023-08-13 |
human |
| Jieyun You, Jian Wu, Qi Zhang, Yong Ye, Shijun Wang, Jiayuan Huang, Haibo Liu, Xiaoyan Wang, Weijing Zhang, Liping Bu, Jiming Li, Li Lin, Junbo Ge, Yunzeng Zo. Differential cardiac hypertrophy and signaling pathways in pressure versus volume overload. American journal of physiology. Heart and circulatory physiology. vol 314. issue 3. 2019-01-07. PMID:29196344. |
signaling pathways related to hypertrophy, fibrosis, angiogenesis, and apoptosis were studied by histological analysis, rt-pcr, and western blot analysis. |
2019-01-07 |
2023-08-13 |
mouse |
| Ruey-Ho Kao, Gi-Ming Lai, Jyh-Ming Chow, Chien-Huang Liao, Yu-Mei Zheng, Wei-Lun Tsai, Simon Hsia, I-Chun Lai, Hsin-Lun Lee, Shuang-En Chuang, Jacqueline Whang-Peng, Chih-Jung Ya. Opposite Regulation of CHOP and GRP78 and Synergistic Apoptosis Induction by Selenium Yeast and Fish Oil via AMPK Activation in Lung Adenocarcinoma Cells. Nutrients. vol 10. issue 10. 2019-01-02. PMID:30297634. |
by sulforhodamine b staining, western blot and flow cytometric assays, we found a synergism between sy and fo in growth inhibition and apoptosis induction of ladc cells. |
2019-01-02 |
2023-08-13 |
Not clear |
| Moussa Ide Nasser, Tingyu Han, Salah Adlat, Yuxin Tian, Nan Jian. Inhibitory effects of Schisandrin B on human prostate cancer cells. Oncology reports. vol 41. issue 1. 2018-12-28. PMID:30320364. |
as indicated by the results of flow cytometric and western blot analysis, sch b could inhibit prostate cancer cell proliferation and promote du145 and lncap cell apoptosis and s‑phase cell arrest. |
2018-12-28 |
2023-08-13 |
human |
| Moussa Ide Nasser, Tingyu Han, Salah Adlat, Yuxin Tian, Nan Jian. Inhibitory effects of Schisandrin B on human prostate cancer cells. Oncology reports. vol 41. issue 1. 2018-12-28. PMID:30320364. |
moreover, real‑time pcr, flow cytometry and western blot result revealed that the cell apoptosis process induced by sch b in lncap cells was associated with its capacity to generate oxidative stress, its inhibition of androgen receptor and the phosphorylation of pi3k/akt and sta3/jak2. |
2018-12-28 |
2023-08-13 |
human |