| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xinrui Zhao, Lidong Liu, Rui Li, Xuan Wei, Wenqing Luan, Peishu Liu, Jing Zha. Hypoxia-Inducible Factor 1-α (HIF-1α) Induces Apoptosis of Human Uterosacral Ligament Fibroblasts Through the Death Receptor and Mitochondrial Pathways. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-02-13. PMID:30504760. |
cell apoptosis and expression of apoptosis-associated proteins and collagen type i alpha 1 (col1a1) were measured by flow cytometry, tunel and western blot, respectively. |
2019-02-13 |
2023-08-13 |
human |
| Zhen Mu, Qing Su. Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway. Molecular medicine reports. vol 18. issue 5. 2019-02-12. PMID:30221692. |
furthermore, ctd treatment could induce a375 cell apoptosis, as detected by annexin v‑fluorescein isothiocyanate/propidium iodide staining and western blot analysis. |
2019-02-12 |
2023-08-13 |
human |
| Yinqiang Xin, Peiling Ben, Qi Wang, Yanyan Zhu, Zhimin Yin, Lan Lu. Theanine, an antitumor promoter, induces apoptosis of tumor cells via the mitochondrial pathway. Molecular medicine reports. vol 18. issue 5. 2019-02-12. PMID:30221698. |
further experiments demonstrated that theanine caused hepg2 cell apoptosis through the mitochondrial pathway, with a loss of membrane potential and the release of apoptosis‑inducing factor, endonuclease g and cytochrome c. western blot analysis and caspase activity detection also revealed that caspase‑9 and caspase‑3 were activated, whereas caspase‑8 remained inactive. |
2019-02-12 |
2023-08-13 |
human |
| Zhengpeng Zeng, Shenghua Sun, Lihua Xi. [Effect of miR-21 on autophagy, proliferation and apoptosis of macrophages induced by cigarette smoke extract]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. vol 43. issue 12. 2019-02-11. PMID:30643042. |
the effects of mir-21 inhibitor on macrophage autophagy, proliferation and apoptosis were detected by western blot, mtt assay and flow cytometry.
results: compared with the control group, the levels of mir-21 and autophagy in the cse group were significantly increased (both p<0.05). |
2019-02-11 |
2023-08-13 |
Not clear |
| Xing-He Wang, Wei Li, Xing-Hui Wang, Mei-Yu Han, Ishfaq Muhammad, Xiu-Ying Zhang, Xiao-Qi Sun, Xiao-Xu Cu. Water-soluble substances of wheat: a potential preventer of aflatoxin B1-induced liver damage in broilers. Poultry science. vol 98. issue 1. 2019-02-06. PMID:30107611. |
the hallmarks of hepatocellular autophagy, apoptosis, and inflammation were measured by western blot and real-time polymerase chain reaction. |
2019-02-06 |
2023-08-13 |
chicken |
| Wenxian Jiang, Rongshen Wang, Di Liu, Min Zuo, Chunzhen Zhao, Tianliang Zhang, Wanzhong L. Protective Effects of Kaempferitrin on Advanced Glycation End Products Induce Mesangial Cell Apoptosis and Oxidative Stress. International journal of molecular sciences. vol 19. issue 11. 2019-02-05. PMID:30373106. |
hoechst 33258 and annexin v and propidium iodide (pi) double staining were performed to observe the apoptosis states in gmcs, whereas apoptosis and protective mechanism in age-induced gmcs were investigated by western blot. |
2019-02-05 |
2023-08-13 |
rat |
| He Zhang, Qingli Shang, Jianbin An, Caixia Wang, Jingxue M. Crocetin inhibits PDGF-BB-induced proliferation and migration of retinal pigment epithelial cells. European journal of pharmacology. vol 842. 2019-02-04. PMID:30395849. |
the levels of main regulatory proteins for apoptosis and the pdgf-bb-induced signaling pathway were determined by western blot analysis. |
2019-02-04 |
2023-08-13 |
Not clear |
| Zefei Wang, Chunzhi Yu, Hong Wan. HOXA5 inhibits the proliferation and induces the apoptosis of cervical cancer cells via regulation of protein kinase B and p27. Oncology reports. vol 41. issue 2. 2019-02-04. PMID:30483748. |
additionally, significant elevation of akt activation measured by western blot analysis abrogated the effect of hoxa5 on caspase‑3 activity, cell apoptosis, proliferation, invasion and cell viability. |
2019-02-04 |
2023-08-13 |
Not clear |
| Beibei Zhang, Jin Xu, Zhe Quan, Miao Qian, Wei Liu, Wanfang Zheng, Fang Yin, Jiru Du, Yuanting Zhi, Ningjing Son. Klotho Protein Protects Human Keratinocytes from UVB-Induced Damage Possibly by Reducing Expression and Nuclear Translocation of NF-κB. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-02-01. PMID:30481165. |
the effects of exposure to uvb radiation on the human keratinocyte hacat cells, including cell growth, apoptosis, and changes of selected biomarkers, were measured by cck-8, flow cytometry, quantitative real-time pcr, and western blot analysis. |
2019-02-01 |
2023-08-13 |
human |
| W Cheng, Y Q Feng, J Ren, D Jing, C Wan. Anti-tumor role of Bacillus subtilis fmbJ-derived fengycin on human colon cancer HT29 cell line. Neoplasma. vol 63. issue 2. 2019-01-28. PMID:26774143. |
western blot analysis showed that after being treated with fengycin, bax, caspase-3, and caspase-6 expressions were increased, however, bcl-2, and cdk4/cyclin d1 expressions were decreased (p<0.05).our study suggested that fengycin may play certain inhibit roles in the development and progression of colon cancer through involving in the cell apoptosis and cell cycle processes by targeting the bax/bcl-2 pathway. |
2019-01-28 |
2023-08-13 |
human |
| Aruo Nan, Yangyang Jia, Xin Li, Meiling Liu, Nan Zhang, Lijian Chen, Ti Yang, Yiqin Xu, Xin Dai, Ying Cheng, Zhenzhong Liu, Yihui Ling, Yiguo Jian. Editor's Highlight: lncRNAL20992 Regulates Apoptotic Proteins to Promote Lead-Induced Neuronal Apoptosis. Toxicological sciences : an official journal of the Society of Toxicology. vol 161. issue 1. 2019-01-28. PMID:29029323. |
silencing lncrnal20992 revealed its significant functions involved in promoting cell apoptosis and inhibiting cell proliferation according to cell-counting kit-8, edu assay, terminal deoxynucleotidyl transferase dutp nick-end labeling, and western blot. |
2019-01-28 |
2023-08-13 |
human |
| Hai Liu, Xuanxuan Wang, Aihua Huang, Huaping Gao, Yikan Sun, Tingting Jiang, Liming Shi, Xianjie Wu, Qinghua Dong, Xiaonan Su. Silencing Artemis Enhances Colorectal Cancer Cell Sensitivity to DNA-Damaging Agents. Oncology research. vol 27. issue 1. 2019-01-28. PMID:29426373. |
induced by dna-damaging agents, delayed dna repair kinetics was found by the γ-h2ax foci assay, and a significantly increased cell apoptosis occurred in the artemis knockdown rko cells through apoptosis detection methods and western blot. |
2019-01-28 |
2023-08-13 |
human |
| Daniel Ngabire, Yeong-Ae Seong, Maheshkumar Prakash Patil, Irvine Niyonizigiye, Yong Bae Seo, Gun-Do Ki. Induction of apoptosis and G1 phase cell cycle arrest by Aster incisus in AGS gastric adenocarcinoma cells. International journal of oncology. vol 53. issue 5. 2019-01-28. PMID:30226597. |
the results of western blot analysis indicated that aie increased the expression of pro-apoptotic proteins, particularly bid, bad, bak, cytochrome c, apoptosis inducing factor (aif), cleaved caspase‑3, -8 and -9 and cleaved poly(adp-ribose) polymerase (parp). |
2019-01-28 |
2023-08-13 |
human |
| Zongmeng Zhang, Jie Chen, Fanghui Chen, Daolun Yu, Rui Li, Chenglong Lv, Haosen Wang, Honglin Li, Jun Li, Yafei Ca. Tauroursodeoxycholic acid alleviates secondary injury in the spinal cord via up-regulation of CIBZ gene. Cell stress & chaperones. vol 23. issue 4. 2019-01-25. PMID:29151236. |
traumatic sci mice were intraperitoneally injected with tudca, and the effects were evaluated based on motor function assessment, histopathology, apoptosis detection, qrt-pcr, and western blot at different time periods. |
2019-01-25 |
2023-08-13 |
mouse |
| Mahmoud Moussa, Meng-Qi Li, Hai-Ying Zheng, Chun-Yan Yang, Sheng-Fei Yan, Nong-Qi Yu, Jia-Xiang Huang, Jiang-Hua Shan. Buffalo oocyte-secreted factors promote cumulus cells apoptosis and the rate of cGMP production but not steroidogenesis. Reproduction in domestic animals = Zuchthygiene. vol 53. issue 6. 2019-01-23. PMID:30058188. |
after 24 hr of ivm, ccs were harvested for evaluation of the relative mrna abundance of the genes encoding gap junction (gja1), glycolysis (pfkp and ldha), apoptosis (caspase-3 and bcl-2) and steroidogenesis (er-β and pgr) by qrt-pcr, and caspase-3 proteins, using western blot. |
2019-01-23 |
2023-08-13 |
Not clear |
| Gan Qiao, Huanli Xu, Cong Li, Xiao Li, Ammad Ahmad Farooqi, Yuming Zhao, Xiaohui Liu, Ming Liu, Dimitrios Stagos, Xiukun Li. Granulin A Synergizes with Cisplatin to Inhibit the Growth of Human Hepatocellular Carcinoma. International journal of molecular sciences. vol 19. issue 10. 2019-01-22. PMID:30301274. |
the combination of the two drugs exhibited a more obvious inhibitory effect on cancer cell apoptosis, as analyzed by the cytometry flow, mitochondrial membrane potential (mmp) and western blot analysis. |
2019-01-22 |
2023-08-13 |
mouse |
| Su-Hyun Nho, Goo Yoon, Ji-Hye Seo, Ha-Na Oh, Seung-Sik Cho, Hangun Kim, Hyun Woo Choi, Jung-Hyun Shim, Jung-Il Cha. Licochalcone H induces the apoptosis of human oral squamous cell carcinoma cells via regulation of matrin 3. Oncology reports. vol 41. issue 1. 2019-01-22. PMID:30320347. |
the present study examined the effects of lch on cell proliferation, induction of apoptosis, and the regulation of matrin 3 (matr3) protein in oral squamous cell carcinoma (oscc) cells by annexin v/propidium iodide (pi) staining and western blot analysis. |
2019-01-22 |
2023-08-13 |
human |
| Zhen Liu, Rui Li, Cheng Jiang, Sha Zhao, Weishan Li, Xiaobo Tan. The neuroprotective effect of lithium chloride on cognitive impairment through glycogen synthase kinase-3β inhibition in intracerebral hemorrhage rats. European journal of pharmacology. vol 840. 2019-01-22. PMID:30336136. |
in this study, male sprague-dawley rats, subjected to intrastriatal blood infusion, were treated with lithium chloride and underwent neurobehavioral test for equivalent injury severity and neurological functional deficits, morris water maze test for cognitive impairment, high performance liquid chromatography analysis for excitotoxic index determination, immunohistochemistry analysis for neuronal apoptosis, and western blot analysis for glycogen synthase kinase-3β activity. |
2019-01-22 |
2023-08-13 |
rat |
| Jeong-Geon Mun, Ji-Ye Kee, Yo-Han Han, Sullim Lee, Seong-Hwan Park, Hee Dong Jeon, Seung-Heon Hon. Galla Rhois water extract inhibits lung metastasis by inducing AMPK‑mediated apoptosis and suppressing metastatic properties of colorectal cancer cells. Oncology reports. vol 41. issue 1. 2019-01-22. PMID:30365120. |
annexin v assay and western blot analysis were performed to elucidate the underlying molecular mechanisms involved in apoptosis. |
2019-01-22 |
2023-08-13 |
Not clear |
| Guanghong Luo, Ruili Feng, Yangyang Sun, Lili Zheng, Yajiang Wang, Yanlu Chen, Tieqiao We. Dendritic cell factor 1 inhibits proliferation and migration and induces apoptosis of neuroblastoma cells by inhibiting the ERK signaling pathway. Oncology reports. vol 41. issue 1. 2019-01-22. PMID:30365123. |
in the present study, we applied immunofluorescence, western blot analysis, flow cytometry and cell tumorigenicity to investigate the dcf1 mechanisms involved in nb apoptosis. |
2019-01-22 |
2023-08-13 |
Not clear |