| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shuyun Ma, Xiaohong Deng, Yang Yang, Qingqing Zhang, Ting Zhou, Zi Li. The lncRNA LINC00675 regulates cell proliferation, migration, and invasion by affecting Wnt/β-catenin signaling in cervical cancer. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-03-18. PMID:30372871. |
linc00675 expression was determined by quantitative real-time polymerase chain reaction; cell proliferation, migration and invasion were determined by cell counting kit-8, transwell migration, and invasion assays, respectively; cell apoptosis was measured by flow cytometry; protein levels were measured by western blot assay. |
2019-03-18 |
2023-08-13 |
Not clear |
| Weichao Zhao, Nan Hu, Dexin Ding, Dingxin Long, Sheng Li, Guangyue Li, Hui Zhan. Developmental toxicity and apoptosis in zebrafish embryos induced by low-dose γ-ray irradiation. Environmental science and pollution research international. vol 26. issue 4. 2019-03-18. PMID:30539402. |
in this paper, the developmental toxicity and apoptosis in zebrafish (danio rerio) embryos induced by 0.01, 0.05, and 0.10-gy γ-ray irradiation were investigated and verified by single cell gel electrophoresis, acridine orange staining, flow cytometry, transmission electron microscopy, digital gene expression sequencing, and western blot analysis. |
2019-03-18 |
2023-08-13 |
zebrafish |
| Elisa Landucci, Irene L Llorente, Berta Anuncibay-Soto, Domenico E Pellegrini-Giampietro, Arsenio Fernández-Lópe. Bicuculline Reverts the Neuroprotective Effects of Meloxicam in an Oxygen and Glucose Deprivation (OGD) Model of Organotypic Hippocampal Slice Cultures. Neuroscience. vol 386. 2019-03-11. PMID:29949743. |
western blot assays were performed to measure levels of cleaved and non-cleaved caspase-3 to quantify apoptosis, while levels of grp78, grp94 and phosphorylated eif2α were used to detect unfolded protein response (upr). |
2019-03-11 |
2023-08-13 |
rat |
| Bo Xu, An-Ming Zhang, Fang Li, Miao Cui, Ji Han, Qin Ca. XZ-1 regulates cell apoptosis of gastric epithelial dysplasia via NF-κB/p53/Ki67 signaling pathway. Bioscience reports. vol 38. issue 3. 2019-03-08. PMID:29588340. |
specimens taken from the pyloric area of the stomachs from rats in each group were subjected to hematoxylin and eosin (h&e) staining for pathological examination, tunel staining for apoptosis detection, and western blot analysis for apoptosis-related proteins. |
2019-03-08 |
2023-08-13 |
rat |
| Chao Liu, Min Jian, Hong Qi, Wei-Zheng Ma. MicroRNA 495 Inhibits Proliferation and Metastasis and Promotes Apoptosis by Targeting Twist1 in Gastric Cancer Cells. Oncology research. vol 27. issue 3. 2019-03-08. PMID:29615148. |
the expressions of mir-495, cell viability, migration, apoptosis, and apoptosis-related factors were examined by qrt-pcr, trypan blue staining, transwell, flow cytometry, and western blot, respectively. |
2019-03-08 |
2023-08-13 |
Not clear |
| Xiaoqi Zhang, Hao Feng, Juan Du, Jing Sun, Dongfang Li, Tomoka Hasegawa, Norio Amizuka, Minqi L. Aspirin promotes apoptosis and inhibits proliferation by blocking G0/G1 into S phase in rheumatoid arthritis fibroblast-like synoviocytes via downregulation of JAK/STAT3 and NF-κB signaling pathway. International journal of molecular medicine. vol 42. issue 6. 2019-03-06. PMID:30221683. |
apoptosis and cell cycle‑associated proteins (bcl‑2, bax, prap1, cyclin d1, p21), as well as the key proteins and their phosphorylation levels of the nf‑κb and jak/stat3 signaling pathways, were detected via western blot analysis. |
2019-03-06 |
2023-08-13 |
Not clear |
| Yanlin Tan, Xingwang Yao, Zhehao Dai, Yunhua Wang, Guohua L. Bone morphogenetic protein 2 alleviated intervertebral disc degeneration through mediating the degradation of ECM and apoptosis of nucleus pulposus cells via the PI3K/Akt pathway. International journal of molecular medicine. vol 43. issue 1. 2019-03-05. PMID:30387830. |
in addition, the levels of phosphorylation of phosphoinositide 3‑kinase (pi3k) and protein kinase b (akt), and the levels of apoptosis‑associated proteins and apoptosis ratio of np cells were also determined by western blot analysis and flow cytometry, respectively. |
2019-03-05 |
2023-08-13 |
human |
| Sheng Zhao, Wei Li, Fan Cheng, Ting Rao, Weimin Yu, Yuan Ruan, Run Yuan, Xiaobing Yao, Jinzhuo Nin. High-pressure carbon dioxide pneumoperitoneum induces oxidative stress and mitochondria-associated apoptotic pathway in rabbit kidneys with severe hydronephrosis. International journal of molecular medicine. vol 43. issue 1. 2019-03-05. PMID:30431064. |
activation of apoptosis was analyzed by western blot analysis of b‑cell lymphoma 2 (bcl‑2), bcl‑2‑associated x protein (bax), cytochrome c (cyt c), caspase‑3 and caspase‑9 levels. |
2019-03-05 |
2023-08-13 |
rabbit |
| Ying Xu, Bing Shu, Ye Tian, Guangxi Wang, Yongjun Wang, Jinwu Wang, Yufeng Don. Oleanolic acid induces osteosarcoma cell apoptosis by inhibition of Notch signaling. Molecular carcinogenesis. vol 57. issue 7. 2019-03-04. PMID:29566282. |
western blot analysis and a mitochondrial membrane potential assay demonstrated that oa functions through the mitochondrial apoptosis pathway. |
2019-03-04 |
2023-08-13 |
human |
| In Hwan Tae, Eun Young Park, Prasanta Dey, Ji Yeon Son, Seok-Yong Lee, Jee H Jung, Saloni Saloni, Mi-Hyun Kim, Hyung Sik Ki. Novel SIRT1 inhibitor 15-deoxy-Δ12,14-prostaglandin J2 and its derivatives exhibit anticancer activity through apoptotic or autophagic cell death pathways in SKOV3 cells. International journal of oncology. vol 53. issue 6. 2019-03-04. PMID:30221742. |
cell cycle arrest, apoptosis and autophagy were determined using flow cytometry or western blot analysis. |
2019-03-04 |
2023-08-13 |
Not clear |
| Zhenlan Du, Haidong Zhang, Qiang Chen, Yongfeng Gao, Baoliang Su. Intranasal Calcitonin Gene-Related Peptide Protects Against Focal Cerebral Ischemic Injury in Rats Through the Wnt/β-Catenin Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-03-04. PMID:30531687. |
cell counting kit-8 assay, colony formation assay, cell cycle assay, apoptosis assay, western blot assay, and top/fop assay were used to investigate the role of cgrp in normal human astrocytes (nha) cells. |
2019-03-04 |
2023-08-13 |
human |
| Yan Ma, Xiaojing Ji. Polydatin Alleviates Radiation-Induced Testes Injury by Scavenging ROS and Inhibiting Apoptosis Pathways. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-03-04. PMID:30539937. |
elisa assay was used to measure the level of inflammatory cytokines, and apoptosis proteins were detected by western blot assay. |
2019-03-04 |
2023-08-13 |
mouse |
| Yanting Chai, Ke Xiang, Yezi Wu, Te Zhang, Ying Liu, Xuewen Liu, Weiguo Zhen, Yuan S. Cucurbitacin B Inhibits the Hippo-YAP Signaling Pathway and Exerts Anticancer Activity in Colorectal Cancer Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2019-03-04. PMID:30566960. |
western blot and real-time pcr were used to investigate the expression of apoptosis and hippo-yap signaling pathway proteins. |
2019-03-04 |
2023-08-13 |
Not clear |
| Jiayu Lin, Qingyan Cai, Bo Liang, Lizhen Wu, Yong Zhuang, Yuanfang He, Wanrong Li. Berberine, a Traditional Chinese Medicine, Reduces Inflammation in Adipose Tissue, Polarizes M2 Macrophages, and Increases Energy Expenditure in Mice Fed a High-Fat Diet. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2019-03-04. PMID:30606998. |
the expression of pro-inflammatory cytokines, apoptosis genes, thermogenic genes (including ucp1), and ire1α, were investigated using immunohistochemistry, western blot, and quantitative reverse transcription polymerase chain reaction (qrt-pcr), in white and brown adipose tissue. |
2019-03-04 |
2023-08-13 |
mouse |
| Lina Shan, Bingjun Bai, Yiming Lv, Binbin Xie, Xuefeng Huang, Hongbo Zh. Lobaplatin suppresses proliferation and peritoneal metastasis of colorectal cancer in a preclinical model. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 108. 2019-02-28. PMID:30243080. |
flow cytometry and western blot analysis confirmed that lobaplatin affected crc cells by inducing apoptosis and modulating the caspase family. |
2019-02-28 |
2023-08-13 |
mouse |
| Chih-Chung Feng, Po-Hsiang Liao, Hsiang-I Tsai, Shiu-Min Cheng, Liang-Yo Yang, Vijaya PadmaViswanadha, Lung-Fa Pan, Ray-Jade Chen, Jeng-Fan Lo, Chih-Yang Huan. Tumorous imaginal disc 1 (TID1) inhibits isoproterenol-induced cardiac hypertrophy and apoptosis by regulating c-terminus of hsc70-interacting protein (CHIP) mediated degradation of Gαs. International journal of medical sciences. vol 15. issue 13. 2019-02-26. PMID:30443176. |
h9c2 cells were pretreated tid1 before iso-induced hypertrophy and apoptosis and then evaluated by ihc, tunel assay, ifc, co-ip, and western blot. |
2019-02-26 |
2023-08-13 |
human |
| Xiao Liang, Shumao Xu, Jun Zhang, Jing Li, Qi She. Cascade Amplifiers of Intracellular Reactive Oxygen Species Based on Mitochondria-Targeted Core-Shell ZnO-TPP@D/H Nanorods for Breast Cancer Therapy. ACS applied materials & interfaces. vol 10. issue 45. 2019-02-25. PMID:30339356. |
western blot demonstrated that zno-tpp@d/h nrs dramatically induced cell apoptosis in 4t1 cells. |
2019-02-25 |
2023-08-13 |
Not clear |
| Dalin Sun, Weihang Dong, Baofang Jin, Guanghui Chen, Bin Cai, Weimin Deng, Yugui Cui, Yihan Ji. Mechanisms of Yangjing Capsule in Leydig Cell Apoptosis and Testosterone Synthesis via Promoting StAR Expression. Biological & pharmaceutical bulletin. vol 41. issue 9. 2019-02-20. PMID:29984732. |
leydig tumor cells (mltc-1) were cultured and treated with yc, and immunofluorescence assay was performed to examine the expression of star; furthermore, luciferase reporter assay was conducted to evaluate the impact of yc on star promoter; next, mltc-1 cells were treated with star small interfering rna (sirna), and flow cytometry was carried out to examine the effect of star sirna on the apoptosis of the cells; furthermore, quantitative (q)rt-pcr and western blot methods was used to determine the expression of star and apoptosis related molecules bcl-2, bax and caspase-3 on both mrna and protein levels in different groups; finally the secretion of testosterone in different groups was examined by radioimmunoassay. |
2019-02-20 |
2023-08-13 |
Not clear |
| Leila Shahriyary, Gholamhossein Riazi, Mohammad Reza Lornejad, Mansoureh Ghezlou, Bahareh Bigdeli, Behdad Delavari, Fatemeh Mamashli, Shayan Abbasi, Jamshid Davoodi, Ali Akbar Sabour. Effect of glycated insulin on the blood-brain barrier permeability: An in vitro study. Archives of biochemistry and biophysics. vol 647. 2019-02-18. PMID:29444458. |
apoptosis induction was determined and confirmed by flow cytometry and western blot analyses, respectively. |
2019-02-18 |
2023-08-13 |
Not clear |
| Fan Zhang, Hui-Zeng Lv, Ji-Ming Liu, Xiao-Yong Ye, Cun-Chuan Wan. UNBS5162 inhibits colon cancer growth via suppression of PI3K/Akt signaling pathway. Medecine sciences : M/S. vol 34 Focus issue F1. 2019-02-13. PMID:30403183. |
in addition, annexin v-fitc/pi assay and western blot analysis were performed to detect whether unbs5162 could induce cell apoptosis. |
2019-02-13 |
2023-08-13 |
Not clear |