| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiaming Chen, Zhian Chen, Sai Cao, Botang Guo, Yilin Chen, Zixin Feng, Jiaqi Wang, Guohu Guo, Xinhua Chen, Xianying Huan. Role of CircRNAs_100395 in Proliferation and Metastases of Liver Cancer. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-14. PMID:31421050. |
cell proliferation, apoptosis, invasion, migration, and epithelial-mesenchymal transition (emt) pathway of circ_100395 upregulated cells were analyzed using a cell counting kit-8 (cck-8), flow cytometry, transwell assay, and western blot analysis. |
2020-02-14 |
2023-08-13 |
Not clear |
| Daorui Qin, Yunman Tang, Xuejun Wang, Yu Mao, Zhichun Fen. Antagonistic Effect of Cuscuta chinensis on a Rat Model with Unilateral Cryptorchidism. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-12. PMID:31493333. |
after 90 days, all the rats were sacrificed and the testicles were separated and weighed, followed by tunel staining to detect germ cell apoptosis, flow cytometry to measure jc-1, ros, and mda, and western blot analysis to evaluate the expression of bax, bcl-2, and cleaved caspase3. |
2020-02-12 |
2023-08-13 |
rat |
| Shuangbin Ji, Rongli Sun, Kai Xu, Zhaodi Man, Jiahui Ji, Yunqiu Pu, Lihong Yin, Juan Zhang, Yuepu P. Prodigiosin induces apoptosis and inhibits autophagy via the extracellular signal-regulated kinase pathway in K562 cells. Toxicology in vitro : an international journal published in association with BIBRA. vol 60. 2020-02-10. PMID:31077745. |
here, we examined whether prodigiosin affected apoptosis and autophagy through the extracellular signal-regulated (erk) signaling pathway in k562 cells, employing cell proliferation, flow cytometry, caspase activity, and western blot analyses. |
2020-02-10 |
2023-08-13 |
Not clear |
| Yi Xin, Xin Huang, Zengbei Li, Wenfei Zhao, Chunlin Wang, Shaobo Wang, Xianyang Yue, Hui Mo, Hongyun L. Versatile Pt NCs-based chemotherapeutic agents significantly induce the apoptosis of cisplatin-resistant non-small cell lung cancer. Biochemical and biophysical research communications. vol 512. issue 2. 2020-02-07. PMID:30885437. |
it was found that our pt ncs-based chemotherapeutic drugs showed its preferable therapeutic effect in cisplatin-resistant nsclc through the results of confocal microscopic images, cell counting kit-8 test, cell apoptosis assay and western blot. |
2020-02-07 |
2023-08-13 |
Not clear |
| Guiyan Chu, Xiaoge Zhou, Yamei Hu, Shengjie Shi, Gongshe Yan. Rev-erbα Inhibits Proliferation and Promotes Apoptosis of Preadipocytes through the Agonist GSK4112. International journal of molecular sciences. vol 20. issue 18. 2020-02-05. PMID:31547330. |
in this study, we used gsk4112 to explore the effects of rev-erbα on preadipocyte proliferation and apoptosis by rt-qpcr, western blot, cell counting kit-8 (cck8) measurement, 5-ethynyl-2'-deoxyuridine (edu) staining, annexin v-fitc/pi staining, and flow cytometry. |
2020-02-05 |
2023-08-13 |
Not clear |
| Jiquan Wang, Yingbing Zhang, Xu Liu, Jizhao Wang, Bin Li, Yongkang Liu, Jiansheng Wan. Alantolactone enhances gemcitabine sensitivity of lung cancer cells through the reactive oxygen species-mediated endoplasmic reticulum stress and Akt/GSK3β pathway. International journal of molecular medicine. vol 44. issue 3. 2020-02-04. PMID:31524219. |
the cell cycle, apoptosis and the level of reactive oxygen species (ros) were assessed by flow cytometry, and the expression of cell cycle‑associated and apoptosis‑associated proteins were determined by western blot analysis. |
2020-02-04 |
2023-08-13 |
Not clear |
| Yongzhe Liu, Li Sun, Yaqun Ma, Biyu Wei, Minglong Gao, Lixin Shan. High glucose and bupivacaine‑induced cytotoxicity is mediated by enhanced apoptosis and impaired autophagy via the PERK‑ATF4‑CHOP and IRE1‑TRAF2 signaling pathways. Molecular medicine reports. vol 20. issue 3. 2020-02-04. PMID:31524237. |
cell viability was measured using a cell counting kit‑8 assay, cell apoptosis was assessed using flow cytometry, and protein expression was determined using western blot analyses. |
2020-02-04 |
2023-08-13 |
human |
| Lili Liu, Likun Wang, Xidong Li, Ping Tian, Hao Xu, Zenglian Li, Enqin Li. Effect of miR-21 on apoptosis in hepatoblastoma cell through activating ASPP2/p38 signaling pathway Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2020-02-04. PMID:31535570. |
rt-pcr, fish, western blot, apoptosis assay, migration, invasion and wound healing assays, caspase activity assay, luciferase reporter assays, and xenografts mouse model were used to determine the effects of mir-21 on hb cell apoptosis. |
2020-02-04 |
2023-08-13 |
mouse |
| Bing Gao, Song Li, Guo L. Long Noncoding RNA (lncRNA) Small Nucleolar RNA Host Gene 5 (SNHG5) Regulates Proliferation, Differentiation, and Apoptosis of K562 Cells in Chronic Myeliod Leukemia. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-01-31. PMID:31506418. |
western blot analysis was performed to detect protein expressions related to cell proliferation, differentiation, and apoptosis. |
2020-01-31 |
2023-08-13 |
human |
| Xiaokang Liu, Yu Li, Qiang Ma, Yanwei Wang, Ai Lin Son. Withaferin-A Inhibits Growth of Drug-Resistant Breast Carcinoma by Inducing Apoptosis and Autophagy, Endogenous Reactive Oxygen Species (ROS) Production, and Inhibition of Cell Migration and Nuclear Factor kappa B (Nf-κB)/Mammalian Target of Rapamycin (m-TOR) Signalling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-01-31. PMID:31512681. |
effects on cell apoptosis were studied by fluorescence microscopy in combination with flow cytometry and western blot analysis. |
2020-01-31 |
2023-08-13 |
mouse |
| Yuan Sui, Guangyao Lin, Yinshi Zheng, Wenqi Huan. LncRNA MAFG-AS1 boosts the proliferation of lung adenocarcinoma cells via regulating miR-744-5p/MAFG axis. European journal of pharmacology. vol 859. 2020-01-28. PMID:31211984. |
proliferation or apoptosis of luad cells were measured by cck-8, edu and caspase-3 activity assays followed by western blot. |
2020-01-28 |
2023-08-13 |
Not clear |
| Jiaxin Zheng, Shoulin Zhang, Huijun Chen, Xiaojun Cai, Chunjian Zhang, Shuhua Li, Yabin Zhou, Jing Shang, Shunyu Liang, Fengzhen Ya. Protosappanin-A and oleanolic acid protect injured podocytes from apoptosis through inhibition of AKT-mTOR signaling. Cell biology international. 2020-01-28. PMID:31441181. |
an in vitro model of podocyte injury was induced by the sc5b-9 complex and assays such as cell viability, apoptosis, immunofluorescence, quantitative real-time polymerase chain reaction, and western blot were performed to further investigate the effects and mechanisms of pra and oa in podocyte injury. |
2020-01-28 |
2023-08-13 |
Not clear |
| Xu Deng, Jiexia Sheng, Hua Liu, Nannan Wang, Cuoji Dai, Zhenguo Wang, Jing Zhang, Jianye Zhao, Erqing Da. Cinobufagin Promotes Cell Cycle Arrest and Apoptosis to Block Human Esophageal Squamous Cell Carcinoma Cells Growth via the p73 Signalling Pathway. Biological & pharmaceutical bulletin. vol 42. issue 9. 2020-01-27. PMID:31474710. |
in addition, the expression of proteins related to cell cycle arrest and apoptosis was assessed by real-time quantitative (q)rt-pcr and western blot. |
2020-01-27 |
2023-08-13 |
human |
| Xiaofang Wang, Xinmin Wang, Le Zhang, Yuqing Zhang, Feiyu Wang, Yang Lu, Wanjiang Zhang, Jiangdong W. Mcl-1 signals pathway inhibitors in mouse peritoneal macrophage apoptosis infected with the Xinjiang strain of International journal of clinical and experimental pathology. vol 10. issue 12. 2020-01-26. PMID:31966560. |
we using tunel, immunohistochemical analysis, elisa, he, rt-pcr and western blot detected macrophages apoptosis, the damage of mice tissues and the expression of apoptosis genes and proteins. |
2020-01-26 |
2023-08-13 |
mouse |
| Daofu Jia, Yanping Niu, Dongling Li, Qingguo Zhan. MicroRNA-223 alleviates lipopolysaccharide-induced PC-12 cells apoptosis and autophagy by targeting RPH1 in spinal cord injury. International journal of clinical and experimental pathology. vol 10. issue 9. 2020-01-26. PMID:31966794. |
pc-12 cells were treated with different concentrations of lps, and then cell viability, apoptosis, apoptosis-related factors and autophagy-related factors were analyzed by cck-8, flow cytometry and western blot. |
2020-01-26 |
2023-08-13 |
Not clear |
| Yongxiang Wang, Chunyan Wan. microRNA-211-3p has a Role in the Effects of Lipopolysaccharide on Endoplasmic Reticulum Stress in Cultured Human Skin Fibroblasts. Medical science monitor basic research. vol 25. 2020-01-24. PMID:31221950. |
protein expression levels of the transcription factors grp78, chop, p-jnk, and the endoplasmic reticulum stress apoptosis proteins, caspase-12 and bcl-2, were determined by western blot. |
2020-01-24 |
2023-08-13 |
human |
| Naoto Sakurai, Yoshihiro Komada, Ryo Hanaki, Mari Morimoto, Takahiro Ito, Daisuke Nakato, Masahiro Hirayam. Role of microRNAs in glucocorticoid‑resistant B‑cell precursor acute lymphoblastic leukemia. Oncology reports. vol 42. issue 2. 2020-01-24. PMID:31233193. |
as determined by rt‑qpcr and western blot analyses, gc treatment upregulated glucocorticoid receptor (gr) protein and bcl‑2‑interacting mediator of cell death (bcl2l11, bim) protein expression, resulting in apoptosis of a gc‑sensitive bcp‑all cell line, but not of a gc‑resistant bcp‑all cell line as shown by flow cytometry. |
2020-01-24 |
2023-08-13 |
Not clear |
| Jingyun Jin, Yonggang Guo, Yang Liu, Zhenguo Wang, Xiaosa Yang, Shengkai Su. Synergistic antitumor effect of BRMS1 and sorafenib via inhibition of the PI3K/AKT/mTOR/ERK signaling pathway. Oncology reports. vol 42. issue 3. 2020-01-24. PMID:31233204. |
in addition, expression of inflammatory response‑related genes was increased, while secretion of angiogenesis‑related molecules was decreased, and apoptosis was also activated after sorafenib treatment using qpcr method, and it was further demonstrated that this effect was mediated by inhibition of the pi3k/akt/mtor/erk signaling pathway using western blot analysis. |
2020-01-24 |
2023-08-13 |
human |
| Xingbin Dai, Bangyun Ma, Pengjun Jiang, Zuqiong Xu, Xiangtu Kong, Xuemei Su. Tenacigenin B Has Anti-Tumor Effect in Lymphoma by In Vitro and In Vivo Study. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-01-24. PMID:31473762. |
measuring the cell proliferation of difference groups was done by mtt assay; cell apoptosis and cell cycle of difference groups were evaluated by flow cytometer; relative mrna expression was evaluated by real-time polymerase chain reaction (rt-pcr), and relative protein expressions were measured by western blot assay in an in vitro study. |
2020-01-24 |
2023-08-13 |
mouse |
| Elena Marchesi, Nicola Chinaglia, Massimo L Capobianco, Paolo Marchetti, Tzu-En Huang, Hao-Cheng Weng, Jih-Hwa Guh, Lih-Ching Hsu, Daniela Perrone, Maria Luisa Navacchi. Dihydroartemisinin-Bile Acid Hybridization as an Effective Approach to Enhance Dihydroartemisinin Anticancer Activity. ChemMedChem. vol 14. issue 7. 2020-01-22. PMID:30724466. |
strong evidence that an ursodeoxycholic acid hybrid induced apoptosis was obtained by flow cytometric analysis and western blot analysis. |
2020-01-22 |
2023-08-13 |
Not clear |