| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiangxia Zheng, Xian Cheng, Shichen Xu, Li Zhang, Jie Pan, Huixin Yu, Jiandong Bao, Rongrong L. Diallyl trisulfide induces G2/M cell-cycle arrest and apoptosis in anaplastic thyroid carcinoma 8505C cells. Food & function. vol 10. issue 11. 2020-04-16. PMID:31617531. |
further results showed that dats induced mitochondrial apoptosis in 8505c cells, evidenced by hoechst/pi double staining, pi-annexin v assay and western blot. |
2020-04-16 |
2023-08-13 |
Not clear |
| Ying Li, Chenguang Wang, Yang Liu, Jiaxin You, Guanfang S. Autophagy, lysosome dysfunction and mTOR inhibition in MNU-induced photoreceptor cell damage. Tissue & cell. vol 61. 2020-04-16. PMID:31759414. |
we also measured the expression of some proteins related to autophagy, apoptosis and lysosomal degradation by western blot and immunofluorescence assays. |
2020-04-16 |
2023-08-13 |
Not clear |
| Wei Wang, Yang Wang, Mingxing Liu, Yifan Zhang, Tao Yang, Dongsheng Li, Yinpeng Huang, Qing Li, Guang Bai, Linlin Sh. Betulinic acid induces apoptosis and suppresses metastasis in hepatocellular carcinoma cell lines in vitro and in vivo. Journal of cellular and molecular medicine. vol 23. issue 1. 2020-04-15. PMID:30417527. |
moreover, western blot analysis showed that ba-induced apoptosis associated with increasing of pro-apoptotic protein bax and cleaved caspase-3 and decreasing of anti-apoptotic protein bcl-2. |
2020-04-15 |
2023-08-13 |
mouse |
| Na Lv, Chunqing Li, Xin Liu, Caihui Qi, Zhenqing Wan. miR-34b Alleviates High Glucose-Induced Inflammation and Apoptosis in Human HK-2 Cells via IL-6R/JAK2/STAT3 Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-04-15. PMID:31665127. |
material and methods expression of mir-34b, il-6r, and other key factors of inflammation, apoptosis (tnf-alpha, il-1ß, il-6, caspase-3) in high glucose (hg)-induced hk-2 cells were measured by real-time pcr, western blot, and flow cytometric cell apoptosis assays. |
2020-04-15 |
2023-08-13 |
human |
| Juan Cao, Xiang-Sheng Li. Circular RNA 0060428 sponges miR-375 to promote osteosarcoma cell proliferation by upregulating the expression of RPBJ. Gene. vol 740. 2020-04-15. PMID:32130980. |
western blot analyses indicated that circ-0060428 regulated the expression of apoptosis related proteins (bax, bcl-2, and cleaved-caspase-3) by upregulating rpbj expression in osteosarcoma cells. |
2020-04-15 |
2023-08-13 |
Not clear |
| Zi-Jian Yang, Jun-Yao Huang, Ye-Fei Gao, Jun-Yao Huang, Wen-Ji Huang, Jun-Yao Huang, Shi-Lei Xu, Jun-Yao Huang, Jing-Jing Jin, Jun-Yao Huang, Ye-Dong Wan, Jun-Yao Huang, Ming Yan, Jun-Yao Huang, Hong-Jiao Mao, Jun-Yao Huang, Yun Zhang, Jun-Yao Huan. [Effects of bergapten on damages of osteocytes MLO-Y4 induced by TCP wear particles and its mechanism]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 35. issue 6. 2020-04-14. PMID:32239867. |
mtt assay and calcein-am staining were used to determine the viability of mlo-y4 cells; hoechst 33342 staining and the flow cytometry were applied to detect the apoptosis of mlo-y4; real-time pcr was performed to examine the mrna levels of dentin matrix protein1 (dmp-1), sclerostin (sost) and fibroblast growth factor23 (fgf23); western blot was performed to examine protein expressions of glucose-regulated protein 78 (grp78), protein kinase r-like er kinase (perk) phospho-perk (p-perk), eukaryotic initiation factor 2α (eif2α), phospho-eif2α (p-eif2α), activating transcription factor 4 (aft4), c/ebp homologous protein (chop) and caspase-3 in mlo-y4 cells. |
2020-04-14 |
2023-08-13 |
Not clear |
| Mei-Fang Xia. [Effect of polyphyllin D on proliferation and apoptosis of human pancreatic cancer cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 6. 2020-04-14. PMID:32281356. |
the apoptosis was detected by annexin v-fitc/pi staining, and western blot was used to detect the protein expressions of cytochrome c(cyto c), bax, bcl-2, cleaved caspase-3 and cleaved caspase-9. |
2020-04-14 |
2023-08-13 |
human |
| Mei-Fang Xia. [Effect of polyphyllin D on proliferation and apoptosis of human pancreatic cancer cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 6. 2020-04-14. PMID:32281356. |
flow cytometry results showed that polyphyllin d could block the cells in s and g_2/m phase in a concentration manner, the mmp of the cells was significantly reduced, and the apoptosis rate increased with the concentration of polyphyllin d. western blot results showed that polyphyllin d could concentration-dependently up-regulate the protein expression levels of bax, cyto c, cleaved caspase-3 and cleaved caspase-9, and down-regulate the protein expression level of bcl-2. |
2020-04-14 |
2023-08-13 |
human |
| Xueyuan Yu, Xiangyu Liu, Rui Wang, Lu Wan. Long non-coding RNA NEAT1 promotes the progression of hemangioma via the miR-361-5p/VEGFA pathway. Biochemical and biophysical research communications. vol 512. issue 4. 2020-04-09. PMID:30928097. |
the role and mechanism of neat1 on the proliferation, migration and apoptosis of hemangioma endothelial cells (hemecs) were analyzed by cell counting kit (cck)-8, transwell, flow cytometry, caspase-3 activity, dual-luciferase assay, rna immunoprecipitation, biotin-labeled mir-361-5p pulldown assay and western blot by gain- and loss-of-functions. |
2020-04-09 |
2023-08-13 |
Not clear |
| Wei Zhang, Yangyang Zhang, Hengbing Zhang, Qian Zhao, Zheng Liu, Yawei X. USP49 inhibits ischemia-reperfusion-induced cell viability suppression and apoptosis in human AC16 cardiomyocytes through DUSP1-JNK1/2 signaling. Journal of cellular physiology. vol 234. issue 5. 2020-04-08. PMID:30246457. |
cell viability, apoptosis, the bax, bcl-2, and dusp1 expression, and the activity of mapks in ac16 cardiomyocytes following indicated treatment was measured by cck-8, flow cytometry, and western blot analysis. |
2020-04-08 |
2023-08-13 |
human |
| Wei Zhang, Yangyang Zhang, Hengbing Zhang, Qian Zhao, Zheng Liu, Yawei X. USP49 inhibits ischemia-reperfusion-induced cell viability suppression and apoptosis in human AC16 cardiomyocytes through DUSP1-JNK1/2 signaling. Journal of cellular physiology. vol 234. issue 5. 2020-04-08. PMID:30246457. |
the effect of usp49 on apoptosis and jnk activity in rat cardiomyocytes following i/r injury was also measured by tunel and western blot analysis. |
2020-04-08 |
2023-08-13 |
human |
| Yafan Gong, Jie Yang, Jingzeng Cai, Qi Liu, Jun Min Zhang, Ziwei Zhan. Effect of Gpx3 gene silencing by siRNA on apoptosis and autophagy in chicken cardiomyocytes. Journal of cellular physiology. vol 234. issue 6. 2020-04-07. PMID:30515791. |
quantitative real-time pcr and western blot analysis are performed to detect the expression of apoptosis and autophagy-related genes. |
2020-04-07 |
2023-08-13 |
chicken |
| Yongyun Luo, Yaqin He, Xiaoping Ye, Jianjun Song, Qi Wang, Yukui Li, Xiaoliang Xi. High Expression of Long Noncoding RNA HOTAIRM1 is Associated with the Proliferation and Migration in Pancreatic Ductal Adenocarcinoma. Pathology oncology research : POR. vol 25. issue 4. 2020-04-02. PMID:30613920. |
western blot assay was applied to determine the expression changes of cell cycle, apoptosis, and migration-related genes before and after downregulating hotairm1. |
2020-04-02 |
2023-08-13 |
human |
| Xiaoguang Wu, Xiaohui Zheng, Jing Cheng, Kai Zhang, Cao M. LncRNA TUG1 regulates proliferation and apoptosis by regulating miR-148b/IGF2 axis in ox-LDL-stimulated VSMC and HUVEC. Life sciences. vol 243. 2020-04-02. PMID:31926240. |
cell proliferation and apoptosis were detected by cck-8, flow cytometry and western blot. |
2020-04-02 |
2023-08-13 |
human |
| Genquan Yue, Caixia Chen, Ligang Bai, Guoqiang Wang, Yong Huang, Yunbin Wang, Hongwei Cui, Yunfeng Xia. Knockdown of long noncoding RNA DLEU1 suppresses the progression of renal cell carcinoma by downregulating the Akt pathway. Molecular medicine reports. vol 20. issue 5. 2020-03-31. PMID:31702026. |
the protein expression levels of factors associated with apoptosis and epithelial‑mesenchymal transition (emt) were examined by western blot. |
2020-03-31 |
2023-08-13 |
Not clear |
| Haobin Zhao, Xiaoguang Xu, Shuzhen Lei, Dongyan Shao, Chunmei Jiang, Junling Shi, Yawen Zhang, Li Liu, Shuzhen Lei, Hui Sun, Qingsheng Huan. Iturin A-like lipopeptides from Bacillus subtilis trigger apoptosis, paraptosis, and autophagy in Caco-2 cells. Journal of cellular physiology. vol 234. issue 5. 2020-03-30. PMID:30238995. |
a western blot analysis showed that the lipopeptides induced apoptosis in caco-2 cells via a mitochondrial-dependent pathway, as indicated by upregulated expression of the apoptotic genes bax and bad and downregulated expression of the antiapoptotic gene bcl-2. |
2020-03-30 |
2023-08-13 |
human |
| Yuan-Yuan Yang, Dao-Jing Gong, Jian-Jian Zhang, Xiu-Heng Liu, Lei Wan. Diabetes aggravates renal ischemia-reperfusion injury by repressing mitochondrial function and PINK1/Parkin-mediated mitophagy. American journal of physiology. Renal physiology. vol 317. issue 4. 2020-03-30. PMID:31390235. |
renal pathology, function, and apoptosis were evaluated by hematoxylin and eosin staining, transmission electron microscopy, and western blot analysis. |
2020-03-30 |
2023-08-13 |
rat |
| Yuan-Yuan Yang, Dao-Jing Gong, Jian-Jian Zhang, Xiu-Heng Liu, Lei Wan. Diabetes aggravates renal ischemia-reperfusion injury by repressing mitochondrial function and PINK1/Parkin-mediated mitophagy. American journal of physiology. Renal physiology. vol 317. issue 4. 2020-03-30. PMID:31390235. |
also, cells in the high glucose + h/r group exhibited more apoptosis compared with the normal glucose + h/r group, as assessed by flow cytometry, tunel staining, and western blot analysis. |
2020-03-30 |
2023-08-13 |
rat |
| Hyung Jung Oh, Hyewon Oh, Bo Young Nam, Je Sung You, Dong-Ryeol Ryu, Shin-Wook Kang, Yong Eun Chun. The protective effect of klotho against contrast-associated acute kidney injury via the antioxidative effect. American journal of physiology. Renal physiology. vol 317. issue 4. 2020-03-30. PMID:31411071. |
rt-pcr and western blot analysis were performed to assess propidium iodide klotho expression, and bax-to-bcl-2 and apoptosis ratios were evaluated with annexin v/hoechst 33342 staining. |
2020-03-30 |
2023-08-13 |
mouse |
| Xiaojia Zhou, Yunchun Kuang, Simin Liang, Li Wan. Metformin inhibits cell proliferation in SKM-1 cells via AMPK-mediated cell cycle arrest. Journal of pharmacological sciences. vol 141. issue 4. 2020-03-27. PMID:31744691. |
apoptosis and cell cycle phases were detected by flow cytometry, while cell cycle related proteins and ampk were tested by western blot. |
2020-03-27 |
2023-08-13 |
Not clear |