| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ling Li, Min Liu, Lianman He, Shanshan Wang, Shuxian Cu. Baicalin relieves TNF-α-evoked injury in human aortic endothelial cells by up-regulation of miR-145. Phytotherapy research : PTR. vol 34. issue 4. 2020-07-27. PMID:31793706. |
cell viability, apoptosis, and expressions of crucial proteins were respectively evaluated using cell counting kit-8 assay, flow cytometry, and western blot. |
2020-07-27 |
2023-08-13 |
human |
| Qi Wei, Huan-Yu Zhou, Xiao-Dong Shi, Hong-Yan Cao, Ling Qi. Long Noncoding RNA NEAT1 Promotes Myocardiocyte Apoptosis and Suppresses Proliferation Through Regulation of miR-129-5p. Journal of cardiovascular pharmacology. vol 74. issue 6. 2020-07-27. PMID:31815867. |
collagen deposition and apoptosis were evaluated by western blot detection of collagen and apoptotic proteins, including capase3, bax, and bcl2. |
2020-07-27 |
2023-08-13 |
Not clear |
| Mingming Ma, Bing Li, Mingliang Zhang, Lei Zhou, Fuhua Yang, Feifei Ma, Hui Shao, Qiutang Li, Xiaorong Li, Xiaomin Zhan. Therapeutic effects of mesenchymal stem cell-derived exosomes on retinal detachment. Experimental eye research. vol 191. 2020-07-24. PMID:31866431. |
the retinal expression levels of inflammatory cytokines tnf-α, il-1β, and mcp-1 were detected by rt-pcr, the autophagy-related protein 5 (atg5) and microtubule-associated protein 1 light chain 3 beta (lc3) were detected by western blot, and apoptosis was examined using tunel assays at 3 days following rd. |
2020-07-24 |
2023-08-13 |
rat |
| You-Cheng Hseu, Hsin-Ju Cho, Yugandhar Vudhya Gowrisankar, Varadharajan Thiyagarajan, Xuan-Zao Chen, Kai-Yuan Lin, Hui-Chi Huang, Hsin-Ling Yan. Kalantuboside B induced apoptosis and cytoprotective autophagy in human melanoma A2058 cells: An in vitro and in vivo study. Free radical biology & medicine. vol 143. 2020-07-22. PMID:31442557. |
a western blot indicated cell-cycle inhibition (cyclin a reduction), apoptosis induction (parp cleavage and bcl-2 inhibition), and cytoprotective autophagy (lc3-ii upregulation and p53 downregulation) in kb-treated a2058-xenografted mice. |
2020-07-22 |
2023-08-13 |
mouse |
| Somaiah Chinnapaka, Guoxing Zheng, Aoshuang Chen, Gnanasekar Munirathina. Nitro aspirin (NCX4040) induces apoptosis in PC3 metastatic prostate cancer cells via hydrogen peroxide (H Free radical biology & medicine. vol 143. 2020-07-22. PMID:31446057. |
western blot analysis revealed that significant down regulation of key anti-apoptotic markers such as cellular inhibitor of apoptosis protein-1 (ciap1), x-linked inhibitor of apoptosis (xiap), survivin, and cellular-myc (c-myc). |
2020-07-22 |
2023-08-13 |
Not clear |
| Qiong Wang, Chenming Zou, Lingying Wang, Xueqin Gao, Jindan Wu, Songwei Tan, Gang W. Doxorubicin and adjudin co-loaded pH-sensitive nanoparticles for the treatment of drug-resistant cancer. Acta biomaterialia. vol 94. 2020-07-21. PMID:31141733. |
western blot and polymerase chain reaction analyses showed that inhibition of p-glycoprotein and x-linked inhibitor of apoptosis protein expression may underlie inhibition of tumor resistance mediated by nps. |
2020-07-21 |
2023-08-13 |
Not clear |
| Yuhang Zhou, Xiang Fu, Yanqing Guan, Mengting Gong, Kan He, Bei Huan. 1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway. Biochemical pharmacology. vol 172. 2020-07-20. PMID:31836387. |
eukaryotic transcriptome sequencing and western blot analysis demonstrated that 1,3-dcqa binds to 14-3-3τ to prevent breast cancer proliferation and metastasis via jak/pi3k/akt and raf/erk pathway, which promote il6 and csf3 expression raised by creb (crebbp, creb5) and induced cell apoptosis via bad/bax/caspase 9 signaling pathway. |
2020-07-20 |
2023-08-13 |
human |
| Xiangyu Liu, Shengli Wang, Guoan Zha. Baicalin relieves lipopolysaccharide-evoked inflammatory injury through regulation of miR-21 in H9c2 cells. Phytotherapy research : PTR. vol 34. issue 5. 2020-07-20. PMID:31984561. |
in this investigation, we attempted to investigate the influences of baicalin on lipopolysaccharide (lps)-evoked h9c2 cells.cells viability, apoptosis, and expressions of apoptosis-associated proteins were, respectively, measured utilizing cck-8 assay, flow cytometry and western blot. |
2020-07-20 |
2023-08-13 |
Not clear |
| Zohreh Abdolvahabi, Mitra Nourbakhsh, Saman Hosseinkhani, Zahra Hesari, Mohsen Alipour, Meisam Jafarzadeh, Seyedeh Sara Ghorbanhosseini, Parvaneh Seiri, Zeynab Yousefi, Sahar Yarahmadi, Pegah Golpou. MicroRNA-590-3P suppresses cell survival and triggers breast cancer cell apoptosis via targeting sirtuin-1 and deacetylation of p53. Journal of cellular biochemistry. vol 120. issue 6. 2020-07-17. PMID:30520099. |
the effects of mir-590-3p upregulation on the acetylation of p53 as well as cell viability and apoptosis were assessed by western blot analysis, wst-1 assay, and flow cytometry, respectively. |
2020-07-17 |
2023-08-13 |
human |
| Yuning Lin, Yongxin Chen, Shengshan Wang, Jing Ma, Yue Peng, Xianling Yuan, Beibei Lv, Wanjun Chen, Yanfei We. Plumbagin induces autophagy and apoptosis of SMMC-7721 cells in vitro and in vivo. Journal of cellular biochemistry. vol 120. issue 6. 2020-07-15. PMID:30536473. |
real-time polymerase chain reaction and western blot showed that pl treatment suppressed the expression of apoptosis and autophagy factors (lc3, beclin1, atg7, and atg5), which are associated with tumor apoptosis and autophagy in smmc-7721 cells. |
2020-07-15 |
2023-08-13 |
mouse |
| Yuning Lin, Yongxin Chen, Shengshan Wang, Jing Ma, Yue Peng, Xianling Yuan, Beibei Lv, Wanjun Chen, Yanfei We. Plumbagin induces autophagy and apoptosis of SMMC-7721 cells in vitro and in vivo. Journal of cellular biochemistry. vol 120. issue 6. 2020-07-15. PMID:30536473. |
cell apoptosis and autophagy of the transplanted tumors were evaluated by hematoxylin and eosin staining, terminal deoxynucleotidyl transferase-mediated dutp nick end-labeling staining, and western blot. |
2020-07-15 |
2023-08-13 |
mouse |
| Hongna Lai, Rui Wang, Shunying Li, Qianfeng Shi, Zijie Cai, Yudong Li, Yujie Li. LIN9 confers paclitaxel resistance in triple negative breast cancer cells by upregulating CCSAP. Science China. Life sciences. vol 63. issue 3. 2020-07-15. PMID:31420851. |
human tnbc cell lines mda-mb-231 and mda-mb-468 and their corresponding paclitaxel-resistant sublines 231ptx and 468ptx were used to assess the expression of lin9 by qrt-pcr and western blot, cell growth by cell counting, cell viability by mts assay, and cell apoptosis by flow cytometry. |
2020-07-15 |
2023-08-13 |
human |
| Suwen Liu, Yunwen Yang, Huiping Gao, Ning Zhou, Peipei Wang, Yue Zhang, Aihua Zhang, Zhanjun Jia, Songming Huan. Trehalose attenuates renal ischemia-reperfusion injury by enhancing autophagy and inhibiting oxidative stress and inflammation. American journal of physiology. Renal physiology. vol 318. issue 4. 2020-07-14. PMID:32068461. |
western blot analysis, autophagy flux detection, and apoptosis assay were performed to evaluate the level of autophagy and antiapoptotic effect of tre. |
2020-07-14 |
2023-08-13 |
mouse |
| Yong Sun Lee, Ki Cheon Kim, Raj Kumar Mongre, Ji Young Kim, Yu Ri Kim, Dong Young Choi, Sukgil Song, Jaesuk Yun, Sang-Bae Han, Do Young Yoon, Jin Tae Hon. IL-32γ suppresses lung cancer stem cell growth via inhibition of ITGAV-mediated STAT5 pathway. Cell death & disease. vol 10. issue 7. 2020-07-13. PMID:31263095. |
in addition, expression of cell proliferation, apoptosis markers, and signaling molecules was determined by western blot analysis. |
2020-07-13 |
2023-08-13 |
mouse |
| Yongxia Zhu, Weiqiong Zuo, Lijuan Chen, Shasha Bian, Jiayu Jing, Cailin Gan, Xiuli Wu, Hongyao Liu, Xingping Su, Wanglai Hu, Yuqi Guo, Yue Wang, Tinghong Y. Repurposing of the anti-helminthic drug niclosamide to treat melanoma and pulmonary metastasis via the STAT3 signaling pathway. Biochemical pharmacology. vol 169. 2020-07-13. PMID:31465777. |
further, western blot analysis indicated that cell apoptosis was correlated with activation of bax and cleaved caspase-3 and decreased expression of bcl-2. |
2020-07-13 |
2023-08-13 |
Not clear |
| Zhong Li, Yuan Li, Yunhao Jia, Bo Ding, Jinsong Y. Rab1A knockdown represses proliferation and promotes apoptosis in gastric cancer cells by inhibition of mTOR/p70S6K pathway. Archives of biochemistry and biophysics. vol 685. 2020-07-13. PMID:32240637. |
apoptosis was estimated by flow cytometry analysis and western blot analysis of b cell lymphoma 2 (bcl-2), myeloid cell leukemia 1 (mcl-1), bcl-2 associated x (bax), and bcl-2 homologous antagonist/killer (bak) expression. |
2020-07-13 |
2023-08-13 |
rat |
| Wei Wang, Minghui Zhao, Yong Zhao, Wei Shen, Shen Yi. PDGFRα/β-PI3K-Akt pathway response to the interplay of mitochondrial dysfunction and DNA damage in Aroclor 1254-exposed porcine granulosa cells. Environmental pollution (Barking, Essex : 1987). vol 263. issue Pt A. 2020-07-10. PMID:32289613. |
when combined with immunofluorescence, western blot analysis, and real-time rt-pcr analysis, this data showed that the mitochondrial-ros-driven feed-forward loop increased phospho-pdgfrα/β, which stimulates apoptosis by suppressing the pi3k-akt pathway. |
2020-07-10 |
2023-08-13 |
Not clear |
| Feng Jia, Zhen Zhang, Xu Zhan. MicroRNA-338-3p inhibits tumor growth and metastasis in osteosarcoma cells by targeting RUNX2/CDK4 and inhibition of MAPK pathway. Journal of cellular biochemistry. vol 120. issue 4. 2020-07-09. PMID:30484892. |
western blot assay was carried to measure the protein expression levels involved in cell apoptosis, migration, and mitogen-activated protein kinases (mapk) pathway. |
2020-07-09 |
2023-08-13 |
human |
| Yanyong Cheng, Yunfeng Jiang, Yu Sun, Hong Jian. The role of long non-coding RNA SNHG12 in neuroprotection following cerebral ischemic injury. Neuroreport. vol 30. issue 14. 2020-07-09. PMID:31469718. |
and the western blot showed that knockdown small nucleolar rna host gene 12 aggravated the oxygen-glucose deprivation/reoxygen-induced apoptosis. |
2020-07-09 |
2023-08-13 |
Not clear |
| Xiao Liang, Chunhong Xiu, Minghao Liu, Chaolan Lin, Hanchen Chen, Rui Bao, Shusen Yang, Jiangbo Y. Platelet-neutrophil interaction aggravates vascular inflammation and promotes the progression of atherosclerosis by activating the TLR4/NF-κB pathway. Journal of cellular biochemistry. vol 120. issue 4. 2020-07-08. PMID:30302814. |
meanwhile, mouse marrow neutrophils subjected to different treatment were collected for the elisa assay, cell apoptosis, and western blot analysis. |
2020-07-08 |
2023-08-13 |
mouse |