| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jiaxun Tian, Jiamei Mo, Lan Xu, Rui Zhang, Yun Qiao, Bin Liu, Lei Jiang, Siyang Ma, Gang Sh. Scoulerine promotes cell viability reduction and apoptosis by activating ROS-dependent endoplasmic reticulum stress in colorectal cancer cells. Chemico-biological interactions. vol 327. 2020-08-31. PMID:32590070. |
apoptosis was assessed by flow cytometry analysis, caspase-3/7 activity assay, and western blot analysis of bax, bcl-2 and cytochrome c (cyt c) expression. |
2020-08-31 |
2023-08-13 |
Not clear |
| Chyi-Huey Bai, Javad Alizargar, Ching-Yi Peng, Jia-Ping W. Combination of exercise training and resveratrol attenuates obese sarcopenia in skeletal muscle atrophy. The Chinese journal of physiology. vol 63. issue 3. 2020-08-31. PMID:32594063. |
mitochondrial function expression, apoptosis and relative hypertrophy signaling in hfd-induced obesity mice and samp8 mice were determined by western blot analysis. |
2020-08-31 |
2023-08-13 |
mouse |
| Daren Qiu, Mi Zhou, Ting Lin, Junjie Chen, Guanghui Wang, Yujie Huang, Xin Jiang, Wenjing Tian, Haifeng Che. Cytotoxic Components from Hypericum elodeoides Targeting RXRα and Inducing HeLa Cell Apoptosis through Caspase-8 Activation and PARP Cleavage. Journal of natural products. vol 82. issue 5. 2020-08-28. PMID:31038949. |
western blot analysis suggested that 1 and 6 induced apoptosis of hela cells with time- and dose-dependent parp cleavage. |
2020-08-28 |
2023-08-13 |
Not clear |
| Lin Zhang, Benhong Li. Sapylin inhibits lung cancer cell proliferation and promotes apoptosis by attenuating PI3K/AKT signaling. Journal of cellular biochemistry. vol 120. issue 9. 2020-08-27. PMID:31009136. |
western blot was used to determine the expressions of proteins involved in proliferation, apoptosis, and phosphoinositide 3-kinase/serine/threonine kinase (pi3k/akt), wnt3a/β-catenin signaling pathway. |
2020-08-27 |
2023-08-13 |
Not clear |
| Marc Oria, Soner Duru, Rebeca L Figueira, Federico Scorletti, Lucas E Turner, Irati Fernandez-Alonso, Alejandra Fernandez-Martin, Mario Marotta, Lourenco Sbragia, Aimen F Shaaban, Jose L Peir. Cell necrosis, intrinsic apoptosis and senescence contribute to the progression of exencephaly to anencephaly in a mice model of congenital chranioschisis. Cell death & disease. vol 10. issue 10. 2020-08-27. PMID:31558708. |
expression of apoptosis and senescence genes (p53, p21, p16, rbl2, casp3, casp9) was determined by qrt-pcr and protein expression analyzed by western blot. |
2020-08-27 |
2023-08-13 |
mouse |
| Ujjayinee Ray, Sanjay Kumar Raul, Vindya K Gopinatha, Dipayan Ghosh, Kanchugarakoppal S Rangappa, Kempegowda Mantelingu, Sathees C Raghava. Identification and characterization of novel SCR7-based small-molecule inhibitor of DNA end-joining, SCR130 and its relevance in cancer therapeutics. Molecular carcinogenesis. vol 59. issue 6. 2020-08-24. PMID:32189406. |
various cellular assays in conjunction with western blot analysis revealed that treatment with scr130 led to loss of mitochondrial membrane potential leading to cell death by activating both intrinsic and extrinsic pathways of apoptosis. |
2020-08-24 |
2023-08-13 |
mouse |
| Jingze Zhang, Haiming Xu, Licheng Gong, Long Li. MicroRNA-132 protects H9c2 cells against oxygen and glucose deprivation-evoked injury by targeting FOXO3A. Journal of cellular physiology. vol 235. issue 1. 2020-08-21. PMID:31210352. |
after mir-132 mimic and inhibitor transfections, the impacts of mir-132 on ogd-affected h9c2 cell viability, apoptosis, cell cycle, and the interrelated factors were appraised by exploiting cell counting kit-8, flow cytometry, and western blot analysis. |
2020-08-21 |
2023-08-13 |
human |
| Chenlong Song, Yang Han, Huan Luo, Zhiwei Qin, Zhengqian Chen, Yuan Liu, Su Lu, Huimin Sun, Chongzhi Zho. HOXA10 induces BCL2 expression, inhibits apoptosis, and promotes cell proliferation in gastric cancer. Cancer medicine. vol 8. issue 12. 2020-08-21. PMID:31364281. |
by performing western blot, chromatin immunoprecipitation and quantitative pcr (chip-qpcr), and rescue experiment, we found that hoxa10 might bind to bcl2 promoter region, induce its expression, and thus inhibit intrinsic apoptosis pathway. |
2020-08-21 |
2023-08-13 |
Not clear |
| Zhiyuan Hu, Pengjun Zhao, Huifang X. Hyperoside exhibits anticancer activity in non‑small cell lung cancer cells with T790M mutations by upregulating FoxO1 via CCAT1. Oncology reports. vol 43. issue 2. 2020-08-21. PMID:31894285. |
cell viability assays, apoptosis analysis, reverse transcription‑quantitative pcr, western blot analysis, animal experiments and immunohistochemistry were performed to examine the anticancer activity of hyperoside. |
2020-08-21 |
2023-08-13 |
Not clear |
| Farhad Shibani, Ali Sahamsizadeh, Iman Fatemi, Mohammad Allahtavakoli, Jalal Hasanshahi, Mohammadreza Rahmani, Mahdieh Azin, Mahsa Hassanipour, Nazanin Mozafari, Ayat Kaeid. Effect of oleuropein on morphine-induced hippocampus neurotoxicity and memory impairments in rats. Naunyn-Schmiedeberg's archives of pharmacology. vol 392. issue 11. 2020-08-20. PMID:31236657. |
in order to evaluate the cleaved caspase-3, bax, and bcl2 protein expression (as biochemical markers of apoptosis) in ca1 area of hippocampus tissue, the western blot test was used. |
2020-08-20 |
2023-08-13 |
rat |
| Qing Wang, Liqiong Zhang, Meifang Huang, Yuanyuan Zheng, Kai Zhen. Immunomodulatory Effect of Eriocitrin in Experimental Animals with Benzo(a)Pyrene-induced Lung Carcinogenesis. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer. vol 39. issue 2. 2020-08-20. PMID:32749123. |
moreover, the status of apoptosis proteins (bax, caspase-9, and caspase-3) and cell proliferative protein (cyclin d1 and cyclin a) expression was determined by western blot and pcna by immunohistochemical analysis. |
2020-08-20 |
2023-08-13 |
mouse |
| Cuili Ma, Jianwei Chen, Ping L. Geldanamycin induces apoptosis and inhibits inflammation in fibroblast-like synoviocytes isolated from rheumatoid arthritis patients. Journal of cellular biochemistry. vol 120. issue 9. 2020-08-17. PMID:31087698. |
the annexinv/propidium iodide and terminal deoxynucleotidyl transferase dutp nick-end labeling staining confirmed that ga can directly induce apoptosis and subsequently inhibit the growth of ra fls, which was also confirmed by western blot assay. |
2020-08-17 |
2023-08-13 |
mouse |
| Z Wang, Y Li, L Fan, Q Zhao, B Tan, R Liu, F L. Silencing of TPD52 inhibits proliferation, migration, invasion but induces apoptosis of pancreatic cancer cells by deactivating Akt pathway. Neoplasma. vol 67. issue 2. 2020-08-17. PMID:31847526. |
in the present study, after transfecting aspc-1 and panc-1 cells with nc or sh-tpd52, the cck-8 assay, hoechst staining, western blot, transwell assay, flow cytometry were used to examine the cell proliferation, migration, invasion and apoptosis. |
2020-08-17 |
2023-08-13 |
mouse |
| W L Lv, Y Y Hu, Z N Li, W Zhang, Q Pa. PAX3 silencing suppresses gastric cancer proliferation and angiogenesis via MET/PI3K signaling. Neoplasma. vol 67. issue 2. 2020-08-17. PMID:31847528. |
in order to investigate the effect of silencing pax3 on cell apoptosis, angiogenesis and met/pi3k pathway, quantitative real-time pcr (qrt-pcr) or western blot were used to detect the expression levels of caspase-3, vegf, met, p-met, pi3k and p-pi3k. |
2020-08-17 |
2023-08-13 |
mouse |
| Jiao Liu, Yazhuo Guo, Jing Ca. Matrine triggers colon cancer cell apoptosis and G0/G1 cell cycle arrest via mediation of microRNA-22. Phytotherapy research : PTR. vol 34. issue 7. 2020-08-07. PMID:32072698. |
cell viability, apoptosis, cell cycle, and the correlative proteins were assessed via cell counting kit-8, flow cytometry, and western blot. |
2020-08-07 |
2023-08-13 |
Not clear |
| Chao Han, Yuanyuan Wei, Yumeng Geng, Yuqing Cui, Shuying Li, Yongzhan Bao, Wanyu Sh. Bisphenol A in utero exposure induces ovary dysfunction in mice offspring and the ameliorating effects of Cuscuta chinensis flavonoids. Environmental science and pollution research international. vol 27. issue 25. 2020-08-07. PMID:32488702. |
the expression of caspase-7, caspase-9, bcl-2, and bax in ovaries and testes of offspring mice were detected by western blot, and apoptosis in ovaries and testes was detected by tunel. |
2020-08-07 |
2023-08-13 |
mouse |
| Xin Liu, HuaWen Xu, YueQi Zhang, Peng Wang, Wei Ga. Brusatol inhibits amyloid-β-induced neurotoxicity in U-251 cells via regulating the Nrf2/HO-1 pathway. Journal of cellular biochemistry. vol 120. issue 6. 2020-08-05. PMID:30629288. |
after running hoechst and western blot assays, br prevented cell apoptosis induced by aβ in u-251 cells. |
2020-08-05 |
2023-08-13 |
Not clear |
| Fenghua Lv, Zhuo Wang, Yanli Huang, Aoyang Si, Yulei Che. CLEC3B protects H9c2 cardiomyocytes from apoptosis caused by hypoxia via the PI3K/Akt pathway. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 9. 2020-07-31. PMID:32696821. |
then, cell counting kit-8 (cck-8), flow cytometry, qrt-pcr, and western blot assays were performed to investigate cell viability, apoptosis, and expression levels of clec3b, phosphatidylinositol 3-kinase (pi3k), phosphorylated pi3k (p-pi3k), protein kinase b (akt), phosphorylated akt (p-akt), and cleaved-caspase 3. |
2020-07-31 |
2023-08-13 |
rat |
| Ye Liu, Wei Zheng, Yue Pan, Jing H. Low expression of miR-186-5p regulates cell apoptosis by targeting toll-like receptor 3 in high glucose-induced cardiomyocytes. Journal of cellular biochemistry. vol 120. issue 6. 2020-07-27. PMID:30506923. |
apoptosis was detected in hg-treated cardiomyocytes by flow cytometry and western blot analysis. |
2020-07-27 |
2023-08-13 |
Not clear |
| Xiaobao Fan, Zhenjiang Li, Xiaoming Wang, Jing Wang, Zhiming Ha. Silencing of KPNA2 inhibits high glucose-induced podocyte injury via inactivation of mTORC1/p70S6K signaling pathway. Biochemical and biophysical research communications. vol 521. issue 4. 2020-07-27. PMID:31727365. |
the cell viability was tested by cck-8 kit, the apoptosis was measured using flow cytometry assay, the apoptotic and the autophagy related genes was detected by western blot. |
2020-07-27 |
2023-08-13 |
Not clear |