| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bianka Gurbi, Diána Brauswetter, Attila Varga, Pál Gyulavári, Kinga Pénzes, József Murányi, Veronika Zámbó, Ede Birtalan, Tibor Krenács, David Laurence Becker, Miklós Csala, István Vályi-Nagy, István Peták, Kornél Dáno. The Potential Impact of Connexin 43 Expression on Bcl-2 Protein Level and Taxane Sensitivity in Head and Neck Cancers-In Vitro Studies. Cancers. vol 11. issue 12. 2020-09-28. PMID:31766723. |
human papillomavirus (hpv) negative hnscc cell lines were tested for paclitaxel sensitivity through measuring apoptosis induction, cell viability and changes in cx43 and bcl-2 levels using flow cytometry, cell viability assay, immunocytochemistry and western blot. |
2020-09-28 |
2023-08-13 |
human |
| Dake Hao, Chuanchao He, Bowen Ma, Lee Lankford, Lizette Reynaga, Diana L Farmer, Fuzheng Guo, Aijun Wan. Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering. Stem cells international. vol 2019. 2020-09-28. PMID:31781252. |
caspase-3, mts, and western blot analysis showed hp significantly reduced the apoptosis of cv-mscs under ischemic stimulus via the activation of the akt signaling pathway that was related to cell survival. |
2020-09-28 |
2023-08-13 |
human |
| Mohsen Keshavarz, Amir Sasan Mozaffari Nejad, Maryam Esghaei, Farah Bokharaei-Salim, Hassan Dianat-Moghadam, Hossein Keyvani, Amir Ghaem. Oncolytic Newcastle disease virus reduces growth of cervical cancer cell by inducing apoptosis. Saudi journal of biological sciences. vol 27. issue 1. 2020-09-28. PMID:31889816. |
in addition, molecular changes of early stage of apoptosis and the role of reactive oxygen species (ros) were analyzed by flow cytometry and western blot in ndv-treated tc-1 cells. |
2020-09-28 |
2023-08-13 |
human |
| Ying Wen, Xiaoyan Cai, Shaolian Chen, Wei Fu, Dong Chai, Huainian Zhang, Yongli Zhan. 7-Methoxy-1-Tetralone Induces Apoptosis, Suppresses Cell Proliferation and Migration in Hepatocellular Carcinoma via Regulating c-Met, p-AKT, NF-κB, MMP2, and MMP9 Expression. Frontiers in oncology. vol 10. 2020-09-28. PMID:32117722. |
mtt assay assessed hcc cell viability; cell apoptosis of hcc cells was determined by flow cytometry; wound healing assay evaluated hcc cell migratory ability; protein expression levels were assessed using western blot assay; the |
2020-09-28 |
2023-08-13 |
Not clear |
| Tingting Zhang, Chang Liu, Shanshan Ma, Yirong Gao, Rensheng Wan. Protective Effect and Mechanism of Action of Rosmarinic Acid on Radiation-Induced Parotid Gland Injury in Rats. Dose-response : a publication of International Hormesis Society. vol 18. issue 1. 2020-09-28. PMID:32127788. |
saliva secretion function, oxidative stress, apoptosis, the inflammatory response, and fibrosis were determined by the measurement of the salivary flow rate, enzyme-linked immunosorbent assay, transferase-mediated dutp nick end labeling, western blot, quantitative real time polymerase chain reaction, and hematoxylin and eosin staining. |
2020-09-28 |
2023-08-13 |
rat |
| Wenjun Li, Qian Du, Xiaoli Li, Xiangru Zheng, Feng Lv, Xin Xi, Guili Huang, Jia Yang, Songqing Li. Eriodictyol Inhibits Proliferation, Metastasis and Induces Apoptosis of Glioma Cells Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32158391. |
in addition, eriodictyol induces apoptosis in u87mg and chg-5 cells, as evaluated by flow cytometry, immunofluorescence, and western blot. |
2020-09-28 |
2023-08-13 |
mouse |
| Yingfang Xing, Zhewei Cai, Meijuan Xu, Wenzheng Ju, Xiaojun Luo, Yaojuan Hu, Xiaoyan Liu, Tuli Kang, Ping Wu, Chenxin Cai, Jun-Jie Zh. Raman observation of a molecular signaling pathway of apoptotic cells induced by photothermal therapy. Chemical science. vol 10. issue 47. 2020-09-28. PMID:32190245. |
through sers spectra and their synchronous and asynchronous sers correlation maps, the occurrence and dynamics of a cascade of molecular events have been investigated, and a molecular signaling pathway of pptt-induced apoptosis, including release of cytochrome c, protein degradation, and dna fragmentation, was revealed, which was also demonstrated by metabolomics, agarose gel electrophoresis, and western blot analysis, respectively. |
2020-09-28 |
2023-08-13 |
Not clear |
| Yingfang Xing, Zhewei Cai, Meijuan Xu, Wenzheng Ju, Xiaojun Luo, Yaojuan Hu, Xiaoyan Liu, Tuli Kang, Ping Wu, Chenxin Cai, Jun-Jie Zh. Raman observation of a molecular signaling pathway of apoptotic cells induced by photothermal therapy. Chemical science. vol 10. issue 47. 2020-09-28. PMID:32190245. |
combined with western blot results, this intrinsic mitochondria-mediated apoptosis pathway was further demonstrated to be initiated by a bh3-only protein, bid. |
2020-09-28 |
2023-08-13 |
Not clear |
| Dengtao Liu, Ping Han, Chunhai Gao, Wei Gao, Xiaocui Yao, Shulan Li. microRNA-155 Modulates Hepatic Stellate Cell Proliferation, Apoptosis, and Cell Cycle Progression in Rats With Alcoholic Hepatitis Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32317960. |
the biological prediction website microrna.org and dual-luciferase reporter gene assay were used to identify whether socs1 was a direct target of mir-155, and the effects of mir-155 and socs1 on the viability, cycle progression, and apoptosis of hepatic stellate cells were assessed using rt-qpcr, western blot assay, mtt assay, annexin v/pi double staining, and pi single staining. |
2020-09-28 |
2023-08-13 |
rat |
| Hongyun Cheng, Xue Jiang, Qian Zhang, Jun Ma, Ronghui Cheng, Hongmei Yong, Huichang Shi, Xueyi Zhou, Liyue Ge, Guangyi Ga. Naringin inhibits colorectal cancer cell growth by repressing the PI3K/AKT/mTOR signaling pathway. Experimental and therapeutic medicine. vol 19. issue 6. 2020-09-28. PMID:32346444. |
the degree of apoptosis and the expression of apoptosis-related proteins (bcl-2 and bax) in crc cells stimulated by naringin was detected using flow cytometry and western blot assays, respectively. |
2020-09-28 |
2023-08-13 |
Not clear |
| Shi-Yi Lin, Tian-Qi Wang, Lu-Ting Xu, Xiao-Xiao Lai, Yan Shen, Jian-Wei Lin, Shi-Yu Gao, Hai-Yan H. Qingxin Kaiqiao Recipe Improves Cognitive Performance, Inhibits Apoptosis, and Reduces Pathological Deposits in APP/PS1 Double Transgenic Mice via the PI3K/Akt Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2020. 2020-09-28. PMID:32419798. |
morris water maze (mwm) was used to test the ability of spatial navigation and memorization; terminal deoxynucleotidyl transferase-mediated dutp nick end-labelling (tunel) assay was applied to test the apoptosis; amyloid protein granule deposition was detected via methenamine silver staining; western blot (wb) analysis, immunohistochemistry, and rt-pcr were applied to measure the expression of a |
2020-09-28 |
2023-08-13 |
mouse |
| Wenjun Wang, Shengzheng Wang, Tianlong Liu, Yang Ma, Shaojie Huang, Lu Lei, Aidong Wen, Yi Din. Resveratrol: Multi-Targets Mechanism on Neurodegenerative Diseases Based on Network Pharmacology. Frontiers in pharmacology. vol 11. 2020-09-28. PMID:32477148. |
western blot results confirmed that resveratrol inhibited glutamate-induced apoptosis of hippocampal neurons partly by regulating the pi3k/akt/mtor pathway. |
2020-09-28 |
2023-08-13 |
Not clear |
| Junling Liu, Jianyun Liu, Mingming Bai, Hui Wan. Protective effect of puerarin against burn-induced heart injury in rats. Experimental and therapeutic medicine. vol 20. issue 1. 2020-09-28. PMID:32536996. |
tunel staining and western blot analysis of cleaved and pro-caspase-3 were also performed to assess apoptosis. |
2020-09-28 |
2023-08-13 |
rat |
| Mingzhu Zong, Wanting Feng, Li Wan, Xiaojuan Yu, Weiyong Y. miR-203 affects esophageal cancer cell proliferation, apoptosis and invasion by targeting MAP3K1. Oncology letters. vol 20. issue 1. 2020-09-28. PMID:32566001. |
cell apoptosis was analyzed via flow cytometry, caspase 8/3 assay kits and western blot analysis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Yang Cui, Rui Chen, Lin Ma, Wenjing Yang, Mingyue Chen, Yanghai Zhang, Shuai Yu, Wuzi Dong, Wenxian Zeng, Xianyong Lan, Chuanying Pa. miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway. Frontiers in cell and developmental biology. vol 8. 2020-09-28. PMID:32596241. |
through qrt-pcr, western blot (wb), tunel, edu and flow cytometry, mir-205 was found to induce cell apoptosis, but did not affect proliferation or differentiation in both tm3 and gc-1spg mouse cell lines. |
2020-09-28 |
2023-08-13 |
mouse |
| Zahra Kargarpour, Jila Nasirzade, Francesca Di Summa, Layla Panahipour, Richard J Miron, Reinhard Grube. Platelet-Rich Fibrin Can Neutralize Hydrogen Peroxide-Induced Cell Death in Gingival Fibroblasts. Antioxidants (Basel, Switzerland). vol 9. issue 6. 2020-09-28. PMID:32604944. |
cell apoptosis was assessed by cleaved caspase-3 western blot analysis. |
2020-09-28 |
2023-08-13 |
Not clear |
| Qilin Feng, Qingchun Yao, Bo Li, Yongsheng Xie, Hui Zhang, Zhijian Xu, Kang Lu, Ke Hu, Yao Cheng, Bingqing Shi, Cheng Huang, Liping Li, Xiaosong Wu, Shanxi You, Jumei Shi, Weiliang Zh. Glycolysis is suppressed by DCZ0801-induced inactivation of the Akt/mTOR pathway in Multiple Myeloma. Journal of Cancer. vol 11. issue 16. 2020-09-28. PMID:32626538. |
the cell counting kit-8 assay, apoptosis detection, cell cycle analysis, western blot analysis, and tumor xenograft models were used to determine the effect of dcz0801 treatment both |
2020-09-28 |
2023-08-13 |
Not clear |
| Ying-Jung Hsu, Chao-Wen Lin, Sheng-Li Cho, Wei-Shiung Yang, Chung-May Yang, Chang-Hao Yan. Protective Effect of Fenofibrate on Oxidative Stress-Induced Apoptosis in Retinal-Choroidal Vascular Endothelial Cells: Implication for Diabetic Retinopathy Treatment. Antioxidants (Basel, Switzerland). vol 9. issue 8. 2020-09-28. PMID:32764528. |
western blot analysis revealed that fenofibrate repressed apoptosis through cytosolic and mitochondrial apoptosis signal-regulated kinase-1 (ask)-trx-related signaling pathways, including c-jun amino-terminal kinase (jnk) phosphorylation, cytochrome c release, caspase 3 activation, and poly (adp-ribose) polymerase-1 (parp-1) cleavage. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xiaozhi Deng, Lihong Shang, Min Du, Lan Yuan, Lijing Xiong, Xiaoli Xi. Mechanism underlying the significant role of the miR-4262/SIRT1 axis in children with inflammatory bowel disease. Experimental and therapeutic medicine. vol 20. issue 3. 2020-09-28. PMID:32765699. |
mtt assay, flow cytometry and western blot analysis were performed to assess cell viability, apoptosis and nf-κb signaling pathway-related protein levels, respectively. |
2020-09-28 |
2023-08-13 |
Not clear |
| Shefeng Zheng, Jinnv Liu, Zhangjian Zhao, Ruifang Son. Role of STAT3/mTOR pathway in chronic kidney injury. American journal of translational research. vol 12. issue 7. 2020-09-28. PMID:32774701. |
glomerular mesangial cells were divided into control group, model group, stat3 inhibitor (s3i-201) group followed by analysis of cell proliferation by mtt assay, cell apoptosis by flow cytometry, formation of autophagosomes by electron microscopy, expression of stat3/mtor signaling proteins and autophagy proteins lc3ii and p62 by western blot, expression of e-cadherin and vimentin by immunofluorescence. |
2020-09-28 |
2023-08-13 |
mouse |