| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming-Xin Ren, Xiao-Hui Deng, Fang Ai, Guo-Yan Yuan, Hai-Yan Son. Effect of quercetin on the proliferation of the human ovarian cancer cell line SKOV-3 Experimental and therapeutic medicine. vol 10. issue 2. 2020-09-29. PMID:26622357. |
cell apoptosis was determined using hoechst staining, and western blot analysis was used to analyze changes in the expression levels of survivin protein. |
2020-09-29 |
2023-08-13 |
human |
| Yanting Kang, Wanle Hu, Encheng Bai, Hailun Zheng, Zhiguo Liu, Jianzhang Wu, Rong Jin, Chengguang Zhao, Guang Lian. Curcumin sensitizes human gastric cancer cells to 5-fluorouracil through inhibition of the NFκB survival-signaling pathway. OncoTargets and therapy. vol 9. 2020-09-29. PMID:27980427. |
flow cytometry and western blot analysis results showed that the combination of curcumin and 5-fu caused synergistic inhibition of growth and induction of potent apoptosis in the resistant cancer cell lines in vitro. |
2020-09-29 |
2023-08-13 |
human |
| Fu-Xia Song, Li Wang, Hong Liu, Ying-Li Wang, Yong Zo. Brain cell apoptosis inhibition by butylphthalide in Alzheimer's disease model in rats. Experimental and therapeutic medicine. vol 13. issue 6. 2020-09-29. PMID:28587340. |
all rats were sacrificed after 30 days; the brain tissues were used for testing for apoptosis by the terminal deoxynucleotidyl-transferase-mediated dutp nick end labelling (tunel) staining method, for determining mitogen-activated protein kinase (mapk), erk and p21 protein by western blot analysis, and their cognate mrna levels by rt-pcr. |
2020-09-29 |
2023-08-13 |
rat |
| Yitao Wan, Yuan Yuan, Yueyin Pan, Ying Zhan. Antitumor activity of high-dose pulsatile gefitinib in non-small-cell lung cancer with acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors. Experimental and therapeutic medicine. vol 13. issue 6. 2020-09-29. PMID:28587381. |
cell apoptosis and cycling were also determined by flow cytometry and the expression of phospho (p)-egfr, egfr, p-akt and akt were measured by western blot analysis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Isaac Kim, Kwang-Soo Kim, Ok-Seon Kwon, Hyuk-Jin Cha, Kyung-Soon Par. Ell3 stimulates 5-FU resistance in a breast cancer cell line. Oncology letters. vol 13. issue 6. 2020-09-29. PMID:28588704. |
furthermore, the expression levels of survivin, which is a direct transcriptional target of wnt/β-catenin and an inhibitor of apoptosis, were markedly elevated when ell3 oe cells were treated with 5-fu, as detected by western blot analysis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Ziyin Lu, Chunli Chen, Zhiyong Wu, Yusong Miao, Ishfaq Muhammad, Liangjun Ding, Erjie Tian, Wanjun Hu, Huilin Ni, Rui Li, Bo Wang, Jichang L. A Dual Role of P53 in Regulating Colistin-Induced Autophagy in PC-12 Cells. Frontiers in pharmacology. vol 8. 2020-09-29. PMID:29163157. |
the hallmarks of autophagy and apoptosis were examined by real-time pcr and western blot, fluorescence/immunofluorescence microscopy, and electron microscopy. |
2020-09-29 |
2023-08-13 |
Not clear |
| Shu-Jun Zhang, Jie Yao, Bao-Zhong Shen, Guang-Bo Li, Shan-Shan Kong, Dan-Dan Bi, Shang-Ha Pan, Bing-Lin Chen. Role of piwi-interacting RNA-651 in the carcinogenesis of non-small cell lung cancer. Oncology letters. vol 15. issue 1. 2020-09-29. PMID:29399156. |
the association between pir651 expression and apoptosis was evaluated by flow cytometry and western blot analysis. |
2020-09-29 |
2023-08-13 |
human |
| Mo Zhou, Jinkai Zheng, Jinfeng Bi, Xinye Wu, Jian Lyu, Kun Ga. Synergistic inhibition of colon cancer cell growth by a combination of atorvastatin and phloretin. Oncology letters. vol 15. issue 2. 2020-09-29. PMID:29399200. |
the data obtained by flow cytometry and western blot analysis of cleaved-poly (adp-ribose) polymerase indicated a synergistic effect resulted in apoptosis and cell cycle arrest at the g |
2020-09-29 |
2023-08-13 |
Not clear |
| Ning Yang, Shuzhan Yao, Dong Li. Tumor necrosis factor-related apoptosis-inducing ligand additive with Iodine-131 of inhibits non-small cell lung cancer cells through promoting apoptosis. Oncology letters. vol 16. issue 1. 2020-09-29. PMID:29928412. |
results demonstrated that trail-i-131 treatment induced apoptosis of nsclc cells, with western blot analysis confirming that trail-i-131 treatment increased proapoptotic bad and bax expression levels, while antiapoptotic bcl-2 and bcl-w protein levels were decreased in nsclc cells. |
2020-09-29 |
2023-08-13 |
human |
| Qin Zhang, He Xiao, Feng Jin, Mengxia Li, Jia Luo, Ge Wan. Cetuximab improves AZD6244 antitumor activity in colorectal cancer HT29 cells Oncology letters. vol 16. issue 1. 2020-09-29. PMID:29928418. |
ht29 cells were treated with azd6244 plus cetuximab and then subjected to the following assays: cell counting kit-8, brdu-incorporation, flow cytometric cell cycle distribution and apoptosis analysis, western blot analysis, and nude mouse xenografts. |
2020-09-29 |
2023-08-13 |
mouse |
| Yang Wang, Chunhui Zheng, Teng Li, Rui Zhang, Yang Wang, Jiaxin Zhang, Qingsi He, Zuocheng Sun, Xinsheng Wan. Long noncoding RNA Z38 promotes cell proliferation and metastasis and inhibits cell apoptosis in human gastric cancer. Oncology letters. vol 16. issue 5. 2020-09-29. PMID:30333877. |
finally, western blot analysis further demonstrated the role of z38 in the apoptosis of ags and mkn74 cells. |
2020-09-29 |
2023-08-13 |
human |
| Jiacui Zhang, Keping Jiao, Jing Liu, Yu Xi. Metformin reverses the resistance mechanism of lung adenocarcinoma cells that knocks down the Nrf2 gene. Oncology letters. vol 16. issue 5. 2020-09-29. PMID:30333878. |
in the present study, reverse-transcription quantitative polymerase chain reaction, cell transfection, western blot analysis, a cell counting kit-8 assay and apoptosis detection were used to investigate the above in the a549 cell line and cisplatin-resistant a549 cells (a549/ddp). |
2020-09-29 |
2023-08-13 |
Not clear |
| Yao Xie, Fei Zhou, Xia Zha. TNFAIP8 promotes cell growth by regulating the Hippo pathway in epithelial ovarian cancer. Experimental and therapeutic medicine. vol 16. issue 6. 2020-09-29. PMID:30546405. |
the results of the western blot analysis suggested that tnfaip8 inhibited the expression of phosphorylated yes-associated protein 1 (yap) while promoting total and nuclear yap expression, followed by the regulation of apoptosis and cell cycle checkpoint protein expression in eoc. |
2020-09-29 |
2023-08-13 |
Not clear |
| Rocío Jiménez-Guerrero, Jessica Gasca, M Luz Flores, Begoña Pérez-Valderrama, Cristina Tejera-Parrado, Rafael Medina, María Tortolero, Francisco Romero, Miguel A Japón, Carmen Sáe. Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells. Cancers. vol 10. issue 12. 2020-09-29. PMID:30563080. |
apoptosis, cell cycle, and autophagy were measured by western blot, flow cytometry, and fluorescence microscopy. |
2020-09-29 |
2023-08-13 |
Not clear |
| Meng Wang, Guoyue Lv, Chao Jiang, Shuli Xie, Guangyi Wan. miR-302a inhibits human HepG2 and SMMC-7721 cells proliferation and promotes apoptosis by targeting MAP3K2 and PBX3. Scientific reports. vol 9. issue 1. 2020-09-29. PMID:30765768. |
in addition, an increased mir-302a level in hepg2 cells and smmc-7721 cells were achieved through transfection with mir-302a mimics, and the effects on hepg2 cell and smmc-7721 cell proliferation, apoptosis and mapk pathways were determined using mtt, flow cytometry, qpcr and western blot assays. |
2020-09-29 |
2023-08-13 |
human |
| Qing Sun, Liang-Liang Hu, Qiang F. MCT4 promotes cell proliferation and invasion of castration-resistant prostate cancer PC-3 cell line. EXCLI journal. vol 18. 2020-09-29. PMID:31217781. |
cck-8, transwell migration assay, flow cytometry, and tunel methods were used to detect the proliferation, invasion and apoptosis of pc-3 cells by mct4 knockdown, and the expression of invasion-related proteins (mct4) was detected by western blot analysis. |
2020-09-29 |
2023-08-13 |
Not clear |
| Zhizhong Zhang, Yuanbo Zhang, Rongbin Zho. Loss of Annexin A5 expression attenuates the lipopolysaccharide-induced inflammatory response of rat alveolar macrophages. Cell biology international. vol 44. issue 2. 2020-09-29. PMID:31502716. |
cell apoptosis and expressions of messenger rnas (mrnas) and protein were determined by flow cytometry, quantitative real-time polymerase chain reaction (qrt-pcr), and western blot, respectively. |
2020-09-29 |
2023-08-13 |
rat |
| Hanting Xia, Duanguang Cao, Fo Yang, Wenlong Yang, Wei Li, Pu Liu, Shuhao Wang, Fengyun Yan. Jiawei Yanghe decoction ameliorates cartilage degradation in vitro and vivo via Wnt/β-catenin signaling pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 122. 2020-09-29. PMID:31918279. |
the qrt-pcr and western blot results showed that mrna and protein expressions of wnt signaling pathway related genes β-catenin and cyclind1, apoptosis related genes casapase-3 and caspase-9, collagen degradation related genes metalloproteinase (mmp)-3 and mmp-13 were up-regulated, and col2a1 was down-regulated on il-1β-induced chondrocytes. |
2020-09-29 |
2023-08-13 |
rat |
| Puneet Khandelwal, Aftab Alam, Arpankumar Choksi, Samit Chattopadhyay, Pankaj Podda. Retention of Anticancer Activity of Curcumin after Conjugation with Fluorescent Gold Quantum Clusters: An in Vitro and in Vivo Xenograft Study. ACS omega. vol 3. issue 5. 2020-09-28. PMID:30023902. |
the western blot assay indicated that c-au qcs promote apoptosis in cancer cells. |
2020-09-28 |
2023-08-13 |
mouse |
| He-Yan Zhao, Sheng-Tong Zhang, Xiang Cheng, Hao-Ming Li, Lei Zhang, Hui He, Jian-Bing Qin, Wei-Ye Zhang, Yan Sun, Guo-Hua Ji. Long non-coding RNA GAS5 promotes PC12 cells differentiation into Tuj1-positive neuron-like cells and induces cell cycle arrest. Neural regeneration research. vol 14. issue 12. 2020-09-28. PMID:31397350. |
apoptosis was detected by flow cytometry, while expression of acetylcholine in cells was detected by western blot assay. |
2020-09-28 |
2023-08-13 |
rat |