| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Guang-Xing Meng, Qiang Yuan, Li-Ping Wei, Hua Meng, Yi-Jun Wan. Protein kinase C-β inhibitor treatment attenuates hepatic ischemia and reperfusion injury in diabetic rats. Experimental and therapeutic medicine. vol 11. issue 2. 2020-09-30. PMID:26893648. |
apoptosis of hepatic cells was examined by the western blot analysis of caspase 3 expression and by dna ladder analysis. |
2020-09-30 |
2023-08-13 |
rat |
| June Lee, Jong-Su Kang, Bu-Young Choi, Young-Sam Keu. Sensitization of 5-Fluorouracil-Resistant SNUC5 Colon Cancer Cells to Apoptosis by α-Mangostin. Biomolecules & therapeutics. vol 24. issue 6. 2020-09-30. PMID:27469143. |
western blot analysis illustrated that α-mangostin-induced apoptosis was mediated by the activation of the extrinsic and intrinsic pathways in snuc5/5-fur cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Hui Wang, Yihua Bei, Peipei Huang, Qiulian Zhou, Jing Shi, Qi Sun, Jiuchang Zhong, Xinli Li, Xiangqing Kong, Junjie Xia. Inhibition of miR-155 Protects Against LPS-induced Cardiac Dysfunction and Apoptosis in Mice. Molecular therapy. Nucleic acids. vol 5. issue 10. 2020-09-30. PMID:27727247. |
pharmacological inhibition of mir-155 using antagomir improved cardiac function and suppressed cardiac apoptosis induced by lps in mice as determined by echocardiography, terminal deoxynucleotidyl transferase nick-end labeling (tunel) assay, and western blot for bax and bcl-2, while overexpression of mir-155 using agomir had inverse effects. |
2020-09-30 |
2023-08-13 |
mouse |
| Hui Wang, Yihua Bei, Peipei Huang, Qiulian Zhou, Jing Shi, Qi Sun, Jiuchang Zhong, Xinli Li, Xiangqing Kong, Junjie Xia. Inhibition of miR-155 Protects Against LPS-induced Cardiac Dysfunction and Apoptosis in Mice. Molecular therapy. Nucleic acids. vol 5. issue 10. 2020-09-30. PMID:27727247. |
pea15a was identified as a target gene of mir-155, mediating its effects in controlling apoptosis of cardiomyocytes as evidenced by luciferase reporter assays, quantitative real time-polymerase chain reaction, western blot, and tunel staining. |
2020-09-30 |
2023-08-13 |
mouse |
| Wenxian Zheng, Shuyan Han, Shantong Jiang, Lina Pang, Xiaohong Li, Xijuan Liu, Minhua Cao, Pingping L. Multiple effects of Xihuang pill aqueous extract on the Hs578T triple-negative breast cancer cell line. Biomedical reports. vol 5. issue 5. 2020-09-30. PMID:27882217. |
first, an mtt assay was used to evaluate the anti-proliferative activity of aexhp on the hs578t cell line; furthermore, the cell cycle distribution, mitochondrial membrane potential and apoptotic rate were determined by flow cytometry, and western blot analysis was used to assess the expression of apoptosis and cell cycle regulatory proteins to investigate the mechanisms of action. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yi Xiao, Changliang Su, Taoran Den. miR-223 decreases cell proliferation and enhances cell apoptosis in acute myeloid leukemia via targeting FBXW7. Oncology letters. vol 12. issue 5. 2020-09-30. PMID:27900032. |
following transfection with mir-223, cell viability assays, cell apoptosis assays, western blot analysis and luciferase assays were conducted in aml cell lines. |
2020-09-30 |
2023-08-13 |
human |
| Longyun Chen, Huimin Che. Effect of Mahuang Gancao Ganjiang Decoction on Fusion and Fission of Mitochondria and Apoptosis of Lymphocytes in Mice under Cold Stress. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:28191022. |
western blot analysis showed that these cells expressed decreased fusion-related proteins mitofusin 1 (mfn1), mitofusin 2 (mfn2), and optic atrophy protein-1 (opa-1) and increased fission-related proteins dynamin-related protein 1 (drp1) and fission 1 (fis-1); our results also show that decreased mitochondrial fusion induces cell apoptosis during cold stress. |
2020-09-30 |
2023-08-13 |
mouse |
| Jue Wang, Bin Cao, Dong Han, Miao Sun, Juan Fen. Long Non-coding RNA H19 Induces Cerebral Ischemia Reperfusion Injury via Activation of Autophagy. Aging and disease. vol 8. issue 1. 2020-09-30. PMID:28203482. |
real-time pcr, flow cytometry, immunofluorescence and western blot were used to evaluate the level of lncrna h19, apoptosis, autophagy and some related proteins. |
2020-09-30 |
2023-08-13 |
rat |
| Jianjun Chen, Zhenjun Wang, Sanshui Y. AIM2 regulates viability and apoptosis in human colorectal cancer cells via the PI3K/Akt pathway. OncoTargets and therapy. vol 10. 2020-09-30. PMID:28243117. |
western blot analysis showed that aim2 promoted apoptosis in crc cells by suppressing the phosphatidylinositol 3-kinase (pi3k)/protein kinase b (akt) pathway. |
2020-09-30 |
2023-08-13 |
human |
| Wenjing Zhang, Yi Li, Rui Li, Yaya Wang, Mengwen Zhu, Bowen Wang, Yanling Li, Dongyun Li, Ping Xie, Bin Li. Sodium Tanshinone IIA Sulfonate Prevents Radiation-Induced Toxicity in H9c2 Cardiomyocytes. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:28386289. |
apoptosis was measured by the flow cytometry, hoechst 33258, clonogenic survival assay, and western blot. |
2020-09-30 |
2023-08-13 |
Not clear |
| Yongyue Gao, Zong Zhuang, Shanting Gao, Xiang Li, Zihuan Zhang, Zhennan Ye, Liwen Li, Chao Tang, Mengliang Zhou, Xiao Han, Jie L. Tetrahydrocurcumin reduces oxidative stress-induced apoptosis via the mitochondrial apoptotic pathway by modulating autophagy in rats after traumatic brain injury. American journal of translational research. vol 9. issue 3. 2020-09-30. PMID:28386319. |
we used western blot analysis to evaluate the effect of thc on proteins involved in mitochondrial autophagy and apoptosis after tbi. |
2020-09-30 |
2023-08-13 |
rat |
| Yan-Yan Li, Yin Xiang, Song Zhang, Yan Wang, Jie Yang, Wei Liu, Feng-Tai Xu. Thioredoxin-2 protects against oxygen-glucose deprivation/reperfusion injury by inhibiting autophagy and apoptosis in H9c2 cardiomyocytes. American journal of translational research. vol 9. issue 3. 2020-09-30. PMID:28386372. |
the effects of trx2 on autophagy and apoptosis were measured by transmission electron microscopy (tem), western blot, and flow cytometry. |
2020-09-30 |
2023-08-13 |
Not clear |
| Rosita A Condorelli, Sandro La Vignera, Filippo Giacone, Linda Iacoviello, Laura M Mongioì, Giovanni Li Volti, Ignazio Barbagallo, Roberto Avola, Aldo E Caloger. Nicotine Effects and Receptor Expression on Human Spermatozoa: Possible Neuroendocrine Mechanism. Frontiers in physiology. vol 8. 2020-09-30. PMID:28400736. |
spermatozoa were incubated with nic 100 ng/ml and the nachr antagonist, hexamethonium (hex) (0, 100, 1,000, 10,000 ng/ml) for 3 and 24 h. the following sperm parameters evaluated: (a) progressive motility; (b) mitochondrial membrane potential (mmp); (c) chromatin compactness; (d) externalization of phosphatidylserine (ps); (e) late apoptosis; (f) viability; (g) dna fragmentation; (h) degree of lipid peroxidation (lp) by flow cytometry; (i) nachr subunits expression by quantitative real time pcr and (j) protein expression evaluation by western blot analysis. |
2020-09-30 |
2023-08-13 |
human |
| In-Suk Bae, Choong-Hyun Kim, Jae-Min Kim, Jin-Hwan Cheong, Je-Il Ryu, Myung-Hoon Ha. Correlation of survivin and B-cell lymphoma 2 expression with pathological malignancy and anti-apoptotic properties of glial cell tumors. Biomedical reports. vol 6. issue 4. 2020-09-30. PMID:28413637. |
survivin and bcl-2 expression levels were investigated by western blot analysis, and apoptosis was detected by dna fragmentation analysis. |
2020-09-30 |
2023-08-13 |
human |
| Bo Huang, Fei Xiong, Siwang Wang, Xianping Lang, Xiaodong Wang, Hongli Zho. Effect of SATB1 silencing on the proliferation, invasion and apoptosis of TE-1 esophageal cancer cells. Oncology letters. vol 13. issue 5. 2020-09-30. PMID:28521398. |
western blot analysis, a cell counting kit, transwell chamber assays and flow cytometry were used to assess the effect of satb1-sirna on the proliferation, invasion and apoptosis of cells. |
2020-09-30 |
2023-08-13 |
human |
| Bing Wang, Hong Jiang, Limin Wang, Xueqin Chen, Kan Wu, Shirong Zhang, Shenglin Ma, Bing Xi. Increased MIR31HG lncRNA expression increases gefitinib resistance in non-small cell lung cancer cell lines through the EGFR/PI3K/AKT signaling pathway. Oncology letters. vol 13. issue 5. 2020-09-30. PMID:28529576. |
the egfr/pi3k/akt signaling pathway and mitochondrial apoptosis protein expression levels were assessed by western blot analysis. |
2020-09-30 |
2023-08-13 |
Not clear |
| Fangfang Li, Luyang Miao, Hua Sun, Yuyang Zhang, Xiuqi Bao, Dan Zhan. Establishment of a new acute-on-chronic liver failure model. Acta pharmaceutica Sinica. B. vol 7. issue 3. 2020-09-30. PMID:28540169. |
liver injury was assessed by histopathological analysis and biochemical indices, and apoptosis was detected by western blot and tunel analysis. |
2020-09-30 |
2023-08-13 |
rat |
| Shuoqiang Hu, Shujun Cao, Jinghua Li. Role of angiopoietin-2 in the cardioprotective effect of fibroblast growth factor 21 on ischemia/reperfusion-induced injury in H9c2 cardiomyocytes. Experimental and therapeutic medicine. vol 14. issue 1. 2020-09-30. PMID:28672998. |
cell viability, apoptosis rate and cell migration were examined, and the expression levels of angpt2, glucose transporter 1 (glut1) and caspase-3 were measured by quantitative polymerase chain reaction (qpcr) and western blot analyses. |
2020-09-30 |
2023-08-13 |
Not clear |
| Ying Yanqin, Tang Jing, Chen Wei, Li Na. Grifolin Attenuates White Matter Lesion in Oxygen/Glucose Deprivation. Translational neuroscience. vol 8. 2020-09-30. PMID:29071135. |
whereas immunocytochemistry was performed for the assessment of survival and apoptosis of opcs, western blot assay and rt-pcr were performed after 8th day of ogd injury for the estimation of expressions of myelin basic protein (mbp) and inhibitor of dna binding 2 (id2) in opcs respectively. |
2020-09-30 |
2023-08-13 |
Not clear |
| Wei Yao, Neng Wang, Jin Qian, Lu Bai, Xiaoxin Zheng, Guo Hou, Xuan Qiu, Bo Yan. Renal sympathetic denervation improves myocardial apoptosis in rats with isoproterenol-induced heart failure by downregulation of tumor necrosis factor-α and nuclear factor-κB. Experimental and therapeutic medicine. vol 14. issue 5. 2020-09-30. PMID:29104628. |
the expression of factors associated with myocardial apoptosis, including p53, tumor necrosis factor-α (tnf-α), nuclear factor-κb (nf-κb), caspase-2 and -3, were measured using quantitative polymerase chain reaction and western blot analysis. |
2020-09-30 |
2023-08-13 |
human |