| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huan Wang, Xiaoli Zhu, Jing Huang, Pingsheng Chen, Shuhua Han, Xing Ya. Nedaplatin sensitization of cisplatin-resistant human non-small cell lung cancer cells. Oncology letters. vol 11. issue 4. 2020-10-01. PMID:27073518. |
furthermore, western blot analysis indicated that ndp decreased the protein expression of p-glycoprotein, tumor protein p53 and b-cell lymphoma 2, and increased the expression of bcl-2-associated x protein, all of which could possibly improve the ndp intracellular drug concentration and promote cell apoptosis. |
2020-10-01 |
2023-08-13 |
human |
| Peiyan Hua, Guangxin Zhang, Yifan Zhang, Mei Sun, Ranji Cui, Xin Li, Bingjin Li, Xingyi Zhan. Costunolide induces G1/S phase arrest and activates mitochondrial-mediated apoptotic pathways in SK-MES 1 human lung squamous carcinoma cells. Oncology letters. vol 11. issue 4. 2020-10-01. PMID:27073552. |
through upregulation in the expression of p53 and bax, and downregulation in the expression of bcl-2 and activation of caspase-3, costunolide-induced apoptosis was confirmed by western blot analysis. |
2020-10-01 |
2023-08-13 |
human |
| Shao-Jun Chen, Jian-Hai Lin, Xu-Dong Yao, Bo Peng, Yun-Fei Xu, Min Liu, Jun-Hua Zhen. Nrdp1-mediated degradation of BRUCE decreases cell viability and induces apoptosis in human 786-O renal cell carcinoma cells. Experimental and therapeutic medicine. vol 12. issue 2. 2020-10-01. PMID:27446249. |
western blot analyses of tissue samples from 24 patients with primary rcc revealed lower nrdp1 and higher baculovirus inhibitor of apoptosis repeat-containing ubiquitin-conjugating enzyme (bruce) protein levels in rcc tissues compared with adjacent normal tissues. |
2020-10-01 |
2023-08-13 |
human |
| Tao Jin, Hongyan Wu, Yanlin Wang, Hao Pen. Capsaicin induces immunogenic cell death in human osteosarcoma cells. Experimental and therapeutic medicine. vol 12. issue 2. 2020-10-01. PMID:27446273. |
mitochondrial membrane potential and western blot analysis were used to investigate capsaicin- and cisplatin-induced apoptosis. |
2020-10-01 |
2023-08-13 |
human |
| Shibing Wang, Jing Shu, Li Chen, Xiaopan Chen, Jianhong Zhao, Shuangshuang Li, Xiaozhou Mou, Xiangmin Ton. Synergistic suppression effect on tumor growth of ovarian cancer by combining cisplatin with a manganese superoxide dismutase-armed oncolytic adenovirus. OncoTargets and therapy. vol 9. 2020-10-01. PMID:27799786. |
apoptosis induction by treatment with zd55-mnsod and/or cisplatin was detected in skov-3 by apoptotic cell staining, flow cytometry, and western blot analysis. |
2020-10-01 |
2023-08-13 |
human |
| Xueqiong Lin, Xianhui Liu, Yusen Fang, Xuefen Wen. LIM and SH3 protein 1 promotes tumor proliferation and metastasis in lung carcinoma. Oncology letters. vol 12. issue 6. 2020-10-01. PMID:28105185. |
we determined the expression level of lasp-1 in lung cancer using reverse transcription-quantitative polymerase chain reaction and western blot analysis, and also studied the potential function of lasp-1 in lung cancer cell growth, apoptosis and migration by small interfering rna transfection. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jiaxin Li, Xuping Mao, Xing Wang, Ganggang Miao, Jiaxin L. miR-433 reduces cell viability and promotes cell apoptosis by regulating MACC1 in colorectal cancer. Oncology letters. vol 13. issue 1. 2020-10-01. PMID:28123526. |
furthermore, flow cytometry and mtt assays were used to examine the apoptosis, cell cycle distribution and viability of human colorectal cancer cells, and luciferase reporter and western blot assays were performed to verify the regulatory mechanism of mir-433 on macc1. |
2020-10-01 |
2023-08-13 |
human |
| Bo Chen, Yaoxi Tan, Yan Liang, Yan Li, Lei Chen, Shuangshuang Wu, Wei Xu, Yan Wang, Weihong Zhao, Jianqing W. Per2 participates in AKT-mediated drug resistance in A549/DDP lung adenocarcinoma cells. Oncology letters. vol 13. issue 1. 2020-10-01. PMID:28123577. |
per2 knockdown and overexpression in a549/ddp cells were used to compare cell proliferation (by mtt assay), apoptosis (active-caspase 3 western blot) and clone forming assay. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xinge Shi, Hui Ye, Xuedong Yao, Yanzheng Ga. The involvement and possible mechanism of NR4A1 in chondrocyte apoptosis during osteoarthritis. American journal of translational research. vol 9. issue 2. 2020-10-01. PMID:28337303. |
nr4a1 expression by qrt-pcr and western blot, and chondrocyte apoptosis by tunel assay were detected in normal and oa joint cartilage. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ke Mao, Chao You, Ding Lei, Heng Zhan. Potential regulation of glioma through the induction of apoptosis signaling via Egl-9 family hypoxia-inducible factor 3. Oncology letters. vol 13. issue 2. 2020-10-01. PMID:28356975. |
through the use of immunohistochemical and western blot analyses, it was demonstrated that egln3 expression in glioma tissue performed an important role in regulation by amplifying the signals for apoptosis, as determined by an increase in dna fragments. |
2020-10-01 |
2023-08-13 |
mouse |
| Rima Manafi Shabestari, Majid Safa, Mehdi Banan, Ahmad Kazem. Cyclic AMP-Induced p53 Destabilization is Independent of CREB in Pre-B Acute Lymphoblastic Leukemia Cells. International journal of molecular and cellular medicine. vol 5. issue 4. 2020-10-01. PMID:28357198. |
p53 protein level and apoptosis were assessed by western blot analysis and flow cytometry, respectively. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jie Lin, Li Jing, Hao Zhu, Fu-Sheng Don. Fundamental research on the action mechanism of the 800 nm semiconductor laser on skin blackheads and coarse pores. Experimental and therapeutic medicine. vol 13. issue 1. 2020-10-01. PMID:28428827. |
samples were extracted 1, 7 and 14 days after surgery and hematoxylin and eosin staining was used to identify the following: epidermis, dermis, sebaceous gland change and hair follicle damage; the expression of proliferating cell nuclear antigen (pcna) of sebaceous gland cells using immunohistochemistry; sebaceous gland cell apoptosis using tunel; and the protein expression of caspase-3, bax and bcl-2 using western blot analysis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xiaolin Lin, Lei Tian, Lisha Wang, Wenyan Li, Qi Xu, Xiuying Xia. Antitumor effects and the underlying mechanism of licochalcone A combined with 5-fluorouracil in gastric cancer cells. Oncology letters. vol 13. issue 3. 2020-10-01. PMID:28454311. |
the effects of lca alone or in combination with 5-fu on sgc7901 and mkn-45 gastric cancer cell lines were studied using cell counting kit-8, cell cycle, apoptosis and western blot analyses of cell check points and apoptosis-associated proteins. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ying Wang, Shoujun Yuan, Linna Li, Dexuan Yang, Chengwang Xu, Shanshan Wang, Danshen Zhan. Novel proapoptotic agent SM-1 enhances the inhibitory effect of 5-fluorouracil on colorectal cancer cells Oncology letters. vol 13. issue 6. 2020-10-01. PMID:28599477. |
the reverse transcription-quantitative polymerase chain reaction (rt-qpcr) and western blot analysis revealed the downregulation of b-cell lymphoma 2 and survivin, and the upregulation of apoptosis regulator bcl-2-associated x protein and cleaved poly (adp-ribose) polymerase in hct116 and lovo cells. |
2020-10-01 |
2023-08-13 |
mouse |
| Deyou Wang, Sifeng Tang, Qiwen Zhan. Maslinic acid suppresses the growth of human gastric cells by inducing apoptosis via inhibition of the interleukin-6 mediated Janus kinase/signal transducer and activator of transcription 3 signaling pathway. Oncology letters. vol 13. issue 6. 2020-10-01. PMID:28599489. |
western blot analysis was performed in order to determine the differential expression levels of janus kinase (jak), signal transducer and activator of transcription 3 (stat3) and apoptosis associated proteins b-cell lymphoma 2 (bcl-2), bcl-2 associated x protein (bax) and bcl-2 associated agonist of cell death (bad). |
2020-10-01 |
2023-08-13 |
human |
| Yi Xiao, Taoran Deng, Changliang Su, Zhen Shan. MicroRNA 217 inhibits cell proliferation and enhances chemosensitivity to doxorubicin in acute myeloid leukemia by targeting KRAS. Oncology letters. vol 13. issue 6. 2020-10-01. PMID:28599501. |
following transfection with mir-217 mimics, an mtt assay, chemosensitivity assay, cell apoptosis assay and western blot analysis were performed in aml cell lines. |
2020-10-01 |
2023-08-13 |
rat |
| Hong-Yan Zhang, Wei Yang, Ji-Bin L. Knockdown of GluA2 induces apoptosis in non-small-cell lung cancer A549 cells through the p53 signaling pathway. Oncology letters. vol 14. issue 1. 2020-10-01. PMID:28693266. |
using the cell counting kit-8 assay, western blot analysis and acridine orange/ethidium bromide staining, downregulation of glua2 was revealed to significantly inhibit the proliferation and significantly promote the apoptosis of a549 cells. |
2020-10-01 |
2023-08-13 |
human |
| Jing Shi, Xu Zhang, Taoping Shi, Hongzhao L. Antitumor effects of curcumin in human bladder cancer Oncology letters. vol 14. issue 1. 2020-10-01. PMID:28693289. |
in the present study, the effects of curcumin on cell growth, apoptosis and migration of bladder cancer cell lines were evaluated using an mtt assay, a transwell assay and flow cytometry, and the associated mechanisms were investigated using western blot analysis. |
2020-10-01 |
2023-08-13 |
human |
| Zhongwei He, Xiangling Xiao, Shan Li, Yang Guo, Qiuyue Huang, Xin Shi, Xiaobo Wang, Ying Li. Oridonin induces apoptosis and reverses drug resistance in cisplatin resistant human gastric cancer cells. Oncology letters. vol 14. issue 2. 2020-10-01. PMID:28781688. |
the drug sensitivity, cell apoptosis and effects on mdr were detected by mtt assay and western blot analysis. |
2020-10-01 |
2023-08-13 |
human |
| Dafei Xie, Peiwen Yuan, Dong Wang, Hua Jin, Hui Che. Effects of naringin on the expression of miR-19b and cell apoptosis in human hepatocellular carcinoma. Oncology letters. vol 14. issue 2. 2020-10-01. PMID:28789364. |
the effects of naringin on the proliferation of hepg2 cells were observed by an mtt assay, morphological changes of cells were observed by an inverted microscope, cell apoptosis was detected by dapi staining, mir-19b mrna levels were determined with rt-pcr, and the expression of bax and bcl-2 proteins was examined by western blot assay. |
2020-10-01 |
2023-08-13 |
human |