| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiangyu Cao, Mingyang Fu, Ruochen Bi, Xiaomei Zheng, Baorong Fu, Siqi Tian, Chengying Liu, Qijiu Li, Jianli Li. Cadmium induced BEAS-2B cells apoptosis and mitochondria damage via MAPK signaling pathway. Chemosphere. vol 263. 2020-12-21. PMID:33297271. |
cell viability, mitochondrial membrane potential, reactive oxygen species (ros) level, apoptosis and the related signaling pathways were detected with mtt assay, rhodamine staining, dcfh-da staining, hoechst33258 staining and western blot methods respectively. |
2020-12-21 |
2023-08-13 |
human |
| Xiaohui Li, Xingtao Han, Pengtao Wei, Jinhui Yang, Jiantao Su. Knockdown of lncRNA CCAT1 enhances sensitivity of paclitaxel in prostate cancer via regulating miR-24-3p and FSCN1. Cancer biology & therapy. vol 21. issue 5. 2020-12-16. PMID:32089062. |
the viability and apoptosis were detected by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide assay, flow cytometry and western blot, respectively. |
2020-12-16 |
2023-08-13 |
human |
| Yakun Wang, Yinghui Qi, Tingting Ji, Bo Tang, Xiaoying Li, Pengxi Zheng, Shoujun Ba. Circ_LARP4 regulates high glucose-induced cell proliferation, apoptosis, and fibrosis in mouse mesangial cells. Gene. vol 765. 2020-12-16. PMID:32891769. |
as measured by western blot, circ_larp4 overexpression enhanced bax expression but reduced bcl-2 expression, also suggesting an enhancement of cell apoptosis. |
2020-12-16 |
2023-08-13 |
mouse |
| Yuji Nozaki, Jinhai Ri, Kenji Sakai, Kaoru Niki, Masanori Funauchi, Itaru Matsumur. Protective Effects of Recombinant Human Soluble Thrombomodulin on Lipopolysaccharide-Induced Acute Kidney Injury. International journal of molecular sciences. vol 21. issue 7. 2020-12-15. PMID:32260474. |
cell activation and apoptosis signal was assessed by western blot analysis. |
2020-12-15 |
2023-08-13 |
mouse |
| J Li, A Sheng Wang, S Wang, C Yong Wang, S Xue, W Yong Li, T Tu Ma, Y Xi Sha. Death-inducer obliterator 1 (DIDO1) silencing suppresses growth of bladder cancer cells through decreasing SAPK/JNK signaling cascades. Neoplasma. vol 67. issue 5. 2020-12-15. PMID:32484699. |
furthermore, we identified signaling molecules involved in stress and apoptosis using the pathscan antibody array kit and western blot. |
2020-12-15 |
2023-08-13 |
mouse |
| Z Y Xian, B Hu, T Wang, J L Cai, J Y Zeng, Q Zou, P X Zh. CircABCB10 silencing inhibits the cell ferroptosis and apoptosis by regulating the miR-326/CCL5 axis in rectal cancer. Neoplasma. vol 67. issue 5. 2020-12-15. PMID:32567935. |
the expression of circabcb10, microrna (mir)-326 and c-c motif chemokine ligand 5 (ccl5), and apoptosis related-protein was detected using quantitative real-time polymerase chain reaction or western blot, respectively. |
2020-12-15 |
2023-08-13 |
Not clear |
| Lijing Li, Penghua Cui, Huimin Ge, Yanjing Shi, Xiaoguang Wu, Zhang Fan R. miR-188-5p inhibits apoptosis of neuronal cells during oxygen-glucose deprivation (OGD)-induced stroke by suppressing PTEN. Experimental and molecular pathology. vol 116. 2020-12-15. PMID:32745469. |
both western blot as well as rt-qpcr found the proliferation biomarkers such as ki87 and pcna in addition to apoptosis biomarkers such as caspase-8 and caspase-3. |
2020-12-15 |
2023-08-13 |
human |
| Shanky Garg, Sana Irfan Khan, Rajiv Kumar Malhotra, Manish Kumar Sharma, Manoj Kumar, Punit Kaur, Tapas Chandra Nag, RumaRay, Jagriti Bhatia, Dharamvir Singh Ary. The molecular mechanism involved in cardioprotection by the dietary flavonoid fisetin as an agonist of PPAR-γ in a murine model of myocardial infarction. Archives of biochemistry and biophysics. vol 694. 2020-12-15. PMID:32926843. |
fisetin pretreatment upregulated the expression of ppar-γ in heart tissue significantly cardioprotection was assessed by measurement of hemodynamic parameters, infarct size, elisa for oxidative stress, immunohistochemistry and tunel assay for apoptosis, and western blot analysis for mapk proteins and inflammation. |
2020-12-15 |
2023-08-13 |
rat |
| Cheng Luo, Xiaoyong Xie, Xu Feng, Binfeng Lei, Chen Fang, Yugui Li, Xiongwei Cai, Guoxing Ling, Baoshi Zhen. Deficiency of Interleukin-36 Receptor Protected Cardiomyocytes from Ischemia-Reperfusion Injury in Cardiopulmonary Bypass. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-12-14. PMID:32048631. |
tunel staining and western blot analyses found that cardiomyocyte apoptosis and inflammation were significantly lower in the hearts of il-36r-/- rats compared with that of wt rats. |
2020-12-14 |
2023-08-13 |
rat |
| Jing Zhao, Kai Zhou, Liang Ma, Huanyu Zhan. MicroRNA-145 overexpression inhibits neuroblastoma tumorigenesis Bioengineered. vol 11. issue 1. 2020-12-14. PMID:32083506. |
the effect of mir-145 on cell viability was evaluated using mtt assays, apoptosis levels were determined using tunel staining, and the mtdh protein expression was determined using western blot and rt-pcr. |
2020-12-14 |
2023-08-13 |
Not clear |
| Li Xiong, Yingying Gong, Liting Wu, Jin Li, Weiman He, Xiaonan Zhu, Haipeng Xia. LncRNA-Malat1 is Involved in Lipotoxicity-Induced ß-cell Dysfunction and the Therapeutic Effect of Exendin-4 via Ptbp1. Endocrinology. vol 161. issue 7. 2020-12-14. PMID:32324218. |
the results of tunel, western blot and flow cytometric analyses, and gsis assays revealed that malat1 knockdown significantly induced β-cell apoptosis and inhibited insulin secretion. |
2020-12-14 |
2023-08-13 |
mouse |
| Naze G Avci, Sadaf Ebrahimzadeh-Pustchi, Yasemin M Akay, Yoshua Esquenazi, Nitin Tandon, Jay-Jiguang Zhu, Metin Aka. NF-κB inhibitor with Temozolomide results in significant apoptosis in glioblastoma via the NF-κB(p65) and actin cytoskeleton regulatory pathways. Scientific reports. vol 10. issue 1. 2020-12-14. PMID:32770097. |
gbm cells and patient-derived gbm cells cultured in 3d microwells were co-treated with bay 11-7082 and tmz or bay 11-7082 and tmz alone, and combined experiments of cell proliferation, apoptosis, wound healing assay, as well as reverse-phase protein arrays, western blot and immunofluorescence staining were used to evaluate the effects of drugs on gbm cells. |
2020-12-14 |
2023-08-13 |
Not clear |
| Xiaowei Wang, Jing Tong, Xiaodi Han, Xiaoming Qi, Jun Zhang, Erxi Wu, Jason H Huan. Acute effects of human protein S administration after traumatic brain injury in mice. Neural regeneration research. vol 15. issue 11. 2020-12-12. PMID:32394965. |
immunohistochemistry and western blot targeting caspase-3, b-cell lymphoma 2 (bcl-2) along with terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) assay revealed that apoptosis was suppressed in treated animals. |
2020-12-12 |
2023-08-13 |
mouse |
| XinHong Xue, HongRu Wang, JiangLi S. Inhibition of MiR-122 Decreases Cerebral Ischemia-reperfusion Injury by Upregulating DJ-1-Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN)/Phosphonosinol-3 Kinase (PI3K)/AKT. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-12-11. PMID:32061171. |
flow cytometry was used to detect apoptosis and western blot was used to detect the expression of dj-1, pten, akt, and p-akt. |
2020-12-11 |
2023-08-13 |
rat |
| Zhuoran Wang, Yuqiao Yang, Wei Xiong, Rui Zhou, Ning Song, Lan Liu, Jinqiao Qia. Dexmedetomidine protects H9C2 against hypoxia/reoxygenation injury through miR-208b-3p/Med13/Wnt signaling pathway axis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 125. 2020-12-10. PMID:32070878. |
cck8 and, flow cytometry and western blot were conducted respectively to examine viability, apoptosis rate and protein expressions of h9c2 subjected to a variety of treatments. |
2020-12-10 |
2023-08-13 |
Not clear |
| Yinlian Cai, Ling Xu, Chaoxiang Xu, Yaoguo Wang, Chenghui Fa. Hsa_circ_0001445 inhibits ox-LDL-induced HUVECs inflammation, oxidative stress and apoptosis by regulating miRNA-640. Perfusion. 2020-12-10. PMID:33300444. |
flow cytometry assay was applied to measure cell apoptosis, and the expressions of apoptosis-related protein were measured by western blot. |
2020-12-10 |
2023-08-13 |
Not clear |
| Elham Ramazani, Mahdi YazdFazeli, Seyed Ahmad Emami, Leila Mohtashami, Behjat Javadi, Javad Asili, Zahra Tayarani-Najara. Protective effects of Cinnamomum verum, Cinnamomum cassia and cinnamaldehyde against 6-OHDA-induced apoptosis in PC12 cells. Molecular biology reports. vol 47. issue 4. 2020-12-08. PMID:32166553. |
cell viability and apoptosis were assessed using resazurin assay, flow cytometry of propidium iodide (pi) stained cells, and western blot analysis. |
2020-12-08 |
2023-08-13 |
Not clear |
| Xiuyun Lu, Yanhui Yu, Fengxiang Yin, Chuandong Yang, Bing Li, Jing Lin, Huimin Y. Knockdown of PVT1 inhibits IL-1β-induced injury in chondrocytes by regulating miR-27b-3p/TRAF3 axis. International immunopharmacology. vol 79. 2020-12-07. PMID:31863917. |
il-1β-induced injury was investigated by cell viability, apoptosis, autophagy and inflammatory response using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-h-tetrazolium bromide, flow cytometry, western blot and enzyme linked immunosorbent assay, respectively. |
2020-12-07 |
2023-08-13 |
human |
| Jiqin Wang, Jianfeng Song, Yanyan Li, Jinyan Shao, Zichen Xie, Keyu Su. Down-regulation of LncRNA CRNDE aggravates kidney injury via increasing MiR-181a-5p in sepsis. International immunopharmacology. vol 79. 2020-12-07. PMID:31877497. |
peroxisome proliferator-activated receptor-α (pparα) and cell apoptosis related molecules were detected by western blot. |
2020-12-07 |
2023-08-13 |
rat |
| Paksiree Saranaruk, Ryusho Kariya, Gunya Sittithumcharee, Parichart Boueroy, Thidarut Boonmars, Kanlayanee Sawanyawisuth, Chaisiri Wongkham, Sopit Wongkham, Seiji Okada, Kulthida Vaeteewoottachar. Chromomycin A3 suppresses cholangiocarcinoma growth by induction of S phase cell cycle arrest and suppression of Sp1‑related anti‑apoptotic proteins. International journal of molecular medicine. vol 45. issue 4. 2020-11-30. PMID:32124934. |
the effects of cma3 on anti‑proliferation, cell cycle arrest and apoptosis induction in cca cells were demonstrated by mtt assay, flow cytometry and western blot analysis. |
2020-11-30 |
2023-08-13 |
mouse |