| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Guo, Yuanyuan Song, Wantong Song, Yingmin Liu, Zhihe Liu, Dawei Zhang, Zhaohui Tang, Ou Ba. Co-delivery of Doxorubicin and Curcumin with Polypeptide Nanocarrier for Synergistic Lymphoma Therapy. Scientific reports. vol 10. issue 1. 2020-11-30. PMID:32398729. |
the cell apoptosis and the possible mechanisms of apoptosis pathways regulation by l-dox + cur were examined using flow cytometry and western blot. |
2020-11-30 |
2023-08-13 |
mouse |
| Zhan Gao, Qiang Gao, Xiaodong L. MicroRNA-668-3p Protects Against Oxygen-Glucose Deprivation in a Rat H9c2 Cardiomyocyte Model of Ischemia-Reperfusion Injury by Targeting the Stromal Cell-Derived Factor-1 (SDF-1)/CXCR4 Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-11-24. PMID:31997826. |
protein and mrna levels of sdf-1, cxcr4, bcl2, bax, cleaved caspase-3, endothelial nitric oxide synthase (enos), and phosphorylated endothelial nitric oxide synthase (p-enos) were analyzed by western blot and quantitative reverse transcription-polymerase chain reaction (rt-qpcr), and apoptosis were assessed by flow cytometry. |
2020-11-24 |
2023-08-13 |
rat |
| Chunhui Zhang, Suyan Chen, Zhenxiang Zhang, Hui Xu, Weihong Zhang, Dongqing Xu, Beilei Lin, Yongxia Me. Asiaticoside Alleviates Cerebral Ischemia-Reperfusion Injury via NOD2/Mitogen-Activated Protein Kinase (MAPK)/Nuclear Factor kappa B (NF-κB) Signaling Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-11-24. PMID:32006420. |
tunel assay was performed for assessment of cell apoptosis and western blot analysis was performed to assess protein expression levels. |
2020-11-24 |
2023-08-13 |
rat |
| Wanatchaporn Arunmanee, Gea Abigail U Ecoy, Hnin Ei Ei Khine, Methawee Duangkaew, Eakachai Prompetchara, Pithi Chanvorachote, Chatchai Chaotha. Colicin N Mediates Apoptosis and Suppresses Integrin-Modulated Survival in Human Lung Cancer Cells. Molecules (Basel, Switzerland). vol 25. issue 4. 2020-11-23. PMID:32069989. |
the activation of extrinsic apoptosis evidenced with the reduction of c-flip and caspase-8, as well as the modulation of intrinsic apoptosis signaling proteins including bax and mcl-1 were observed via western blot analysis in lung cancer cells cultured with colicin n (10-15 µm) for 12 h. moreover, 5-15 µm of colicin n down-regulated the expression of activated akt (p-akt) and its upstream survival molecules, integrin β1 and αv in human lung cancer cells. |
2020-11-23 |
2023-08-13 |
human |
| Soo-Min Kim, Kyung-Chul Cho. Acrylonitrile induced cell cycle arrest and apoptosis by promoting the formation of reactive oxygen species in human choriocarcinoma cells. The Journal of toxicological sciences. vol 45. issue 11. 2020-11-23. PMID:33132245. |
moreover, western blot assay confirmed that an treatment of jeg-3 and bewo cells for 4 hr promoted the expression of phosphorylated eukaryotic initiation factor 2 alpha protein (p-eif2α), c/ebp homologous protein (chop) and caspase 12, which are known to be involved in ros-mediated endoplasmic reticulum stress (er-stress)-related apoptosis. |
2020-11-23 |
2023-08-13 |
human |
| Yi-Kai Pan, Cheng-Fei Li, Yuan Gao, Yong-Chun Wang, Xi-Qing Su. Effect of miR-27b-5p on apoptosis of human vascular endothelial cells induced by simulated microgravity. Apoptosis : an international journal on programmed cell death. vol 25. issue 1-2. 2020-11-19. PMID:31768842. |
the effects of these mirnas on huvecs apoptosis were evaluated by flow cytometry, western blot and hoechst staining. |
2020-11-19 |
2023-08-13 |
human |
| Lu Guo, Jum Soon Kang, Nam Jun Kang, Young Whan Cho. S-petasin induces apoptosis and inhibits cell migration through activation of p53 pathway signaling in melanoma B16F10 cells and A375 cells. Archives of biochemistry and biophysics. vol 692. 2020-11-19. PMID:32763235. |
s-petasin induced cell apoptosis in b16f10 cells and a375 cells as evidenced by flow cytometry assay and western blot assay. |
2020-11-19 |
2023-08-13 |
Not clear |
| Zhenjie Zhu, Min Ge, Chunlei Li, Liqiang Yu, Yudan Gu, Yuming Hu, Zhilong Ca. Effects of p38 MAPK signaling pathway on cognitive function and recovery of neuronal function after hypoxic-ischemic brain injury in newborn rats. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 78. 2020-11-17. PMID:32360159. |
twenty-four hours after modeling, the expression of p-p38 mapk protein and apoptosis related genes in rat hippocampal tissues was detected by tunel staining, qrt-pcr and western blot. |
2020-11-17 |
2023-08-13 |
rat |
| Jiawei Ye, Hui Dai, Yuqi Liu, Bin Yu, Jiyuan Yang, Aihua Fe. Blockade of C3a/C3aR axis alleviates severe acute pancreatitis-induced intestinal barrier injury. American journal of translational research. vol 12. issue 10. 2020-11-17. PMID:33194030. |
cell apoptosis was evaluated by tunel assay and western blot analysis. |
2020-11-17 |
2023-08-13 |
rat |
| Shunhui Wei, See Wee Low, Charlene Priscilla Poore, Bo Chen, Yahui Gao, Bernd Nilius, Ping Lia. Comparison of Anti-oncotic Effect of TRPM4 Blocking Antibody in Neuron, Astrocyte and Vascular Endothelial Cell Under Hypoxia. Frontiers in cell and developmental biology. vol 8. 2020-11-17. PMID:33195194. |
tunel assay, pi staining and western blot on cleaved caspase-3 revealed that m4p could ameliorate apoptosis after 24 h hypoxia exposure. |
2020-11-17 |
2023-08-13 |
rat |
| C Xu, J Zhai, Y F. LncRNA CDKN2B-AS1 promotes the progression of ovarian cancer by miR-143-3p/SMAD3 axis and predicts a poor prognosis. Neoplasma. vol 67. issue 4. 2020-11-16. PMID:32305052. |
cell apoptosis was assessed by flow cytometry and western blot analyses. |
2020-11-16 |
2023-08-13 |
human |
| Gun He Nam, Kyung-Jo Jo, Ye-Seul Park, Hye Won Kawk, Je-Geun Yoo, Jin Dong Jang, Sang Moon Kang, Sang-Yong Kim, Young-Min Ki. The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression. Scientific reports. vol 9. issue 1. 2020-11-12. PMID:31729428. |
then, a cytotoxicity assay, flow cytometry, western blot, immunoprecipitation, and 3d cell culture for immunohistochemistry were conducted to investigate the mtorc1 pathway and suppression of autophagy and apoptosis. |
2020-11-12 |
2023-08-13 |
human |
| Vanessa S Y Tay, Surabhi Devaraj, Tracy Koh, Guo Ke, Karen C Crasta, Yusuf Al. Increased double strand breaks in diabetic β-cells with a p21 response that limits apoptosis. Scientific reports. vol 9. issue 1. 2020-11-09. PMID:31852915. |
western blot analysis revealed increased cleaved caspase3 over time, suggesting higher frequency of apoptosis due to dox-induced dna strand breaks. |
2020-11-09 |
2023-08-13 |
mouse |
| Chunfang Gan, Xiaotong Huang, Yulan Wu, Junyan Zhan, Xuehong Zhang, Qinzhou Liu, Yanmin Huan. Untargeted metabolomics study and pro-apoptotic properties of B-norcholesteryl benzimidazole compounds in ovarian cancer SKOV3 cells. The Journal of steroid biochemistry and molecular biology. vol 202. 2020-11-04. PMID:32535031. |
western blot results showed that b-norcholesteryl benzimidazole compounds (1 and 2) induced apoptosis in skov3 cells via activation of the mitochondrial signaling pathway. |
2020-11-04 |
2023-08-13 |
human |
| Q H Pan, Y H Fan, Y Z Wang, D M Li, C E Hu, R X L. Long noncoding RNA NNT-AS1 functions as an oncogene in breast cancer via repressing ZFP36 expression. Journal of biological regulators and homeostatic agents. vol 34. issue 3. 2020-11-03. PMID:32691576. |
cell counting kit-8 assay (cck-8), colony formation assay, cell cycle analysis, cell apoptosis analysis, cound healing assay, transwell assay, cioinformatics analysis, western blot analysis and xenograft model were used. |
2020-11-03 |
2023-08-13 |
human |
| Jianhong Guo, Yinhuan Ding, Hongbo Yang, Hao Guo, Xin Zhou, Xiao Che. Aberrant expression of lncRNA MALAT1 modulates radioresistance in colorectal cancer in vitro via miR-101-3p sponging. Experimental and molecular pathology. vol 115. 2020-10-29. PMID:32380053. |
cell transfection upregulated or silenced genes in crc-ir cells so as to study the correlation between malat1/mir-101-3p expression and cellular resistance to irradiation through evaluation of cck-8, fcm apoptosis, transwell migration and invasion and western blot assays for cell viability,apoptosis, migration and invasion and emt. |
2020-10-29 |
2023-08-13 |
human |
| Rosemary A Poku, Kylee J Jones, Megan Van Baren, Jamie K Alan, Felix Amissa. Diclofenac Enhances Docosahexaenoic Acid-Induced Apoptosis in Vitro in Lung Cancer Cells. Cancers. vol 12. issue 9. 2020-10-28. PMID:32962236. |
we further conducted cell apoptosis assays and analyzed apoptosis-associated proteins and some key proteins in the ras/mek/erk and pi3k/akt pathways using western blot analysis. |
2020-10-28 |
2023-08-13 |
Not clear |
| Rui Zhou, Jun Sun, Chunping He, Chao Huang, Honggang Y. CCL19 suppresses gastric cancer cell proliferation, migration, and invasion through the CCL19/CCR7/AIM2 pathway. Human cell. vol 33. issue 4. 2020-10-27. PMID:32564199. |
apoptosis and inflammation-related biomarkers were detected by western blot and elisa assay. |
2020-10-27 |
2023-08-13 |
mouse |
| Jiandong Sun, Yilin Wang, Lirong Su. INNO-406 inhibits the growth of chronic myeloid leukemia and promotes its apoptosis via targeting PTEN. Human cell. vol 33. issue 4. 2020-10-27. PMID:32862368. |
cell apoptosis were detected by western blot and flow cytometry, respectively. |
2020-10-27 |
2023-08-13 |
Not clear |
| Beyza Goncu, Ece Sevgi, Cagla Kizilarslan Hancer, Guzin Gokay, Nur Ozte. Differential anti-proliferative and apoptotic effects of lichen species on human prostate carcinoma cells. PloS one. vol 15. issue 9. 2020-10-26. PMID:32997661. |
lichen extracts were performed by ethanol, methanol, and acetone separately by using the soxhlet apparatus and the effects of the extracts on cell viability, proliferation, and apoptosis were measured with the utilization of mtt, ldh assay, annexin v assay, and western blot. |
2020-10-26 |
2023-08-13 |
human |