| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luyan Tang, Jian Li, Wenwen Fu, Wenyu Wu, Jinhua X. Suppression of FADS1 induces ROS generation, cell cycle arrest, and apoptosis in melanocytes: implications for vitiligo. Aging. vol 11. issue 24. 2020-10-21. PMID:31866583. |
in addition, cck-8, immunofluorescence, western blot and flow cytometry assay were used to detect the proliferation and apoptosis in pig1 cells respectively. |
2020-10-21 |
2023-08-13 |
human |
| Qiqi Wang, Qingzhe Zhang, Shanshan Luan, Kaiyin Yang, Mengzhu Zheng, Kezhen Li, Lixia Chen, Hua L. Adapalene inhibits ovarian cancer ES-2 cells growth by targeting glutamic-oxaloacetic transaminase 1. Bioorganic chemistry. vol 93. 2020-10-20. PMID:31605927. |
and it induced the apoptosis of es-2 cells according to western blot and hoechst 33258 straining. |
2020-10-20 |
2023-08-13 |
Not clear |
| Shuangshuang Li, Ping Wei, Biao Zhang, Kechuan Chen, Gengsheng Shi, Zhihu Zhang, Zhongjun D. Apoptosis of lung cells regulated by mitochondrial signal pathway in crotonaldehyde-induced lung injury. Environmental toxicology. vol 35. issue 11. 2020-10-20. PMID:32639093. |
therefore, the aim of the present study is to determine whether crotonaldehyde-induced oxidative damage and inflammation promote apoptosis in rats via the mitochondrial pathway using histopathology, immunohistochemistry, biochemistry analysis and western blot analysis. |
2020-10-20 |
2023-08-13 |
rat |
| Chae Ryeong Ahn, Jinbong Park, Jai-Eun Kim, Kwang Seok Ahn, Young Woo Kim, Minjeong Jeong, Hong Jun Kim, Sun Hyang Park, Seung Ho Bae. Cinnamaldehyde and Hyperthermia Co-Treatment Synergistically Induces ROS-Mediated Apoptosis in ACHN Renal Cell Carcinoma Cells. Biomedicines. vol 8. issue 9. 2020-10-20. PMID:32957430. |
through western blot assays, we observed increased apoptosis signaling and decreased proliferation/metastasis signaling, along with a repressed heat shock protein 70 level. |
2020-10-20 |
2023-08-13 |
Not clear |
| Min Du, Gang Wen, Juan Jin, Yuanguang Chen, Jun Cao, Aman X. Mangiferin prevents the growth of gastric carcinoma by blocking the PI3K-Akt signalling pathway. Anti-cancer drugs. vol 29. issue 2. 2020-10-15. PMID:29215373. |
following treatment, apoptosis rates of sgc-7901 were established by flow cytometry and laser confocal microscopy, and western blot analysis was used to detect the expression of apoptosis-related proteins. |
2020-10-15 |
2023-08-13 |
Not clear |
| Fang Liu, Xiao Di Wan. miR-150-5p represses TP53 tumor suppressor gene to promote proliferation of colon adenocarcinoma. Scientific reports. vol 9. issue 1. 2020-10-15. PMID:31043658. |
furthermore, we used western blot to determine levels of cell cycle regulators with anti-mir-150-5p or apoptosis with overexpression of tp53. |
2020-10-15 |
2023-08-13 |
human |
| Pia Kronschnabl, Arnold Grünweller, Roland K Hartmann, Achim Aigner, Ulrike Weirauc. Inhibition of PIM2 in liver cancer decreases tumor cell proliferation in vitro and in vivo primarily through the modulation of cell cycle progression. International journal of oncology. vol 56. issue 2. 2020-10-15. PMID:31894300. |
using pim2‑specific sirnas, we examined the effects of pim2 knockdown on proliferation (wst‑1 assays and spheroid assays), 3d‑colony formation and colony spread, apoptosis (flow cytometry and caspase 3/caspase 7 activity), as well as cell cycle progression (flow cytometry, rt‑qpcr and western blot analysis) in the two liver cancer cell lines, hepg2 and huh‑7. |
2020-10-15 |
2023-08-13 |
mouse |
| Muhammad Shahid Riaz Rajoka, Haobin Zhao, Hafiza Mahreen Mehwish, Na Li, Yao Lu, Ziyang Lian, Dongyan Shao, Mingliang Jin, Qi Li, Liqing Zhao, Junling Sh. Anti-tumor potential of cell free culture supernatant of Lactobacillus rhamnosus strains isolated from human breast milk. Food research international (Ottawa, Ont.). vol 123. 2020-10-14. PMID:31284979. |
rt-qpcr and western blot analysis showed the induction of apoptosis was achieved via the up-regulation of bad, bax, caspase3, caspase8, caspase9, and down-regulation of bcl-2 genes in hela cells. |
2020-10-14 |
2023-08-13 |
human |
| Mingguo Xu, Qi Qi, Lina Men, Shushui Wang, Meng Li, Min Xiao, Xiaozhou Chen, Sheng Wang, Guobing Wang, Hongling Jia, Cong Li. Berberine protects Kawasaki disease-induced human coronary artery endothelial cells dysfunction by inhibiting of oxidative and endoplasmic reticulum stress. Vascular pharmacology. vol 127. 2020-10-13. PMID:32070767. |
stimulated hcaecs were treated with vehicle (without bbr) and bbr (20 μm) for 24 h, the cell apoptosis, cell cycle, induction of intracellular reactive oxygen species (ros) and protein expression were examined by flow cytometry and western blot. |
2020-10-13 |
2023-08-13 |
human |
| Zihuan Wu, Yan Zhang, Xiarong Gong, Guiguang Cheng, Shibiao Pu, Shengbao Ca. The preventive effect of phenolic-rich extracts from Chinese sumac fruits against nonalcoholic fatty liver disease in rats induced by a high-fat diet. Food & function. vol 11. issue 1. 2020-10-08. PMID:31930271. |
moreover, immunohistochemistry and western blot analyses further revealed that the phenolic-rich extract can improve nafld in high-fat diet induced rats by regulating several key proteins related to lipid metabolism, inflammation and apoptosis of hepatocytes, namely upregulating the expression levels of p-ampk, ppar-α, cpt1 and bcl-2, and downregulating the levels of ppar-γ, cyp2e1, p-p38, p-nf-κb, inos, cox-2, caspase-3d and bax. |
2020-10-08 |
2023-08-13 |
rat |
| Zhiguo Long, Guangjia Feng, Na Zhao, Lei Wu, Hongbo Zh. Isoferulic acid inhibits human leukemia cell growth through induction of G2/M‑phase arrest and inhibition of Akt/mTOR signaling. Molecular medicine reports. vol 21. issue 3. 2020-10-06. PMID:31922221. |
cell apoptosis and apoptosis‑associated signal pathways were analyzed via annexin v/pi staining and western blot assays, respectively. |
2020-10-06 |
2023-08-13 |
human |
| Olga Martinez-Arroyo, Ana Ortega, Javier Perez-Hernandez, Felipe J Chaves, Josep Redon, Raquel Corte. The Rab-Rabphilin system in injured human podocytes stressed by glucose overload and angiotensin II. American journal of physiology. Renal physiology. vol 319. issue 2. 2020-10-06. PMID:32567349. |
apoptosis was analyzed in podocytes, and mrna level quantification, western blot analysis, and immunofluorescence were developed to quantify podocyte-specific molecules and rab-rabphilin components (rab3a, rab27a, and rabphilin3a). |
2020-10-06 |
2023-08-13 |
human |
| Juntao Li, Yan Zhou, Yuting Yan, Zhongnan Zheng, Yabin Hu, Wei W. Sulforaphane-cysteine downregulates CDK4 /CDK6 and inhibits tubulin polymerization contributing to cell cycle arrest and apoptosis in human glioblastoma cells. Aging. vol 12. issue 17. 2020-10-03. PMID:32860670. |
besides, western blot showed that sfn-cys downregulated α-tubulin resulting in microtubule disruption and aggregation, and cell cycle arrest in g2/m phase and apoptosis. |
2020-10-03 |
2023-08-13 |
human |
| Chenjing Zhang, Zhongting Chen, Xinglu Zhou, Wen Xu, Gang Wang, Xiaoxiao Tang, Laisheng Luo, Jiangfeng Tu, Yimiao Zhu, Wen Hu, Xiang Xu, Wensheng Pa. Cantharidin induces G Oncology letters. vol 8. issue 6. 2020-10-01. PMID:25364455. |
mts assays were then employed to examine cellular proliferation, flow cytometry was used to analyze the cell cycle and apoptosis, and western blot analysis was used to determine protein expression levels. |
2020-10-01 |
2023-08-13 |
human |
| Yueran Li, Songshu Xiao, Liu Dan, Min Xu. P16 Oncology letters. vol 9. issue 3. 2020-10-01. PMID:25663864. |
in addition, the proliferation and apoptosis rates of p16 knockdown siha-ddp cells were measured by mtt assay and annexin v flow cytometry and the subsequent changes in cyclin d1 and prb expression were analyzed by western blot analysis. |
2020-10-01 |
2023-08-13 |
human |
| Yunhua Tang, Xiangyang Zhang, Fan Qi, Mingfeng Chen, Yuan Li, Longfei Liu, Wei He, Zhuo Li, Xiongbing Z. Afatinib inhibits proliferation and invasion and promotes apoptosis of the T24 bladder cancer cell line. Experimental and therapeutic medicine. vol 9. issue 5. 2020-10-01. PMID:26136904. |
mtt assay was used to estimate the proliferation of the t24 cells; flow cytometric analysis was used to estimate the effect of afatinib on t24 cell apoptosis; cell invasion ability was assessed by a transwell invasion assay; and western blot analysis was used to detect the expression of bcl-2, bax, akt, extracellular-signal-regulated kinase (erk)1/2, matrix metalloproteinase (mmp)-2 and mmp-9. |
2020-10-01 |
2023-08-13 |
human |
| Erping Yang, Huifeng Zheng, Hao Peng, Yinyuan Din. Lentivirus-induced knockdown of LRP1 induces osteoarthritic-like effects and increases susceptibility to apoptosis in chondrocytes via the nuclear factor-κB pathway. Experimental and therapeutic medicine. vol 10. issue 1. 2020-10-01. PMID:26170918. |
in addition, the effect of lrp1 regulation on growth and apoptosis in chondrocytes was investigated using western blot analysis and a tunel assay. |
2020-10-01 |
2023-08-13 |
Not clear |
| Guangxin Zhang, Mei Sun, Yifan Zhang, Peiyan Hua, Xin Li, Ranji Cui, Xingyi Zhan. Dracorhodin perchlorate induces G Oncology letters. vol 10. issue 1. 2020-10-01. PMID:26171006. |
therefore, the present study aimed to investigate the effects of dp on cell viability, the cell cycle and apoptosis, using an mtt assay, flow cytometry and western blot studies. |
2020-10-01 |
2023-08-13 |
human |
| L I Ma, Yuan Chang, Long Yu, Wenbo He, Yueping Li. Pro-apoptotic and anti-proliferative effects of mitofusin-2 via PI3K/Akt signaling in breast cancer cells. Oncology letters. vol 10. issue 6. 2020-10-01. PMID:26788214. |
flow cytometry, immunofluorescence and western blot analyses were used to test the effects of mfn2 on cell cycle distribution and apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kaixiong Tao, Yuping Yin, Qian Shen, Ying Chen, Ruidong Li, Weilong Chang, Jie Bai, Weizhen Liu, Liang Shi, Peng Zhan. Akt inhibitor MK-2206 enhances the effect of cisplatin in gastric cancer cells. Biomedical reports. vol 4. issue 3. 2020-10-01. PMID:26998277. |
using western blot analysis, mk-2206 was shown to significantly suppress the phosphorylation of akt (ser473), however, the expression of total akt remained the same, and the combination treatment also increased the expression of cleaved poly adenosine diphosphate ribose polymerase, which contributed to apoptosis. |
2020-10-01 |
2023-08-13 |
human |