| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wu Zhang, Yuqin Wu, Hong Chen, Dan Yu, Jinfeng Zhao, Jing Che. Neuroprotective effects of SOX5 against ischemic stroke by regulating VEGF/PI3K/AKT pathway. Gene. vol 767. 2021-01-21. PMID:32949698. |
the protein expression of sox5, vegf and apoptosis related proteins were measured by western blot. |
2021-01-21 |
2023-08-13 |
Not clear |
| Pei Liu, Yaotian Hu, Lin Xia, Min DU, Zhensheng H. miR-4417 suppresses keloid fibrosis growth by inhibiting CyclinD1. Journal of biosciences. vol 45. 2021-01-13. PMID:32345773. |
western blot and flow cytometry were performed to evaluate cell apoptosis. |
2021-01-13 |
2023-08-13 |
Not clear |
| Chuan Hu, Yong Zou, Luan-Lian Jin. miR-140-3p inhibits progression of non-small cell lung cancer by targeting Janus kinase 1. Journal of biosciences. vol 45. 2021-01-13. PMID:32345774. |
cell viability, apoptosis, migration and invasion were detected by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-trtrazolium bromide, flow cytometry, western blot or trans-well assay, respectively. |
2021-01-13 |
2023-08-13 |
Not clear |
| Wei Wang, Qingqing Liu, Tianyi Zhang, Lu Chen, Shu Li, Shiwen X. Glyphosate induces lymphocyte cell dysfunction and apoptosis via regulation of miR-203 targeting of PIK3R1 in common carp (Cyprinus carpio L.). Fish & shellfish immunology. vol 101. 2021-01-12. PMID:32217141. |
therefore, acridine orange/ethidium bromide (ao/eb) and flow cytometry were carried out to evaluate apoptosis, and we also detected cyps (cyp1a1, cyp1b1, cyp1c), cytokine secretion (il-1β, il-8, il-10, ifn-γ, tnf-α), inflammatory factors (nf-κb, cox-2), and the expression of mir-203 and the pi3k/akt pathway by rt-pcr and western blot analyses. |
2021-01-12 |
2023-08-13 |
Not clear |
| Yingjie Ni, Jun Gu, Jianyue Wu, Lin Xu, Yunfeng Ru. MGMT-Mediated neuron Apoptosis in Injured Rat Spinal Cord. Tissue & cell. vol 62. 2021-01-11. PMID:32433023. |
to determine mgmt-mediated apoptosis in spinal cord injury, we performed western blot and analyzed the expression change of mgmt with different timepoints. |
2021-01-11 |
2023-08-13 |
rat |
| Yoshifumi Iwagami, Jing Zou, Hongyu Zhang, Kevin Cao, Chengcheng Ji, Miran Kim, Chiung-Kuei Huan. Alcohol-mediated miR-34a modulates hepatocyte growth and apoptosis. Journal of cellular and molecular medicine. 2021-01-09. PMID:29873178. |
real-time quantitative pcr and western blot were used to determine the growth and apoptosis molecular signalling pathways associated with mir-34a. |
2021-01-09 |
2023-08-13 |
human |
| Mengge Chen, Yanpeng Ding, Yuan Ke, Yifei Zeng, Nuomin Liu, Yahua Zhong, Xinying Hua, Zheng Li, Yudi Xiong, Chaoyan Wu, Haijun Y. Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis. Artificial cells, nanomedicine, and biotechnology. vol 48. issue 1. 2021-01-08. PMID:32456481. |
expression of the proteins about invasion and apoptosis was evaluated by western blot. |
2021-01-08 |
2023-08-13 |
human |
| Ming Cui, Wenjia Shen, Weiwei Qin, Xu Wang, Yanhua Li, Fei Xu, Zhenlei Xi. Circular RNA ciRS-7 promotes tube formation in microvascular endothelial cells through downregulation of miR-26a-5p. Journal of biochemical and molecular toxicology. vol 34. issue 5. 2021-01-07. PMID:32053286. |
western blot was applied to examine apoptosis and tube formation-associated protein expression. |
2021-01-07 |
2023-08-13 |
Not clear |
| Yongxiang Xie, Fang Lan, Jie Zhao, Wei Sh. Hirudin improves renal interstitial fibrosis by reducing renal tubule injury and inflammation in unilateral ureteral obstruction (UUO) mice. International immunopharmacology. vol 81. 2021-01-07. PMID:32066115. |
the related proteins of fibrosis, epithelial-mesenchymal transition (emt) and apoptosis were assessed by western blot analysis. |
2021-01-07 |
2023-08-13 |
mouse |
| Yiwen Zhang, Xiaoxia Zhang, Zumin Xing, Shuyi Tang, Hanwen Chen, Zhongqi Zhang, Jiyuan Li, Yalan L. circStrn3 is involved in bone cancer pain regulation in a rat model. Acta biochimica et biophysica Sinica. vol 52. issue 5. 2021-01-07. PMID:32395748. |
western blot analysis suggested that knockdown of circstrn3 could effectively induce walker 256 cell apoptosis. |
2021-01-07 |
2023-08-13 |
rat |
| Liju Luo, Yu Wang, Pengfei Hu, Jiale W. Long Non-Coding RNA Metastasis Associated Lung Adenocarcinoma Transcript 1 (MALAT1) Promotes Hypertension by Modulating the Hsa-miR-124-3p/Nuclear Receptor Subfamily 3, Group C, Member 2 (NR3C2) and Hsa-miR-135a-5p/NR3C2 Axis. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-01-06. PMID:32222724. |
the mechanism for lncrna malat1 modulating the proliferation and apoptosis of huvecs was explored by cell transfection, cell counting kit-8 (cck-8), quantitative real-time polymerase chain reaction (qrt-pcr), western blot, and dual-luciferase reporter assays. |
2021-01-06 |
2023-08-13 |
human |
| Mengyu Xi, Wan He, Bo Li, Jinfeng Zhou, Zhijian Xu, Huiqun Wu, Yong Zhang, Dongliang Song, Liangning Hu, Ye Lu, Wenxuan Bu, Yuanyuan Kong, Gege Chen, Shuaikang Chang, Jumei Shi, Weiliang Zh. Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells. Acta biochimica et biophysica Sinica. vol 52. issue 4. 2021-01-06. PMID:32259210. |
western blot analysis results showed that the expression of caspase-3, caspase-8, caspase-9 and bax was increased, while bcl-2 and bcl-xl levels were decreased, which suggested that dcz0801 inhibited cell proliferation and promoted intrinsic apoptosis. |
2021-01-06 |
2023-08-13 |
mouse |
| Dongfeng Cai, Song Hong, Jin Yang, Peng Sa. The Effects of microRNA-515-5p on the Toll-Like Receptor 4 (TLR4)/JNK Signaling Pathway and WNT1-Inducible-Signaling Pathway Protein 1 (WISP-1) Expression in Rheumatoid Arthritis Fibroblast-Like Synovial (RAFLS) Cells Following Treatment with Receptor Activator of Nuclear Factor-kappa-B Ligand (RANKL). Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-01-06. PMID:32361708. |
cell proliferation, cell apoptosis, the cell cycle, and protein expression were determined using the cell counting kit-8 (cck-8) assay, flow cytometry, western blot, and real-time polymerase chain reaction (rt-pcr). |
2021-01-06 |
2023-08-13 |
Not clear |
| Yajie Zhou, Yanfei Li, Junwei Shen, Jue Li, Xinming L. Abemaciclib induces apoptosis in cardiomyocytes by activating the Hippo signaling pathway. Acta biochimica et biophysica Sinica. vol 52. issue 8. 2021-01-06. PMID:32556311. |
in this study, we used the cell counting kit-8 assay, western blot analysis, flow cytometry, immunostaining, and quantitative polymerase chain reaction to investigate the role of abemaciclib in inducing apoptosis and in inhibiting the viability and proliferation of ac16 human cardiomyocyte cells. |
2021-01-06 |
2023-08-13 |
human |
| Shenyu Wang, Gongyin Zhao, Shujie Zhao, Yusen Qiao, Huilin Yan. The Effects of Interleukin-33 (IL-33) on Osteosarcoma Cell Viability, Apoptosis, and Epithelial-Mesenchymal Transition are Mediated Through the PI3K/AKT Pathway. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-01-05. PMID:32312946. |
the effects of il-33 on human osteosarcoma cell viability, apoptosis, emt, and the signaling pathways were studied using the mtt assay, flow cytometry, qrt-pcr, and western blot. |
2021-01-05 |
2023-08-13 |
human |
| Shengnan Liu, Li Li, Meihui Li, Junjie Zhan. Effect of miR-26b-5p on cis-diamine dichloroplatinum-induced ovarian granulosa cell injury by targeting MAP3K9. In vitro cellular & developmental biology. Animal. vol 56. issue 3. 2020-12-30. PMID:32185607. |
cell counting kit 8 (cck-8) was used to detect cell viability, flow cytometry was used to detect cell apoptosis, quantitative reverse transcription polymerase chain reaction (qrt-pcr) and western blot (wb) were used to analyze the expression of mir-26b-5p, map3k9, cleaved caspase-3, bax, and bcl-2; dual-luciferase reporter assay results further verify the targeting relation between mir-26b-5p and map3k9. |
2020-12-30 |
2023-08-13 |
rat |
| Shasha Yu, Haiyu Ji, Xiaodan Dong, Anjun Liu, Juan Y. FAS/FAS-L-mediated apoptosis and autophagy of SPC-A-1 cells induced by water-soluble polysaccharide from Polygala tenuifolia. International journal of biological macromolecules. vol 150. 2020-12-28. PMID:32027895. |
western blot analysis showed that the expression of proteins was related to apoptosis and autophagy. |
2020-12-28 |
2023-08-13 |
Not clear |
| Na Liu, Xiao-Lu Zhang, Shu-Yuan Jiang, Jing-Hua Shi, Jun-He Cui, Xiao-Lei Liu, Li-Hong Han, Ke-Rui Gong, Shao-Chun Yan, Wei Xie, Chun-Yang Zhang, Guo Sha. Neuroprotective mechanisms of DNA methyltransferase in a mouse hippocampal neuronal cell line after hypoxic preconditioning. Neural regeneration research. vol 15. issue 12. 2020-12-22. PMID:32594061. |
the effects of hypoxic preconditioning on the cell cycle and apoptosis in ht22 cells were examined by western blot assay and flow cytometry. |
2020-12-22 |
2023-08-13 |
mouse |
| Liuqian Yu, Jinfeng Qia. Dihydrotanshinone I Alleviates Spinal Cord Injury via Suppressing Inflammatory Response, Oxidative Stress and Apoptosis in Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-12-21. PMID:32112706. |
tunel assay and western blot analysis were performed to evaluate cell apoptosis. |
2020-12-21 |
2023-08-13 |
rat |
| Xiaoping Wang, Xiaojia Li, Bin Huang, Lili Yang, Kai Chen, Dongdong Zhao, Xiangdong Luo, Yingji Wan. Downregulation of miR-33 Has Protective Effect Against Aβ₂₅₋₃₅-Induced Injury in SH-SH-SY5Y Cells. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2020-12-21. PMID:32119650. |
flow cytometry and western blot assay were conducted to assess cell apoptosis, and western blot assay was used to assess synaptic protein levels. |
2020-12-21 |
2023-08-13 |
Not clear |