| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Zeng, Ze Ting Xing, Mei Yun Tan, Yan Wen Wu, Chun Yuan Zhan. Lidocaine suppresses the malignant behavior of gastric cancer cells via the c-Met/c-Src pathway. Experimental and therapeutic medicine. vol 21. issue 5. 2021-03-23. PMID:33747163. |
in addition, cell apoptosis and the levels of apoptosis-related proteins were determined using tunel and western blot assays, respectively. |
2021-03-23 |
2023-08-13 |
Not clear |
| Mingzhu Yang, L I Wan. MALAT1 knockdown protects from bronchial/tracheal smooth muscle cell injury via regulation of microRNA-133a/ryanodine receptor 2 axis. Journal of biosciences. vol 46. 2021-03-23. PMID:33753579. |
exogenous changes of malat1, ryr2 or mir-133a in b/tsmcs were fulfilled by cell transfection; cell apoptosis was measured by using cell death detection elisa kit and hochest33342; il-6, tnf-α and il-1β level was detected by using corresponding elisa kit; ryanodine receptor 2 (ryr2) mrna and mir-133a level was determined by rt-qpcr; cleaved caspase-3 (c-caspase-3) and ryr2 expression was detected by western blot; luciferase reporter assay was performed to confirm the target regulation of mir-133a on ryr2. |
2021-03-23 |
2023-08-13 |
rat |
| Yanyan Su, Shuwen Yao, Shili Zhao, Jinchun Li, Hongyan L. LncRNA CCAT1 functions as apoptosis inhibitor in podocytes via autophagy inhibition. Journal of cellular biochemistry. vol 121. issue 1. 2021-03-18. PMID:31468575. |
after developed ccat1 overexpression or knockdown, cell viabilities were determined with the cck-8 assay, apoptosis was examined with flow cytometry, the autophagy was observed by western blot. |
2021-03-18 |
2023-08-13 |
mouse |
| Haojie Wu, Tingting Liu, Hong Ho. Knockdown of LINC00657 inhibits ox-LDL-induced endothelial cell injury by regulating miR-30c-5p/Wnt7b/β-catenin. Molecular and cellular biochemistry. vol 472. issue 1-2. 2021-03-17. PMID:32577947. |
cell viability and apoptosis were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide, flow cytometry, and western blot. |
2021-03-17 |
2023-08-13 |
human |
| Zhen-Peng Huang, Hu Qiu, Ke Wang, Wei-Bo Chao, Hao-Bin Zhu, Hang Chen, Yue Liu, Bao-Ping Y. The impact of acute stress disorder on gallbladder interstitial cells of Cajal. Journal of cellular physiology. vol 235. issue 11. 2021-03-16. PMID:32329051. |
immunohistochemistry, terminal deoxynucleotidyl transferase dutp nick end labeling assays were used to determine iccs apoptosis, whereas western blot analysis and reverse-transcription polymerase chain reaction were used to detect changes in the scf/c-kit signaling pathway. |
2021-03-16 |
2023-08-13 |
rabbit |
| Tingting Wu, Xianying Fang, Jiahui Xu, Yan Jiang, Fuliang Cao, Linguo Zha. Synergistic Effects of Ginkgolide B and Protocatechuic Acid on the Treatment of Parkinson's Disease. Molecules (Basel, Switzerland). vol 25. issue 17. 2021-03-16. PMID:32878312. |
the apoptosis was tested via western blot. |
2021-03-16 |
2023-08-13 |
mouse |
| Qixiang Miao, Xueyang Si, Yanjiao Xie, Lei Chen, Zhen Liu, Lei Liu, Xiangfang Tang, Hongfu Zhan. Effects of acute heat stress at different ambient temperature on hepatic redox status in broilers. Poultry science. vol 99. issue 9. 2021-03-12. PMID:32867954. |
then, the hallmarks of hepatocellular antioxidant and apoptosis were measured by qrt-pcr and western blot. |
2021-03-12 |
2023-08-13 |
Not clear |
| Qian Gu, Canhong Zhu, Xi Wu, Lianghuan Peng, Genya Huang, Rong H. Wogonoside promotes apoptosis and ER stress in human gastric cancer cells by regulating the IRE1α pathway. Experimental and therapeutic medicine. vol 21. issue 4. 2021-03-12. PMID:33692842. |
in the present study, cck-8 assay was used to detect the cell viability, annexin v/pi staining was used to detect the cells apoptosis, western blot analysis and real-time pcr analysis was used to detect the endoplasmic reticulum (er) stress in the ags and mkn-45 gastric cancer cell lines. |
2021-03-12 |
2023-08-13 |
human |
| Lu Kong, Yongya Wu, Wangcheng Hu, Lin Liu, Yuying Xue, Geyu Lian. Mechanisms underlying reproductive toxicity induced by nickel nanoparticles identified by comprehensive gene expression analysis in GC-1 spg cells. Environmental pollution (Barking, Essex : 1987). vol 275. 2021-03-10. PMID:33588191. |
the effects of pir-mmu-32362259 on the viability, cycle and apoptosis as well as related protein expression levels of gc-1 cells induced by ni nps were detected using cck8, flow cytometry and western blot assay, respectively. |
2021-03-10 |
2023-08-13 |
mouse |
| Lingzhi Niu, Xin Liu, Jing Zhao, Yuanping Wang, Yanxia Li, Ke Li, Yingjian Sun, Yajuan Zhen. 5‑Nitro‑2‑(3‑phenylpropylamino) benzoic acid induces apoptosis of human lens epithelial cells via reactive oxygen species and endoplasmic reticulum stress through the mitochondrial apoptosis pathway. International journal of molecular medicine. vol 47. issue 4. 2021-03-10. PMID:33604681. |
apoptosis was examined by assessing mitochondrial membrane potential and using a jc‑1 assay kit, and western blot analysis was performed to measure the expression levels of mitochondrial‑dependent apoptosis pathway‑associated proteins. |
2021-03-10 |
2023-08-13 |
human |
| Xichun Wang, Yunjing Jiang, Lei Zhu, Li Cao, Wei Xu, Sajid Ur Rahman, Shibin Feng, Yu Li, Jinjie W. Autophagy protects PC12 cells against deoxynivalenol toxicity via the Class III PI3K/beclin 1/Bcl-2 pathway. Journal of cellular physiology. vol 235. issue 11. 2021-03-08. PMID:31930515. |
the relationship between autophagy and apoptosis was analyzed by western blot analysis and flow cytometry. |
2021-03-08 |
2023-08-13 |
human |
| Yanan Huo, Wei Chen, Xiaoxiao Zheng, Jinchuan Zhao, Qi Zhang, Yuerou Hou, Ying Cai, Xuemei Lu, Xiuming Ji. The protective effect of EGF-activated ROS in human corneal epithelial cells by inducing mitochondrial autophagy via activation TRPM2. Journal of cellular physiology. vol 235. issue 10. 2021-03-08. PMID:32083315. |
cck-8 assays, edu assays, western blot analysis, wound-healing assays, and flow cytometry were conducted to determine cell viability, proliferation, protein expression, cell apoptosis, and intracellular ros levels, respectively. |
2021-03-08 |
2023-08-13 |
human |
| Jierong Mo, Yuwan Zhao, Zhixian Ao, Lixin Chen, Shanhong Lin, Wenfeng Zeng, Haokai Wu, Jianjun Li. Circ-APBB1IP as a Prognostic Biomarker Promotes Clear Cell Renal Cell Carcinoma Progression Through The ERK1/2 Signaling Pathway. International journal of medical sciences. vol 17. issue 9. 2021-03-08. PMID:32547313. |
the function and mechanism of circrna were explored by cell transfection, cell counting kit-8, fluorescein isothiocyanate (fitc) annexin v apoptosis detection, wound healing, transwell, and western blot. |
2021-03-08 |
2023-08-13 |
human |
| Junna He, Xiangjian Zhang, Weiliang He, Yanzhao Xie, Yanxia Chen, Yang Yang, Rong Che. Neuroprotective effects of zonisamide on cerebral ischemia injury via inhibition of neuronal apoptosis. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 54. issue 4. 2021-03-04. PMID:33656055. |
the apoptosis of the cells and expression of apoptosis-related proteins were investigated by flow cytometry and western blot analysis, respectively. |
2021-03-04 |
2023-08-13 |
mouse |
| Jianhong Zhao, Zilong Zhang, Qingfeng Cui, Lina Zhao, Yongjun Hu, Subin Zha. Human adipose-derived mesenchymal stem cells inhibit proliferation and induce apoptosis of human gastric cancer HGC-27 cells. 3 Biotech. vol 10. issue 3. 2021-03-02. PMID:32154042. |
annexin-v/pi assay, western blot, and caspase-3 enzyme activity assay were performed to detect cells apoptosis. |
2021-03-02 |
2023-08-13 |
mouse |
| Kang Chen, Chen Jin, Yu-Yao Cheng, Qing-Xi Zhang, Xun-Xun Li, Ling Zhan. [Molecular mechanism of Spatholobi Caulis in treatment of lung cancer based on network pharmacology and molecular docking]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 4. 2021-03-02. PMID:33645088. |
western blot showed that luteolin, licochalcone a and spatholobi caulis extract could induce cell apoptosis by increasing the expressions of pro-apoptotic factors caspase-3 and bax. |
2021-03-02 |
2023-08-13 |
human |
| Peng Li, Kang Li, Chao Zou, Cui Tong, Lin Sun, Zhongjun Cao, Shuhua Yang, Qiufeng Ly. Selenium Yeast Alleviates Ochratoxin A-Induced Hepatotoxicity via Modulation of the PI3K/AKT and Nrf2/Keap1 Signaling Pathways in Chickens. Toxins. vol 12. issue 3. 2021-03-01. PMID:32106596. |
serum biochemistry analysis, antioxidant analysis, as well as the qrt-pcr and western blot (wb) analyses were then used to evaluate oxidative damage and apoptosis in chicken liver tissue. |
2021-03-01 |
2023-08-13 |
chicken |
| Peng Wu, Sha-Sha Yu, Chao Liu, An-Jun Li. Seleno-Chitosan induces apoptosis of lung cancer cell line SPC-A-1 via Fas/FasL pathway. Bioorganic chemistry. vol 97. 2021-03-01. PMID:32146174. |
western blot showed that seleno-chitosan induced apoptosis via the mitochondrial pathway in spc-a-1. |
2021-03-01 |
2023-08-13 |
human |
| Chen Wang, Xiangmin Lv, Chunbo He, John S Davis, Cheng Wang, Guohua Hu. Four and a Half LIM Domains 2 (FHL2) Contribute to the Epithelial Ovarian Cancer Carcinogenesis. International journal of molecular sciences. vol 21. issue 20. 2021-03-01. PMID:33092075. |
western blot data showed that knockdown of fhl2 downregulated akt expression level, and upregulated apoptosis related proteins such as cleaved parp, and cleaved-lamin a. |
2021-03-01 |
2023-08-13 |
Not clear |
| Chao Li, Liang Shi, Cheng Peng, Gongchang Yu, Yanshu Zhang, Zhongjun D. Lead-induced cardiomyocytes apoptosis by inhibiting gap junction intercellular communication via autophagy activation. Chemico-biological interactions. vol 337. 2021-03-01. PMID:33242459. |
the present study aims to determine whether pb-induced autophagy promotes apoptosis of rat cardiac myocytes (h9c2 cells) by downregulating gjic using cck-8 kit, scrape loading/dye transfer assay, annexin v/pi assays, western blot analysis and double-immunofluorescence experiments. |
2021-03-01 |
2023-08-13 |
rat |