| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammad A Y Alqudah, Hebah T Mansour, Nizar Mhaida. Simvastatin enhances irinotecan-induced apoptosis in prostate cancer via inhibition of MCL-1. Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society. vol 26. issue 2. 2020-10-01. PMID:30166915. |
western blot showed that apoptosis was accompanied by upregulation of grp-78 level and downregulation of mcl-1 levels in a time-dependent manner. |
2020-10-01 |
2023-08-13 |
Not clear |
| Rima Manafi Shabestari, Fatemeh Alikarami, Davood Bashash, Mostafa Paridar, Majid Saf. Overexpression of MiR-138 Inhibits Cell Growth and Induces Caspase-mediated Apoptosis in Acute Promyelocytic Leukemia Cell Line. International journal of molecular and cellular medicine. vol 7. issue 1. 2020-10-01. PMID:30234070. |
for evaluation of apoptosis, annexin-v staining and activation of caspases were assessed using flow cytometry and western blot analysis, respectively. |
2020-10-01 |
2023-08-13 |
Not clear |
| Jeongeun Hyun, Youngjae Lee, Sihyung Wang, Jinnyun Kim, Jieun Kim, JaeHo Cha, Young-Su Seo, Youngmi Jun. Kombucha tea prevents obese mice from developing hepatic steatosis and liver damage. Food science and biotechnology. vol 25. issue 3. 2020-10-01. PMID:30263346. |
immunostaining and western blot assays for active caspase-3 demonstrated a lower level of apoptosis in the mcd+kt than in the mcd group. |
2020-10-01 |
2023-08-13 |
mouse |
| Hui-Li Zhu, Zhang-Pei Liu, Wan-Yong Yang, Da-Wei Dong, Ying Zhao, Bing Yang, Li-An Huang, Yu-Sheng Zhang, An-Ding X. Liraglutide Ameliorates β-Amyloid Deposits and Secondary Damage in the Ipsilateral Thalamus and Sensory Deficits After Focal Cerebral Infarction in Rats. Frontiers in neuroscience. vol 12. 2020-10-01. PMID:30618584. |
terminal deoxynucleotidyl transferase 2'-deoxyuridine 5'-triphosphate nick end labeling and western blot were used to detect neuronal apoptosis. |
2020-10-01 |
2023-08-13 |
rat |
| Xin Jiang, Yanwei Du, Xinxin Meng, Hongmei Zhang, Di Zhao, Lijing Zhao, Junyu Chen, Shengxiang Xiao, Hongyu Jian. Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin. Dose-response : a publication of International Hormesis Society. vol 16. issue 4. 2020-10-01. PMID:30622447. |
the histology of tumor tissue was observed by hematoxylin and eosin staining, the apoptosis was determined by terminal deoxynucleotidyl transferase-mediated dutp nick-end labeling, and the expression of ki67, bcl-2, bax, cleaved caspase3, matrix metalloproteinase 2 (mmp2), mmp9, and cd34 was detected by western blot. |
2020-10-01 |
2023-08-13 |
mouse |
| Wenting Zhang, Aiguo Men. MicroRNA-124 expression in the brains of rats during early cerebral ischemia and reperfusion injury is associated with cell apoptosis involving STAT3. Experimental and therapeutic medicine. vol 17. issue 4. 2020-10-01. PMID:30906474. |
to elucidate the association between the dynamic expression of microrna-124 and apoptosis, the expression of proteins associated with apoptosis, including caspase-3, apoptosis regulator bcl-2 (bcl-2) and apoptosis regulator bax (bax) was analyzed by immunohistochemistry and western blot analyses. |
2020-10-01 |
2023-08-13 |
rat |
| Wenting Zhang, Aiguo Men. MicroRNA-124 expression in the brains of rats during early cerebral ischemia and reperfusion injury is associated with cell apoptosis involving STAT3. Experimental and therapeutic medicine. vol 17. issue 4. 2020-10-01. PMID:30906474. |
as signal transducer and activator of transcription 3 (stat3) is involved in cell apoptosis and associated with bcl-2, the protein expression of stat3 and its active form, phosphorylated (p-)stat3, were analyzed by western blot analysis. |
2020-10-01 |
2023-08-13 |
rat |
| Xiaoying Gao, Mian Guo, Dawei Meng, Feixiang Sun, Lianyue Guan, Ying Cui, Yan Zhao, Xichun Wang, Xin Gu, Jiahang Sun, Sihua Q. Silencing MicroRNA-134 Alleviates Hippocampal Damage and Occurrence of Spontaneous Seizures After Intraventricular Kainic Acid-Induced Status Epilepticus in Rats. Frontiers in cellular neuroscience. vol 13. 2020-10-01. PMID:31031600. |
western blot showed that a mir-134 antagonist suppressed lesion-induced endoplasmic reticulum (er) stress and apoptosis related expression of chop, bim and cytochrome c, while facilitated the expression of creb at 24 h post ka-induced lesion in the hippocampus. |
2020-10-01 |
2023-08-13 |
rat |
| Jing Wang, Hong-Min Gu. Astragaloside IV ameliorates high glucose-induced HK-2 cell apoptosis and oxidative stress by regulating the Nrf2/ARE signaling pathway. Experimental and therapeutic medicine. vol 17. issue 6. 2020-10-01. PMID:31086575. |
cell viability, apoptosis and protein expression were detected by trypan blue staining, cell counting kit-8 assay, terminal deoxynucleotidyl transferase 2'-deoxyuridine-5'-triphosphate nick-end labelling, flow cytometry and western blot analyses. |
2020-10-01 |
2023-08-13 |
human |
| Yonglin Zhu, Luping Zhang, Rongzhan Fu, Limin Gao, Guoying Feng, Chao Du, Zhaojie Wang, Xinfeng Ya. The change tendency of endoplasmic reticulum stress associated proteins in rats with spinal cord injury. American journal of translational research. vol 11. issue 4. 2020-10-01. PMID:31105809. |
after sci, the expression of endoplasmic reticulum stress-induced apoptosis proteins were examined in the mice at specific time points using immunohistochemistry and western blot. |
2020-10-01 |
2023-08-13 |
mouse |
| Xin Zhang, Hong-Ming Zhan. Alantolactone induces gastric cancer BGC-823 cell apoptosis by regulating reactive oxygen species generation and the AKT signaling pathway. Oncology letters. vol 17. issue 6. 2020-10-01. PMID:31186685. |
cell cycle, cell apoptosis and the level of reactive oxygen species (ros) were assessed by flow cytometry, and the expression levels of proteins of interest were analyzed by western blot assay. |
2020-10-01 |
2023-08-13 |
human |
| Honghua Fei, Mingyan Shi, Lianhong Chen, Zhe Wang, Lihua Su. MicroRNA-18 promotes apoptosis of islet β-cells via targeting NAV1. Experimental and therapeutic medicine. vol 18. issue 1. 2020-10-01. PMID:31258677. |
apoptosis of min6 cells was detected by a terminal deoxynucleotidyl transferase-mediated deoxyuridinetriphosphate nick end labeling assay and western blot analysis of apoptotic proteins. |
2020-10-01 |
2023-08-13 |
Not clear |
| Kimia Sheikholeslami, Annan Ali Sher, Sandhini Lockman, Daniel Kroft, Meysam Ganjibakhsh, Kazem Nejati-Koshki, Shahla Shojaei, Saeid Ghavami, Mojgan Rastega. Simvastatin Induces Apoptosis in Medulloblastoma Brain Tumor Cells via Mevalonate Cascade Prenylation Substrates. Cancers. vol 11. issue 7. 2020-10-01. PMID:31319483. |
western blot analysis shows that simvastatin leads to changes in the expression of regulator proteins involved in apoptosis, such as bax, bcl-2, and bcl-xl. |
2020-10-01 |
2023-08-13 |
human |
| Xia Hua, Guangxing Li, Zhongtao Liu, Zhanfeng Ni. LINK-A lncRNA participates in the pathogenesis of glioma by interacting with survivin. Experimental and therapeutic medicine. vol 18. issue 3. 2020-10-01. PMID:31410112. |
link-a lncrna sirna, link-a lncrna-carrying expression vector and survivin-carrying expression vector were transfected into glioma cells, and the effects on link-a lncrna expression, survivin expression and cell apoptosis were explored by rt-qpcr, western blot analysis and annexin v/propidium iodide staining. |
2020-10-01 |
2023-08-13 |
Not clear |
| Guoxin Tong, Yongmei Wang, Chenke Xu, Yizhou Xu, Xianhua Ye, Liang Zhou, Gangjie Zhu, Zhanlin Zhou, Jinyu Huan. Long non-coding RNA FOXD3-AS1 aggravates ischemia/reperfusion injury of cardiomyocytes through promoting autophagy. American journal of translational research. vol 11. issue 9. 2020-10-01. PMID:31632535. |
moreover, cell apoptosis was measured by a flow cytometry assay and the expression levels of apoptosis associated proteins were evaluated by western blot. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xiangzhong Huang, Wen Xie, Xiaofan Yu, Caiyun Fan, Jin Wang, Yi Cao, Jianxiang L. Methyl-Cantharidimide Inhibits Growth of Human Hepatocellular Carcinoma Cells by Inducing Cell Cycle Arrest and Promoting Apoptosis. Frontiers in oncology. vol 9. 2020-10-01. PMID:31803617. |
furthermore, western blot was used to evaluate biomarkers associated with cell cycle and apoptosis. |
2020-10-01 |
2023-08-13 |
human |
| Tieyu Tang, Zuowei Duan, Jiang Xu, Jingyan Liang, Shuai Zhang, Haifeng Zhang, Xinjiang Zhang, Yingge Wan. Pterostilbene reduces endothelial cell injury in vascular arterial walls by regulating the Nrf2-mediated AMPK/STAT3 pathway in an atherosclerosis rat model. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31853271. |
the effects of pts on apoptosis and oxidative stress injury were measured using atherosclerotic lesion analysis, western blot analysis, hematoxylin and eosin straining, tunel assay and immunohistochemistry. |
2020-10-01 |
2023-08-13 |
rat |
| Peng Xiao, Xiaoming Zhang, Yanfei Li, Zhongyi Ma, Shuping Si, Xinxue Ga. miR-9 inhibition of neuronal apoptosis and expression levels of apoptosis genes Bcl-2 and Bax in depression model rats through Notch pathway. Experimental and therapeutic medicine. vol 19. issue 1. 2020-10-01. PMID:31853322. |
moreover, the neuronal apoptosis in the brain was determined through terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) assay, and the protein levels of notch1 and hes1 in brain tissues were measured via western blot analysis. |
2020-10-01 |
2023-08-13 |
rat |
| Dan-Yang Li, Jing-Dong Song, Zhao-Yuan Liang, Kiana Oskouei, Xiang-Qian Xiao, Wen-Zhe Hou, Jin-Tao Li, Yi-Shu Yang, Ming-Lian Wang, Manuel Murbac. Apoptotic Effect of 1800 MHz Electromagnetic Radiation on NIH/3T3 Cells. International journal of environmental research and public health. vol 17. issue 3. 2020-10-01. PMID:32013005. |
to investigate the effect of 1800 mhz electromagnetic radiation (emr) on apoptosis, we exposed nih/3t3 cells at 1800 mhz with a specific absorption rate (sar) of 2 w/kg intermittently for 12, 24, 36, and 48 h. after exposure, cell counting kit-8 (cck-8) and flow cytometry were used to detect cell viability and apoptosis; the expression of p53, a molecule with the key role in apoptosis, was measured by real-time qpcr, western blot, and immunofluorescence; and images of the structure of the mitochondria, directly reflecting apoptosis, were captured by electron microscopy. |
2020-10-01 |
2023-08-13 |
Not clear |
| Wenwen Si, Zhen Li, Zifeng Huang, Shanyu Ye, Xinrong Li, Yi Li, Weihong Kuang, Dongfeng Chen, Meiling Zh. RNA Binding Protein Motif 3 Inhibits Oxygen-Glucose Deprivation/Reoxygenation-Induced Apoptosis Through Promoting Stress Granules Formation in PC12 Cells and Rat Primary Cortical Neurons. Frontiers in cellular neuroscience. vol 14. 2020-10-01. PMID:32982696. |
the western blot results, flow cytometry analysis, and cell viability assessment showed that the rbm3 expression and ratio of cell viability significantly decreased, while the rate of apoptosis increased in pc12 cells during the reperfusion period after 6 h of ogd stimulation. |
2020-10-01 |
2023-08-13 |
rat |