| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pang-Hu Zhou, Lei Shi, Bo Qi. Protective effect of controlled release of cytokine response modifier A from chitosan microspheres on rat chondrocytes from interleukin-1β induced inflammation and apoptosis. Experimental and therapeutic medicine. vol 14. issue 4. 2020-10-01. PMID:28912867. |
in addition, cs-crma microspheres blocked il-1β-induced chondrocyte apoptosis by increasing b-cell lymphoma 2 (bcl-2) and decreasing bcl-2-associated x protein, caspase-3 and poly adenosine diphosphate-ribose polymerase expression at the mrna and protein levels, as indicated by reverse-transcription quantitative polymerase chain reaction and western blot analysis, respectively. |
2020-10-01 |
2023-08-13 |
rat |
| Wei-Lung Chen, Chia-Ling Hsieh, Jiann-Hwa Chen, Chih-Sheng Huang, Wei-Ting Chen, Yu-Cheng Kuo, Cheng-Yu Chen, Fei-Ting Hs. Amentoflavone enhances sorafenib-induced apoptosis through extrinsic and intrinsic pathways in sorafenib-resistant hepatocellular carcinoma SK-Hep1 cells Oncology letters. vol 14. issue 3. 2020-10-01. PMID:28927070. |
the effects of amentoflavone on sorafenib-induced cytotoxicity and apoptosis were then investigated using mtt, flow cytometry, dna gel electrophoresis and western blot analysis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Han Bao, Chun-Guang Guo, Peng-Cheng Qiu, Xin-Lei Zhang, Qi Dong, Yu-Kun Wan. Long non-coding RNA Igf2as controls hepatocellular carcinoma progression through the ERK/MAPK signaling pathway. Oncology letters. vol 14. issue 3. 2020-10-01. PMID:28928822. |
flow cytometry was used to determine the level of cell apoptosis following igf2as suppression and western blot analysis was used to identify altered protein expression levels. |
2020-10-01 |
2023-08-13 |
human |
| Yi Shi, Wei-Zhong Wu, An Huo, Wei Zhou, Xiao-Hong Ji. Isobavachalcone inhibits the proliferation and invasion of tongue squamous cell carcinoma cells. Oncology letters. vol 14. issue 3. 2020-10-01. PMID:28928824. |
the function of ibc on tca8113 cell apoptosis and apoptosis-associated signaling pathways was determined using an mtt assay, morphological staining, annexin v-propidium iodide (pi) staining and western blot analysis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xuan Li, Kai Wei, Rong Hu, Bo Zhang, Li Li, Li Wan, Chuanhan Zhang, Wenlong Ya. Upregulation of Cdh1 Attenuates Isoflurane-Induced Neuronal Apoptosis and Long-Term Cognitive Impairments in Developing Rats. Frontiers in cellular neuroscience. vol 11. 2020-10-01. PMID:29218001. |
in this study, postnatal day-7 (p7) rat pups and primary hippocampal neurons were exposed to 2% isoflurane for 6 h. terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) staining was used to detect neuronal apoptosis, and the expression of proteins involved in apoptosis (cleaved caspase-3, bax and bcl-2) was assessed by western blot. |
2020-10-01 |
2023-08-13 |
rat |
| Weilan Kong, Kai Kang, Yang Gao, Haitao Liu, Xianglin Meng, Songliu Yang, Kaijiang Yu, Mingyan Zha. Dexmedetomidine alleviates LPS-induced septic cardiomyopathy via the cholinergic anti-inflammatory pathway in mice. American journal of translational research. vol 9. issue 11. 2020-10-01. PMID:29218102. |
the pathological examinations were performed on he- stained myocardium tissues, apoptosis was determined using tunel assay, mrna expression of nf-κb p65, caspase-3, caspase-8, bcl-2, bax, p53 and α7nach was quantified using qrt-pcr, protein levels of il-6, il-1β, tnf-α and phosphorylated stat3 (p-stat3) were analyzed using western blot analysis. |
2020-10-01 |
2023-08-13 |
mouse |
| Kun Lu, Gang Rui, Fan Liu, Ling Yang, Xiaoling Deng, Songlin Shi, Qifu L. 14-3-3ε is a nuclear matrix protein, and its altered expression and localization are associated with curcumin-induced apoptosis of MG-63 cells. Oncology letters. vol 15. issue 1. 2020-10-01. PMID:29285195. |
in addition, western blot analysis validated that the expression level of 14-3-3ε was downregulated during curcumin-induced apoptosis of mg-63 cells compared with that in control cells. |
2020-10-01 |
2023-08-13 |
human |
| Xiao-Ling Feng, Hui-Zhi Fei, Ling H. Dexamethasone induced apoptosis of A549 cells via the TGF-β1/Smad2 pathway. Oncology letters. vol 15. issue 3. 2020-10-01. PMID:29435007. |
the apoptosis rate was measured by hoechst 33342 and annexin v/propidium iodide staining and the expression of transforming growth factor (tgf)-β1, smad family member 2 (smad2) and caspase-3 were assessed by western blot. |
2020-10-01 |
2023-08-13 |
Not clear |
| Xu Zhou, Daijiao Yi, Yanhong Wu, Xinghua Pei, Haiming Yu, Yanhong Chen, Yu Jiang, Wenpu L. Expression of diaphragmatic myostatin and correlation with apoptosis in rats with chronic obstructive pulmonary disease. Experimental and therapeutic medicine. vol 15. issue 3. 2020-10-01. PMID:29456636. |
diaphragmatic myostatin expression and apoptosis were measured by western blot and terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick end labeling, respectively. |
2020-10-01 |
2023-08-13 |
rat |
| Ziwei Wang, Feng J. Downregulation of microRNA-17-5p inhibits drug resistance of gastric cancer cells partially through targeting p21. Oncology letters. vol 15. issue 4. 2020-10-01. PMID:29541229. |
western blot analysis and flow cytometric assay revealed that the downregulation of mir-17-5p increases the sensitivity of sgc7901/ddp cells to ddp-induced apoptosis. |
2020-10-01 |
2023-08-13 |
Not clear |
| Qin Rui, Haibo Ni, Fan Gao, Baoqi Dang, Di Li, Rong Gao, Gang Che. LRRK2 Contributes to Secondary Brain Injury Through a p38/Drosha Signaling Pathway After Traumatic Brain Injury in Rats. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:29545743. |
real-time pcr, western blot, immunofluorescence, neuronal apoptosis, brain water content, and neurological score analyses were conducted. |
2020-10-01 |
2023-08-13 |
rat |
| Xinlei Wang, Guoyou Ding, Wei Lai, Shiwen Liu, Jun Shua. MicroRNA-383 upregulation protects against propofol-induced hippocampal neuron apoptosis and cognitive impairment. Experimental and therapeutic medicine. vol 15. issue 4. 2020-10-01. PMID:29545833. |
the learning memory ability, hippocampal neuron apoptosis and expression of apoptosis-associated factors were detected using reverse transcription-quantitiative polymerase chain reaction and western blot analysis. |
2020-10-01 |
2023-08-13 |
rat |
| Jing Zhu, Ying Xin, Xiaoliang Liu, Ying Wang, Ying Li. Nimotuzumab enhances the sensitivity of non-small cell lung cancer cells to tumor necrosis factor-α by inhibiting the nuclear factor-кB signaling pathway. Experimental and therapeutic medicine. vol 15. issue 4. 2020-10-01. PMID:29545853. |
the effect of nimotuzumab (ni) on nsclc cell sensitivity to tnf-α, as well as the role of nf-κb in mediating resistance to tnf-α-induced apoptosis, was explored by western blot analysis, cell viability assay, apoptosis assay and an nf-κb dna binding assay. |
2020-10-01 |
2023-08-13 |
Not clear |
| Shuo Tu, Xia-Li Zhang, Hui-Fang Wan, Yan-Qin Xia, Zhuo-Qi Liu, Xiao-Hong Yang, Fu-Sheng Wa. Effect of taurine on cell proliferation and apoptosis human lung cancer A549 cells. Oncology letters. vol 15. issue 4. 2020-10-01. PMID:29552188. |
western blot analysis was performed to examine the levels of p53 upregulated modulator of apoptosis (puma), bcl2, apoptosis regulator (bcl-2) and bcl2-associated x, apoptosis regulator (bax) in a549 cells. |
2020-10-01 |
2023-08-13 |
mouse |
| Yu Fu, Yingze Wan. SRSF7 knockdown promotes apoptosis of colon and lung cancer cells. Oncology letters. vol 15. issue 4. 2020-10-01. PMID:29556298. |
mts assays, western blot analysis, flow cytometry and spectrofluorometer analyses were performed to assess the effects of srsf7 knockdown on the proliferation and apoptosis of cells. |
2020-10-01 |
2023-08-13 |
Not clear |
| Hui Yang, Hongcai Wang, Yongwei Shu, Xuling L. miR-103 Promotes Neurite Outgrowth and Suppresses Cells Apoptosis by Targeting Prostaglandin-Endoperoxide Synthase 2 in Cellular Models of Alzheimer's Disease. Frontiers in cellular neuroscience. vol 12. 2020-10-01. PMID:29674956. |
total neurite outgrowth was detected by microscope, cells apoptosis was determined by hoechst/pi assay, and apoptotic markers caspase 3 and p38 expressions were determined by western blot assay. |
2020-10-01 |
2023-08-13 |
mouse |
| Shuai Mao, Peipei Chen, Ting Li, Liheng Guo, Minzhou Zhan. Tongguan Capsule Mitigates Post-myocardial Infarction Remodeling by Promoting Autophagy and Inhibiting Apoptosis: Role of Sirt1. Frontiers in physiology. vol 9. 2020-10-01. PMID:29872406. |
histological and western blot analyses revealed decreased cellular inflammation and apoptosis in cardiomyocytes of the tgc group. |
2020-10-01 |
2023-08-13 |
mouse |
| Yali Gao, Zishen Zhao, Xiaoyin Meng, Hongguag Chen, Guojun F. Migration and invasion in B16-F10 mouse melanoma cells are regulated by Nrf2 inhibition during treatment with ionizing radiation. Oncology letters. vol 16. issue 2. 2020-10-01. PMID:30008889. |
small interfering (si)rnas targeting nrf2 were transfected into b16-f10 cells, and cell proliferation, invasion and apoptosis were detected by transwell, mtt or western blot assays. |
2020-10-01 |
2023-08-13 |
mouse |
| Thangavel Muthukumarasamyvel, Ganapathy Rajendran, Devendrapandi Santhana Panneer, Jayapalan Kasthuri, Krishnan Kathiravan, Nagappan Rajendira. Role of Surface Hydrophobicity of Dicationic Amphiphile-Stabilized Gold Nanoparticles on A549 Lung Cancer Cells. ACS omega. vol 2. issue 7. 2020-10-01. PMID:30023697. |
the anticancer activity of these dicationic amphiphile-stabilized aunps on a549 lung cancer cells was demonstrated by in vitro cell viability assay, intracellular reactive oxygen species estimation by dcfh-da, apoptosis analysis using ao-etbr fluorescence staining, dna fragmentation analysis by agarose gel electrophoresis, and western blot analysis of caspase-3 expression. |
2020-10-01 |
2023-08-13 |
human |
| Jiayu Chen, Yanrong Hao, Jiaxin Chen, Li Huang, Wen Ao, Jiao Yang, Lei Li, Junping Heng, Zhaohon Chen, Wuqing Liang, Xin Hao, Weiwei Ga. Colony stimulating factor-1 receptor promotes proliferation, migration and invasion in the human nasopharyngeal carcinoma 6-10B cell line via the phosphoinositide 3-kinase/Akt pathway. Oncology letters. vol 16. issue 1. 2020-10-01. PMID:30061942. |
additionally, western blot analysis was used to detect the protein expression of the proliferation and apoptosis signaling factors cyclin d1, b-cell lymphoma 2, bcl-2-associated x protein, and phosphorylated and total extracellular protein kinase b (akt/pkb) in 6-10b cells. |
2020-10-01 |
2023-08-13 |
human |