| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhiliang Li, Songfeng Chen, Sheng Chen, Donghua Huang, Kaige Ma, Zengwu Sha. Moderate activation of Wnt/β-catenin signaling promotes the survival of rat nucleus pulposus cells via regulating apoptosis, autophagy, and senescence. Journal of cellular biochemistry. vol 120. issue 8. 2020-09-16. PMID:31016779. |
after 0, 24, and 48 hours of compression, apoptosis, autophagy, and senescence were evaluated by western blot analysis and real-time polymerase chain reaction and were visually observed by hoechst33258, monodansylcadaverine, and sa-β-gal stainings, respectively. |
2020-09-16 |
2023-08-13 |
rat |
| Preedajit Wongkrasant, Pawin Pongkorpsakol, Sasirin Chitwattananont, Wilasinee Satianrapapong, Nuttha Tuangkijkul, Chatchai Muanprasa. Fructo-oligosaccharides alleviate inflammation-associated apoptosis of GLP-1 secreting L cells via inhibition of iNOS and cleaved caspase-3 expression. Journal of pharmacological sciences. vol 143. issue 2. 2020-09-15. PMID:32229084. |
herein, using cell death assays, immunofluorescence staining, real time pcr and western blot analyses, we found that tnf-α induced l cell apoptosis via nuclear factor kappa b (nf-κb)- inducible nitric oxide synthase (inos)-cleaved caspase-3-dependent pathways. |
2020-09-15 |
2023-08-13 |
Not clear |
| Hua-Shu Yuan, Dai-Qun Xiong, Fang Huang, Jian Cui, Hui Lu. MicroRNA-421 inhibition alleviates bronchopulmonary dysplasia in a mouse model via targeting Fgf10. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-14. PMID:31144392. |
inflammatory response and cell apoptosis were observed in the mice, with inflammatory cytokines and apoptosis-related factors detected by applying reverse transcription quantitative polymerase chain reaction, western blot analysis, and enzyme-linked immunosorbent assay. |
2020-09-14 |
2023-08-13 |
mouse |
| Youbo Zuo, Xingping Hu, Qiuyan Yang, Lei Zhao, Xueli Chen, Jiangtao Lin, Tiande Yan. Preoperative vitamin-rich carbohydrate loading alleviates postoperative cognitive dysfunction in aged rats. Behavioural brain research. vol 373. 2020-09-14. PMID:31340174. |
the levels of endoplasmic reticulum (er) stress markers and apoptosis related proteins in the hippocampus were examined by western blot analysis. |
2020-09-14 |
2023-08-13 |
rat |
| Ying Xiong, Hui Huang, Shaoping Chen, Haitao Dai, Luying Zhan. ERK5‑regulated RERG expression promotes cancer progression in prostatic carcinoma. Oncology reports. vol 41. issue 2. 2020-09-11. PMID:30431143. |
furthermore, an apoptotic assay and western blot analysis demonstrated that the downregulation of rerg expression inhibits apoptosis by regulating the protein expression levels of b cell lymphoma‑2 and c‑myc. |
2020-09-11 |
2023-08-13 |
Not clear |
| Jian Jin, Ajuan Chen, Weizheng Qiu, Yilin Chen, Qingchu Li, Xinying Zhou, Dadi Ji. Dysregulated circRNA_100876 suppresses proliferation of osteosarcoma cancer cells by targeting microRNA-136. Journal of cellular biochemistry. vol 120. issue 9. 2020-09-11. PMID:31069828. |
flow cytometry and western blot analysis results showed that the downregulation of circrna_100876 inhibited osteosarcoma cells proliferation via promoting apoptosis and arresting more cells in the g2/m stage, as suggested by the expression of apoptosis and cell cycle pathway-related proteins, which changed consistently. |
2020-09-11 |
2023-08-13 |
Not clear |
| Debin Xu, Jichun Yu, Shimin Zhuang, Shuyong Zhang, Zhengdong Hong, Chunlei Yua. Overexpression of long non-coding RNA LINC00982 suppresses cell proliferation and tumor growth of papillary thyroid carcinoma through PI3K-ATK signaling pathway. Bioscience reports. vol 39. issue 7. 2020-09-11. PMID:31262968. |
furthermore, western blot assay was used to measure the alteration expression levels of apoptosis relative proteins and the relative protein involved phosphatidylinositol 3-kinase (pi3k)/akt signaling pathway. |
2020-09-11 |
2023-08-13 |
human |
| Lianqi Shao, Qianru He, Yunhui Liu, Xiaobai Liu, Jian Zheng, Jun Ma, Libo Liu, Han Li, Zhen Li, Yixue Xu. UPF1 regulates the malignant biological behaviors of glioblastoma cells via enhancing the stability of Linc-00313. Cell death & disease. vol 10. issue 9. 2020-09-11. PMID:31427569. |
here, we used qrt-pcr and western blot to measure the expression, cell transfection to disrupt the expression of genes, cell viability analysis, quantization of apoptosis, cell migration, and invasion assays, reporter vectors construction and luciferase assays to investigate the malignant biological behaviors of cells, human lncrna microarrays, rna-immunoprecipitation, dual-luciferase gene reporter assay, half-life assay and chromatin immunoprecipitation to verify the binding sites, tumor xenograft implantation for in vivo experiment, spss 18.0 statistical software for data statistics. |
2020-09-11 |
2023-08-13 |
human |
| Sema Misir, Yüksel Aliyazicioglu, Selim Demir, Ibrahim Turan, Ceylan Hepoku. Effect of Turkish Propolis on miRNA Expression, Cell Cycle, and Apoptosis in Human Breast Cancer (MCF-7) Cells. Nutrition and cancer. vol 72. issue 1. 2020-09-10. PMID:31112051. |
mechanisms involved in the cytotoxic action of turkish propolis in mcf-7 cells were investigated with regard to apoptosis and cell cycle using flow cytometry and western blot. |
2020-09-10 |
2023-08-13 |
human |
| Yanbei Sun, Tingxiu Jiang, Yongqing Jia, Jingyun Zou, Xiaoxiao Wang, Weiying G. LncRNA MALAT1/miR-181a-5p affects the proliferation and adhesion of myeloma cells via regulation of Hippo-YAP signaling pathway. Cell cycle (Georgetown, Tex.). vol 18. issue 19. 2020-09-09. PMID:31397203. |
western blot analysis was used to analyze the expression of proliferation and apoptosis related proteins and hippo-yes-associated protein (yap) signaling pathway related proteins. |
2020-09-09 |
2023-08-13 |
Not clear |
| Alireza Shirpoor, Reza Gaderi, Roya Nader. Ethanol exposure in prenatal and early postnatal induced cardiac injury in rats: involvement of oxidative stress, Hsp70, ERK 1/2, JNK, and apoptosis in a 3-month follow-up study. Cell stress & chaperones. vol 24. issue 5. 2020-09-09. PMID:31410726. |
histopathological examinations and western blot were performed to evaluate histological features, apoptosis, and molecular alterations in the myocardial tissue of male pups on the postnatal day 21 (pn-21) and postnatal day 90 (pn-90). |
2020-09-09 |
2023-08-13 |
rat |
| Zhixin Qiu, Bingwei Ye, Shuang Zhao, Xin Li, Lei Li, Ximing Mo, Weimin L. Non-canonical Raf-1/p70S6K signalling in non-small-cell lung cancer. Journal of cellular and molecular medicine. vol 23. issue 11. 2020-09-09. PMID:31541523. |
tumours were measured and weighed, and raf-1 and p70s6k expression, cell proliferation and apoptosis were examined in tumour tissues by western blot, ki-67 staining and tunel staining, respectively. |
2020-09-09 |
2023-08-13 |
Not clear |
| A Qu, Q Yan. LncRNA SNHG1 promotes cell progression and metastasis via sponging miR-377-3p in hepatocellular carcinoma. Neoplasma. vol 67. issue 3. 2020-09-09. PMID:32122143. |
cell apoptosis was evaluated by detecting the apoptotic rate and the protein level of c-caspase 3 using flow cytometry and western blot assays. |
2020-09-09 |
2023-08-13 |
Not clear |
| Laifang Wang, Na Wang, Qing Zhao, Bingyi Zhang, Yanjie Din. Pectolinarin inhibits proliferation, induces apoptosis, and suppresses inflammation in rheumatoid arthritis fibroblast-like synoviocytes by inactivating the phosphatidylinositol 3 kinase/protein kinase B pathway. Journal of cellular biochemistry. vol 120. issue 9. 2020-09-08. PMID:31020684. |
apoptosis was determined by flow cytometry analysis and western blot analysis of bax and bcl-2 levels. |
2020-09-08 |
2023-08-13 |
Not clear |
| Tesi Liu, Guang Zhu, Wendi Yan, You Lv, Xue Wang, Guang Jin, Minghua Cui, Zhenhua Lin, Xiangshan Re. Cordycepin Inhibits Cancer Cell Proliferation and Angiogenesis through a DEK Interaction via ERK Signaling in Cholangiocarcinoma. The Journal of pharmacology and experimental therapeutics. vol 373. issue 2. 2020-09-08. PMID:32102917. |
dek silencing inhibited cca cell viability and angiogenesis but not apoptosis induction determined by western blot and flow cytometry. |
2020-09-08 |
2023-08-13 |
Not clear |
| Xi'an Zhang, Zhanhui Liu, Qing Shu, Shanqi Yuan, Zhiguo Xing, Jinning Son. LncRNA SNHG6 functions as a ceRNA to regulate neuronal cell apoptosis by modulating miR-181c-5p/BIM signalling in ischaemic stroke. Journal of cellular and molecular medicine. vol 23. issue 9. 2020-09-04. PMID:31334597. |
ttc staining, quantitative real-time pcr, cell apoptosis assay, caspase-3 activity assay, western blot, rna immunoprecipitation and luciferase reporter assay were performed to evaluate the function and possible mechanisms of snhg6 in the pathogenesis of ischaemic stroke. |
2020-09-04 |
2023-08-13 |
mouse |
| Xue Zhang, Wenwen Pang, Hong Liu, Juan Wan. Lidocine potentiates the cytotoxicity of 5-fluorouracil to choriocarcinoma cells by downregulating ABC transport proteins expression. Journal of cellular biochemistry. vol 120. issue 10. 2020-09-02. PMID:31081972. |
viabilities and apoptosis of choriocarcinoma jeg-3 and jar cells after lidocaine and/or 5-fu treatment were detected using cell counting kit-8 assay, annexin v-fitc/pi (fluorescein isothiocyanate/propidium iodide) staining and western blot analysis, respectively. |
2020-09-02 |
2023-08-13 |
Not clear |
| Li Wenzhao, Ni Jiangdong, Song Deye, Ding Muliang, Wang Junjie, Huang Xianzhe, Yan Mingming, Huang Ju. Dual regulatory roles of HMGB1 in inflammatory reaction of chondrocyte cells and mice. Cell cycle (Georgetown, Tex.). vol 18. issue 18. 2020-09-01. PMID:31313630. |
in the current study, we used quantitative real-time pcr(q-pcr) to detect them rna levels of collagen type ii alpha 1(col2a1), aggrecan, mmp3(matrix metallopeptidase 3), mmp13, adamts4 and adamts5; enzyme-linked immunosorbent assay(elisa) was used to detect the content of il-1β and calpain protein; cell apoptosis was evaluated by terminal deoxynucleotidyl transferase-mediated dutp-biotin nick end labeling(tunel) assay and flow cytometryanalysis; western blot and immunofluorescence assays were applied to assess the expression of hmgb1; lastly autophagic activity was mainly verified by monodansylcadaverine (mdc) staining. |
2020-09-01 |
2023-08-13 |
mouse |
| Daniela Carneiro de Lima, Silvana Vianna Rodrigues, Gilson Teles Boaventura, Hee-Yeon Cho, Thomas C Chen, Axel H Schönthal, Clovis Orlando Da Fonsec. Simultaneous measurement of perillyl alcohol and its metabolite perillic acid in plasma and lung after inhalational administration in Wistar rats. Drug testing and analysis. vol 12. issue 2. 2020-09-01. PMID:31800149. |
toxicity was established by a standard mtt assay, and apoptosis markers were analyzed by western blot. |
2020-09-01 |
2023-08-13 |
rat |
| Hui Wang, Yuan Lu, Yan Yan, Shanshan Tian, Dongjie Zheng, Dongjing Leng, Cao Wang, Jingfeng Jiao, Zhiguo Wang, Yunlong Ba. Promising Treatment for Type 2 Diabetes: Fecal Microbiota Transplantation Reverses Insulin Resistance and Impaired Islets. Frontiers in cellular and infection microbiology. vol 9. 2020-09-01. PMID:32010641. |
furthermore, flow cytometry and western blot results revealed that fmt inhibited the β-cell apoptosis. |
2020-09-01 |
2023-08-13 |
mouse |