| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pankaj K Singh, Amit A Deorukhkar, Bhanu P Venkatesulu, Xiaolin Li, Ramesh Tailor, John S Bomalaski, Sunil Krishna. Exploiting Arginine Auxotrophy with Pegylated Arginine Deiminase (ADI-PEG20) to Sensitize Pancreatic Cancer to Radiotherapy via Metabolic Dysregulation. Molecular cancer therapeutics. vol 18. issue 12. 2020-07-07. PMID:31395686. |
reverse phase protein array studies confirmed increased expression of proteins related to endoplasmic reticulum (er) stress and apoptosis, which were confirmed by western blot analysis. |
2020-07-07 |
2023-08-13 |
human |
| Yu Shi, Yuqi Yang, Qinyu Guo, Qiuzhi Gao, Ying Ding, Hua Wang, Wenrong Xu, Bin Yu, Mei Wang, Yuanyuan Zhao, Wei Zh. Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Promote Fibroblast-to-Myofibroblast Differentiation in Inflammatory Environments and Benefit Cardioprotective Effects. Stem cells and development. vol 28. issue 12. 2020-06-29. PMID:30896296. |
cardiomyocyte apoptosis was determined using tunel assay and western blot. |
2020-06-29 |
2023-08-13 |
human |
| Di Wu, Li Jin, Hongshuang X. The Effects of the CXCR4 Antagonist, AMD3465, on Human Retinal Vascular Endothelial Cells (hRVECs) in a High Glucose Model of Diabetic Retinopathy. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-06-26. PMID:31860633. |
cell apoptosis and angiogenesis were assessed by flow cytometry and western blot. |
2020-06-26 |
2023-08-13 |
human |
| Zixin Chen, Xuan Su, Yan Shen, Yue Jin, Tong Luo, Il-Man Kim, Neal L Weintraub, Yaoliang Tan. MiR322 mediates cardioprotection against ischemia/reperfusion injury via FBXW7/notch pathway. Journal of molecular and cellular cardiology. vol 133. 2020-06-25. PMID:31150734. |
intramyocardial injection of mimic-mir322 significantly diminished cardiac apoptosis (as determined by expression levels of active caspase 3 by western blot analysis and immunostaining for tunel) and reduced infarct size by about 40%, in association with reduced fbxw7 and increased active notch 1 levels in the ischemic hearts. |
2020-06-25 |
2023-08-13 |
mouse |
| Jun Li, Sha-Sha Zuo, Xiao-Xuan Qiu, Xi Xu, Ying-Ying Luo, Hong-Wei Gao, Yu-Lin Feng, Li-Jun DU, Qin Gon. [Expression characteristics of inflammatory and apoptosis factors and regulatory effect of anemoside B4 in mice with acute kidney injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 45. issue 1. 2020-06-25. PMID:32237425. |
after the serum was separated, serum urea nitrogen(bun), creatinine(cre), total protein(tp), and albumin(alb) were tested by using an automatic biochemical analyzer; the changes of kidney pathological morphology were observed by pas staining; the protein expression levels of inflammatory factors including nucleotide binding oligomerization domain-like receptor(nlrp3), cysteinyl aspartate specific proteinase 1(caspase-1), interleukin-18(il-18), interleukin-1β(il-1β), tumor necrosis factor(tnf-α), and interleukin-6(il-6) and apoptosis factors including p53, caspase-3, cleaved-caspase-3, bcl-2 associated x protein(bax), and b-cell lymphoma-2(bcl-2) were analyzed by western blot. |
2020-06-25 |
2023-08-13 |
mouse |
| Qian Ding, Qing Wang, Yi Ren, Hong Qian Zhu, ZhuYun Huan. MicroRNA-126 attenuates cell apoptosis by targeting TRAF7 in acute myeloid leukemia cells. Biochemistry and cell biology = Biochimie et biologie cellulaire. vol 96. issue 6. 2020-06-22. PMID:29940130. |
furthermore, dual-luciferase assay and western blot were used to determine the target of mirna-126 in aml and the potential mechanism by which cell apoptosis is suppressed by mirna-126. |
2020-06-22 |
2023-08-13 |
Not clear |
| Nastaran Vahabi Barzi, Zohre Eftekhari, Delaram Doroud, Akram Eid. DNA methylation changes of apoptotic genes in organogenesis stage of mice embryos by maternal chlorpyrifos induction. Environmental toxicology. vol 35. issue 7. 2020-06-22. PMID:32149475. |
the apoptosis pathway genes (caspase3, caspase9) and protein expressions (pro-caspase3, caspase3) of the embryos were evaluated with qrt-pcr and western blot, respectively. |
2020-06-22 |
2023-08-13 |
mouse |
| Yuan Ji, Jian Shen, Min Li, Xiaoxiao Zhu, Yanyan Wang, Jiazheng Ding, Shunyao Jiang, Linqi Chen, Wenxiang We. RMP/URI inhibits both intrinsic and extrinsic apoptosis through different signaling pathways. International journal of biological sciences. vol 15. issue 12. 2020-06-16. PMID:31754340. |
western blot showed that in intrinsic apoptosis induced by cisplatin, the overexpression of rmp promoted the bcl-xl expression both |
2020-06-16 |
2023-08-13 |
Not clear |
| Yujin Lee, Young Hye Kwo. Regulation of apoptosis and autophagy by luteolin in human hepatocellular cancer Hep3B cells. Biochemical and biophysical research communications. vol 517. issue 4. 2020-06-15. PMID:31383362. |
western blot was applied to compare the difference of autophagy, apoptosis, and proliferation event between cell lines. |
2020-06-15 |
2023-08-13 |
human |
| Annett Kühnel, Daniela Schilling, Stephanie E Combs, Bernhard Haller, Melissa Schwab, Gabriele Multhof. Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922. Cells. vol 8. issue 10. 2020-06-15. PMID:31569342. |
protein expression (i.e., hsp27/hsp70, hsf-1, phsf-1, akt, ß-actin) and transcriptional activity was assessed by western blot analysis and luciferase assays and radiosensitivity was measured by proliferation, apoptosis (annexin v, active caspase 3), clonogenic cell survival, alkaline comet, γh2ax, 53bp1, and rad51 foci assays. |
2020-06-15 |
2023-08-13 |
Not clear |
| Li Ji, Xue L. Long noncoding RNA MEG3 is a tumor suppressor in choriocarcinoma by upregulation of microRNA-211. Journal of cellular physiology. vol 234. issue 12. 2020-06-11. PMID:31124134. |
lncrna meg3 was overexpressed, and the effects of lncrna meg3 on cell viability, proliferation, apoptosis, migration, and invasion were assessed by the cell counting kit-8 assay, western blot analysis, flow cytometry (plus western blot analysis), and transwell assay (plus western blot analysis), respectively. |
2020-06-11 |
2023-08-13 |
human |
| Xin Zhu, Xiaolan L. MiR-423-5p inhibition alleviates cardiomyocyte apoptosis and mitochondrial dysfunction caused by hypoxia/reoxygenation through activation of the wnt/β-catenin signaling pathway via targeting MYBL2. Journal of cellular physiology. vol 234. issue 12. 2020-06-09. PMID:31074036. |
cell apoptosis rate, caspase 3/7 activities, bax and cleaved-caspase 3 (c-caspase 3) protein levels were assayed by flow cytometry, caspase-glo 3/7 assay kit, western blot analysis, respectively. |
2020-06-09 |
2023-08-13 |
Not clear |
| Citong Zhang, Wei Wei, Minghan Chi, Yao Wan, Xue Li, Manlin Qi, Yanmin Zho. FOXO1 Mediates Advanced Glycation End Products Induced Mouse Osteocyte-Like MLO-Y4 Cell Apoptosis and Dysfunctions. Journal of diabetes research. vol 2019. 2020-06-09. PMID:31886284. |
qpcr and western blot results have shown that age upregulates proapoptotic gene p53 and its downstream target gene bax, which leads to enhanced activation of caspase-3, thus inducing apoptosis in mlo-y4 cells. |
2020-06-09 |
2023-08-13 |
mouse |
| Hui-Zhi Yang, Jiaojiao Zhang, Jie Zeng, Shengbo Liu, Fei Zhou, Fang Zhang, Francesca Giampieri, Danila Cianciosi, Tamara Y Forbes-Hernandez, Johura Ansary, Emilio Gil, RongYi Chen, Maurizio Battin. Resveratrol inhibits the proliferation of melanoma cells by modulating cell cycle. International journal of food sciences and nutrition. vol 71. issue 1. 2020-06-08. PMID:31154861. |
the aim of this study was to evaluate the inhibitory effects of resveratrol (rsv) in a375 and a431 melanoma cells, by assessing cell viability (cck-8 assay), apoptosis through flow cytometer and cell morphology, cell cycle assay by flow cytometer and western blot (cyclin d1, rac1 and pcdh9). |
2020-06-08 |
2023-08-13 |
Not clear |
| YanYan Yi, ShuangXiu Wan, YaXin Hou, Jia Cheng, JianHua Guo, Shaoyu Wang, Ajab Khan, Na Sun, Hongquan L. Chlorogenic acid rescues zearalenone induced injury to mouse ovarian granulosa cells. Ecotoxicology and environmental safety. vol 194. 2020-06-05. PMID:32143102. |
western blot analysis suggested chlorogenic acid could rescue the up-regulated apoptosis of gcs induced by zea via attenuating the protein expression of cleaved caspase-3, the ratio of bax/bcl-2 and cleaved-parp. |
2020-06-05 |
2023-08-13 |
mouse |
| Linping Li, Yuanxia Shao, Hongjian Zheng, Heng Ni. Kaempferol Regulates miR-15b/Bcl-2/TLR4 to Alleviate OGD-Induced Injury in H9c2 Cells. International heart journal. vol 61. issue 3. 2020-06-05. PMID:32418959. |
afterward, cell transfection, dual-luciferase activity assay, and western blot were used to explore the potential mechanisms.ogd treatment suppressed cell viability, whereas it enhanced cell apoptosis. |
2020-06-05 |
2023-08-13 |
human |
| M Chen, L-L Zhu, J-L Su, G-L Li, J Wang, Y-N Zhan. Prucalopride inhibits lung cancer cell proliferation, invasion, and migration through blocking of the PI3K/AKT/mTor signaling pathway. Human & experimental toxicology. vol 39. issue 2. 2020-06-02. PMID:31640407. |
cell apoptosis was detected by flow cytometry and western blot analyses. |
2020-06-02 |
2023-08-13 |
human |
| Meihan Liu, Jingzhe Zhang, Hang Dong, Wenjun Wan. Nimotuzuma restrains proliferation and induces apoptosis in human osteosarcoma cells by regulation of EGFR/PI3K/AKT signal pathway. Journal of cellular physiology. vol 234. issue 11. 2020-06-01. PMID:31001861. |
the proteins of cell apoptosis, cell cycle, and egfr/pi3k/akt were appraised via western blot. |
2020-06-01 |
2023-08-13 |
human |
| Qi Wang, Lei Zhang, Yong Cui, Chi Zhang, Huairui Chen, Juan Gu, Jun Qian, Chun Lu. Increased RLIP76 expression in IDH1 wild‑type glioblastoma multiforme is associated with worse prognosis. Oncology reports. vol 43. issue 1. 2020-06-01. PMID:31746408. |
the effects of rlip76 expression and idh1 mutational status on cell proliferation, cell apoptosis, and cell signaling were examined by cell counting kit‑8, flow cytometry and western blot assays, respectively. |
2020-06-01 |
2023-08-13 |
Not clear |
| Hamidreza Moazzeni, Mehraban Mirrahimi, Abolfazl Moghadam, Amir Banaei-Esfahani, Shahin Yazdani, Elahe Elah. Identification of genes involved in glaucoma pathogenesis using combined network analysis and empirical studies. Human molecular genetics. vol 28. issue 21. 2020-05-26. PMID:31518395. |
selected features of the network were confirmed by empirical studies such as dual luciferase assays, real-time pcr and western blot experiments and apoptosis assays. |
2020-05-26 |
2023-08-13 |
Not clear |