| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nana Nie, Cui Bai, Shanai Song, Yanyan Zhang, Benzhen Wang, Zipu L. Bifidobacterium plays a protective role in TNF-α-induced inflammatory response in Caco-2 cell through NF-κB and p38MAPK pathways. Molecular and cellular biochemistry. vol 464. issue 1-2. 2020-03-18. PMID:31741130. |
cell apoptosis was measured by flow cytometry and the expression of apoptosis related proteins was also detected through western blot. |
2020-03-18 |
2023-08-13 |
Not clear |
| Yingying Han, Chunyang Kang, Mingyang Kang, Wei Quan, Heming Gao, Zhuan Zhon. Long non-coding RNA Mirt2 prevents TNF-α-triggered inflammation via the repression of microRNA-101. International immunopharmacology. vol 76. 2020-03-17. PMID:31513985. |
proteins associated with apoptosis, interleukin (il) and signaling regulators were evaluated by western blot. |
2020-03-17 |
2023-08-13 |
Not clear |
| Marta Henklewska, Aleksandra Pawlak, Justyna Kutkowska, Hanna Pruchnik, Andrzej Rapak, Bozena Obminska-Mrukowic. In vitro effects of the activity of novel platinum (II) complex in canine and human cell lines. Veterinary and comparative oncology. vol 17. issue 4. 2020-03-05. PMID:31111625. |
expression of main proteins involved in apoptosis was measured after exposure for 24 hours to 3 or 5 μm pt-tcep in western blot. |
2020-03-05 |
2023-08-13 |
human |
| Zhaofeng Han, Yimeng Zhu, Zhengjun Cui, Pengfei Guo, Aizhou Wei, Qingnan Men. MicroRNA Let-7f-1-3p attenuates smoke-induced apoptosis in bronchial and alveolar epithelial cells in vitro by targeting FOXO1. European journal of pharmacology. vol 862. 2020-03-05. PMID:31301310. |
these cells were treated with let-7f-1-3p agomir or antagomir for 24 h before smoke exposure or sham operation, after which the cells were rinsed and cultured for 24 h before cell viability, apoptosis, cytolysis, caspase-9/8/3 activity assays, quantitative real-time polymerase chain reaction and western blot. |
2020-03-05 |
2023-08-13 |
human |
| Chengguo Su, Yuzhou Chen, Yunfei Chen, Yin Zhou, Lianbo Li, Qunwen Lu, Huahui Liu, Xiaochao Luo, Jun Zh. Effect of electroacupuncture at the ST36 and GB39 acupoints on apoptosis by regulating the p53 signaling pathway in adjuvant arthritis rats. Molecular medicine reports. vol 20. issue 5. 2020-03-03. PMID:31545441. |
in addition, the expression levels of the apoptosis‑associated proteins, bax, phorbol‑12‑myristate‑13‑acetate‑induced protein 1 (noxa) and p53 upregulated modulator of apoptosis (puma), were determined by western blot analysis. |
2020-03-03 |
2023-08-13 |
mouse |
| Luca Mazzoni, Francesca Giampieri, Jose Miguel Alvarez Suarez, Massimiliano Gasparrini, Bruno Mezzetti, Tamara Yuliett Forbes Hernandez, Maurizio Antonio Battin. Isolation of strawberry anthocyanin-rich fractions and their mechanisms of action against murine breast cancer cell lines. Food & function. vol 10. issue 11. 2020-02-27. PMID:31621765. |
western blot assays were performed to analyze the expression of several proteins related to apoptosis, autophagy, metastasis, the oxidative status, mitochondrial functionality, and the ampk pathway. |
2020-02-27 |
2023-08-13 |
Not clear |
| Bin Sun, Changxian Dong, Hongzhao Lei, Yubin Gong, Miaomiao Li, Yuanfang Zhang, Hongyu Zhang, Longlong Su. Propranolol inhibits proliferation and induces apoptosis of hemangioma-derived endothelial cells via Akt pathway by down-regulating Ang-2 expression. Chemico-biological interactions. vol 316. 2020-02-27. PMID:31838054. |
cell apoptosis was measured by flow cytometry analysis and western blot of bax and bcl-2 levels. |
2020-02-27 |
2023-08-13 |
human |
| Qi Zhu, Wei Zhang, Deguang Mu, Hongbin Zhou, Shengchang Wu, Hai Zo. Effects of genistein on lipopolysaccharide-induced injury of mouse alveolar epithelial cells and its mechanism. Bioscience, biotechnology, and biochemistry. vol 84. issue 3. 2020-02-26. PMID:31791192. |
flow cytometry and western blot assay were performed to detect cells apoptosis and protein levels. |
2020-02-26 |
2023-08-13 |
mouse |
| Weijun Gong, Shuyan Qie, Peiling Huang, Jianing X. Deletion of long noncoding RNA EFNA3 aggravates hypoxia-induced injury in PC-12 cells by upregulation of miR-101a. Journal of cellular biochemistry. vol 120. issue 1. 2020-02-25. PMID:30125989. |
cell viability, migration, invasion, and apoptosis were, respectively, determined by trypan blue staining, transwell assay, annexin v-fluorescein isothiocyanate (fitc)/propidium iodide (pi) double-staining, and western blot analysis. |
2020-02-25 |
2023-08-13 |
rat |
| Mohammed A Ramadan, Alaa E Shawkey, Mohamed A Rabeh, Ashraf O Abdellati. Expression of P53, BAX, and BCL-2 in human malignant melanoma and squamous cell carcinoma cells after tea tree oil treatment in vitro. Cytotechnology. vol 71. issue 1. 2020-02-25. PMID:30599074. |
the present study aimed to investigate the cytotoxic effects of tto against two representative types of human skin cancer, namely malignant melanoma (a-375) and squamous cell carcinoma (hep-2).to outline the basic molecular mechanism involved in apoptosis induction in a-375 and hep-2 cell lines, annexin v/pi staining for apoptosis detection, cell cycle analysis were monitored using flow cytometry and mrna expression levels of the apoptosis-regulatory genes p53, bax, and bcl-2 were determined by real-time pcr and western blot after treatment with tto. |
2020-02-25 |
2023-08-13 |
human |
| Lakshminarasimhan Harini, Sweta Srivastava, George Peter Gnanakumar, Bose Karthikeyan, Cecil Ross, Vaithilingam Krishnakumar, Velu Rajesh Kannan, Krishnan Sundar, Thandavarayan Kathiresa. An ingenious non-spherical mesoporous silica nanoparticle cargo with curcumin induces mitochondria-mediated apoptosis in breast cancer (MCF-7) cells. Oncotarget. vol 10. issue 11. 2020-02-25. PMID:30838091. |
western blot analysis suggest, curcumin induce apoptosis through the activation of caspase 9, 6, 12, parp, chop and pten. |
2020-02-25 |
2023-08-13 |
Not clear |
| Man Li, Duzhen Zhang, Jintao Cheng, Jiamei Liang, Fenghua Y. Ginsenoside Rh2 inhibits proliferation but promotes apoptosis and autophagy by down-regulating microRNA-638 in human retinoblastoma cells. Experimental and molecular pathology. vol 108. 2020-02-25. PMID:30853612. |
meanwhile, expression levels of proteins associated with cell cycle, apoptosis, autophagy and the phosphatidylinositol-3-kinase (pi3k)/akt/mechanistic target of rapamycin (mtor) pathway as well as p53 were measured by western blot analysis. |
2020-02-25 |
2023-08-13 |
human |
| Amira Thouri, Livia La Barbera, Lorena Canuti, Rolando Vegliante, Aicha Jelled, Guido Flamini, Maria Rosa Ciriolo, Lotfi Achou. Antiproliferative and apoptosis-inducing effect of common Tunisian date seed (var. Korkobbi and Arechti) phytochemical-rich methanolic extract. Environmental science and pollution research international. vol 26. issue 36. 2020-02-25. PMID:31721029. |
whereas, the cytotoxic effect was evaluated and apoptosis induction was confirmed by western blot technique (caspase-9, caspase-3, and parp-1). |
2020-02-25 |
2023-08-13 |
Not clear |
| Liang Yi, Dan Sun, Qian Han, Zhonghui Liu, Zeng Zeng, Yanping Wu, Xiaoyu Chai, Xinmin Li. Interferon regulatory factor 3 mediates Poly(I:C)-induced innate immune response and apoptosis in non‑small cell lung cancer. International journal of oncology. vol 52. issue 5. 2020-02-24. PMID:29512705. |
in the present study, western blot analysis, reverse transcription-quantitative polymerase chain reaction, rna interference, irf3 plasmid construction, elisa and apoptosis analysis were employed to study the innate immune response and apoptosis of non‑small cell lung cancer (nsclc) cells. |
2020-02-24 |
2023-08-13 |
Not clear |
| Ying-Ying Feng, Hai-Yu Ji, Xiao-Dan Dong, An-Jun Li. An alcohol-soluble polysaccharide from Atractylodes macrocephala Koidz induces apoptosis of Eca-109 cells. Carbohydrate polymers. vol 226. 2020-02-21. PMID:31582084. |
annexin v/pi assay, hoechst 33,258 staining, cell cycle distribution, rhodamine 123 dye assay and western blot assay clarified that apa could accelerate the apoptosis of eca109 cells by mitochondrial pathway and stocked cells at s phase. |
2020-02-21 |
2023-08-13 |
Not clear |
| Bao-Li Fei, Shuangyan Tu, Zuzhuang Wei, Pingping Wang, Jian-Ying Long, Chunhua Qiao, Zhen-Feng Che. Biological evaluation of optically pure chiral binuclear copper(ii) complexes based on a rosin derivative as highly potential anticancer agents. Dalton transactions (Cambridge, England : 2003). vol 48. issue 41. 2020-02-20. PMID:31465061. |
the western blot analysis results indicate that 1 might induce apoptosis through intrinsic and extrinsic pathways, autophagy and dna damage in mcf-7 cells. |
2020-02-20 |
2023-08-13 |
cattle |
| Nenghong Sun, Lichao Chu, Lei Yuan, Zongcai Q. Inactivation of P2YR12 contributes to isoflurane-induced neuronal injury by altering TLR-4/BDNF/TNF-α. Folia neuropathologica. vol 57. issue 2. 2020-02-20. PMID:31556575. |
apoptosis of neuronal cells was estimated by terminal deoxynucleotidyl transferase dutp nick end labelling (tunel) and western blot assays. |
2020-02-20 |
2023-08-13 |
rat |
| Hanli Fan, Jianbo Li, Jiwu Wang, Zange H. Long Non-Coding RNAs (lncRNAs) Tumor-Suppressive Role of lncRNA on Chromosome 8p12 (TSLNC8) Inhibits Tumor Metastasis and Promotes Apoptosis by Regulating Interleukin 6 (IL-6)/Signal Transducer and Activator of Transcription 3 (STAT3)/Hypoxia-Inducible Factor 1-alpha (HIF-1α) Signaling Pathway in Non-Small Cell Lung Cancer. Medical science monitor : international medical journal of experimental and clinical research. vol 25. 2020-02-20. PMID:31601776. |
we used flow cytometry to assess cell apoptosis, and cell autophagy was assessed by western blot analysis and immunofluorescence staining. |
2020-02-20 |
2023-08-13 |
human |
| Weiwei Zhu, Xin Zhang, Kun Gao, Xufang Wan. Effect of astragaloside IV and the role of nuclear receptor RXRα in human peritoneal mesothelial cells in high glucose‑based peritoneal dialysis fluids. Molecular medicine reports. vol 20. issue 4. 2020-02-19. PMID:31485615. |
cell viability, apoptosis and emt were examined using the cell counting kit‑8 assay and flow cytometry, and by determining the levels of caspase‑3, e‑cadherin and α‑smooth muscle actin (α‑sma) via western blot analysis. |
2020-02-19 |
2023-08-13 |
human |
| Xiaoliang Mei, Jian Tong, Wei Zhu, Yongliang Zh. lncRNA‑NR024118 overexpression reverses LPS‑induced inflammatory injury and apoptosis via NF‑κB/Nrf2 signaling in ATDC5 chondrocytes. Molecular medicine reports. vol 20. issue 4. 2020-02-19. PMID:31485657. |
expression of the cell apoptosis markers bcl‑2, bax, bcl‑2‑like protein 11, nf‑κb, phosphorylated (p)‑nf‑κb inhibitor β (iκbβ), iκbβ, p‑transcription factor p65 (p65) and p65, and nuclear factor erythroid‑2 related factor 2 (nrf2) signaling pathways‑associated proteins, nrf2, ho‑1 and quinone oxidoreductase‑1 were detected by western blot analysis and rt‑qpcr. |
2020-02-19 |
2023-08-13 |
cat |