| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sung-Hyun Kim, Eun-Seon Yoo, Joong-Seok Woo, So-Hee Han, Jae-Han Lee, Soo-Hyun Jung, Hyeong-Jin Kim, Ji-Youn Jun. Antitumor and apoptotic effects of quercetin on human melanoma cells involving JNK/P38 MAPK signaling activation. European journal of pharmacology. vol 860. 2020-01-08. PMID:31348906. |
expression of quercetin-induced apoptosis proteins was investigated by western blot analysis. |
2020-01-08 |
2023-08-13 |
mouse |
| Hala Soltana, Aline Pinon, Youness Limami, Younes Zaid, Loubna Khalki, Nabil Zaid, Driss Salah, Uteuliyev Yerzhan Sabitaliyevich, Alain Simon, Bertrand Liagre, Mohamed Hammam. Antitumoral activity of Ficus carica L. on colorectal cancer cell lines. Cellular and molecular biology (Noisy-le-Grand, France). vol 65. issue 6. 2020-01-08. PMID:31472041. |
we evaluated the effects of increasing concentrations of ficus carica extracts and latex on hct-116 and ht-29 human colorectal cell proliferation using mtt assay and apoptosis induction by evaluating parp cleavage by western blot analysis. |
2020-01-08 |
2023-08-13 |
human |
| Ning Han, Butian Zhang, Xin Wei, Lili Y. The inhibitory function of icariin in cell model of benign prostatic hyperplasia by upregulation of miR-7. BioFactors (Oxford, England). 2020-01-08. PMID:31785072. |
the cells proliferation, migration, apoptosis were tested by cck-8 assay, transwell assay, flow cytometry, and western blot. |
2020-01-08 |
2023-08-13 |
human |
| Qing Qing He, Xiao Wu, Xiao Peng Liu, Xiao Jian Yang, Zhong Min Yuan, Yan Zhan. 14-3-3 epsilon plays an important role in testicular germ cell apoptosis: A functional proteomic study of experimental varicocele. Andrologia. vol 51. issue 6. 2020-01-06. PMID:30950109. |
the expression of 14-3-3ε in rat testes was confirmed by western blot and immunohistochemistry, and the terminal deoxynucleotidyl transferase dutp nick end labelling (tunel) method was used to analyse the apoptosis of germ cells. |
2020-01-06 |
2023-08-13 |
rat |
| Xia Li, Naijin Zhang, Ying Zhang, Pengyu Jia, Yuxuan Guo, Yichen Tian, Shilong You, Shaojun Wu, Yingxian Su. E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1. Molecular medicine reports. vol 20. issue 2. 2020-01-06. PMID:31257502. |
to investigate the effects and interactions of the e3 ligase f‑box and wd repeat domain containing 7 (fbw7) and mcl1 apoptosis regulator, bcl2 family member (mcl‑1) in myocardial cells during oxidative stress, cell counting kit‑8, flow cytometry, western blot, reactive oxygen species and co‑immunoprecipitation assays were conducted. |
2020-01-06 |
2023-08-13 |
Not clear |
| Huannan Li, Xiaoren Cao, Xiongbing Chen, Xiaohong Yi, Jun Xia, Jilan Chen, Lan Yan. Bufadienolides induce apoptosis and autophagy by inhibiting the AKT signaling pathway in melanoma A‑375 cells. Molecular medicine reports. vol 20. issue 3. 2020-01-06. PMID:31322190. |
western blot analysis was used to evaluate the expression levels of proteins involved in the akt pathway that are associated with apoptosis and autophagy. |
2020-01-06 |
2023-08-13 |
Not clear |
| Ling Zhu, Qunli Wang, Yi Hu, Fan Wan. The Circadian Gene Per1 Plays an Important Role in Radiation-Induced Apoptosis and DNA Damage in Glioma. Asian Pacific journal of cancer prevention : APJCP. vol 20. issue 7. 2020-01-06. PMID:31350984. |
rt-pcr and western blot analysis bothrevealed decreased expression of chk2 and p53, which regulate dna damage and repair via the chk2-p53 pathway,and decreased expression of c-myc, which is related to cell apoptosis. |
2020-01-06 |
2023-08-13 |
human |
| Huagang Liang, Chao Wang, Kun Gao, Jian Li, Rui Ji. ΜicroRNA‑421 promotes the progression of non‑small cell lung cancer by targeting HOPX and regulating the Wnt/β‑catenin signaling pathway. Molecular medicine reports. vol 20. issue 1. 2019-12-30. PMID:31115507. |
in addition, mir‑421 inhibited nsclc cell apoptosis by flow cytometry apoptosis assay, as evidenced by anti‑apoptosis gene bcl‑2 and apoptosis gene cleaved caspase‑3 and cleaved parp using western blot assay. |
2019-12-30 |
2023-08-13 |
Not clear |
| Eun-Ae Kim, Eon-Gi Sung, In-Hwan Song, Joo-Young Kim, Hwa-Jung Sung, Ho-Yong Sohn, Jong-Yi Park, Tae-Jin Le. Neferine-induced apoptosis is dependent on the suppression of Bcl-2 expression via downregulation of p65 in renal cancer cells. Acta biochimica et biophysica Sinica. vol 51. issue 7. 2019-12-30. PMID:31187116. |
in addition, neferine induced apoptosis by downregulating bcl-2 and p65 expression in the other two kidney cancer cell lines determined by flow cytometry and western blot analysis. |
2019-12-30 |
2023-08-13 |
human |
| Eun-Ae Kim, Eon-Gi Sung, In-Hwan Song, Joo-Young Kim, Hwa-Jung Sung, Ho-Yong Sohn, Jong-Yi Park, Tae-Jin Le. Neferine-induced apoptosis is dependent on the suppression of Bcl-2 expression via downregulation of p65 in renal cancer cells. Acta biochimica et biophysica Sinica. vol 51. issue 7. 2019-12-30. PMID:31187116. |
finally, we observed that treatment with neferine induced apoptosis by inhibiting the nf-κb pathway through caspase-mediated cleavage of the p65 protein by western blot analysis. |
2019-12-30 |
2023-08-13 |
human |
| Jing-Wen Zhang, Ding-Qi Xu, Xi-Zeng Fen. The toxic effects and possible mechanisms of glyphosate on mouse oocytes. Chemosphere. vol 237. 2019-12-30. PMID:31352102. |
the protein expression levels of apoptosis factors (bax, bcl-2) and the mrna expression levels of apoptosis-related genes (bax, bcl-2, caspase3) were measured by western blot and qrt-pcr, respectively. |
2019-12-30 |
2023-08-13 |
mouse |
| Zeynep Banu Doğanlar, Metehan Uzun, Mehmet Akif Ovali, Ayten Dogan, Gulin Ongoren, Oğuzhan Doğanla. Melatonin attenuates caspase-dependent apoptosis in the thoracic aorta by regulating element balance and oxidative stress in pinealectomised rats. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. vol 44. issue 2. 2019-12-27. PMID:30058356. |
for this purpose, we analysed the cellular and molecular effects of melatonin deficiency or administration on oxidative stress, dna damage, molecular chaperone response, and apoptosis induction in ta tissues of pinealectomised rats using elisa, rapd, qrt-pcr, and western blot assays. |
2019-12-27 |
2023-08-13 |
rat |
| Yi-Chia Wu, Wei-Ting Wang, Su-Shin Lee, Yur-Ren Kuo, Ya-Chin Wang, Shih-Jung Yen, Mei-Yueh Lee, Jwu-Lai Ye. Glucagon-Like Peptide-1 Receptor Agonist Attenuates Autophagy to Ameliorate Pulmonary Arterial Hypertension through Drp1/NOX- and Atg-5/Atg-7/Beclin-1/LC3β Pathways. International journal of molecular sciences. vol 20. issue 14. 2019-12-27. PMID:31336911. |
western blot analysis was used to assess apoptosis, mitochondrial stress and autophagy markers. |
2019-12-27 |
2023-08-13 |
rat |
| Shu Zhu, Zhe Zhang, Lian-Qun Jia, Kai-Xuan Zhan, Li-Jun Wang, Nan Song, Yue Liu, Yan-Yan Cheng, Yong-Ju Yang, Le Guan, Dong-Yu Min, Guan-Lin Yan. Valproic acid attenuates global cerebral ischemia/reperfusion injury in gerbils via anti-pyroptosis pathways. Neurochemistry international. vol 124. 2019-12-24. PMID:30611759. |
in addition, western blot and real-time pcr analysis revealed that vpa modulated the protein expression of apoptosis repressor with caspase recruitment domain (arc), caspase-1 and il-1β/il-18. |
2019-12-24 |
2023-08-13 |
Not clear |
| Qinjian Xie, Lan Yu, Xin Wang, Zhengrong Wu, Dejuan Zhi, Jing Yang, Zhiwang Guo, Tao Wu, Yin Sun, Longhe Zhao, XiaoYu Ding, Akbar Khan, Hongyu L. A novel realgar-indigo naturalis formula more effectively induces apoptosis in NB4 cells. Pakistan journal of pharmaceutical sciences. vol 32. issue 3. 2019-12-24. PMID:31278706. |
we further study the effects of frbs on cell growth and apoptosis according flow cytometry, dna fragmentation assay and fluorescence microscopy and western blot. |
2019-12-24 |
2023-08-13 |
Not clear |
| Yulong Mao, Weiwei Zhang, Ronghe Zhang, Jinhua Zu. Alkannin restrains oral squamous carcinoma cell growth, migration and invasion by regulating microRNA-9/RECK axis. Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2019-12-24. PMID:31349748. |
then, brdu, flow cytometry, western blot and transwell assays were executed to appraise proliferation, apoptosis, migration and invasion in oscc cells with alk stimulation. |
2019-12-24 |
2023-08-13 |
Not clear |
| Min Zhang, Xueting Wang, Jing Yao, Zhaohui Qi. Long non-coding RNA NEAT1 inhibits oxidative stress-induced vascular endothelial cell injury by activating the miR-181d-5p/CDKN3 axis. Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2019-12-24. PMID:31352814. |
the potential role of neat1 in viability, migration and apoptosis was analyzed by cck-8, cell metastasis, flow cytometry, dual-luciferase reporter, rna immunoprecipitation and western blot assays using huvecs overexpressing neat1. |
2019-12-24 |
2023-08-13 |
mouse |
| Zhi Zuo, Peng-Fei Zuo, Zu-Long Sheng, Xin Wang, Jian-Dong Ding, Gen-Shan M. Tetramethylprazine attenuates myocardial ischemia/reperfusion injury through modulation of autophagy. Life sciences. vol 239. 2019-12-23. PMID:31678281. |
cell apoptosis were identified by flow cytometry and autophagy were detected by western blot. |
2019-12-23 |
2023-08-13 |
rat |
| Ping Chu, Lina Xu, Haiying S. HULC functions as an oncogene in ovarian carcinoma cells by negatively modulating miR-125a-3p. Journal of physiology and biochemistry. vol 75. issue 2. 2019-12-20. PMID:30863948. |
expression of proteins associated with cell cycle, apoptosis, and signaling pathways was determined by western blot assay. |
2019-12-20 |
2023-08-13 |
Not clear |
| Jin Wang, Yanjin Feng, Haiyan Huo, Xumei Zhang, Jiping Yue, Wenting Zhang, Zi Yan, Xiangying Jia. NLRP3 inflammasome mediates angiotensin II-induced islet β cell apoptosis. Acta biochimica et biophysica Sinica. vol 51. issue 5. 2019-12-20. PMID:30939192. |
the cell apoptosis was detected by flow cytometry and western blot analysis. |
2019-12-20 |
2023-08-13 |
rat |