| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fangjing Wei, Baojun Ren, Wei Han, Hong Guan, Guoqiang Jing, Min Wan. Investigate the Effect of miR-22 on the Apoptosis of Coronary Heart Disease Cells Through the Wnt-1 Pathway Based on Nano-Silica-Induced Rat Models. Journal of nanoscience and nanotechnology. vol 21. issue 2. 2021-06-10. PMID:33183481. |
we used flow cytometry to detect intracellular reactive oxygen species and apoptotic rates, and used western blot to detect the expression of proteins that affect apoptosis. |
2021-06-10 |
2023-08-13 |
rat |
| Rosalba Siracusa, Ramona D'Amico, Daniela Impellizzeri, Marika Cordaro, Alessio Filippo Peritore, Enrico Gugliandolo, Rosalia Crupi, Angela Trovato Salinaro, Emanuela Raffone, Tiziana Genovese, Salvatore Cuzzocrea, Roberta Fusco, Rosanna Di Paol. Autophagy and Mitophagy Promotion in a Rat Model of Endometriosis. International journal of molecular sciences. vol 22. issue 10. 2021-06-09. PMID:34064854. |
rapamycin was administered by activating autophagy and mitophagy, which increased apoptosis (assessed by western blot analysis of bcl-2, bax, and cleaved-caspase 3) and reduced angiogenesis (assessed by immunohistochemical analysis of vascular endothelial grow factor (vegf) and cd34) in the lesions. |
2021-06-09 |
2023-08-13 |
rat |
| Jianhong Wu, Lingge Jin, Yudi Zhang, Aihong Duan, Juhong Liu, Ziwen Jiang, Liang Huang, Jing Chen, Zhaohui Liu, Dan Lu, Yinmei Da. LncRNA HOTAIR promotes endometrial fibrosis by activating TGF-β1/Smad pathway. Acta biochimica et biophysica Sinica. vol 52. issue 12. 2021-06-08. PMID:33313721. |
we then performed rt-qpcr and western blot analysis, along with cell proliferation and apoptosis assays, to investigate the effects of hotair on the transdifferentiation of escs into myofibroblasts. |
2021-06-08 |
2023-08-13 |
Not clear |
| Songfeng Chen, Qing Tian, Chunfeng Shang, Lin Yang, Na Wei, Guowei Shang, Yanhui Ji, Hongwei Kou, Shitao Lu, Hongjian Li. Synergistic Utilization of Necrostatin-1 and Z-VAD-FMK Efficiently Promotes the Survival of Compression-Induced Nucleus Pulposus Cells via Alleviating Mitochondrial Dysfunction. BioMed research international. vol 2020. 2021-06-08. PMID:33376733. |
autophagy and apoptosis levels were evaluated by western blot and quantified by flow cytometry after monodansylcadaverine and annexin v-fitc/propidium iodide staining, respectively. |
2021-06-08 |
2023-08-13 |
Not clear |
| Yang Shen, Chengjun Xue, Guoli You, Cui Li. miR-9 alleviated the inflammatory response and apoptosis in caerulein-induced acute pancreatitis by regulating FGF10 and the NF-κB signaling pathway. Experimental and therapeutic medicine. vol 22. issue 2. 2021-06-08. PMID:34093751. |
furthermore, caerulein-induced apoptosis was reported by flow cytometry and western blot assays. |
2021-06-08 |
2023-08-13 |
Not clear |
| Yuan-Yuan Jia, Yue Yu, Hong-Jun L. POSTN promotes proliferation and epithelial-mesenchymal transition in renal cell carcinoma through ILK/AKT/mTOR pathway. Journal of Cancer. vol 12. issue 14. 2021-06-08. PMID:34093819. |
the effects of postn on cell viability, apoptosis, migration, invasion and epithelial-to-mesenchymal transition (emt) of rcc cells were determined by cck-8, flow cytometry, migration and invasion assay and western blot analysis. |
2021-06-08 |
2023-08-13 |
Not clear |
| Peng Lin, Boliang Zhou, Haiying Yao, Ya-Ping Gu. Effect of carboplatin injection on Bcl-2 protein expression and apoptosis induction in Raji cells. European journal of histochemistry : EJH. vol 64. issue 3. 2021-06-07. PMID:32643899. |
for each group, the relative expression of b-cell lymphoma-2 (bcl-2) was determined by western blot (wb), the expression pattern of bcl-2 was observed by immunocytochemistry (icc), and cell apoptosis was observed after hoechst 33342 staining. |
2021-06-07 |
2023-08-13 |
human |
| Azam Rashidbaghan, Ali Mostafaie, Yaghoub Yazdani, Kamran Mansour. Urtica dioica agglutinin (a plant lectin) has a caspase-dependent apoptosis induction effect on the acute lymphoblastic leukemia cell line. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 6. 2021-06-07. PMID:33040797. |
distribution of cell cycle phases was determined by pi staining and apoptosis was examined with annexin v/pi and western blot. |
2021-06-07 |
2023-08-13 |
human |
| Lingfei Zhu, Xiaohan Huang, Zhenhua Li, Gang Cao, Xuanjin Zhu, Shaohua She, Tenghao Huang, Gang L. Evaluation of hepatotoxicity induced by 2-ethylhexyldiphenyl phosphate based on transcriptomics and its potential metabolism pathway in human hepatocytes. Journal of hazardous materials. vol 413. 2021-06-07. PMID:33582465. |
western blot, apoptosis detection, glycolysis stress test, and cell cycle analysis were further performed to verify the above main pathways. |
2021-06-07 |
2023-08-13 |
human |
| Wensi Chen, Shiping He, Daoman Xian. Hypoxia-induced retinal pigment epithelium cell-derived bFGF promotes the migration and angiogenesis of HUVECs through regulating TGF-β1/smad2/3 pathway. Gene. vol 790. 2021-06-07. PMID:33964379. |
after cell culture in hypoxia conditions, the cell viability, apoptosis, and the expressions of bfgf and vascular endothelial growth factor a (vegfa) in human rpes were detected by 3-(4, 5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt), flow cytometry, western blot, rt-qpcr, or elisa. |
2021-06-07 |
2023-08-13 |
human |
| Venkatesh Ravula, Yu-Lun Lo, Yi-Ting Wu, Chien-Wen Chang, Srilakshmi V Patri, Li-Fang Wan. Arginine-tocopherol bioconjugated lipid vesicles for selective pTRAIL delivery and subsequent apoptosis induction in glioblastoma cells. Materials science & engineering. C, Materials for biological applications. vol 126. 2021-06-07. PMID:34082988. |
the expression of trail protein regulated death receptor and apoptosis signaling pathway is assayed by western blot using transfection of at-based/ptrail into u87 cell lines. |
2021-06-07 |
2023-08-13 |
Not clear |
| Wan-Long Xu, Dilimulati Aikeremu, Jun-Gang Sun, Yan-Jun Zhang, Jiang-Bo Xu, Wen-Zheng Zhou, Xi-Bin Zhao, Hao Wang, Hong Yua. Effect of intensity-modulated radiation therapy on sciatic nerve injury caused by echinococcosis. Neural regeneration research. vol 16. issue 3. 2021-06-04. PMID:32985491. |
additionally, apoptosis of neurons was examined using a terminal-deoxynucleotidyl transferase-mediated dutp nick end labeling assay, and expression of bcl-2 and bax in sciatic nerve tissue was detected by immunohistochemical staining and western blot assay. |
2021-06-04 |
2023-08-13 |
Not clear |
| Yahong Liu, Ying Cheng, Wei Zhang, Hongqi Tia. Neuroprotective Effect of a New Free Radical Scavenger HL-008 in an Ischemia-Reperfusion Injury Rat Model. Neuroscience. vol 465. 2021-06-04. PMID:33915200. |
2,3,5-triphenyltetrazolium chloride and hematoxylin and eosin staining, immunofluorescence, western blot, and proteomics were used to evaluate the infarction volume, brain tissue morphology, apoptosis, inflammation, and related pathways. |
2021-06-04 |
2023-08-13 |
rat |
| Xiaolin Xia, Junlian Wang, Qifang Li. Effect of total flavones of Clematis filamentosa Dunn on the oxLDL-induced injury of vascular smooth muscle cells by regulating miR-455-5p. Cellular and molecular biology (Noisy-le-Grand, France). vol 66. issue 5. 2021-06-03. PMID:33040830. |
the expressions of inflammatory factors il-1β and tnf-α were analyzed by elisa, the apoptosis was evaluated by flow cytometry, the expression of bcl-2 and bax was determined by western blot, and the real-time fluorescence quantitative pcr (qrt-pcr) was applied to detect mir-455-5p expression. |
2021-06-03 |
2023-08-13 |
Not clear |
| Chuan Jiang, Ning Dong, Jianli Feng, Maolin Ha. MiRNA-190 exerts neuroprotective effects against ischemic stroke through Rho/Rho-kinase pathway. Pflugers Archiv : European journal of physiology. vol 473. issue 1. 2021-06-03. PMID:33196911. |
quantitative real-time polymerase chain reaction (qrt-pcr), nissl staining, flow cytometry, and western blot were conducted to examine the expression of mir-190 and cell apoptosis in different groups. |
2021-06-03 |
2023-08-13 |
rat |
| Yunxia Han, Zhenzhi M. LncRNA highly upregulated in liver cancer regulates imatinib resistance in chronic myeloid leukemia via the miR-150-5p/MCL1 axis. Anti-cancer drugs. vol 32. issue 4. 2021-06-03. PMID:33587348. |
cell apoptosis was monitored by flow cytometry and western blot. |
2021-06-03 |
2023-08-13 |
Not clear |
| Zi Liu, Binyue Lang, Minghuan Gao, Xing Chang, Qi Guan, Qile Xu, Di Wu, Zengqiang Li, Daiying Zuo, Weige Zhang, Yingliang W. 3-(3-Methoxyphenyl)-6-(3-amino-4-methoxyphenyl)-7H-[1,2,4] triazolo [3,4-b][1,3,4] thiadiazine, a novel tubulin inhibitor, evokes G2/M cell cycle arrest and apoptosis in SGC-7901 and HeLa cells. Journal of cellular biochemistry. vol 121. issue 3. 2021-06-02. PMID:31642107. |
in further study, mitochondrial membrane potential analysis and western blot analysis demonstrated that xsd-7 treatment-induced sgc-7901 cell apoptosis via both the mitochondria-mediated pathway and the death receptor-mediated pathway. |
2021-06-02 |
2023-08-13 |
human |
| Dukanya, Muthu K Shanmugam, Shobith Rangappa, Prashant K Metri, Surender Mohan, Basappa, Kanchugarakoppal S Rangapp. Exploring the newer oxadiazoles as real inhibitors of human SIRT2 in hepatocellular cancer cells. Bioorganic & medicinal chemistry letters. vol 30. issue 16. 2021-06-01. PMID:32631535. |
among the tested otds, compound 2-(4-methoxyphenyl)-5-(1-methyl-1h-indazol-3-yl)-1,3,4-oxadiazole was found to inhibit the catalytical activity of sirt2 and brings about apoptosis as shown by western blot analysis and flow cytometry data. |
2021-06-01 |
2023-08-13 |
human |
| Fan Hu, Liang Shao, Ji Zhang, Hong Zhang, An Wen, Ping Zhan. Knockdown of ZFAS1 Inhibits Hippocampal Neurons Apoptosis and Autophagy by Activating the PI3K/AKT Pathway via Up-regulating miR-421 in Epilepsy. Neurochemical research. vol 45. issue 10. 2021-06-01. PMID:32725369. |
hippocampal neurons viability, apoptosis and autophagy were analyzed via cell counting kit-8, flow cytometry and western blot. |
2021-06-01 |
2023-08-13 |
mouse |
| Yuanwu Cao, Chang Jiang, Haodong Lin, Zixian Che. Silencing of Long Noncoding RNA Growth Arrest-Specific 5 Alleviates Neuronal Cell Apoptosis and Inflammatory Responses Through Sponging microRNA-93 to Repress PTEN Expression in Spinal Cord Injury. Frontiers in cellular neuroscience. vol 15. 2021-06-01. PMID:34054430. |
western blot analysis of the apoptosis regulator protein and terminal deoxynucleotidyl transferase dutp nick end labeling assay was conducted to evaluate neuron cell apoptosis. |
2021-06-01 |
2023-08-13 |
mouse |