| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Cai, Youdong Zhou, Zhiyong Wang, Yaozu Zh. Neuroserpin extends the time window of tPA thrombolysis in a rat model of middle cerebral artery occlusion. Journal of biochemical and molecular toxicology. vol 34. issue 11. 2021-06-23. PMID:32659866. |
the expression of caspase-3 and bcl-2 in brain tissue and apoptosis of neurons were examined by western blot analysis and toluidine blue staining. |
2021-06-23 |
2023-08-13 |
rat |
| Zhenkui Zuo, Shuling Ji, Lulu He, Yage Zhang, Zining Peng, Jiarui Ha. LncRNA TTN-AS1/miR-134-5p/PAK3 axis regulates the radiosensitivity of human large intestine cancer cells through the P21 pathway and AKT/GSK-3β/β-catenin pathway. Cell biology international. vol 44. issue 11. 2021-06-23. PMID:32749739. |
ttn-as1 expression was evaluated by reverse-transcription quantitative polymerase chain reaction, western blot, and cellular immunofluorescence, and flow cytometry analysis was used to measure apoptosis. |
2021-06-23 |
2023-08-13 |
human |
| Shu Wang, Yuqing Huang, Guangyan Luo, Xin Yang, Wei Huan. Cyanidin-3-O-glucoside attenuates high glucose-induced podocyte dysfunction by inhibiting apoptosis and promoting autophagy via activation of SIRT1/AMPK pathway. Canadian journal of physiology and pharmacology. vol 99. issue 6. 2021-06-22. PMID:33049148. |
mtt, flow cytometry assay, and western blot analysis showed that c3g could reverse the increase of cell apoptosis under high glucose treatment in mpc5 cells by upregulation of |
2021-06-22 |
2023-08-13 |
Not clear |
| Jing Lin, Shasha Liao, Zewa Liu, E Li, Xiaohua Wu, Wanting Zen. LncRNA FGD5-AS1 accelerates cell proliferation in pancreatic cancer by regulating miR-520a-3p/KIAA1522 axis. Cancer biology & therapy. vol 22. issue 3. 2021-06-22. PMID:33794727. |
colony formation assay, edu assay, flow cytometry assay and transwell assay as well as western blot were adopted to test the cell abilities of proliferation, apoptosis and migration, separately. |
2021-06-22 |
2023-08-13 |
Not clear |
| Changliang Huo, Li Wang, Qiuli Wang, Yanbo Yang, Bo Che. Hydroxysafflor Yellow A inhibits the viability and migration of vascular smooth muscle cells induced by serum from rats with chronic renal failure via inactivation of the PI3K/Akt signaling pathway. Experimental and therapeutic medicine. vol 22. issue 2. 2021-06-22. PMID:34149896. |
flow cytometry analysis was performed to assess apoptosis, and western blot analysis was performed to detect protein expression levels of pi3k and akt. |
2021-06-22 |
2023-08-13 |
human |
| Lei Wang, Longning Wang, Qingfen Wang, Bahman Yosefi, Sen Wei, Xiaodong Wang, Daqing She. The function of long noncoding RNA HOTAIRM1 in the progression of prostate cancer cells. Andrologia. vol 53. issue 2. 2021-06-21. PMID:33368390. |
cell apoptosis was analysed using flow cytometry and wnt pathway-related proteins by western blot. |
2021-06-21 |
2023-08-13 |
Not clear |
| Jiao Xu, Zhi-Cheng Tan, Zhong-Yuan Shen, Xing-Jia Shen, Shun-Ming Tan. Cordyceps cicadae polysaccharides inhibit human cervical cancer hela cells proliferation via apoptosis and cell cycle arrest. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 148. 2021-06-21. PMID:33421460. |
rt-qpcr and western blot were used to study the mrna and protein expression of genes related to cell cycle and apoptosis signaling pathway. |
2021-06-21 |
2023-08-13 |
human |
| Xin-Xian Xu, Gang Zheng, Shang-Kun Tang, Hai-Xiao Liu, Yue-Zheng Hu, Ping Shan. Theaflavin protects chondrocytes against apoptosis and senescence Food & function. vol 12. issue 4. 2021-06-21. PMID:33471008. |
then, according to western blot, live-dead staining, and sa-β-gal staining, the dramatically increased level of apoptosis and senescence of chondrocytes in response to tbhp was also found to be reduced by tf administration. |
2021-06-21 |
2023-08-13 |
mouse |
| Daisuke Harama, Takashi Yahata, Keiko Kagami, Masako Abe, Norie Ando, Shin Kasai, Minori Tamai, Koshi Akahane, Takeshi Inukai, Nobutaka Kiyokawa, Abd Aziz Ibrahim, Kiyoshi Ando, Kanji Sugit. IMiDs uniquely synergize with TKIs to upregulate apoptosis of Philadelphia chromosome-positive acute lymphoblastic leukemia cells expressing a dominant-negative IKZF1 isoform. Cell death discovery. vol 7. issue 1. 2021-06-19. PMID:34117218. |
analyses of flow cytometry, western blot, and oligonucleotide array revealed that apoptosis was caspase-/p53-dependent and associated with upregulation of pro-apoptotic bax/bim, enhanced dephosphorylation of bcr-abl/akt, and downregulation of oncogenic helicase genes hills, cdc6, and mcms4 and 8. |
2021-06-19 |
2023-08-13 |
mouse |
| Dandan Shao, Jiayong Zhang, Le Tang, Qiuli Yu, Xiaoxiao Hu, Qin Ruan, Wei Ouyang, Zigui Zhan. Effects and Molecular Mechanism of L-Type Calcium Channel on Fluoride-Induced Kidney Injury. Biological trace element research. vol 197. issue 1. 2021-06-18. PMID:31792773. |
the apoptosis of kidney cell was observed by tunel, and the protein expression levels of cav1.2 and cam, camkii, bcl-2, and bax were detected by western blot. |
2021-06-18 |
2023-08-13 |
mouse |
| Jie Ai, Hongyan Wang, Peng Chu, Abdullah Shopit, Mengyue Niu, Nisar Ahmad, Tsehaye Tesfaldet, Fu Han Wang, Jia Ni Fang, Xiaodong Li, Shi Jie Tang, Qing Ju Han, Guozhu Han, Jinyong Peng, Zeyao Tan. The neuroprotective effects of phosphocreatine on Amyloid Beta 25-35-induced differentiated neuronal cell death through inhibition of AKT /GSK-3β /Tau/APP /CDK5 pathways in vivo and vitro. Free radical biology & medicine. vol 162. 2021-06-18. PMID:33131696. |
besides, the apoptosis pathway was detected using western blot, showing that pcr could significantly reduce caspase-3, caspase-9, bcl-2/bax expression in vivo and in vitro. |
2021-06-18 |
2023-08-13 |
mouse |
| Yue Zhou, Lian-Jun Cai, Li-Hui Xu, Yu Guo, Nuo Chen, Qing Ya. The role of sirt1 in the retinal ganglion cells cultured by high glucose. International ophthalmology. vol 41. issue 3. 2021-06-18. PMID:33174070. |
after 48 h of infection, the viability of rgc was detected by cck8 kit, the apoptosis rate was detected by fcm analysis, and the protein expression of p53, foxo3a, nf-κ b, caspase-3 was detected by western blot. |
2021-06-18 |
2023-08-13 |
Not clear |
| Zengjia Liu, Guiju Hu, Yan Zhao, Zuorun Xiao, Mingzhe Yan, Mei Re. Silence of cZNF292 suppresses the growth, migration, and invasion of human esophageal cancer Eca-109 cells via upregulating miR-206. Journal of cellular biochemistry. vol 121. issue 3. 2021-06-17. PMID:31680303. |
various kinds of factors, which are involved in cell development including proliferation, apoptosis, migration, and invasion were determined by western blot analysis. |
2021-06-17 |
2023-08-13 |
human |
| Han Liu, Xuekai Xiong, Tingting Zhu, Yifan Zhu, Yongchong Peng, Xiaojie Zhu, Jieru Wang, Huanchun Chen, Yingyu Chen, Aizhen Gu. Differential nitric oxide induced by Mycobacterium bovis and BCG leading to dendritic cells apoptosis in a caspase dependent manner. Microbial pathogenesis. vol 149. 2021-06-17. PMID:32504845. |
in addition, bcg induced significantly higher levels of apoptosis in dcs compared to m.bovis shown by higher levels of dna fragmentation using flow cytometry and release of mitochondrial cytochrome c, and up-regulation of the genes caspase-3, caspase-8, caspase-9 and dffa critical to apoptosis by qrt-pcr detection and western blot analysis. |
2021-06-17 |
2023-08-13 |
Not clear |
| Li Wu, Yuncheng Lv, Ying Lv, Sunmin Xiang, Zhibo Zhao, Ziqing Tang, Linling Ou, Bin Yan, Xinhua Xiao, Gebo Wen, Renxian Cao, Jing Yan. A novel secretagogin/ATF4 pathway is involved in oxidized LDL-induced endoplasmic reticulum stress and islet β-cell apoptosis. Acta biochimica et biophysica Sinica. vol 53. issue 1. 2021-06-17. PMID:33289795. |
in this study, min6 cells were treated with oxidized low-density lipoprotein (ox-ldl) for 24 h, and then intracellular lipid droplets and cell apoptosis were quantified, and scgn and er stress markers were identified by western blot analysis. |
2021-06-17 |
2023-08-13 |
Not clear |
| Jia-Fei Liu, Dong Guo, En-Ming Kang, Yu-Shan Wang, Xiao-Zhong Gao, Hai-Yan Cong, Peng Liu, Nai-Qian Zhang, Ming-Yi Wan. Acute and chronic infection of H. pylori caused the difference in apoptosis of gastric epithelial cells. Microbial pathogenesis. vol 150. 2021-06-17. PMID:33421608. |
apoptosis of these two models were analyzed by flow cytometry compared with the control cells, meanwhile, apoptosis associated markers (bcl-xl, bcl-2, bax, etc) were detected by western blot, additional in clinical h. pylori-positive gastric cancer tissues. |
2021-06-17 |
2023-08-13 |
Not clear |
| Hussein Chehade, Alexandra Fox, Gil G Mor, Ayesha B Alver. Determination of Caspase Activation by Western Blot. Methods in molecular biology (Clifton, N.J.). vol 2255. 2021-06-16. PMID:34033089. |
detection of caspase cleavage by western blot analysis is a conventional method to demonstrate the induction of apoptosis. |
2021-06-16 |
2023-08-13 |
Not clear |
| Hussein Chehade, Alexandra Fox, Gil G Mor, Ayesha B Alver. Determination of Caspase Activation by Western Blot. Methods in molecular biology (Clifton, N.J.). vol 2255. 2021-06-16. PMID:34033089. |
in the context of apoptosis, the proper analysis of western blot results depends on the understanding of the mechanisms and outcomes of caspase processing during the course of its activation. |
2021-06-16 |
2023-08-13 |
Not clear |
| Hussein Chehade, Alexandra Fox, Gil G Mor, Ayesha B Alver. Determination of Caspase Activation by Western Blot. Methods in molecular biology (Clifton, N.J.). vol 2255. 2021-06-16. PMID:34033089. |
in this chapter, we describe the step-by-step methodology in the western blot analysis of caspase cleavage during apoptosis. |
2021-06-16 |
2023-08-13 |
Not clear |
| Chau Wei Wong, Yangbin Xu, Xiangxia Liu, Shuqia Xu, Yi Zhang, Zhaowei Zhu, Bo H. Effect of Induction Time on the Proliferation and Differentiation of Induced Schwann-Like Cells from Adipose-Derived Stem Cells. Cellular and molecular neurobiology. vol 40. issue 7. 2021-06-11. PMID:32062800. |
western blot analyses of caspase-3/cleaved caspase-3 and fcm were applied to assess cell apoptosis. |
2021-06-11 |
2023-08-13 |
rat |