| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyan Wang, Haiying Bao, Tolgor Ba. Investigation of the possible mechanism of polysaccharides extracted from Leucocalocybe mongolica in exerting antitumor effects in H22 tumor-bearing mice. Journal of food biochemistry. vol 45. issue 4. 2021-07-08. PMID:33569819. |
in this research, the lmp structure was analyzed, and the immunohistochemical and western blot analysis confirmed that, lmp could effectively reduce the generation of tumor angiogenesis, promote apoptosis of tumor cell sand inhibit tumor growth. |
2021-07-08 |
2023-08-13 |
mouse |
| Wei Chen, Ping Zheng, Tao Hong, Yang Wang, Ning Liu, Bin He, Shufeng Zou, Dabin Ren, Jian Duan, Lin Zhao, Jiugeng Fen. Astrocytes-derived exosomes induce neuronal recovery after traumatic brain injury via delivering gap junction alpha 1-20 k. Journal of tissue engineering and regenerative medicine. vol 14. issue 3. 2021-07-07. PMID:31826322. |
immunofluorescence staining, tunnel, western blot were employed to detect exosomes marker cd60, apoptosis, and mitochondrial function related protein expression and gja1-20 k in cell culture. |
2021-07-07 |
2023-08-13 |
rat |
| Pan Liu, Qian Ying, Huan Liu, Si-Qi Yu, Lu-Ping Bu, Liang Shao, Xin-Yi L. Curcumin enhances anti‑cancer efficacy of either gemcitabine or docetaxel on pancreatic cancer cells. Oncology reports. vol 44. issue 4. 2021-07-06. PMID:32945513. |
furthermore, the results from transmission electron microscope, dapi staining experiments and western blot analysis revealed that curcumin may trigger apoptosis of pc cells via parp/caspase‑3 signaling pathway and reinforced pro‑apoptotic ability of either gemcitabine or docetaxel. |
2021-07-06 |
2023-08-13 |
human |
| Tao Song, Pingping Wang, Lihong Xi. LncRNA TUG1 Contributes to Hypoxia-Induced Myocardial Cell Injury Through Downregulating miR-29a-3p in AC16 Cells. Journal of cardiovascular pharmacology. vol 76. issue 5. 2021-07-06. PMID:33165134. |
cell viability, apoptosis, and lactate dehydrogenase (ldh) release were detected by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, flow cytometry, western blot assay, and ldh cytotoxicity assay. |
2021-07-06 |
2023-08-13 |
human |
| Zuzana Andrejčáková, Radoslava Vlčková, Drahomíra Sopková, Katarzyna Kozioł, Marek Koziorowski, Dušan Fabián, Zuzana Šefčíková, Katarína Holovská, Viera Almášiová, Alexander V Sirotki. Dietary flaxseed's protective effects on body tissues of mice after oral exposure to xylene. Saudi journal of biological sciences. vol 28. issue 7. 2021-07-06. PMID:34220233. |
clinical examination, spectroscopic analysis of tissue aminotransferases, total lactate dehydrogenase (tldh), and acetylcholinesterase (ache) activities, electrophoretic analysis of ldh isoenzymes, western blot and immunohistochemical analysis of apoptosis as well as routine histology of the kidneys and jejunum, and transmission electron microscopy of the liver were performed. |
2021-07-06 |
2023-08-13 |
mouse |
| Yumeng Wu, Wei Xiu, Yubo W. Salvianolic Acid A Protects H9C2 Cardiomyocytes from Doxorubicin-Induced Damage by Inhibiting NFKB1 Expression Thereby Downregulating Long-Noncoding RNA (lncRNA) Plasmacytoma Variant Translocation 1 (PVT1). Medical science monitor : international medical journal of experimental and clinical research. vol 27. 2021-07-03. PMID:34153024. |
material and methods h9c2 cardiomyocytes exposed to dox were treated with sala or not, and then cell viability, apoptosis, and the expression of nuclear factor-kappab (nf-kappab) signaling were detected by cell counting kit-8, tunel staining, and western blot assays, respectively. |
2021-07-03 |
2023-08-13 |
Not clear |
| Sunli Hu, Chenxi Zhang, Tianchen Qian, Yue Bai, Liang Chen, Jiaoxiang Chen, Chongan Huang, Chenglong Xie, Xiangyang Wang, Haiming Ji. Promoting Nrf2/Sirt3-Dependent Mitophagy Suppresses Apoptosis in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration. Oxidative medicine and cellular longevity. vol 2021. 2021-07-03. PMID:34211633. |
western blot and tunel staining were used to examine apoptosis. |
2021-07-03 |
2023-08-13 |
Not clear |
| Yang Yao, Yinglei Xu, Yong Wan. Protective roles and mechanisms of rosmarinic acid in cyclophosphamide-induced premature ovarian failure. Journal of biochemical and molecular toxicology. vol 34. issue 12. 2021-07-02. PMID:32711407. |
the expression of apoptosis markers of cytochrome c and caspase-3 was also detected by western blot analysis and immunohistochemistry. |
2021-07-02 |
2023-08-13 |
mouse |
| Zhibing Wang, Zongdan Jiang, Jin Zhou, Zheng Li. circRNA RNF111 regulates the growth, migration and invasion of gastric cancer cells by binding to miR‑27b‑3p. International journal of molecular medicine. vol 46. issue 5. 2021-07-02. PMID:33000178. |
in addition, western blot analysis was performed to determine the expression levels of genes related to cell apoptosis and epithelial‑mesenchymal transition (emt). |
2021-07-02 |
2023-08-13 |
Not clear |
| Lingshan Xu, Liang Zhu, Ping Liu, Zhouquan Wu, Zhiqing Zo. Ozone induces tolerance against cardiomyocytes oxygen-glucose deprivation/reperfusion through inhibition of autophagy pathway. Experimental and therapeutic medicine. vol 22. issue 2. 2021-07-02. PMID:34194547. |
the expressions of apoptosis regulator b-cell lymphoma-2 (bcl-2), bcl-2 associated x protein (bax), cleaved caspase-3, markers of autophagy microtuble-associated protein 1 light chain 3 (lc3), autophagy-related protein 5 (atg5) and beclin-1 were measured by western blot analysis. |
2021-07-02 |
2023-08-13 |
rat |
| Jiaxing Dai, Shancai Xu, Takeshi Okada, Yu Liu, Gang Zuo, Jiping Tang, John H Zhang, Huaizhang Sh. T0901317, an Agonist of Liver X Receptors, Attenuates Neuronal Apoptosis in Early Brain Injury after Subarachnoid Hemorrhage in Rats via Liver X Receptors/Interferon Regulatory Factor/P53 Upregulated Modulator of Apoptosis/Dynamin-1-Like Protein Pathway. Oxidative medicine and cellular longevity. vol 2021. 2021-07-02. PMID:34194609. |
the severity of sah, neurobehavior test in both short- and long-term and apoptosis was measured with western blot and immunofluorescence staining. |
2021-07-02 |
2023-08-13 |
rat |
| Jing Wang, Jing Huang, Lili Huan. TSPAN1 silencing protects against cerulein-induced pancreatic acinar cell injury via targeting AGR2. Drug development research. 2021-07-02. PMID:34212407. |
western blot was performed to determine the expressions of proteins related to endoplasmic reticulum (er) stress and apoptosis. |
2021-07-02 |
2023-08-13 |
Not clear |
| Yuxi Tian, Ying Wang, Fujun Li, Junwen Yang, Yan Xu, Miao Ouyan. LncRNA TUG1 regulates the balance of HuR and miR-29b-3p and inhibits intestinal epithelial cell apoptosis in a mouse model of ulcerative colitis. Human cell. vol 34. issue 1. 2021-07-01. PMID:33047284. |
cell apoptosis was assessed by flow cytometry and western blot analysis of apoptosis-related proteins. |
2021-07-01 |
2023-08-13 |
mouse |
| Xifeng Yang, Yao Sun, Ying Zhang, Shan Ha. Downregulation of miR‑181b inhibits human colon cancer cell proliferation by targeting CYLD and inhibiting the NF‑κB signaling pathway. International journal of molecular medicine. vol 46. issue 5. 2021-06-30. PMID:32901872. |
the expression levels of proteins associated with the nf‑κb signaling pathway and apoptosis were detected by western blot analysis. |
2021-06-30 |
2023-08-13 |
mouse |
| Xin Zhou, Chunlin Ke, You Lv, Caihong Ren, Tiansheng Lin, Feng Dong, Yanjun M. Asiaticoside suppresses cell proliferation by inhibiting the NF‑κB signaling pathway in colorectal cancer. International journal of molecular medicine. vol 46. issue 4. 2021-06-29. PMID:32945376. |
cell apoptosis and cell cycle were monitored by flow cytometry, and the expression of genes was evaluated using rt‑qpcr and western blot analysis. |
2021-06-29 |
2023-08-13 |
mouse |
| Fu-I Tung, Li-Chin Chen, Yu-Chi Wang, Ming-Hong Chen, Pei-Wei Shueng, Tse-Ying Li. Using a Hybrid Radioenhancer to Discover Tumor Cell-targeted Treatment for Osteosarcoma: An In Vitro Study. Current medicinal chemistry. vol 28. issue 19. 2021-06-29. PMID:33213306. |
this was supported by performing a western blot that confirmed the expression of cytochrome c (a marker of cell mitochondria damage) and caspase-3 (a marker of cell apoptosis). |
2021-06-29 |
2023-08-13 |
Not clear |
| Shaoxuan Zhang, Boxing Sun, Dali Wang, Ying Liu, Jing Li, Jiajia Qi, Yonghong Zhang, Chunyan Bai, Shuang Lian. Chlorogenic Acid Ameliorates Damage Induced by Fluorene-9-Bisphenol in Porcine Sertoli Cells. Frontiers in pharmacology. vol 12. 2021-06-29. PMID:34177588. |
transcriptome analysis and further real-time quantitative pcr and western blot results showed that bpfl exposure induced endoplasmic reticulum stress and apoptosis. |
2021-06-29 |
2023-08-13 |
Not clear |
| Yuhua He, Jiaqi Chen, Qiyue Zhang, Jialong Zhang, Lulai Wang, Xiaoxia Chen, Adrian J Molenaar, Xuezhao Su. α-Chaconine Affects the Apoptosis, Mechanical Barrier Function, and Antioxidant Ability of Mouse Small Intestinal Epithelial Cells. Frontiers in plant science. vol 12. 2021-06-29. PMID:34177990. |
in this study, mouse small intestinal epithelial cells were incubated with α-chaconine at 0, 0.4, and 0.8 μg/ml for 24, 48, and 72 h to examine apoptosis, mechanical barrier function, and antioxidant ability of the cells using a cell metabolic activity assay, flow cytometry, western blot, immunofluorescence, and fluorescence quantitative pcr. |
2021-06-29 |
2023-08-13 |
mouse |
| Mei Ge, Xuehan Bai, Aoyi Liu, Lingjuan Liu, Jie Tian, Tiewei L. An eIF3a gene mutation dysregulates myocardium growth with left ventricular noncompaction via the p-ERK1/2 pathway. Genes & diseases. vol 8. issue 4. 2021-06-29. PMID:34179316. |
cell proliferation, apoptosis, cell migration, and differentiation, as well as phosphorylation of erk1/2 were studied and were measured by proliferation assays, flow cytometry, real-time pcr and western blot, respectively. |
2021-06-29 |
2023-08-13 |
human |
| Yang Chen, Lingyan Wang, Xindi Lin, Qian Zhang, Yunchao Xu, Donghong Lin, Jianping Xu, Shangyuan Feng, Jianda H. Cytological and spectroscopic characteristics of c-KIT N822K mutation in core binding factor acute myeloid leukemia cells. Journal of biophotonics. vol 13. issue 8. 2021-06-23. PMID:32390317. |
the current work used common assays including cell cycle, apoptosis, clone formation and western blot to perform cytological detection for hl60 (wild type), nb4 (carrying t[15;17] chromosome translocation) and kasumi-1 (with c-kit n822k mutation); and meanwhile, the laser tweezers raman spectroscopy (ltrs) was also used to perform label-free detection of single living cells. |
2021-06-23 |
2023-08-13 |
Not clear |