| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chuan He, Caixia Su, Wentong Zhang, Qi Wa. miR-485-5p alleviates Alzheimer's disease progression by targeting PACS1. Translational neuroscience. vol 12. issue 1. 2021-10-02. PMID:34594577. |
moreover, cck-8 assay, flow cytometric analysis, and western blot analysis suggested that mir-485-5p overexpression promoted pericyte viability and prohibited pericyte apoptosis in app/ps1 mice. |
2021-10-02 |
2023-08-13 |
mouse |
| Yan Fang, Zhitang Chang, Zhicheng Xu, Jing Hu, Haiwen Zhou, Songping Yu, Xuan Wa. Osteoglycin silencing exerts inhibitory effects on myocardial fibrosis and epithelial/endothelial-mesenchymal transformation in a mouse model of myocarditis. BioFactors (Oxford, England). vol 46. issue 6. 2021-10-01. PMID:33141515. |
expression of ogn and wnt signaling pathway-related factors were measured by reverse transcription quantitative polymerase chain reaction and western blot assay, cell viability by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay, and cell cycle distribution and apoptosis by flow cytometry. |
2021-10-01 |
2023-08-13 |
mouse |
| Quan-Wen Liu, Yong Chen, Jing-Yuan Li, Ling Xiao, Wen-Jie Zhang, Jia-Le Zhao, Hao-Cheng Gu, Han-You Wu, Guo-Si-Lang Zuo, Ke-Yu Deng, Hong-Bo Xi. Bone marrow cells are differentiated into MDSCs by BCC-Ex through down-regulating the expression of CXCR4 and activating STAT3 signalling pathway. Journal of cellular and molecular medicine. vol 25. issue 12. 2021-10-01. PMID:33955151. |
western blot showed that bcc-ex significantly promoted the phosphorylation of stat3 in bone marrow cells, resulting in the inhibitions of the proliferation and apoptosis of bone marrow cells, and the aggravation of the differentiation of bone marrow cells into mdscs. |
2021-10-01 |
2023-08-13 |
mouse |
| Woo-Ju Song, Jang-Hyuk Yun, Myeong-Seon Jeong, Kil-Nam Kim, Taekyun Shin, Hyoung-Chun Kim, Myung-Bok Wi. Inhibitors of Lipoxygenase and Cyclooxygenase-2 Attenuate Trimethyltin-Induced Neurotoxicity through Regulating Oxidative Stress and Pro-Inflammatory Cytokines in Human Neuroblastoma SH-SY5Y Cells. Brain sciences. vol 11. issue 9. 2021-10-01. PMID:34573138. |
apoptosis induced by tmt was identified by altered expression of cleaved caspase-3, bax, bcl-2, and bcl-xl through western blot analysis. |
2021-10-01 |
2023-08-13 |
human |
| Shanshan Chen, Changping Deng, Wenyun Zheng, Shihui Li, Yuping Liu, Tong Zhang, Chen Zhang, Yunhui Fu, Hui Miao, Fuzheng Ren, Xingyuan M. Cannabidiol Effectively Promoted Cell Death in Bladder Cancer and the Improved Intravesical Adhesion Drugs Delivery Strategy Could Be Better Used for Treatment. Pharmaceutics. vol 13. issue 9. 2021-10-01. PMID:34575494. |
qrt-pcr and western blot assays verified that cbd regulated bc cells growth and migration and induced apoptosis by inactivating the pi3k/akt pathway. |
2021-10-01 |
2023-08-13 |
mouse |
| Saima Ali, Muhammad Rashid Khan, Riffat Batool, Sayed Afzal Shah, Javed Iqbal, Banzeer Ahsan Abbasi, Tabassum Yaseen, Nida Zahra, Adil Aldhahrani, Fayez Althobait. Characterization and phytochemical constituents of Periploca hydaspidis Falc crude extract and its anticancer activities. Saudi journal of biological sciences. vol 28. issue 10. 2021-10-01. PMID:34588860. |
the specified cells were studied for migration and invasion potential along with performing western blot analysis of proteins involved in apoptosis, cell-cycle, metastasis, and mapk (mitogen-activated protein kinase) cell-signaling pathway. |
2021-10-01 |
2023-08-13 |
Not clear |
| Hongtao Dong, Menghua Wang, Qiuming L. Exosomal miR-4488 and miR-1273g-5p inhibit the epithelial-mesenchymal transition of transforming growth factor β2-mediated retinal pigment epithelial cells by targeting ATP-binding cassette A4. Bioengineered. 2021-10-01. PMID:34592902. |
the promotion levels of exosomes markers, emt markers, apoptosis markers and abca4 were determined by western blot analysis. |
2021-10-01 |
2023-08-13 |
Not clear |
| Ya-Nan Yang, Hui Zhu, Xiang Yuan, Xu Zhang, Zi-Ming Feng, Jian-Shuang Jiang, Pei-Cheng Zhan. Seven new prenylated flavanones from the roots of Sophora flavescens and their anti-proliferative activities. Bioorganic chemistry. vol 109. 2021-09-30. PMID:33607362. |
western blot experiments demonstrated that 21 could activate the key signaling protein of autophagy and ros, while it does not affect the main protein of the apoptosis signaling pathway. |
2021-09-30 |
2023-08-13 |
human |
| Dijun Ou, Wenbin Ding, Changjun Tong, Weihong Y. Knockdown of Long Non-coding RNA LINC00473 Protects CHON-001 Cells against Interleukin-1β-Induced Cell Injury. Biological & pharmaceutical bulletin. vol 44. issue 2. 2021-09-27. PMID:33268698. |
protein expression, cell apoptosis and cell proliferation of chon-001 cells were investigated by western blot, annexin v and propidium iodide (pi) double staining, cell counting-8 kit assay and immunofluorescence staining respectively. |
2021-09-27 |
2023-08-13 |
human |
| Muhammad Daniyal, Yongbei Liu, Yupei Yang, Feng Xiao, Jialong Fan, Huanghe Yu, Yixing Qiu, Bin Liu, Wei Wang, Qin Yuhu. Anti-gastric cancer activity and mechanism of natural compound "Heilaohulignan C" isolated from Kadsura coccinea. Phytotherapy research : PTR. vol 35. issue 7. 2021-09-27. PMID:34155704. |
western blot analysis confirmed that (b-6) decrease the level of bcl-2 and increase the level of p53, bax, and cleaved caspase-3, this confirms that the b-6 doing the apoptosis through caspase and cytochrome c apoptotic pathways. |
2021-09-27 |
2023-08-13 |
mouse |
| Xiaoqing Bi, Zhenjuan Jiang, Zhaohui Luan, Daoqing Qi. Crocin exerts anti-proliferative and apoptotic effects on cutaneous squamous cell carcinoma via miR-320a/ATG2B. Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34320900. |
the autophagy and apoptosis proteins expressions were further confirmed through western blot and immunofluorescence staining assays. |
2021-09-27 |
2023-08-13 |
mouse |
| Yingying Yu, Guojing Li, Xiaoying He, Yu Lin, Zheng Chen, Xianhua Lin, Hong X. MicroRNA-21 regulate the cell apoptosis and cell proliferation of polycystic ovary syndrome (PCOS) granulosa cells through target toll like receptor TLR8. Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34516355. |
after this rt-pcr, western blot assessment and detection of apoptosis by flow cytometry were conducted. |
2021-09-27 |
2023-08-13 |
cattle |
| Xiaoliang Mei, Hao Din, Jianning Zhao, Jian Tong, Wei Zh. Transcription factor Krüppel-like factor 5-regulated N-myc downstream-regulated gene 2 reduces IL-1β-induced chondrocyte inflammatory injury and extracellular matrix degradation. Bioengineered. vol 12. issue 1. 2021-09-27. PMID:34551684. |
the protein expression related to apoptosis, inflammation or extracellular matrix (ecm) degradation was detected by western blot. |
2021-09-27 |
2023-08-13 |
human |
| Yan Liu, Tingting Bi, Fukang Yuan, Xinbao Gao, Gaolei Jia, Zhilong Tia. S-adenosylmethionine induces apoptosis and cycle arrest of gallbladder carcinoma cells by suppression of JAK2/STAT3 pathways. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 12. 2021-09-24. PMID:32219484. |
cells were dealt with sam and subjected to cell viability, colony formation, hoechst staining, apoptosis, cycle arrest, western blot, and xenograft tumorigenicity assay. |
2021-09-24 |
2023-08-13 |
human |
| Soghra Mehri, Samira Barangi, Ehsan Zamiri, Gholamreza Karim. The protective effect of melatonin on benzo(a)pyrene-induced brain injury: role of apoptosis and autophagy pathways. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 12. 2021-09-24. PMID:32632567. |
western blot was conducted for the level of lc3 ii/i and beclin1, as autophagy markers, caspase3 and bcl2, as apoptosis proteins, and sirt1 in the brain. |
2021-09-24 |
2023-08-13 |
mouse |
| Nina Seiwert, Janine Adam, Pablo Steinberg, Stefan Wirtz, Tanja Schwerdtle, Petra Adams-Quack, Nadine Hövelmeyer, Bernd Kaina, Sebastian Foersch, Jörg Fahre. Chronic intestinal inflammation drives colorectal tumor formation triggered by dietary heme iron in vivo. Archives of toxicology. vol 95. issue 7. 2021-09-24. PMID:33978766. |
dietary heme iron catalyzed formation of fecal n-nitroso compounds and was genotoxic in intestinal epithelial cells, yet suppressed intestinal apoptosis as evidenced by confocal microscopy and western blot analysis. |
2021-09-24 |
2023-08-13 |
mouse |
| Chengcheng Huang, Hui Cao, Jie Qin, Lei Xu, Fang Hu, Yong Gu, Changsheng Dou, Shifa Zhan. Ubiquitin-Specific Protease 14 (USP14) Aggravates Inflammatory Response and Apoptosis of Lung Epithelial Cells in Pneumonia by Modulating Poly (ADP-Ribose) Polymerase-1 (PARP-1). Inflammation. vol 44. issue 5. 2021-09-24. PMID:34085162. |
tunel staining and western blot analysis were adopted to determine cell apoptosis. |
2021-09-24 |
2023-08-13 |
human |
| Hao Chen, Xin Tang, Ting-Li Han, Jia-Nan Zhu, Wei Zhou, Philip N Baker, Chang Chen, Hua Zhan. Potential role of FoxO3a in the regulation of trophoblast development and pregnancy complications. Journal of cellular and molecular medicine. vol 25. issue 9. 2021-09-22. PMID:33811439. |
western blot, immunohistochemistry, cell counting kit-8, wound-healing assay, matrigel invasion assay, cell apoptosis, cell cycle assay, rna sequencing, qrt-pcr and chip-qpcr were performed on the cells to study the potential role of foxo3a and the underlying mechanism. |
2021-09-22 |
2023-08-13 |
Not clear |
| Suoli Cheng, Xueqin Liu, Fan Gong, Xiaoling Ding, Xuebing Zhou, Cuiyun Liu, Fei Zhao, Xiaoliang Li, Jiandang Sh. Dexamethasone promotes the endoplasmic reticulum stress response of bone marrow mesenchymal stem cells by activating the PERK-Nrf2 signaling pathway. Pharmacology research & perspectives. vol 9. issue 3. 2021-09-22. PMID:34038621. |
flow cytometry and western blot assay were performed to detect the effect of dex on the apoptosis of bmscs. |
2021-09-22 |
2023-08-13 |
Not clear |
| Qian Zhou, Ling Zhan. MicroRNA-183-5p protects human derived cell line SH-SY5Y cells from mepivacaine-induced injury. Bioengineered. vol 12. issue 1. 2021-09-22. PMID:34180760. |
we employed western blot for detecting pdcd4 protein levels, as well as flow cytometry and hoechst 33342/pi double staining for determining cell apoptosis rate. |
2021-09-22 |
2023-08-13 |
human |