| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Farzaneh-Sadat Rezazadeh-Shojaee, Elham Ramazani, Jamal Kasaian, Zahra Tayarani-Najara. Protective effects of 6-gingerol on 6-hydroxydopamine-induced apoptosis in PC12 cells through modulation of SAPK/JNK and survivin activation. Journal of biochemical and molecular toxicology. 2021-11-16. PMID:34783140. |
cell viability, cell apoptosis, and stress-activated protein kinase/c-jun n-terminal kinase (sapk/jnk), and survivin expression were measured using resazurin, propidium iodide (pi) and flow cytometry, and western blot analysis. |
2021-11-16 |
2023-08-13 |
Not clear |
| Peipei Ge, Mingxiao Gao, Juan Du, Jingbin Yu, Lei Zhan. Downregulation of microRNA-512-3p enhances the viability and suppresses the apoptosis of vascular endothelial cells, alleviates autophagy and endoplasmic reticulum stress as well as represses atherosclerotic lesions in atherosclerosis by adjusting spliced/unspliced ratio of X-box binding protein 1 (XBP-1S/XBP-1U). Bioengineered. 2021-11-16. PMID:34783632. |
proliferation, apoptosis and migration of huvecs were evaluated by performing cck-8, tunel staining, western blot and transwell assays. |
2021-11-16 |
2023-08-13 |
mouse |
| Peng An, Jianxiao Xing, Aihong Peng, Xincheng Zhao, Wenjuan Chang, Nannan Liang, Yue Cao, Juan Li, Junqin Li, Ruixia Hou, Xinhua Li, Kaiming Zhan. The regulation of dermal mesenchymal stem cells on keratinocytes apoptosis. Cell and tissue banking. vol 22. issue 1. 2021-11-15. PMID:32990869. |
in this study, we isolated dmscs from normal skin and co-cultured with keratinocytes, and then detected apoptosis of keratinocytes by flow cytometry and expression of apoptosis associated proteins by western blot. |
2021-11-15 |
2023-08-13 |
Not clear |
| Xiao Wang, Tianzuo L. Ropivacaine inhibits the proliferation and migration of colorectal cancer cells through ITGB1. Bioengineered. vol 12. issue 1. 2021-11-15. PMID:33345684. |
dapi staining, annexin v staining and western blot were used to detect the expression of apoptosis-related proteins to investigate the effect of ropivacaine on cell apoptosis. |
2021-11-15 |
2023-08-13 |
Not clear |
| Derong Yin, Xiaohong L. Silencing of long non-coding RNA HCP5 inhibits proliferation, invasion, migration, and promotes apoptosis via regulation of miR-299-3p/SMAD5 axis in gastric cancer cells. Bioengineered. vol 12. issue 1. 2021-11-15. PMID:33371778. |
the expressions of proteins associated with apoptosis and invasion were detected by western blot. |
2021-11-15 |
2023-08-13 |
Not clear |
| Tahereh Kashkoulinejad-Kouhi, Shahrokh Safarian, Blanca Arnaiz, Laura Sa. Enhancement of cisplatin sensitivity in human breast cancer MCF-7 cell line through BiP and 14-3-3ζ co-knockdown. Oncology reports. vol 45. issue 2. 2021-11-15. PMID:33416155. |
apoptosis assays were performed using flow cytometry, tunel assays utilized confocal microscopy followed by western blot analysis and caspase-3 and jnk activities were investigated to assess the outcomes. |
2021-11-15 |
2023-08-13 |
human |
| Qi Zhang, Tao Xue, Jianming Guan, Wei Wang, Ji Shi, Jianzhong Lu, Xiping Jian. Irigenin alleviates angiotensin II-induced oxidative stress and apoptosis in HUVEC cells by activating Nrf2 pathway. Drug development research. vol 82. issue 7. 2021-11-15. PMID:33634899. |
after human umbilical vein endothelial cell lines (huvecs) were treated with ang ii (100, 200, 300 and 400 nmol/l) alone, ir (2.5, 5, 10, 20 and 40 μmol/l) alone or ang ii plus ir for 24 h, huvecs viability, lactate dehydrogenase (ldh), apoptosis, oxidative stress, apoptosis-related protein and nuclear factor e2-related factor 2 (nrf2) levels were detected by cell counting kit (cck)-8 assay, enzyme-linked immunosorbent assay, flow cytometry and western blot. |
2021-11-15 |
2023-08-13 |
human |
| Yu Wei Xing, Kuan Zhi Li. Azithromycin inhibited oxidative stress and apoptosis of high glucose-induced podocytes by inhibiting STAT1 pathway. Drug development research. vol 82. issue 7. 2021-11-15. PMID:33655586. |
apoptosis was detected by flow cytometry and apoptosis-related proteins bcl-2, bax, caspase-3, 6, 9, and cleaved caspase-3, 6, 9 were detected by western blot. |
2021-11-15 |
2023-08-13 |
Not clear |
| Muhammad Raisul Abedin, Kaitlyne Powers, Rachel Aiardo, Dibbya Barua, Sutapa Baru. Antibody-drug nanoparticle induces synergistic treatment efficacies in HER2 positive breast cancer cells. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33795712. |
a similar percentage of g2/m arrested cells was found to induce caspase-dependent apoptosis in ptxnr-ttz treated bt-474 cells as revealed using western blot analysis. |
2021-11-15 |
2023-08-13 |
human |
| Kaiqiang Sun, Jian Zhu, Jingchuan Sun, Xiaofei Sun, Le Huan, Bin Zhang, Feng Lin, Bing Zheng, Jialin Jiang, Xi Luo, Ximing Xu, Jiangang Sh. Neuropeptide Y prevents nucleus pulposus cells from cell apoptosis and IL‑1β‑induced extracellular matrix degradation. Cell cycle (Georgetown, Tex.). vol 20. issue 10. 2021-11-15. PMID:33966606. |
cell apoptosis was investigated by hoechst staining, jc-1 staining, annexin v-fitc/pi double staining, and western blot. |
2021-11-15 |
2023-08-13 |
human |
| Liu Xiaoyu, Zhang Wei, Zhao Ming, Jia Guowe. Anti-apoptotic Effect of MiR-223-3p Suppressing PIK3C2A in Cardiomyocytes from Myocardial Infarction Rat Through Regulating PI3K/Akt Signaling Pathway. Cardiovascular toxicology. vol 21. issue 8. 2021-11-15. PMID:33999393. |
four weeks after transfection, the expression levels of mir-223-3p and pik3c2a in tissues as well as pi3k, akt, bax, and bcl-2 mrna in cells were detected by qrt-pcr and western blot, in combination with the detection of apoptosis rate by flow cytometry. |
2021-11-15 |
2023-08-13 |
rat |
| Ziyang Ye, Xinmiao Zhang, Qianli Huang, Wenqing Zhang, Ming Y. Synergistic hepatoprotective effect of combined administration of Lachnum polysaccharide with silymarin. Bioorganic & medicinal chemistry letters. vol 46. 2021-11-15. PMID:34077772. |
tunel staining, immunohistochemical staining and western blot assays demonstrated that the hepatoprotective effect of ch treatment was probably related with inhibiting hepatocyte apoptosis. |
2021-11-15 |
2023-08-13 |
cat |
| Haiyun Huang, Yu Ren, Hongyu Liang, Xiaojia Liu, Jisangmo Nan, Hui Zhao, Xiaoling Li. Mechanism of TCONS_00147848 regulating apoptosis of nasal mucosa cells and alleviating allergic rhinitis through FOSL2-mediated JAK/STAT3 signaling pathway. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:34362948. |
and in this study, we used hematoxylin-eosin (he) staining and terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) to detect the histological changes of nasal mucosa and apoptosis of nasal mucosa epithelial cells in mice, cell counting kit-8 (cck-8) assay, transwell and annexin v/pi to detect proliferation, migration and apoptosis of nasal mucosa cells of mice, respectively, enzyme-linked immunosorbent assay (elisa) to detect the expression of inflammatory factors, qrt-pcr to detect tcons_00147848 expression, western blot assay to detect the expressions of fosl2, jak-2, stat3, p-stat3, bax and bcl-2, rna-binding protein immunoprecipitation (rip) assay, rna pull down assay and co-immunoprecipitation (coip) assay to identify tcons_00147848 targeting fosl2. |
2021-11-15 |
2023-08-13 |
mouse |
| Xia Xu, Jiamiao Ya. β-Caryophyllene may attenuate hyperoxaluria-induced kidney dysfunction in rats by regulating stress marker KIM-1/MCP-1 and NF-κB signaling pathway. Journal of biochemical and molecular toxicology. vol 35. issue 11. 2021-11-15. PMID:34468068. |
furthermore, the results of western blot suggested that bcp may possess inhibitory action on apoptosis by affecting the mitochondrial-dependent apoptotic pathway. |
2021-11-15 |
2023-08-13 |
rat |
| Guo-Wei Qin, Pan Lu, Li Peng, Wei Jian. Ginsenoside Rb1 Inhibits Cardiomyocyte Autophagy via PI3K/Akt/mTOR Signaling Pathway and Reduces Myocardial Ischemia/Reperfusion Injury. The American journal of Chinese medicine. 2021-11-15. PMID:34775933. |
apoptosis, autophagy and pi3k/akt/mtor pathway-related proteins were estimated via western blot. |
2021-11-15 |
2023-08-13 |
rat |
| Liuqing Yang, Lina Li, Pan Chang, Ming Wei, Jianting Chen, Chaofan Zhu, Jing Ji. miR-25 Regulates Gastric Cancer Cell Growth and Apoptosis by Targeting EGR2. Frontiers in genetics. vol 12. 2021-11-13. PMID:34764975. |
functionally, we used rt-qpcr, western blot, cck-8, and flow cytometry to detect gastric cancer cell growth and apoptosis. |
2021-11-13 |
2023-08-13 |
human |
| Qian Li, Ying Tan, Sainan Chen, Xiaochan Xiao, Mingming Zhang, Qi Wu, Maolong Don. Irisin alleviates LPS-induced liver injury and inflammation through inhibition of NLRP3 inflammasome and NF-κB signaling. Journal of receptor and signal transduction research. vol 41. issue 3. 2021-11-12. PMID:32814473. |
pyroptosis, apoptosis, and reactive oxygen species (ros) were evaluated using pi staining, tunel staining, dcfh-da fluorescence, and western blot, respectively. |
2021-11-12 |
2023-08-13 |
Not clear |
| Chen Chen, Lina Lu, Jie Zhu, Xiaoyu Gu, Bofei Liu, Di Li, Gang Che. Miro1 provides neuroprotection via the mitochondrial trafficking pathway in a rat model of traumatic brain injury. Brain research. vol 1773. 2021-11-12. PMID:34637761. |
real-time polymerase chain reaction, western blot, immunofluorescence, adenosine triphosphate (atp) level assay, neuronal apoptosis, brain water content measurement, and neurological score analyses were carried out. |
2021-11-12 |
2023-08-13 |
rat |
| Shuo Cong, Yongmei Liu, Yi Li, Yu Chen, Rui Chen, Baofang Zhang, Lei Yu, Yaxin Hu, Xueke Zhao, Mao Mu, Mingliang Cheng, Zhi Huan. MiR-571 affects the development and progression of liver fibrosis by regulating the Notch3 pathway. Scientific reports. vol 11. issue 1. 2021-11-12. PMID:34750395. |
cck-8, cell scratch assays, transwell assays, flow cytometry were used to determine the effect of mir-571 on lx-2 proliferation, migration, apoptosis in human stem stellate cells, and rt-pcr, western blot assays were performed to determine the effect of mir-571 on the notch3 signaling pathway and the expression of profibrogenic factors. |
2021-11-12 |
2023-08-13 |
human |
| Houfeng Huang, Xinrong Fan, Yi Qiao, Ming Yang, Zhigang J. Knockdown of KNTC1 Inhibits the Proliferation, Migration and Tumorigenesis of Human Bladder Cancer Cells and Induces Apoptosis. Critical reviews in eukaryotic gene expression. vol 31. issue 1. 2021-11-11. PMID:33639055. |
human apoptosis antibody array and western blot were used to detect the expression level changes of related proteins after kntc1 knockdown to explore the possible mechanism. |
2021-11-11 |
2023-08-13 |
human |