| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiong Wu, Hong Yang, Ruiqing Tai, Chaowei Li, Tianyu Xia, Yongnian Liu, Chao Su. Lnc-hipk1 inhibits mouse adipocyte apoptosis as a sponge of miR-497. BioFactors (Oxford, England). 2021-12-02. PMID:34856026. |
the role of mir-497 in the apoptosis and proliferation of mouse-derived adipocytes was detected by rna-seq analysis, rt-qpcr, western blot, immunofluorescence, and dual-luciferase reporter assay. |
2021-12-02 |
2023-08-13 |
mouse |
| Zhirong He, Yanyan Zhao, Yongxia Zhu, Weihua Wang, Xin Liu, Fen L. Interfering TUG1 Attenuates Cerebrovascular Endothelial Apoptosis and Inflammatory injury After Cerebral Ischemia/Reperfusion via TUG1/miR-410/FOXO3 ceRNA Axis. Neurotoxicity research. 2021-12-01. PMID:34851489. |
neural function, apoptosis, and inflammatory damage were assessed by triphenyltetrazolium chloride straining, modified neurological severity score, fluorescence-activated cell sorting method, and western blot. |
2021-12-01 |
2023-08-13 |
mouse |
| Rohit Shetty, Nimisha Rajiv Kumar, Murali Subramani, Lekshmi Krishna, Ponnalagu Murugeswari, Himanshu Matalia, Pooja Khamar, Zelda V Dadachanji, Rajiv R Mohan, Arkasubhra Ghosh, Debashish Da. Safety and efficacy of combination of suberoylamilide hydroxyamic acid and mitomycin C in reducing pro-fibrotic changes in human corneal epithelial cells. Scientific reports. vol 11. issue 1. 2021-11-30. PMID:33623133. |
the cells/tissue was then analyzed by rt-qpcr, immunofluorescence and western blot for markers of apoptosis and fibrosis. |
2021-11-30 |
2023-08-13 |
human |
| Beige Zong, Lu Sun, Yang Peng, Yihua Wang, Yu Yu, Jinwei Lei, Yingzi Zhang, Shipeng Guo, Kang Li, Shengchun Li. HORMAD1 promotes docetaxel resistance in triple negative breast cancer by enhancing DNA damage tolerance. Oncology reports. vol 46. issue 1. 2021-11-30. PMID:34036395. |
the levels of key apoptosis regulators and autophagy markers were detected by western blot analysis. |
2021-11-30 |
2023-08-13 |
human |
| Yuchen Sun, Liangzhao Chu, Huijuan Wang, Han Peng, Jian Li. Inhibitory effect of gefitinib derivative LPY‑9 on human glioma. Molecular medicine reports. vol 24. issue 3. 2021-11-30. PMID:34212976. |
the present study aimed to investigate the effects of a gefitinib derivative, lpy‑9, on the proliferation, apoptosis and migration of human glioma cell line u251‑mg by cck8, transwell or flow cytometry, and the effect of lpy‑9 on the activity of caspase‑3 enzyme and related proteins in the vascular endothelial growth factor (vegf) and epidermal growth factor receptor (egfr) pathways by western blot and elisa. |
2021-11-30 |
2023-08-13 |
human |
| Baskaran Stephen Inbaraj, Leng-Huei Hua, Bing-Huei Che. Comparative Study on Inhibition of Pancreatic Cancer Cells by Resveratrol Gold Nanoparticles and a Resveratrol Nanoemulsion Prepared from Grape Skin. Pharmaceutics. vol 13. issue 11. 2021-11-30. PMID:34834286. |
western blot analysis implied that both can down-regulate expressions of cyclin a, cyclin b, cdk1, and cdk2 and up-regulate expressions of p53 and p21, accompanied by enhancing cytochrome c expression, decreasing bcl-2 expression, increasing bax expression, and leading to the elevation of caspase-8, caspase-9, and caspase-3 activities for cell apoptosis execution. |
2021-11-30 |
2023-08-13 |
Not clear |
| Qiang Zhou, Jianxia Yuan, Yi Liu, Yayun W. Cisatracurium besilate enhances the TRAIL-induced apoptosis of gastric cancer cells via p53 signaling. Bioengineered. vol 12. issue 2. 2021-11-30. PMID:34845969. |
the ags cell line was exposed to cisatracurium besilate, and then cell viability, colony formation and apoptosis were assessed by performing cell counting kit-8, colony formation, tunel and western blot assays, respectively. |
2021-11-30 |
2023-08-13 |
Not clear |
| Hang Yin, Hao Qin, Tiantian Wang, Qiang Zhuang, Qixia Yan. The Protective Effects of Apremilast Against Oxygen-Glucose Deprivation/Reperfusion (OGD/R)-Induced Inflammation and Apoptosis in Astroglia Mediated by CREB/BDNF. Neurotoxicity research. vol 39. issue 3. 2021-11-29. PMID:33826130. |
in the present study, we employed an in vitro model of ischemic stroke using oxygen-glucose deprivation and reoxygenation (ogd/r)-challenged astrocytes to investigate the effects of apremilast against apoptosis (the flow cytometry assay), cell death (the lactate dehydrogenase release assay), oxidative stress (2', 7' dichlorofluorescin diacetate staining), and the expression of the key neuroprotective factors creb and bdnf (western blot analysis). |
2021-11-29 |
2023-08-13 |
Not clear |
| Huiying Pan, Yi Xu, Qian Cai, Meiling Wu, Mingxing Din. Effects of β-Asarone on Ischemic Stroke in Middle Cerebral Artery Occlusion Rats by an Nrf2-Antioxidant Response Elements (ARE) Pathway-Dependent Mechanism. Medical science monitor : international medical journal of experimental and clinical research. vol 27. 2021-11-29. PMID:34083500. |
tunel staining and western blot analysis for apoptosis-related proteins were performed to assess the apoptosis of neurons. |
2021-11-29 |
2023-08-13 |
rat |
| Xin-Hui Wang, Rui Lang, Qin Zeng, Ying Liang, Nan Chen, Zhi-Zhong Ma, Ren-Huan Y. Jianpi Qushi Heluo Formula alleviates renal damages in Passive Hemann nephritis in rats by upregulating Parkin-mediated mitochondrial autophagy. Scientific reports. vol 11. issue 1. 2021-11-26. PMID:34526554. |
western blot analysis demonstrated that jqhf could protect against mitochondrial dysfunction and apoptosis by upregulating the expression of pink1, mitochondrial parkin, and lc3-ii/i, downregulating the expression of cytoplasmic parkin, p62, cytochrome c, and caspase-3 in the kidneys of mn rats. |
2021-11-26 |
2023-08-13 |
rat |
| Feixiang Chen, Jiadong Zhu, Wei Wan. Ulinastatin Attenuates LPS-Induced Inflammation and Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis in Renal Tubular Epithelial Cells via Regulation of the TLR4/NF-κB and Nrf2/HO-1 Pathways. Inflammation. vol 44. issue 6. 2021-11-26. PMID:34585338. |
the apoptosis and inflammation of hk-2 cells were then determined by tunel, western blot, elisa, and rt-qpcr. |
2021-11-26 |
2023-08-13 |
Not clear |
| L Zhou, S Li, J Su. Ginkgolic acid induces apoptosis and autophagy of endometrial carcinoma cells via inhibiting PI3K/Akt/mTOR pathway in vivo and in vitro. Human & experimental toxicology. vol 40. issue 12. 2021-11-25. PMID:34132136. |
flow cytometry assay and western blot assay were applied to examine the apoptosis and apoptosis related protein bcl-2, bax, cleaved caspase-3 expression levels of ishikawa and hec-1-b cells after treatment with ga. next, we applied western blot assay to analyze the autophagy associated proteins lc3i, lc3ii, p62 and beclin-1 in ga treated ishikawa and hec-1-b cells. |
2021-11-25 |
2023-08-13 |
Not clear |
| Qin Yang, Zhiyi Fei, Chunyan Huan. Betulin terpenoid targets OVCAR-3 human ovarian carcinoma cells by inducing mitochondrial mediated apoptosis, G2/M phase cell cycle arrest, inhibition of cell migration and invasion and modulating mTOR/PI3K/AKT signalling pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 67. issue 2. 2021-11-25. PMID:34817343. |
effects on cell apoptosis were studied by fluorescence microscopy and western blot. |
2021-11-25 |
2023-08-13 |
human |
| Yan Wang, Quande Lin, Chunge Song, Ruojin Ma, Xiaojie L. Depletion of circ_0007841 inhibits multiple myeloma development and BTZ resistance via miR-129-5p/JAG1 axis. Cell cycle (Georgetown, Tex.). vol 19. issue 23. 2021-11-24. PMID:33131409. |
moreover, cell apoptosis was assessed by flow cytometry and western blot analysis. |
2021-11-24 |
2023-08-13 |
Not clear |
| Huaxia Chen, Xiao Xu, Linying Lai, Ran Huo, Minliang Che. Circ_0008450 downregulates Runx3 to promote the proliferation and epithelial-mesenchymal transition of human keratinized epithelial cells. Cell cycle (Georgetown, Tex.). vol 19. issue 23. 2021-11-24. PMID:33131417. |
when primary human keratinized epithelial cells were transfected by sh-circ_0008450 or sh-runx3, cell proliferation, apoptosis, migration, and emt process were assessed by cck-8, brdu assay, apoptosis assay, migration assay, and western blot. |
2021-11-24 |
2023-08-13 |
human |
| Chunling Shi, Min Weng, Hengyue Zhu, Yangyang Guo, Dongdong Xu, Hairu Jin, Binshuang Wei, Zhensheng Ca. NUDCD1 knockdown inhibits the proliferation, migration, and invasion of pancreatic cancer via the EMT process. Aging. vol 13. issue 14. 2021-11-23. PMID:34325402. |
western blot was conducted to assess the expression of markers associated with apoptosis and epithelial-mesenchymal transition (emt). |
2021-11-23 |
2023-08-13 |
human |
| Xiaolin Lu, Liling Chen, Yang Li, Rong Huang, Xiangfeng Meng, Fangfang Su. Long non-coding RNA LINC01207 promotes cell proliferation and migration but suppresses apoptosis and autophagy in oral squamous cell carcinoma by the microRNA-1301-3p/lactate dehydrogenase isoform A axis. Bioengineered. vol 12. issue 1. 2021-11-23. PMID:34463208. |
cell viability, proliferation, migration, apoptosis, and autophagy were detected using cell counting kit-8 (cck-8), colony formation, transwell assays, flow cytometry, and western blot analysis. |
2021-11-23 |
2023-08-13 |
Not clear |
| Sezer Akgol, Batuhan Mert Kalkan, Dogacan Yucel, Fatih Kocaba. SC1 limits tube formation, branching, migration, expansion and induce apoptosis of endothelial cells. Vascular pharmacology. vol 141. 2021-11-23. PMID:34481979. |
to this end, we performed viability, apoptosis, cell cycle, gene expression, wound closure, tube formation, and western blot analysis in endothelial cells post sc1 treatments. |
2021-11-23 |
2023-08-13 |
Not clear |
| Zongwei Li, Jianming Wang, Yumin M. Montelukast attenuates interleukin IL-1β-induced oxidative stress and apoptosis in chondrocytes by inhibiting CYSLTR1 (Cysteinyl Leukotriene Receptor 1) and activating KLF2 (Kruppel Like Factor 2). Bioengineered. vol 12. issue 1. 2021-11-23. PMID:34565285. |
cell apoptosis and cartilage degradation were examined by tdt-mediated dutp nick-end labeling (tunel) assay, western blot and rt-qpcr. |
2021-11-23 |
2023-08-13 |
Not clear |
| Jiajie Feng, Jiachen Zhan, Shuangshuang M. LRG1 promotes hypoxia-induced cardiomyocyte apoptosis and autophagy by regulating hypoxia-inducible factor-1α. Bioengineered. vol 12. issue 1. 2021-11-23. PMID:34643170. |
in this study, western blot was applied to detect the protein expression of bax, bcl2, lc3, p62, lrg1 and hypoxia-inducible factor-1α (hif-1α); cck-8 assay was employed to detect cell viability; annexin v-fitc/pi staining was adopted to evaluate apoptosis, and immunofluorescence assay was applied to detect autophagy. |
2021-11-23 |
2023-08-13 |
Not clear |