| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yujiao Yang, Junke Song, NanNan Liu, Guangyi Wei, Shan Liu, Sen Zhang, Nan Jiang, Haiguang Yang, Guanhua D. Salvianolic acid A relieves cognitive disorder after chronic cerebral ischemia: Involvement of Drd2/Cryab/NF-κB pathway. Pharmacological research. vol 175. 2021-12-11. PMID:34800628. |
tunel staining, enzyme-linked immunosorbent assay, and western blot analysis were used to detect the inflammatory and apoptosis in the cortex and hippocampus. |
2021-12-11 |
2023-08-13 |
rat |
| Hongwu Meng, Ruowen Niu, Hongmei You, Ling Wang, Rui Feng, Cheng Huang, Jun L. Interleukin-9 attenuates inflammatory response and hepatocyte apoptosis in alcoholic liver injury. Life sciences. vol 288. 2021-12-11. PMID:34843736. |
moreover, flow cytometry and western blot results displayed that macrophage-derived il-9 inhibited hepatocyte apoptosis. |
2021-12-11 |
2023-08-13 |
mouse |
| Jiang Han, Cui-Xia Pu, Qiu-Xia Xiao, Li-Jia Tang, Ting Liu, Li He, Ying-Bo Ren, Qing Liu, Ying Zhan. miRNA-124-3p targeting of LPIN1 attenuates inflammation and apoptosis in aged male rats cardiopulmonary bypass model of perioperative neurocognitive disorders. Experimental gerontology. vol 155. 2021-12-10. PMID:34601076. |
moreover, the results of ihc, elisa, western blot analysis (wb) and terminal-deoxynucleotidyl transferase mediated nick end labeling assay (tunel) showed cpb procedure induced inflammation and apoptosis in rats with pnd. |
2021-12-10 |
2023-08-13 |
rat |
| Zhongyan Zhao, Chanji Wu, Xiangying He, Eryi Zhao, Shijun Hu, Yeguang Han, Ting Wang, Yanquan Chen, Tao Liu, Shixiong Huan. MicroRNA let-7f alleviates vascular endothelial cell dysfunction via targeting HMGA2 under oxygen-glucose deprivation and reoxygenation. Brain research. vol 1772. 2021-12-09. PMID:34529965. |
cck-8 assays, flow cytometry and western blot analyses were conducted to examine the viability and apoptosis of bend.3 cells. |
2021-12-09 |
2023-08-13 |
Not clear |
| Zhongyan Zhao, Chanji Wu, Xiangying He, Eryi Zhao, Shijun Hu, Yeguang Han, Ting Wang, Yanquan Chen, Tao Liu, Shixiong Huan. MicroRNA let-7f alleviates vascular endothelial cell dysfunction via targeting HMGA2 under oxygen-glucose deprivation and reoxygenation. Brain research. vol 1772. 2021-12-09. PMID:34529965. |
endothelial cell permeability in vitro assay was employed to assess endothelial permeability of bend.3 cells, and expression levels of proteins associated with cell apoptosis or blood-brain barrier (bbb) were detected by western blot analyses. |
2021-12-09 |
2023-08-13 |
Not clear |
| Gamze Guney Eskiler, Asuman Deveci Ozkan, Ayten Haciefendi, Cemil Bili. Mechanisms of abemaciclib, a CDK4/6 inhibitor, induced apoptotic cell death in prostate cancer cells in vitro. Translational oncology. vol 15. issue 1. 2021-12-09. PMID:34649150. |
in this study, in vitro cytotoxic and apoptotic effects of abe on metastatic castration-resistant prostate cancer (mcrpc) androgen receptor (ar) negative pc-3 and ar mutant lncap pc cells were analyzed with wst-1, annexin v, cell cycle, reactive oxygen species (ros), mitochondrial membrane potential, rt-pcr, western blot, and apoptosis protein array. |
2021-12-09 |
2023-08-13 |
Not clear |
| Shan-Shan Liu, Jin-Qing Hu, Jin-Fa Gu, Ai-Min Ni, Wen-Hao Tang, Xin-Yuan Li. Combined oncolytic adenovirus carrying MnSOD and mK5 genes both regulated by survivin promoter has a synergistic inhibitory effect on gastric cancer. Neoplasma. 2021-12-09. PMID:34881625. |
cell staining, flow cytometry, and western blot analysis showed that the combination of two adenoviruses containing therapeutic genes could promote the apoptosis of cancer cells. |
2021-12-09 |
2023-08-13 |
mouse |
| Wiwat Chancharoenthana, Kanyarat Udompronpitak, Yolradee Manochantr, Piyawat Kantagowit, Ponthakorn Kaewkanha, Jiraporn Issara-Amphorn, Asada Leelahavanichku. Repurposing of High-Dose Erythropoietin as a Potential Drug Attenuates Sepsis in Preconditioning Renal Injury. Cells. vol 10. issue 11. 2021-12-08. PMID:34831360. |
as such, increased endogenous epo was demonstrated in all sepsis models, including binx-clp despite the reduced liver erythropoietin receptor (epor), using western blot analysis and gene expression, in liver (partly through hepatocyte apoptosis). |
2021-12-08 |
2023-08-13 |
mouse |
| Yan Qian, Xin Li, Raofei Fan, Qiaofen Li, Yang Zhang, Xiaona He, Wei Yang, Wei Sun, Shaokun L. MicroRNA-31 inhibits traumatic brain injury-triggered neuronal cell apoptosis by regulating hypoxia-inducible factor-1A/vascular endothelial growth factor A axis. Neuroreport. vol 33. issue 1. 2021-12-08. PMID:34874324. |
cell counting kit-8, lactate dehydrogenase assay, terminal deoxynucleotidyl transferase-mediated dutp nick-end labeling, and western blot were applied to examine cell viability, lactate dehydrogenase releasing, apoptosis, and apoptosis-related protein. |
2021-12-08 |
2023-08-13 |
Not clear |
| Jinxiang Yu, Qianyun Zhang, Jie Li, Zhaohui Si, Yuanyuan Guo, Xin Xu, Kanjin W. Sequential administration of pemetrexed and cisplatin reprograms tumor immune microenvironment and potentiates PD-1/PD-L1 treatment in a lung cancer model. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 2021-12-07. PMID:34872935. |
western blot, qrt-pcr, and immunohistochemical staining were applied to detect the expression of apoptosis, cell cycle, and stimulator of interferon genes (sting) pathway-related markers. |
2021-12-07 |
2023-08-13 |
mouse |
| Jia Chen, Mingyang Wang, Hanli Wang, Miao Lon. Zearalenone promotes apoptosis of mouse Leydig cells by targeting phosphatase and tensin homolog and thus inhibiting the PI3K/AKT signal pathway. Environmental science and pollution research international. vol 28. issue 47. 2021-12-06. PMID:34264493. |
apoptosis was detected cytometrically and the protein expression levels of pten, akt, p-akt, bax, and bcl-2 were evaluated via western blot analysis. |
2021-12-06 |
2023-08-13 |
mouse |
| Yuzhu Di, Yanan Jiang, Xiuyun Shen, Jing Liu, Yang Gao, Huimin Cai, Xiaoli Sun, Dandan Ning, Bing Liu, Jiaji Lei, Shizhu Ji. Downregulation of miR-135b-5p Suppresses Progression of Esophageal Cancer and Contributes to the Effect of Cisplatin. Frontiers in oncology. vol 11. 2021-12-06. PMID:34277424. |
cck8, edu, wound healing, transwell assay, and western blot demonstrated mir-135b-5p inhibition suppresses proliferation, invasion, migration and promoted the apoptosis in eca109 and ec9706 cells. |
2021-12-06 |
2023-08-13 |
human |
| Shui Lian Chou, Samiraj Ramesh, Chia-Hua Kuo, Ayaz Ali, Tsung-Jung Ho, Ko Peng Chang, Dennis Jine-Yuan Hsieh, V Bharath Kumar, Yueh-Shan Weng, Wei-Wen Kuo, Chih-Yang Huan. Tanshinone IIA inhibits Leu27IGF-II-induced insulin-like growth factor receptor II signaling and myocardial apoptosis via estrogen receptor-mediated Akt activation. Environmental toxicology. vol 37. issue 1. 2021-12-06. PMID:34655285. |
however, the western blot analysis, jc-1 staining, and terminal deoxynucleotide transferase-mediated dutp nick end labeling assay revealed that tsn iia attenuated leu27igf-ii-induced igf-iir mediated cardiac apoptosis was reversed by an er antagonist such as ici 182780, and pi3k inhibition. |
2021-12-06 |
2023-08-13 |
Not clear |
| Zhen Zhan. Silencing LINC00504 inhibits cell proliferation, invasion as well as migration and promotes cell apoptosis in lung cancer cells via upregulating miR-876-3p. Cytotechnology. 2021-12-03. PMID:33033968. |
the apoptosis related protein expressions were measured by western blot. |
2021-12-03 |
2023-08-13 |
Not clear |
| Dazhi Fu, Qiang Ji, Chunxiao Wang, Lei Yu, Rui Y. Aloin decelerates the progression of hepatocellular carcinoma through circ_0011385/miR-149-5p/WT1 axis. Cell cycle (Georgetown, Tex.). vol 20. issue 23. 2021-12-03. PMID:34720052. |
cell viability, invasion, apoptosis and autophagy were accessed by cell counting kit-8 (cck-8), transwell invasion assay, flow cytometry, western blot and immunofluorescence analysis, respectively. |
2021-12-03 |
2023-08-13 |
mouse |
| Cuihui Wang, Hongying Zhang, Ji L. LncRNA JHDM1D-AS1 Suppresses MPP + -Induced Neuronal Injury in Parkinson's Disease via miR-134-5p/PIK3R3 Axis. Neurotoxicity research. vol 39. issue 6. 2021-12-03. PMID:34773593. |
cell viability and apoptosis were determined using cck-8 assay, flow cytometry, and western blot, respectively. |
2021-12-03 |
2023-08-13 |
Not clear |
| Wei Li, Yanqiu Zhang, Jifeng Xu, Jincan Chen, Xia Ga. Fasudil prevents neomycin-induced hair cell damage by inhibiting autophagy through the miR-489/NDP52 signaling pathway in HEI-OC1 cells. Experimental and therapeutic medicine. vol 23. issue 1. 2021-12-03. PMID:34849158. |
flow cytometry and western blot analysis were used to detect the effects of fas on cell apoptosis and to determine the expression levels of autophagy-related proteins, lc3b and beclin 1, induced by neo. |
2021-12-03 |
2023-08-13 |
Not clear |
| Qinqin Zhang, Aozi Feng, Mengnan Zeng, Beibei Zhang, Jingya Shi, Yaxin Lv, Bing Cao, Chenxin Zhao, Mengya Wang, Yifan Ding, Xiaoke Zhen. Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways. Innate immunity. vol 27. issue 7-8. 2021-12-02. PMID:34806444. |
the levels of proteins in apoptosis and the tlr4-mapks/nf-κb signaling pathways were detected by western blot. |
2021-12-02 |
2023-08-13 |
mouse |
| Kai Wang, Zhongming Li, Yan Sun, Xianling Liu, Wenjie Ma, Yinzhang Ding, Jian Hong, Lijun Qian, Di X. Dapagliflozin Improves Cardiac Function, Remodeling, Myocardial Apoptosis, and Inflammatory Cytokines in Mice with Myocardial Infarction. Journal of cardiovascular translational research. 2021-12-02. PMID:34855147. |
myocardial apoptosis was analyzed by western blot and immunofluorescence. |
2021-12-02 |
2023-08-13 |
mouse |
| Yuyao Shen, Senwei Zhao, Minglei Hu. Long non-coding RNA LINC01194 promotes the inflammatory response and apoptosis of LPS-treated MLE 12 cells through the miR-203a-3p /MIP-2 axis. Canadian journal of physiology and pharmacology. 2021-12-02. PMID:34855515. |
bioinformatics analysis, elisa assay, qrt-pcr analysis, biotinylated rna pull-down assay, apoptosis test, and western blot analysis demonstrated that the linc01194 could act as a mir-203a-3p sponge to activate the inflammatory response in lps-induced ali model through post-transcriptional upregulation of mip-2. |
2021-12-02 |
2023-08-13 |
mouse |