| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li Chen, Wenting Luo, Peijun Ji, Zhujuan Li, Yi Yan, Qin Zho. Effects of BMI1 Gene on Regulating Apoptosis, Invasion, and Migration of HEC-1B Cells Induced by Ionizing Radiation. Journal of healthcare engineering. vol 2022. 2022-03-14. PMID:35281533. |
cell proliferation was detected by cell counting kit-8 (cck-8); cell migration and invasion were detected by transwell test; cell apoptosis was detected by flow cytometry; and the expression of mmp2, mmp7, mmp9, rock1, rhoa, p53, p21, and bax protein was detected by the western blot. |
2022-03-14 |
2023-08-13 |
human |
| Soumya Ranjan Jena, Ganeswar Dalei, Subhraseema Das, Jasmine Nayak, Manoranjan Pradhan, Luna Samant. Harnessing the potential of dialdehyde alginate-xanthan gum hydrogels as niche bioscaffolds for tissue engineering. International journal of biological macromolecules. 2022-03-11. PMID:35276297. |
the western blot analysis of p53 gene indicated no growth arrest or apoptosis in 3t3 cells thus, signifying the non-toxic nature of the scaffolds. |
2022-03-11 |
2023-08-13 |
Not clear |
| Xiaojing Chang, Lei Jia. LncRNA ZFPM2-AS1 drives the progression of nasopharyngeal carcinoma via modulating the downstream miR-3612/DTL signaling. Anti-cancer drugs. 2022-03-11. PMID:35276693. |
cell apoptosis was estimated based on the expression levels of bcl2-associated x and b-cell lymphoma-2 using western blot assay. |
2022-03-11 |
2023-08-13 |
human |
| Luying Lai, Yongwei Wang, Shenghui Peng, Wenjing Guo, Fengxian Li, Shiyuan X. P53 and taurine upregulated gene 1 promotes the repair of the DeoxyriboNucleic Acid damage induced by bupivacaine in murine primary sensory neurons. Bioengineered. vol 13. issue 3. 2022-03-10. PMID:35271399. |
our work treated dorsal root ganglion (drg) cells with bup, detected cell viability through cck-8, apoptosis through tunel assays, deoxyribonucleic acid (dna) damage through γ-h2ax protein and comet assay, including p53 mrna, protein and tug1 expression through q-pcr and western blot, furthermore, cell viability and dna damage were determined after the silencing of p53 and tug1, biological information and tug1 fish combined with p53 protein immunofluorescence (if) was performed to determine the cellular localization of these molecule. |
2022-03-10 |
2023-08-13 |
Not clear |
| Xiaojiao Zheng, Shixuan Hua, Hang Zhao, Zhou Gao, Dong Ce. Overexpression of hepatocyte growth factor protects chronic myeloid leukemia cells from apoptosis induced by etoposide. Oncology letters. vol 23. issue 4. 2022-03-09. PMID:35261636. |
apoptosis in the k562 cell line was determined using flow cytometry and western blot analysis. |
2022-03-09 |
2023-08-13 |
Not clear |
| Dandan Zheng, Yongming Zhou, Yong Liu, Lihai Ma, Lingzhan Men. Molecular Mechanism Investigation on Monomer Kaempferol of the Traditional Medicine Dingqing Tablet in Promoting Apoptosis of Acute Myeloid Leukemia HL-60 Cells. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-03-07. PMID:35251215. |
the combination of kaempferol and akt1 was verified using an immunoprecipitation (ip) experiment and the effects of kaempferol on hl-60 cell apoptosis by western blot (wb) and qpcr. |
2022-03-07 |
2023-08-13 |
Not clear |
| Xin Lu, Jinlong Zhang, Pengfei Xue, Qinyu Wang, Xiangyu Wang, Yuyu Sun, Zhiming Cu. BAG3 protects chondrocytes against lumbar facet joint osteoarthritis by regulating autophagy and apoptosis. Journal of physiology and biochemistry. 2022-03-07. PMID:35253089. |
western blot analysis data showed significant expression of bag3, apoptosis, and autophagy-related proteins in sw1353 cells. |
2022-03-07 |
2023-08-13 |
human |
| b' Ilias Tsochantaridis, Aglaia Pappa, Egemen Dere, Ferda Ar\\xc4\\xb. Zn(II) 5,5-Diethylbarbiturate complex selectively induces apoptosis in breast cancer and breast cancer stem-like cells. Chemistry & biodiversity. 2022-03-07. PMID:35254725.' |
intrinsic apoptosis pathway in mcf-7 cells and extrinsic apoptosis pathway in mda-mb-231 cells was determined by western blot (parp, cleave parp, bax, cox4, rip, caspase 8, split caspase 8, dr4 and b-actin) and rt-pcr (parp, fas, bcl-2, tnf10a, p53) analysis. |
2022-03-07 |
2023-08-13 |
human |
| Jinfeng Du, Qian Xu, Han Zhao, Xiyun Jia, Nan Ba, Fanghui Peng, Zisen Zhan. PI3K inhibitor 3-MA promotes the antiproliferative activity of esomeprazole in gastric cancer cells by downregulating EGFR via the PI3K/FOXO3a pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 148. 2022-03-01. PMID:35228068. |
cell viability, proliferation, invasion, migration, apoptosis, autophagy, and protein expression were detected by cck-8, edu, transwell, flow cytometry, immunofluorescence assay, and western blot. |
2022-03-01 |
2023-08-13 |
Not clear |
| Shaosheng Liu, Yuanyuan Li, Zhaoxia L. Salidroside suppresses the activation of nasopharyngeal carcinoma cells via targeting miR-4262/GRP78 axis. Cell cycle (Georgetown, Tex.). 2022-02-28. PMID:35220889. |
npc cells were cultured, mtt was used to detect the effect of salidroside on cell proliferation, apoptosis detected by flow cytometry assay, western blot was used to detect the related protein expression. |
2022-02-28 |
2023-08-13 |
mouse |
| Qiurong Sun, Taiyang Zhang, Qingchun Xiao, Bingxin Mei, Xingwang Zhan. Procyanidin B2 inhibits angiogenesis and cell growth in oral squamous cell carcinoma cells through the vascular endothelial growth factor (VEGF)/VEGF receptor 2 (VEGFR2) pathway. Bioengineered. vol 13. issue 3. 2022-02-28. PMID:35220896. |
the protein expression related to apoptosis, metastasis and epithelial-mesenchymal transition (emt) and changed expression of vascular endothelial growth factor (vegf)/vegf receptor 2 (vegfr2) signaling was analyzed by western blot. |
2022-02-28 |
2023-08-13 |
human |
| Yingsi Huang, Suhua Li, Huaxin Chen, Long Feng, Weixiu Yuan, Tao Ha. Butorphanol reduces the neuronal inflammatory response and apoptosis via inhibition of p38/JNK/ATF2/p53 signaling. Experimental and therapeutic medicine. vol 23. issue 3. 2022-02-28. PMID:35222706. |
in addition, the roles of butorphanol and anisomycin in inflammatory factor levels and cell apoptosis were determined using reverse transcription-quantitative pcr, tunel and western blot assays. |
2022-02-28 |
2023-08-13 |
Not clear |
| Xiaodong Weng, Jing Li, Qiunong Guan, Haimei Zhao, Zihuan Wang, Martin E Gleave, Christopher Yc Nguan, Caigan D. The functions of clusterin in renal mesenchymal stromal cells: Promotion of cell growth and regulation of macrophage activation. Experimental cell research. 2022-02-26. PMID:35218723. |
cell surface markers, apoptosis and phagocytosis were determined by flow cytometry, and clu protein by western blot. |
2022-02-26 |
2023-08-13 |
Not clear |
| Lei Zou, Cuifen Shi, Dawei Wang, Juan Cheng, Qi Wang, Lei Wang, Guoya Yan. Long non-coding RNA-non-coding RNA activated by DNA damage inhibition suppresses hepatic stellate cell activation via microRNA-495-3p/sphingosine 1-phosphate receptor 3 axis. Bioengineered. vol 13. issue 3. 2022-02-24. PMID:35200103. |
the effects of pdgf-bb on lx-2 cell viability, migration, invasion, and apoptosis were evaluated using mtt (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide), transwell, flow cytometry, and western blot assays. |
2022-02-24 |
2023-08-13 |
Not clear |
| Wenbo Shao, Cunxin Zhang, Kang Li, Ziang Lu, Zihao Zhao, Kai Gao, Chaoliang L. Wogonin inhibits inflammation and apoptosis through STAT3 signal pathway to promote the recovery of spinal cord injury. Brain research. 2022-02-24. PMID:35202619. |
western blot, tunel staining, and immunofluorescence were used to detect changes in the neuronal inflammation, apoptosis, and stat3 signal pathway. |
2022-02-24 |
2023-08-13 |
rat |
| Wenbo Shao, Cunxin Zhang, Kang Li, Ziang Lu, Zihao Zhao, Kai Gao, Chaoliang L. Wogonin inhibits inflammation and apoptosis through STAT3 signal pathway to promote the recovery of spinal cord injury. Brain research. 2022-02-24. PMID:35202619. |
western blot and immunofluorescence techniques were also performed to detect the regulatory effect and the underlying mechanism of wogonin on the inflammation and apoptosis of pc12 cells. |
2022-02-24 |
2023-08-13 |
rat |
| Xiaoxia Yang, Mengxia Wang, Qian Zhou, Yanxian Bai, Jing Liu, Junhua Yang, Lixia Li, Guoying Li, Li Lu. Macamide B Pretreatment Attenuates Neonatal Hypoxic-Ischemic Brain Damage of Mice Induced Apoptosis and Regulates Autophagy via the PI3K/AKT Signaling Pathway. Molecular neurobiology. 2022-02-22. PMID:35190953. |
ttc staining was performed to evaluate the cerebral infarct volume in pups, the brain water content was measured to evaluate the neurological function of pups, neurobehavioural testing was conducted to assess functional recovery after hibd, tunel and fjc staining was performed to detect cellular autophagy and apoptosis, and western blot analysis was used to detect the levels of proteins in the pro-survival phosphatidylinositol-3-kinase/protein kinase b (pi3k/akt) signaling pathway and autophagy and apoptosis-related proteins. |
2022-02-22 |
2023-08-13 |
mouse |
| Lulu Song, Xingxing Li, Qingwan Sun, Yifeng Zha. Fxyd5 activates the NF‑κB pathway and is involved in chondrocytes inflammation and extracellular matrix degradation. Molecular medicine reports. vol 25. issue 4. 2022-02-22. PMID:35191523. |
the protein expression levels of fxyd5, mmps and proteins related to ecm, apoptosis and nf‑κb signaling were detected using western blot analysis. |
2022-02-22 |
2023-08-13 |
Not clear |
| Jiabin Hong, Mengzhu Jiang, Lihao Guo, Juntong Lin, Yao Wang, Huanwen Tang, Xiaoshan Li. Prenatal exposure to triphenyl phosphate activated PPARγ in placental trophoblasts and impaired pregnancy outcomes. Environmental pollution (Barking, Essex : 1987). 2022-02-22. PMID:35192884. |
western blot analysis verified that the protein levels related to ers stress and apoptosis were significantly increased. |
2022-02-22 |
2023-08-13 |
mouse |
| Wei Liu, Dong Zhao, Xiaofeng Wu, Fang Yue, Haizhen Yang, Ke H. Rapamycin ameliorates chronic intermittent hypoxia and sleep deprivation-induced renal damage via the mammalian target of rapamycin (mTOR)/NOD-like receptor protein 3 (NLRP3) signaling pathway. Bioengineered. vol 13. issue 3. 2022-02-21. PMID:35184679. |
the sd+cih group demonstrated increased apoptosis compared with the control, sd, and cih groups using western blot analysis. |
2022-02-21 |
2023-08-13 |
mouse |