| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ziyun Lu, Zhiyi Liu, Bei Fan. Propofol protects cardiomyocytes from doxorubicin-induced toxic injury by activating the nuclear factor erythroid 2-related factor 2/glutathione peroxidase 4 signaling pathways. Bioengineered. vol 13. issue 4. 2022-04-01. PMID:35363601. |
ferroptosis was evaluated by corresponding kits and western blot and apoptosis was detected by cck-8, terminal deoxynucleotidyl transferase dutp nick-end labeling and western blot. |
2022-04-01 |
2023-08-13 |
human |
| Yi Zhang, Quanshu Di, Jiao Chen, Muyu Chang, Yalin Ma, Jianyun Y. Circ_0000263 facilitates the proliferation and inhibits the apoptosis of cervical cancer depending on the regulation of miR-1179/ABL2 axis. Reproductive sciences (Thousand Oaks, Calif.). 2022-03-31. PMID:35355231. |
the protein expression of proliferation markers, apoptosis markers and abl2 was detected by western blot analysis. |
2022-03-31 |
2023-08-13 |
Not clear |
| Pugui Li, Kun Zhang, Shijie Tang, Weizhu Tan. Knockdown of lncRNA HAGLROS inhibits metastasis and promotes apoptosis in nephroblastoma cells by inhibition of autophagy. Bioengineered. vol 13. issue 3. 2022-03-31. PMID:35358010. |
moreover, flow cytometric analysis and western blot assay were applied to evaluate cell apoptosis. |
2022-03-31 |
2023-08-13 |
Not clear |
| Nancy P Gómez-Crisóstomo, Selva Rivas-Arancibia, Erika Rodríguez-Martínez, Erick N De la Cruz-Hernández, Corazón de María Márquez Álvarez, Pablo Alexis Estrada Caraveo, Noemí Gelista Herrera, Marlen Valdés-Fuentes, Eduardo Martínez-Abundi. Chronic exposition to ozone induces cardiac antioxidant response and overexpression of either mitochondrial fision protein DRP1 and hipertrophyc-related proteins. Journal of bioenergetics and biomembranes. 2022-03-29. PMID:35347511. |
oxidative stress was evaluated by tbars and protein nitrosylation in addition to superoxide dismutase 1 (sod1) and catalase levels; the apoptosis related-proteins caspase 3, caspase 9, bax, bcl-2, and the mitochondrial dynamic-associated proteins fis1, drp1, opa1, and mfn1 were quantified by western blot among the cardiac hypertrophy indicator alpha-actin (cardiac actin). |
2022-03-29 |
2023-08-13 |
rat |
| Zhao Tang, Wenjing Du, Fei Xu, Xianjun Sun, Wenjing Chen, Jie Cui, Weifeng Tang, Fangyong Yang, Fangzhou Teng, Jinpei Lin, Baojun Liu, Jingcheng Don. Icariside II enhances cisplatin-induced apoptosis by promoting endoplasmic reticulum stress signalling in non-small cell lung cancer cells. International journal of biological sciences. vol 18. issue 5. 2022-03-28. PMID:35342361. |
the western blot results revealed that is activated endoplasmic reticulum (er) stress, including three branches of upr signalling, perk, ire1 and atf6, and the downstream perk-eif2α-atf4-chop pathway, thus potentiating the apoptosis induced by cisplatin. |
2022-03-28 |
2023-08-13 |
mouse |
| Mei-Dong Zhu, Qi Li, Jia-Qin Yuan, Fu-Chen Song, Sheng-Hua Liu, Lei Zhang, Cheng Zha. Alleviation of Diabetic Tendon Injury via Activation of Tendon Fibroblasts Autophagy under Berberine Treatment. Journal of visualized experiments : JoVE. issue 181. 2022-03-28. PMID:35343961. |
tendon fibroblasts were obtained from the rat achilles tendon, and the role of bbr in regulating cell apoptosis, the production of inflammatory cytokines, and autophagy activation were assessed using flow cytometry, quantitative real-time pcr (qrt-pcr), and western blot analysis. |
2022-03-28 |
2023-08-13 |
rat |
| Ai-Xue Chen, Rui-Ying Jin, Wei-Mei Zhou, Yong-Ju Ye, Jia-Li Lu, Yue-Fang Ren, Fei-Lan Xua. CircRNA circ_0043533 facilitates cell growth in polycystic ovary syndrome by targeting miR-1179. Reproductive biology. vol 22. issue 2. 2022-03-26. PMID:35338913. |
moreover, knockdown of circ_0043533 in ogc lines cov434 and kgn, respectively, the cell viability, proliferation, apoptosis, and cycle-related markers of insulin-triggered ogcs were examined by cck-8, edu staining, flow cytometry, and western blot assays, respectively. |
2022-03-26 |
2023-08-13 |
human |
| Weihan Yang, Runfeng Liu, Qinqiang Sun, Xingchen Huang, Junjun Zhang, Liangfeng Huang, Pengfei Zhang, Ming Zhang, Qiang F. Quercetin Alleviates Endoplasmic Reticulum Stress-Induced Apoptosis in Buffalo Ovarian Granulosa Cells. Animals : an open access journal from MDPI. vol 12. issue 6. 2022-03-25. PMID:35327186. |
apoptosis was detected by annexin fluorescein 5 isothiocyanate (v-fitc), and the expressions of mrna and related proteins involved in er stress and apoptosis were detected via real-time polymerase chain reaction and western blot. |
2022-03-25 |
2023-08-13 |
Not clear |
| Anna Kowalczuk, Nabila Bourebaba, Juliia Panchuk, Krzysztof Marycz, Lynda Bourebab. Calystegines Improve the Metabolic Activity of Human Adipose Derived Stromal Stem Cells (ASCs) under Hyperglycaemic Condition through the Reduction of Oxidative/ER Stress, Inflammation, and the Promotion of the AKT/PI3K/mTOR Pathway. Biomolecules. vol 12. issue 3. 2022-03-25. PMID:35327652. |
different cellular pathways including apoptosis, oxidative and er stress, inflammation as well as pi3k/akt/mtor metabolic-associated axis have been evaluated by means on rt-qpcr, western blot, and flow cytometry techniques. |
2022-03-25 |
2023-08-13 |
human |
| Dan Wang, Hao Qu, Hui Kang, Feng Xu, Wei Huang, Xianhua Ca. Kukoamine A attenuates lipopolysaccharide-induced apoptosis, extracellular matrix degradation, and inflammation in nucleus pulposus cells by activating the P13K/Akt pathway. Bioengineered. vol 13. issue 4. 2022-03-25. PMID:35333664. |
then, the experiments following the treatment of kua in lps-induced npcs included cell proliferation assessment by 5-ethynyl-2'-deoxyuridine (edu) kit, cell apoptosis and extracellular matrix degradation (ecm) analysis by terminal dutp nick-end labeling (tunel) and western blot, the detection of inflammatory cytokines by western blot and enzyme-linked immunosorbent assay (elisa), p13k/akt pathway-related protein levels analysis by western blot. |
2022-03-25 |
2023-08-13 |
Not clear |
| Hui Zhang, Yilei Che, Bin Xuan, Xiaozhen Wu, Hui L. Serine hydroxymethyltransferase 2 (SHMT2) potentiates the aggressive process of oral squamous cell carcinoma by binding to interleukin enhancer-binding factor 2 (ILF2). Bioengineered. vol 13. issue 4. 2022-03-25. PMID:35333683. |
western blot was adopted to detect the expression of factors related to apoptosis, migration, and epithelial-mesenchymal transition (emt). |
2022-03-25 |
2023-08-13 |
Not clear |
| Jian Wang, Yongzhen Huang, Jiawei Xu, Binglin Yue, Yifan Wen, Xiao Wang, Chuzhao Lei, Hong Che. PLAG1 promotes proliferation and inhibits apoptosis of bovine primary myoblasts through the PI3K-Akt signaling pathway. Journal of animal science. 2022-03-24. PMID:35325183. |
the plag1 was proved to promote the proliferation of bovine primary myoblasts using the cell counting kit 8 (cck-8) assay (p<0.001), 5-ethynyl-2'-deoxyuridine (edu) proliferation assay (p=0.005), quantitative real-time polymerase chain reaction (qrt-pcr) (p=0.028), western blot, and flow cytometry (p<0.05), and to inhibit apoptosis of bovine primary myoblasts using qrt-pcr (p=0.038), western blot, and flow cytometry (p<0.001). |
2022-03-24 |
2023-08-13 |
cattle |
| Jian Wang, Yongzhen Huang, Jiawei Xu, Binglin Yue, Yifan Wen, Xiao Wang, Chuzhao Lei, Hong Che. PLAG1 promotes proliferation and inhibits apoptosis of bovine primary myoblasts through the PI3K-Akt signaling pathway. Journal of animal science. 2022-03-24. PMID:35325183. |
chromatin immunoprecipitation sequencing (chip-seq) and western blot showed plag1 upregulated phosphorylated (p)-pi3k, pi3k, p-akt, akt, cyclin d1, and cdk2 and inhibited the expression of p21 and p27 to enhance myoblast proliferation, and increased expression of bcl-2, and bcl-xl to inhibit apoptosis. |
2022-03-24 |
2023-08-13 |
cattle |
| M Vomero, M Caliste, C Barbati, M Speziali, A I Celia, F Ucci, C Ciancarella, E Putro, T Colasanti, G Buoncuore, E Corsiero, M Bombardieri, F R Spinelli, F Ceccarelli, F Conti, C Alessandr. Tofacitinib Decreases Autophagy of Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients. Frontiers in pharmacology. vol 13. 2022-03-21. PMID:35308233. |
levels of autophagy, apoptosis, and citrullinated proteins were analyzed by western blot, flow cytometry, immunocytofluorescence, and real-time pcr. |
2022-03-21 |
2023-08-13 |
Not clear |
| Alice Nicolai, Samanta Taurone, Simone Carradori, Marco Artico, Antonio Greco, Roberta Costi, Susanna Scarp. The kinesin Eg5 inhibitor K858 exerts antiproliferative and proapoptotic effects and attenuates the invasive potential of head and neck squamous carcinoma cells. Investigational new drugs. 2022-03-21. PMID:35312942. |
the expression levels of cyclin b1 and several markers of apoptosis and invasion were studied by western blot. |
2022-03-21 |
2023-08-13 |
human |
| Nadine A Kerr, Juliana Sanchez, Gregory O'Connor, Brant D Watson, Sylvia Daunert, Helen M Bramlett, W Dalton Dietric. Inflammasome-Regulated Pyroptotic Cell Death in Disruption of the Gut-Brain Axis After Stroke. Translational stroke research. 2022-03-20. PMID:35306629. |
we examined the time course of inflammasome protein expression in brain and intestinal lysate using western blot analysis at 1-, 3-, and 7-days post-injury for caspase-1, interleukin-1β, nod-like receptor protein 3 (nlrp3), and apoptosis speck-like protein containing a caspase-recruiting domain (asc) and gasdermin-d (gsdmd) cleavage. |
2022-03-20 |
2023-08-13 |
mouse |
| Xue Bai, Xinyi Liu, Shuting Li, Hailong An, Xianjiang Kang, Shuai Gu. Nuciferine Inhibits TMEM16A in Dietary Adjuvant Therapy for Lung Cancer. Journal of agricultural and food chemistry. 2022-03-17. PMID:35298888. |
in addition, the signal transduction pathway of nuciferine regulating la795 cell proliferation, migration, and apoptosis was confirmed by western blot experiments. |
2022-03-17 |
2023-08-13 |
Not clear |
| Mei Yang, Egao Yin, Yiheng Xu, Yongjun Liu, Ting Li, Zhaoxing Dong, Wenlin Ta. CDKN2B antisense RNA 1 expression alleviates idiopathic pulmonary fibrosis by functioning as a competing endogenouse RNA through the miR-199a-5p/Sestrin-2 axis. Bioengineered. vol 13. issue 3. 2022-03-16. PMID:35291918. |
related protein levels were detected by western blot combined with cell counting kit-8 (cck-8), wound healing, and flow cytometry to analyze cell proliferation, migration, and apoptosis. |
2022-03-16 |
2023-08-13 |
mouse |
| Feng Gao, Yongcheng Zhao, Bin Zhang, Chunwei Xiao, Zhanfa Sun, Yuan Gao, Xueyong Do. SESN1 attenuates the Ox‑LDL‑induced inflammation, apoptosis and endothelial‑mesenchymal transition of human umbilical vein endothelial cells by regulating AMPK/SIRT1/LOX1 signaling. Molecular medicine reports. vol 25. issue 5. 2022-03-16. PMID:35293601. |
terminal deoxynucleotidyl transferase‑mediated nick‑end labeling staining was employed to detect cell apoptosis and western blot analysis was used to determine the levels of apoptosis‑related proteins. |
2022-03-16 |
2023-08-13 |
human |
| Wei He, Qian Wang, Weiping Sha, Liming Wang, Di Li, Gang Che. P2X4 Inhibition reduces microglia inflammation and apoptosis by NLRP3 and improves nervous system defects in rat brain trauma model. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 99. 2022-03-15. PMID:35290938. |
real-time pcr, western blot, immunofluorescence, apoptosis, brain water content and neurological score analysis were evaluated. |
2022-03-15 |
2023-08-13 |
rat |