| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ye Cao, Jiajia Zheng, Chentao L. Retracted Article: miR-199a-3p knockdown inhibits dedifferentiated liposarcoma (DDLPS) cell viability and enhances apoptosis through targeting casein kinase-1 alpha (CK1α). RSC advances. vol 9. issue 39. 2022-05-06. PMID:35519458. |
functionally, mtt assay, flow cytometry and western blot results demonstrated that knockdown of mir-199a-3p inhibited ddlps cell viability, enhanced apoptosis rate, and decreased expression of apoptosis-related genes bax and cleaved caspase 3, as well as increased bcl-2 expression |
2022-05-06 |
2023-08-13 |
Not clear |
| Xi Zhao, Siquan Zhang, Hongyi Sha. Dexpanthenol attenuates inflammatory damage and apoptosis in kidney and liver tissues of septic mice. Bioengineered. vol 13. issue 5. 2022-05-05. PMID:35510377. |
the apoptosis of kidney and liver tissues in clp-induced mice was assessed by means of terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) and western blot. |
2022-05-05 |
2023-08-13 |
mouse |
| Mingjia Zhang, Xuechun Li, Wenjing Wu, Jingxi Gao, Qin Han, Zhao Sun, Robert Chunhua Zha. Regorafenib induces the apoptosis of gastrointestinal cancer-associated fibroblasts by inhibiting AKT phosphorylation. Stem cells and development. 2022-05-03. PMID:35502476. |
then, we used mts and flow cytometry to detect the effects of regorafenib on the proliferation and apoptosis of cafs, and western blot to determine the expression level of apoptosis-related proteins. |
2022-05-03 |
2023-08-13 |
Not clear |
| Na Yu, Jun Li, Yuan Zhang, Dan Ding, Xiaolin Li, Huae X. Superior antitumor effect of self-assembly supramolecular paclitaxel nanoparticles. RSC advances. vol 10. issue 22. 2022-05-02. PMID:35492086. |
acridine orange/ethidium bromide double staining, apoptosis analysis and western blot were measured to explore the apoptotic cell death after ptx-nps or free ptx treatment. |
2022-05-02 |
2023-08-13 |
Not clear |
| Bo Chen, Xunfang Ding, Yanbo Yan. Hirudin Regulates Vascular Function in Chronic Renal Failure through Modulating Macrophage Polarization. BioMed research international. vol 2022. 2022-05-02. PMID:35496058. |
besides, western blot was to estimate the levels of marker proteins related to macrophage, proliferation, and apoptosis. |
2022-05-02 |
2023-08-13 |
rat |
| Guowen Li, Heyuan Luo, Zhiyong Ding, Haofeng Liang, Zhoupeng Lai, Shuzhen Chen, Yuliang Huan. Silencing of circ_0000205 mitigates interleukin-1β-induced apoptosis and extracellular matrix degradation in chondrocytes via targeting miR-766-3p/ADAMTS5 axis. Innate immunity. vol 28. issue 2. 2022-04-28. PMID:35484121. |
cell proliferation, apoptosis, and extracellular matrix (ecm) synthesis were examined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide and 5-ethynyl-2-deoxyuridine assays, flow cytometry, and qrt-pcr and western blot assays. |
2022-04-28 |
2023-08-13 |
Not clear |
| Ting Xu, Kun Wu, Jin Shi, Lindong Ji, Xudong Song, Guoquan Tao, Shutao Zheng, Li Zhang, Baofei Jian. LINC00858 promotes colon cancer progression through activation of STAT3/5 signaling by recruiting transcription factor RAD21 to upregulate PCNP. Cell death discovery. vol 8. issue 1. 2022-04-26. PMID:35468892. |
western blot was conducted to determine rad21, pcnp, phosphorylated (p)-stat3, stat3, p-stat5 and stat5 and apoptosis related proteins. |
2022-04-26 |
2023-08-13 |
mouse |
| Qi Wang, Yuan Li, Hong Tan, Yingwei Wan. Sevoflurane-Induced Apoptosis in the Mouse Cerebral Cortex Follows Similar Characteristics of Physiological Apoptosis. Frontiers in molecular neuroscience. vol 15. 2022-04-25. PMID:35465098. |
to determine whether the akt-foxo1-puma pathway contributes to the developmental decrease in magnitude of both physiological and sevoflurane-induced apoptosis, western blot was used to measure the levels of related proteins in s1 of p5 and p9 mice. |
2022-04-25 |
2023-08-13 |
mouse |
| Qin Liao, Xuefeng Ga. Tribbles homolog 3 contributes to high glucose-induced injury in retinal pigment epithelial cells via binding to growth factor receptor-bound 2. Bioengineered. vol 13. issue 4. 2022-04-25. PMID:35465829. |
cell apoptosis was assayed by tunel assay and western blot. |
2022-04-25 |
2023-08-13 |
human |
| Daniela Lobenwein, Rosalie Huber, Lars Kerbler, Alexandra Gratl, Sabine Wipper, Can Gollmann-Tepeköylü, Johannes Holfel. Neuronal Pre- and Postconditioning via Toll-like Receptor 3 Agonist or Extracorporeal Shock Wave Therapy as New Treatment Strategies for Spinal Cord Ischemia: An In Vitro Study. Journal of clinical medicine. vol 11. issue 8. 2022-04-23. PMID:35456206. |
we measured cytokine expression via rt-pcr and utilized western blot analysis for the analysis of signaling and apoptosis. |
2022-04-23 |
2023-08-13 |
Not clear |
| Zhihui Huang, Genyang Ji. Licochalcone B induced apoptosis and autophagy in osteosarcoma tumor cells via the inactivation of PI3K/AKT/mTOR pathway. Biological & pharmaceutical bulletin. 2022-04-18. PMID:35431285. |
furthermore, flow cytometry and western blot revealed that licb promoted autophagy and apoptosis in os cells in a dose-dependent manner. |
2022-04-18 |
2023-08-13 |
Not clear |
| Wei Zhang, Qi Zh. Punicalagin suppresses inflammation in ventilator-induced lung injury through PAR2 inhibition-induced inhibition of NLRP3 inflammasome activation. Chemical biology & drug design. 2022-04-18. PMID:35434894. |
the levels of inflammatory cytokines (tumor necrosis factor (tnf)-α, interleukin (il)-1β, and il-6), par2, nlr family pyrin domain containing-3 (nlrp3) and apoptosis associated speck-like protein containing a card (asc) in the balf lungs or cells were analyzed by enzyme-linked immune-sorbent assay (elisa), qrt-pcr or/and western blot. |
2022-04-18 |
2023-08-13 |
mouse |
| Tongde Wu, Xuebing Jia, Ziqi Zhu, Kai Guo, Qiang Wang, Zhiqiang Gao, Xinhua Li, Yufeng Huang, Desheng W. Inhibition of miR-130b-3p restores autophagy and attenuates intervertebral disc degeneration through mediating ATG14 and PRKAA1. Apoptosis : an international journal on programmed cell death. 2022-04-18. PMID:35435532. |
apoptosis, senescence, and autophagy were evaluated by flow cytometry, β-gal staining, immunofluorescence, electron microscopy, and western blot in the mir-130b-3p knocked down human np cells under tbhp treatment. |
2022-04-18 |
2023-08-13 |
human |
| Zhentian Wu, Lianghua Wu, Liangliang Zou, Muqing Wang, Xin Li. Metformin induces myeloma cells necrosis and apoptosis and it is considered for therapeutic use. Journal of chemotherapy (Florence, Italy). 2022-04-15. PMID:35427214. |
apoptosis, necrosis, cell cycle arrest, and cell death mechanisms were explored via flow cytometry (fcm) and western blot. |
2022-04-15 |
2023-08-13 |
mouse |
| Shuyan Sheng, Wenzhuo Su, Deshen Mao, Conghan Li, Xinyang Hu, Wanyu Deng, Yong Yao, Yongsheng J. MicroRNA-21 induces cisplatin resistance in head and neck squamous cell carcinoma. PloS one. vol 17. issue 4. 2022-04-14. PMID:35421166. |
reverse transcription-pcr to detect expression, mtt and clonogenic assays to evaluate cell proliferation, apoptosis assays, resazurin cell viability assays, western blot and luciferase reporter assays to detect protein expression, and flow cytometry to analyse the cell cycle were adopted. |
2022-04-14 |
2023-08-13 |
Not clear |
| Samson Eugin Simon, Usman Ahmed, Syed Muhammad Saad, Ayaz Anwar, Khalid Mohammed Khan, Ee Wern Tan, Kuan Onn Ta. New synthetic phenylquinazoline derivatives induce apoptosis by targeting the pro-survival members of the BCL-2 family. Bioorganic & medicinal chemistry letters. 2022-04-14. PMID:35421577. |
western blot analysis showed that both sms-iv-20 and sms-iv-40 induced down-regulation of bcl-2 or both bcl-2 and bcl-xl expression, respectively while promoting the release of mitochondrial cytochrome c. taken together, the data showed that sms-iv-20 and sms-iv-40 are potent activators of apoptosis that enhance chemo-sensitization through their antagonistic actions on the pro-survival activity of the bcl-2 family in human cancer cells. |
2022-04-14 |
2023-08-13 |
human |
| Merve Yildirim, Ozgecan Kayalar, Ersan Atahan, Fusun Ozta. Atorvastatin attenuates pulmonary fibrosis in mice and human lung fibroblasts, by the regulation of myofibroblast differentiation and apoptosis. Journal of biochemical and molecular toxicology. 2022-04-13. PMID:35416377. |
the effects of atr on myofibroblast differentiation, apoptosis, and tgf-β and wnt/β-catenin signaling activations were examined by western blot analysis and flow cytometry in mrc5s. |
2022-04-13 |
2023-08-13 |
mouse |
| Yile Cao, Hui Chen, Yu Sun, Zhehao Fan, Hong Chen. Quercetin inhibits fibroblasts proliferation and reduces surgery-induced epidural fibrosis via the autophagy-mediated PI3K/Akt/mTOR pathway. Bioengineered. vol 13. issue 4. 2022-04-12. PMID:35412948. |
the results showed that quercetin had significant suppressive effects on epidural fibrosis following laminectomy in rats.in vitro,, cell counting kit-8 (cck-8), western blot analysis, immunofluorescence and edu staining, tunel staining and transmission electron microscopy were used to detect the effects of quercetin on the proliferation and apoptosis of fibroblasts and explore the possible signal transduction pathway. |
2022-04-12 |
2023-08-13 |
Not clear |
| Sajedeh Daei, Roghayeh Abbasalipourkabir, Maryam Khajvand-Abedini, Nasrin Ziamajid. The Alleviative Efficacy of Vitamins A, C, and E Against Zinc Oxide Nanoparticles-Induced Hepatic Damage by Reducing Apoptosis in Rats. Biological trace element research. 2022-04-02. PMID:35364806. |
to investigate apoptosis, the mrna and protein expression of bcl-2-associated x (bax) and b-cell lymphoma protein 2 (bcl-2) were examined by qrt-pcr and western blot techniques. |
2022-04-02 |
2023-08-13 |
human |
| Hongting Tang, Daoqiu Wu, Hanlin Yang, Juan Yang, Yi Zhang, Mengxing Li, Honglin Liu, Qinshan L. [Inhibition of autophagy enhances apoptosis induced by doxorubicin hydrochloride in human colon cancer cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 3. 2022-04-02. PMID:35365989. |
western blot was used to detect the effect of inhibiting autophagy on apoptosis, with 3-methyladenine (3-ma) group and 3-ma combined with dox group supplemented. |
2022-04-02 |
2023-08-13 |
human |