| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Liu, Liping Zhao, Dan Yan, Na Wan. Circ_0060,144 inhibits the occurrence and development of age-related cataract via the miR-23b-3p/HIPK3 axis. Experimental eye research. 2022-07-10. PMID:35810770. |
western blot was performed to measure protein-associated proliferation and apoptosis. |
2022-07-10 |
2023-08-14 |
Not clear |
| Yi He, Salvador Alejo, Prabhakar Pitta Venkata, Jessica D Johnson, Ilanna Loeffel, Uday P Pratap, Yi Zou, Zhao Lai, Rajeshwar R Tekmal, Edward R Kost, Gangadhara R Saredd. Therapeutic Targeting of Ovarian Cancer Stem Cells Using Estrogen Receptor Beta Agonist. International journal of molecular sciences. vol 23. issue 13. 2022-07-09. PMID:35806169. |
western blot and rt-qpcr assays demonstrated the upregulation of apoptosis and cell cycle arrest genes such as fdxr, p21/cdkn1a, cleaved parp, and caspase 3, and the downregulation of stemness markers sox2, oct4, and nanog. |
2022-07-09 |
2023-08-14 |
Not clear |
| Saereh Hosseindoost, Ardeshir Akbarabadi, Mitra-Sadat Sadat-Shirazi, Seyed M Mousavi, Solmaz Khalifeh, Azarakhsh Mokri, Mahmoudreza Hadjighassem, Mohammad-Reza Zarrindas. Effect of tramadol on apoptosis and synaptogenesis in hippocampal neurons: The possible role of µ-opioid receptor. Drug development research. 2022-07-09. PMID:35808942. |
the western blot analysis technique was performed for the assessment of apoptosis and synaptogenesis markers. |
2022-07-09 |
2023-08-14 |
rat |
| Zhang Yang, Wang Yaling, Liu Tao, Rao Mingyue, Li Yongju. Cardioprotective effect of NRG-4 gene expression on spontaneous hypertension rats and its mechanism through mediating the activation of ErbB signaling pathway. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 1. 2022-07-09. PMID:35809324. |
quantitative real-time polymerase chain reaction (qrt-pcr) and western blot were used to detect the expression levels in addition, methyl thiazolyl tetrazolium salt (mtt) assay and flow cytometry were performed to detect the proliferation and apoptosis of cardiomyocytes, respectively. |
2022-07-09 |
2023-08-14 |
rat |
| Shujing Li, Yanyan Zhang, Jin Zhang, Bo Yu, Weiran Wang, Baosong Jia, Jingtao Chang, Jing Li. Neferine Exerts Ferroptosis-Inducing Effect and Antitumor Effect on Thyroid Cancer through Nrf2/HO-1/NQO1 Inhibition. Journal of oncology. vol 2022. 2022-07-07. PMID:35794985. |
the effect of neferine on the proliferation, apoptosis, invasion, vascular endothelial growth factor (vegf), epithelial-mesenchymal transition (emt), and ferroptosis was evaluated by cck-8, flow cytometry, western blot, and spectrophotometry assays. |
2022-07-07 |
2023-08-14 |
Not clear |
| Da Teng, Shaoyou Xia, Shidong Hu, Yang Yan, Boyan Liu, Yu Yang, Xiaohui D. miR-887-3p Inhibits the Progression of Colorectal Cancer via Downregulating DNMT1 Expression and Regulating P53 Expression. Computational intelligence and neuroscience. vol 2022. 2022-07-07. PMID:35795731. |
following mir-887-3p mimic transfection in colon cancer sw480 cell line, the regulatory roles of mir-887-3p on cell proliferation, apoptosis, invasion, migration, and epithelial-mesenchymal transition (emt) were detected through cck-8, flow cytometry, transwell assay, and western blot. |
2022-07-07 |
2023-08-14 |
Not clear |
| Xu Wang, Xinyu Zhang, Kexin Sun, Shengchen Wang, Duqiang Gon. Polystyrene microplastics induce apoptosis and necroptosis in swine testis cells via ROS/MAPK/HIF1α pathway. Environmental toxicology. 2022-07-06. PMID:35791677. |
acridine orange/ethidium bromide staining and flow cytometry results indicated the occurrence of apoptosis and necrosis in st cells under ps-mps exposure, and the expression changes of relevant marker genes (b-cell lymphoma-2, bcl-2 associated x, caspase-3, caspase-9, receptor-interacting protein kinase 1, receptor-interacting protein kinase 3, mixed lineage kinase domain-like, and caspase-8) were clarified via quantitative real-time pcr and western blot. |
2022-07-06 |
2023-08-14 |
human |
| Yutao Guan, Qianlong Wu, Miaomiao Li, Danyang Chen, Jingyao Su, Liandong Zuo, Bing Zhu, Yinghua L. Epigallocatechin-3-gallate induced HepG2 cells apoptosis through ROS-Mediated AKT /JNK and p53 signaling pathway.. Current cancer drug targets. 2022-07-06. PMID:35792125. |
methods the effect of egcg on the apoptosis of hep-g2 cells and its mechanism were studied by cell counting kit-8, mitochondrial membrane potential assay with jc-1, annexin v-fitc apoptosis detection, cell cycle, and apoptosis analysis, one step tunel apoptosis assay, caspase 3 activity assay, caspase 9 activity assay, reactive oxygen species assay, and western blot. |
2022-07-06 |
2023-08-14 |
Not clear |
| Hanlin Wang, Chengyao Chiang, Chenyang Xue, Lu Zhou, Shuaihu Li, Yaqi Zhou, Zhucheng Zhang, Meng Xie, Tian Xiao, Hongyi Hu, Lizhi Zhu, Cheng Long, Yongdong Zou, Ting Wang, Duo Zhen. Dezocine induces apoptosis in human cervical carcinoma Hela cells via the endoplasmic reticulum stress pathway. Toxicology research. vol 11. issue 3. 2022-07-05. PMID:35782639. |
in addition, the role of endoplasmic reticulum (er) stress in dezocine-induced apoptosis was investigated using qpcr and western blot analysis. |
2022-07-05 |
2023-08-14 |
human |
| Susana Jurado, Albert Parés, Pilar Peris, Andreu Combalia, Ana Monegal, Núria Guañaben. Bilirubin increases viability and decreases osteoclast apoptosis contributing to osteoporosis in advanced liver diseases. Bone. 2022-07-05. PMID:35787483. |
cell viability was measured using wst-1 assay and apoptosis assessing caspase-3 by western blot. |
2022-07-05 |
2023-08-14 |
human |
| Ting Wang, Jingmin Zhang, Meng Yang, Jinxiu Guo, Duolu Li, Ying L. Lipidomics Analysis Reveals a Protective Effect of Myriocin on Cerebral Ischemia/Reperfusion Model Rats. Journal of molecular neuroscience : MN. 2022-07-01. PMID:35776315. |
moreover, tunel and western blot assays showed that myriocin plays a key role in regulating neuronal cell apoptosis. |
2022-07-01 |
2023-08-14 |
rat |
| Yueh-Min Lin, Jiro Hasegawa Situmorang, Jia-Zun Guan, Dennis Jine-Yuan Hsieh, Jaw-Ji Yang, Michael Yu-Chih Chen, Ching-Hui Loh, Chia-Hua Kuo, Shang-Yeh Lu, Ying-Ming Liou, Chih-Yang Huan. ZAKβ Alleviates Oxidized Low-density Lipoprotein (ox-LDL)-Induced Apoptosis and B-type Natriuretic Peptide (BNP) Upregulation in Cardiomyoblast. Cell biochemistry and biophysics. 2022-07-01. PMID:35776316. |
western blot was used to detect apoptosis, hypertrophy, and pro-survival signaling proteins. |
2022-07-01 |
2023-08-14 |
Not clear |
| Xiaoxue Tian, Zeyu Zhu, Guangming Wang, Jun Xu, Aibin Liang, Wenjun Zhan. Inhibition of DEK Enhances Doxorubicin-Induced Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia Cells. Disease markers. vol 2022. 2022-06-30. PMID:35769815. |
western blot analysis was performed to determine protein expression of apoptosis and cell cycle-related genes, including bcl2l1, caspase-3, and cyclin-dependent kinases (cdk). |
2022-06-30 |
2023-08-14 |
mouse |
| Xiaoxue Tian, Zeyu Zhu, Guangming Wang, Jun Xu, Aibin Liang, Wenjun Zhan. Inhibition of DEK Enhances Doxorubicin-Induced Apoptosis and Cell Cycle Arrest in T-Cell Acute Lymphoblastic Leukemia Cells. Disease markers. vol 2022. 2022-06-30. PMID:35769815. |
western blot results showed that dox treatment leads to cell cycle arrest, reduction of cyclin-dependent kinase 6 (cdk6) protein, accumulation of cdkn1a protein, and dox-induced apoptosis accompanied by reductions in protein levels of bcl2l1, as well as increases in protein level of caspase-3. |
2022-06-30 |
2023-08-14 |
mouse |
| Ding Wan, Xiaoyan Wang, Jin Feng, Peng Wang, Hua X. Inhibitory effect of PDE2 on inflammation and apoptosis in cerebral ischemia‑reperfusion injury. International journal of molecular medicine. vol 50. issue 2. 2022-06-28. PMID:35762318. |
the levels of apoptosis were subsequently determined using tunel and western blot analysis. |
2022-06-28 |
2023-08-14 |
mouse |
| Zinab Mohammadi, Jahanbakhsh Asadi, Seyyed Mehdi Jafar. Synergistic effects of BAY606583 on docetaxel in esophageal cancer through modulation of ERK1/2. Cell biochemistry and function. 2022-06-27. PMID:35758556. |
subsequently, apoptosis was assessed by annexin-v and propidium iodide staining, and bcl-2, bax, and erk1/2 protein-level expressions were evaluated by western blot. |
2022-06-27 |
2023-08-14 |
Not clear |
| Yanjun X. MiRNA-21-5p Accelerates EMT and Inhibits Apoptosis of Laryngeal Carcinoma via Inhibiting KLF6 Expression. Biochemical genetics. 2022-06-27. PMID:35761154. |
western blot was used to detect apoptosis and epithelial-mesenchymal transition (emt) related proteins. |
2022-06-27 |
2023-08-14 |
Not clear |
| Michael J Viereckl, Kelsey Krutsinger, Aaron Apawu, Jian Gu, Bryana Cardona, Donovan Barratt, Yuyan Ha. Cannabidiol and Cannabigerol Inhibit Cholangiocarcinoma Growth In Vitro via Divergent Cell Death Pathways. Biomolecules. vol 12. issue 6. 2022-06-24. PMID:35740979. |
in addition, the expression of autophagy gene lc3b and apoptosis genes bax, bcl-2, and cleaved caspase-3 were evaluated via western blot. |
2022-06-24 |
2023-08-14 |
Not clear |
| Feng Luo, Jinbang Li, Jihong Liu, Kunping Li. Stabilizing and upregulating Axin with tankyrase inhibitor reverses 5-fluorouracil chemoresistance and proliferation by targeting the WNT/caveolin-1 axis in colorectal cancer cells. Cancer gene therapy. 2022-06-24. PMID:35750753. |
apoptosis induced by 5-fu, cell cycle distribution and expression levels of wnt/β-catenin/tcf12/caveolin-1 and multidrug resistance proteins were examed by flow cytometry and western blot after β-catenin activation/inhibition and caveolin-1 overexpression/interference. |
2022-06-24 |
2023-08-14 |
mouse |
| Lizha Mary Lazer, Yasodha Kesavan, Ravi Gor, Ilangovan Ramachandran, Surajit Pathak, Shoba Narayan, Muralidharan Anbalagan, Satish Ramalinga. Targeting colon cancer stem cells using novel doublecortin like kinase 1 antibody functionalized folic acid conjugated hesperetin encapsulated chitosan nanoparticles. Colloids and surfaces. B, Biointerfaces. vol 217. 2022-06-23. PMID:35738074. |
in this regard, we have performed proliferation assay, colony formation assay, cell migration assay, apoptosis assay, flow cytometry analysis, real-time rt- pcr and western blot analyses to determine the effect of cfh-dclk1 and cfh nanoparticles in hct116-colon cancer cells. |
2022-06-23 |
2023-08-14 |
Not clear |