| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Huanyuan Wang, Jingtao Wu, Haiyin Fan, Yuan Ji, Chunbin Han, Chao Li, Sicong Jian. The Impact of Catalpol on Proliferation, Apoptosis, Migration, and Oxidative Stress of Lung Cancer Cells Based on Nrf2/ARE Signaling. BioMed research international. vol 2022. 2022-07-28. PMID:35898682. |
proliferation was detected using the cck-8 assay; apoptosis was detected using flow cytometry; migration was detected using the transwell chamber; ros was distinguished using the dcfhda method; mda, sod, and gsh were detected using the microvolume method; and cleaved caspase-3, cleaved caspase-9, nrf2, ho-1, mmp-9, and mmp-2 were detected using the western blot method. |
2022-07-28 |
2023-08-14 |
Not clear |
| Qi Tang, Yanghai Zhang, Linxiu Yue, Hongying Ren, Chuanying Pa. Ssc-MiR-21-5p and Ssc-MiR-615 Regulates the Proliferation and Apoptosis of Leydig Cells by Targeting SOX5. Cells. vol 11. issue 14. 2022-07-27. PMID:35883696. |
western blot and tunel assay indicated mir-615 inhibited apoptosis, but had no effect on proliferation. |
2022-07-27 |
2023-08-14 |
mouse |
| Yue-Mei Sun, Xin-Yue Wang, Xin-Ru Zhou, Chong Zhang, Ke-Jian Liu, Fu-Yin Zhang, Bin Xian. Salidroside Ameliorates Radiation Damage by Reducing Mitochondrial Oxidative Stress in the Submandibular Gland. Antioxidants (Basel, Switzerland). vol 11. issue 7. 2022-07-27. PMID:35883904. |
cell apoptosis was determined by western blot and tunel assays. |
2022-07-27 |
2023-08-14 |
rat |
| Omar Prado-Carrillo, Abner Arenas-Ramírez, Monserrat Llaguno-Munive, Rafael Jurado, Jazmin Pérez-Rojas, Eduardo Cervera-Ceballos, Patricia Garcia-Lope. Ketoconazole Reverses Imatinib Resistance in Human Chronic Myelogenous Leukemia K562 Cells. International journal of molecular sciences. vol 23. issue 14. 2022-07-27. PMID:35887063. |
the following parameters were determined in both cell lines: cell viability (as the ic50) after exposure to imatinib and imatinib + ketoconazole, p-gp expression (by western blot and immunofluorescence), the intracellular accumulation of a p-gp substrate (doxorubicin) by flow cytometry, and the percentage of apoptosis (by the annexin method). |
2022-07-27 |
2023-08-14 |
human |
| Farogh Ahsan, Tarique Mahmood, Tanveer A Wani, Seema Zargar, Mohammed Haris Siddiqui, Shazia Usmani, Arshiya Shamim, Muhammad Wahajuddi. Effectual Endeavors of Silk Protein Sericin against Isoproterenol Induced Cardiac Toxicity and Hypertrophy in Wistar Rats. Life (Basel, Switzerland). vol 12. issue 7. 2022-07-27. PMID:35888151. |
the grading of heart, heart/body weight ratio, gross morphology, cardiac markers, oxidative stress markers in serum and heart tissue, glucose, serum lipid profiling and lysosomal hydrolases, heart apoptotic markers such as mhc expression by western blot, apoptosis by flow cytometry, total myocardial collagen content, fibrosis estimation, myocyte size were significantly decreased when compared with isoproterenol (isg) group however histopathological studies showed normal architecture of heart in both control and treated rats. |
2022-07-27 |
2023-08-14 |
rat |
| Kai Liu, Xiao-E Fan, Li Zhang, Ying Yang, Xiao-Ling Zho. Circ-NCX1 inhibits LPS-induced chondrocyte apoptosis by regulating the miR-133a/SIRT1 axis. The Kaohsiung journal of medical sciences. 2022-07-27. PMID:35894157. |
the apoptosis was determined by flow cytometry, whereas the expression of apoptosis proteins was detected by western blot. |
2022-07-27 |
2023-08-14 |
Not clear |
| Xiaoqiang Zheng, Gang Wang, Jiang Yuan, Nuoya Li, Biaolei Yan, Jinlong Yan, Yanling Shen. hsa-miR-34a-5p Ameliorates Hepatic Ischemia/Reperfusion Injury Via Targeting HNF4α. The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology. vol 33. issue 7. 2022-07-26. PMID:35879917. |
cell apoptosis was detected by flow cytometry, western blot, and terminal deoxynucleotidyl transferase-mediated dutp nick-end labeling, respectively. |
2022-07-26 |
2023-08-14 |
rat |
| Jiangqi Xu, Xiaohong Huang, Shixiang Liu, Dongdong Chen, Yufang Xie, Zhenwu Zha. The protective effects of lncRNA ZFAS1/miR-421-3p/MEF2C axis on cerebral ischemia-reperfusion injury. Cell cycle (Georgetown, Tex.). 2022-07-26. PMID:35880950. |
overexpressed or silenced plasmids of zfas1 were transfected into the cells to analyze the effects of oxygen-glucose deprivation/reperfusion (ogd/r) treatment on the viability, apoptosis and related gene expressions of neuro-2a cell by performing mtt assay, flow cytometry, qrt-pcr, and western blot. |
2022-07-26 |
2023-08-14 |
mouse |
| Yaoying Zeng, Yanbin Pan, Bo Zhang, Yingbin Luo, Jianhui Tian, Yuli Wang, Xudong Ju, Jianchun Wu, Yan L. Integrating Network Pharmacology, Molecular Docking, and Experimental Validation to Investigate the Mechanism of (-)-Guaiol Against Lung Adenocarcinoma. Medical science monitor : international medical journal of experimental and clinical research. vol 28. 2022-07-25. PMID:35871777. |
in addition, cell-based verification, including the cck-8 assay, cell death assessment, apoptosis analysis, and western blot, was performed to determine the mechanism of action of (-)-guaiol. |
2022-07-25 |
2023-08-14 |
human |
| Yonghui Zhang, Haoyang Zhang, Jinage Mu, Meiyue Han, Zhihao Cao, Feng Dong, Tingting Wang, Lian Pan, Wujing Luo, Jiaxin Li, Huan Liu, Lishan Jin, Wenxuan Ding, Yong Wei, Xuesong Deng, Dan Liu, Xiuzhen He, Yi Pang, Xiao Mu, Zhongjun Wu, Dilong Che. Eupalinolide B inhibits hepatic carcinoma by inducing ferroptosis and the ROS-ER-JNK signaling pathway. Acta biochimica et biophysica Sinica. 2022-07-22. PMID:35866605. |
then, we investigate cell cycle, cell apoptosis, cell necrosis, cell autophagy, and ferroptosis by flow cytometry, western blot analysis and electron microscopy. |
2022-07-22 |
2023-08-14 |
human |
| Taiding Wu, Xin Li, Shiwei Tu, Wenbo Tan, Longju Che. Curcumin protect Schwann cells from inflammation response and apoptosis induced by high glucose through the NF-κB pathway. Tissue & cell. vol 77. 2022-07-22. PMID:35868051. |
first we verified that 150 mm high glucose can increase the expression of cleaved caspase 3, interleukin (il)- 1β, cyto-c and nf-κb with time through western blot and increase the apoptosis of rsc96s through flow cytometry. |
2022-07-22 |
2023-08-14 |
Not clear |
| Yei-Jin Kang, Won-Geun Yang, Weon-Sik Chae, Dae-Won Kim, Seong-Gon Kim, Horatiu Rotar. Administration of 4‑hexylresorcinol increases p53‑mediated transcriptional activity in oral cancer cells with the p53 mutation. Oncology reports. vol 48. issue 3. 2022-07-20. PMID:35856441. |
to determine the effect of 4hr on p53 mutant carcinoma cells, western blot analysis, p53 transcriptional activity analysis, mtt assay and apoptosis immunocytochemistry were performed. |
2022-07-20 |
2023-08-14 |
human |
| Gil-Sun Park, Bokyung Park, Mi-Young Le. Berberine Induces Autophagic Cell Death by Inactivating the Akt/mTOR Signaling Pathway. Planta medica. 2022-07-19. PMID:35853472. |
however, western blot analysis of apoptosis-related marker proteins showed that the expression of bcl-2, an apoptosis inhibitory protein, and the bcl-2/bax ratio were increased. |
2022-07-19 |
2023-08-14 |
Not clear |
| Xiangguang Shi, Yahui Chen, Kai Yang, Yifei Zhu, Yanyun Ma, Qingmei Liu, Ji'an Wang, Chunya Ni, Yue Zhang, Haiyang Li, Jinran Lin, Jiucun Wang, Wenyu W. Disrupted citric acid metabolism inhibits hair growth. The Journal of dermatology. 2022-07-16. PMID:35841232. |
the inflammation and apoptosis levels in mice, hfs, and dpcs were detected by immunohistofluorescence, qpcr, elisa, western blot, and tunel assay. |
2022-07-16 |
2023-08-14 |
mouse |
| Wenyue Zhang, Kai Yin, Jiahui Shi, Xu Shi, Xue Qi, Hongjin Li. The decrease of selenoprotein K induced by selenium deficiency in diet improves apoptosis and cell progression block in chicken liver via the PTEN/PI3K/AKT pathway. Free radical biology & medicine. 2022-07-16. PMID:35841984. |
through using tunel, tem, western blot and qrt-pcr we found apoptosis occurred in chicken liver in the selk-deficiency groups. |
2022-07-16 |
2023-08-14 |
chicken |
| Jing Wu, Gaifang Liu, Kang An, Linping Sh. NPTX1 inhibits pancreatic cancer cell proliferation and migration and enhances chemotherapy sensitivity by targeting RBM10. Oncology letters. vol 23. issue 5. 2022-07-15. PMID:35836482. |
cell apoptosis and the expression levels of apoptosis-related proteins were determined by tunel assay and western blot analysis, respectively. |
2022-07-15 |
2023-08-14 |
Not clear |
| Fangyi Chen, Zhe Ge, Nan Li, Zuochong Yu, Rongbo Wu, Yan Zhao, Xianwei He, Guoping Ca. TUDCA protects against tunicamycin-induced apoptosis of dorsal root ganglion neurons by suppressing activation of ER stress. Experimental and therapeutic medicine. vol 24. issue 2. 2022-07-15. PMID:35837048. |
the protein levels and phosphorylation of apoptosis and ers-related signaling pathway molecules were detected by western blot, and the mrna levels of related genes were assessed by reverse transcription-quantitative pcr. |
2022-07-15 |
2023-08-14 |
rat |
| Zhihai Yuan, Zhen Yang, Weiqin Li, Aimei Wu, Zhixiang Su, Bin Jiang, Sakthivigneswari Ganesa. Triphlorethol-A attenuates U251 human glioma cancer cell proliferation and ameliorates apoptosis through JAK2/STAT3 and p38 MAPK/ERK signaling pathways. Journal of biochemical and molecular toxicology. 2022-07-15. PMID:35838116. |
the cytotoxicity, intracellular reactive oxygen species (ros), matrix metalloproteinase (mmp), and cell apoptosis activity of ta have been evaluated by the mtt assay and by dcfh-da, rh-123, ao/eb, and western blot analysis. |
2022-07-15 |
2023-08-14 |
human |
| Xiaoli Gao, Qiaoli Yang, Shengwei Zhang, Xiaoyu Huang, Zunqiang Yan, Pengfei Wang, Shuangbao Gu. LncRNA ALDB-898 modulates intestinal epithelial cell damage caused by Clostridium perfringens type C in piglet by regulating ssc-miR-122-5p/OCLN signaling. Molecular immunology. vol 149. 2022-07-14. PMID:35834877. |
cytometry kit 8 (cck-8), lactate dehydrogenase (ldh), real-time quantitative polymerase chain reaction (rt-qpcr), western blot, flow cytometry and fluorescein isothiocyanate-dextran 4 (fitc-dextran 4) flux assays were performed to study the effect of aldb-898 and ssc-mir-122-5p in apoptosis, inflammation and intestinal barrier damage and inflammatory in ipec-j2 cells induced by cpb2. |
2022-07-14 |
2023-08-14 |
Not clear |
| Shiyu Zhou, Yu Lan, Yuqun Li, Zhenxing Li, Jinding Pu, Liping We. Hypoxic Tumor-Derived Exosomes Induce M2 Macrophage Polarization via PKM2/AMPK to Promote Lung Cancer Progression. Cell transplantation. vol 31. 2022-07-12. PMID:35818293. |
cck-8 assay, flow cytometry, western blot, wound healing, and transwell assays were performed to assess the proliferation, apoptosis, migration, and invasion of a549 cells, respectively. |
2022-07-12 |
2023-08-14 |
mouse |