| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' Seda \\xc5\\x9eirin, Hatice G\\xc3\\xbcl Dursun, Canan Ero\\xc4\\x9flu G\\xc3\\xbcne\\xc5\\x9. Composition analysis of Salsola grandis and its effects on colon cancer cells. Anti-cancer agents in medicinal chemistry. 2022-10-28. PMID:36305129.' |
we applied 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide, the thiazolyl blue (mtt) method to evaluate its effects on cell viability, elisa assay, real time pcr and western blot method to reveal its effects on apoptosis. |
2022-10-28 |
2023-08-14 |
Not clear |
| Rajina Shakya, Gyu Hwan Park, Sang Hoon Joo, Jung-Hyun Shim, Joon-Seok Cho. Hydroxyzine Induces Cell Death in Triple-Negative Breast Cancer Cells via Mitochondrial Superoxide and Modulation of Jak2/STAT3 Signaling. Biomolecules & therapeutics. vol 30. issue 6. 2022-10-28. PMID:36305293. |
western blot analysis showed that hydroxyzine-induced apoptosis was through down-regulation of the phosphorylation of jak2 and stat3 by hydroxyzine treatment. |
2022-10-28 |
2023-08-14 |
human |
| Qifang Niu, Yang Yang, Delong Li, Wenwen Guo, Chong Wang, Haoyue Xu, Zhien Feng, Zhengxue Ha. Exosomes Derived from Bone Marrow Mesenchymal Stem Cells Alleviate Ischemia-Reperfusion Injury and Promote Survival of Skin Flaps in Rats. Life (Basel, Switzerland). vol 12. issue 10. 2022-10-27. PMID:36295004. |
apoptosis was evaluated via the terminal deoxynucleotidyl transferase dutp nick-end labeling (tunel) assay and western blot analysis of bax, bcl-2. |
2022-10-27 |
2023-08-14 |
human |
| Aleksandra Jovanović Galović, Nataša Jovanović Lješković, Senka Vidović, Jelena Vladić, Nikola Jojić, Milan Ilić, Tatjana Srdić Rajić, Vesna Kojić, Dimitar Jakimo. The Effects of Resveratrol-Rich Extracts of Pharmaceutics. vol 14. issue 10. 2022-10-27. PMID:36297452. |
the cytotoxic effect is assessed by the mtt test and eb/ao staining, levels of apoptosis are determined by annexin v assay, autophagia by ulk-1 expression using western blot and nf-kb activation by p65 elisa. |
2022-10-27 |
2023-08-14 |
Not clear |
| Gaojie Song, Chao Shang, Yilong Zhu, Zhiru Xiu, Yaru Li, Xia Yang, Chenchen Ge, Jicheng Han, Ningyi Jin, Yiquan Li, Xiao Li, Jinbo Fan. Apoptin inhibits glycolysis and regulates autophagy by targeting pyruvate kinase M2 (PKM2) in lung cancer A549 cells. Current cancer drug targets. 2022-10-26. PMID:36284386. |
moreover, the effects of ad-apoptin on autophagy and apoptosis were analyzed by immunofluorescence using the annexin v-mcherry staining and by western blot for c-parp, p62 and lc3-ii proteins. |
2022-10-26 |
2023-08-14 |
mouse |
| Jingzhi Shao, Zhouxian Bai, Lirong Zhang, Fengyan Zhan. Ferrostatin-1 alleviates tissue and cell damage in diabetic retinopathy by improving the antioxidant capacity of the Xc Cell death discovery. vol 8. issue 1. 2022-10-25. PMID:36284090. |
western blot was used to detect the expression of apoptosis and pyroptosis-related proteins. |
2022-10-25 |
2023-08-14 |
rat |
| Zhi Chen, QinYue Lu, Xiang Cao, Kun Wang, YuHao Wang, Yanni Wu, Zhangping Yan. Lead exposure promotes the inflammation via the circRNA-05280/miR-146a/IRAK1 axis in mammary gland. Ecotoxicology and environmental safety. vol 247. 2022-10-24. PMID:36274319. |
then, from qrt-pcr, western blot and luciferase report, irak1 was found to promote the release of inflammatory factors and tissue apoptosis and could be a specific target of mir-146a. |
2022-10-24 |
2023-08-14 |
mouse |
| Zhenfeng Hu, Lei Zhuo, Yanling Li, Dongpeng Duan, Jing Gu. MicroRNA‑203a‑3p suppresses endothelial cell proliferation and invasion, and promotes apoptosis in hemangioma by inactivating the VEGF‑mediated PI3K/AKT pathway. Experimental and therapeutic medicine. vol 24. issue 5. 2022-10-24. PMID:36277151. |
cell proliferation (by cell counting kit-8 assay), apoptosis (by tunel assay), invasion (by transwell assay) and pi3k/akt signaling (by western blot) were assessed following transfection of these cells. |
2022-10-24 |
2023-08-14 |
human |
| Lu Liu, Yuan Yuan, Yu Zhou, Liangfang Yao, Jinbao Li, Feng Che. The transcription factor KLF14 attenuates LPS-induced acute lung injury by ameliorating apoptosis of alveolar epithelial cells in mice. Molecular immunology. vol 152. 2022-10-24. PMID:36279660. |
in this study, we found that the krüppel-like transcription factor klf14 can suppress the apoptosis of alveolar epithelial cells in a lps-mediated murine acute lung injury model by western blot and tunel assays. |
2022-10-24 |
2023-08-14 |
mouse |
| Zhe Ji, Jian Wang, Shuai Yang, Shengjun Tao, Caiqi Shen, Hanxiao Wei, Qiang Li, Peisheng Ji. Graphene oxide accelerates diabetic wound repair by inhibiting apoptosis of Ad-MSCs via Linc00324/miR-7977/STK4 pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 11. 2022-10-21. PMID:36269304. |
the effects of go on ad-msc apoptosis were explored by flow cytometry, tunel assay, and western blot. |
2022-10-21 |
2023-08-14 |
Not clear |
| Fangfang Zhu, Jie Gao, Fuling Zeng, Yuling Lai, Xiaofeng Ruan, Gaopi Den. Hyperoside protects against cyclophosphamide induced ovarian damage and reduced fertility by suppressing HIF-1α/BNIP3-mediated autophagy. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 156. 2022-10-17. PMID:36252358. |
western blot analysis demonstrate that cy activated key proteins of hif-1α/bnip3-associated autophagy both in vivo and in vitro, while in vivo experiments we also found that 4-hc increased kgn cell apoptosis, damaged mitochondrial membrane potential, and activated autophagic flow. |
2022-10-17 |
2023-08-14 |
mouse |
| Zhuangzhuang Li, Baoyan Ding, Mustafa R K Ali, Lizhen Zhao, Xiaoling Zang, Zhihua L. Dual Effect of Tryptamine on Prostate Cancer Cell Growth Regulation: A Pilot Study. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232383. |
flow cytometry, confocal imaging, and western blot were used to test the apoptosis induced by tryptamine. |
2022-10-14 |
2023-08-14 |
mouse |
| Yuan Li, Qingya Dang, Zhiyi Li, Chuting Han, Yan Yang, Miaoling Li, Pengyun L. Restoration of Mitochondrial Function Is Essential in the Endothelium-Dependent Vasodilation Induced by Acacetin in Hypertensive Rats. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232649. |
mitochondria-dependent apoptosis, the opening of mitochondrial permeability transition pore (mptp) and mitochondrial dynamics proteins were determined by fluorescence activated cell sorting (facs), immunofluorescence staining and western blot. |
2022-10-14 |
2023-08-14 |
rat |
| Vineela Parvathaneni, Rameswari Chilamakuri, Nishant S Kulkarni, Nabeela F Baig, Saurabh Agarwal, Vivek Gupt. Exploring Amodiaquine's Repurposing Potential in Breast Cancer Treatment-Assessment of In-Vitro Efficacy & Mechanism of Action. International journal of molecular sciences. vol 23. issue 19. 2022-10-14. PMID:36232751. |
apoptosis assays, cell cycle analysis, rt-qpcr assays, and western blot studies were performed to determine aq's ability to induce apoptosis, cell cycle changes, gene expression changes, and induction of autophagy marker proteins. |
2022-10-14 |
2023-08-14 |
Not clear |
| Yaling Zhang, Dejian Chen, Daojuan Wang, Lei Wang, Yajing Weng, Hongwei Wang, Xiaoke Wu, Yong Wan. Moderate Aerobic Exercise Regulates Follicular Dysfunction by Initiating Brain-Derived Neurotrophic Factor (BDNF)-Mediated Anti-Apoptotic Signaling Pathways in Polycystic Ovary Syndrome. Journal of clinical medicine. vol 11. issue 19. 2022-10-14. PMID:36233452. |
immunohistochemistry combined with western blot analysis and fluorescence quantitative polymerase chain reaction were used to detect the changes in bdnf-trkb/p75ntr pathway, apoptosis, and inflammatory factors. |
2022-10-14 |
2023-08-14 |
rat |
| Sophie Scholz, Karyn Lewis, Frederik Saulich, Matthias Endres, Wolfgang Boehmerle, Petra Huehnche. Induced pluripotent stem cell-derived brain organoids as potential human model system for chemotherapy induced CNS toxicity. Frontiers in molecular biosciences. vol 9. 2022-10-03. PMID:36188215. |
histological analysis after paclitaxel exposure demonstrated dose dependent apoptosis induction and reduced proliferation in the organoids with further western blot analyses indicating the degradation of neuronal calcium sensor one protein (ncs-1) and activation of caspase-3. |
2022-10-03 |
2023-08-14 |
human |
| Sicheng Chen, Mengjun Bie, Xiaowen Wang, Mengtian Fan, Bin Chen, Qiong Shi, Yingjiu Jian. PGRN exacerbates the progression of non-small cell lung cancer via PI3K/AKT/Bcl-2 antiapoptotic signaling. Genes & diseases. vol 9. issue 6. 2022-09-26. PMID:36157487. |
the proliferation, apoptosis, migration, and invasion of nsclc cells were assessed by the mtt assay, western blot, degree of wound healing, and transwell assays. |
2022-09-26 |
2023-08-14 |
mouse |
| Yao Xue, Yunqian Zhang, Li Chen, Yan Wang, Zhou Lv, Li-Qiao Yang, Siyuan L. Citrulline protects against LPS‑induced acute lung injury by inhibiting ROS/NLRP3‑dependent pyroptosis and apoptosis via the Nrf2 signaling pathway. Experimental and therapeutic medicine. vol 24. issue 4. 2022-09-26. PMID:36160882. |
apoptosis and pyroptosis were detected using western blot analysis and immunofluorescence. |
2022-09-26 |
2023-08-14 |
mouse |
| Sheng Gao, Luyue Bai, Shu Jia, Chunyang Men. Small Extracellular Vesicles of M1-BV2 Microglia Induce Neuronal PC12 Cells Apoptosis via the Competing Endogenous Mechanism of CircRNAs. Genes. vol 13. issue 9. 2022-09-23. PMID:36140770. |
furthermore, western blot and flow cytometry analysis demonstrated that m0-bv2 sevs had no distinct effect on apoptosis of neuronal pc12 cells, while m1-bv2 sevs remarkably increased the apoptosis of neuronal pc12 cells. |
2022-09-23 |
2023-08-14 |
Not clear |
| Yaying Lei, Fangqin Hou, Xiaoyu Wu, Yang Yi, Fan Xu, Qihai Gong, Jianmei Ga. Brucine-Induced Neurotoxicity by Targeting Caspase 3: Involvement of PPARγ/NF-κB/Apoptosis Signaling Pathway. Neurotoxicity research. 2022-09-23. PMID:36151391. |
moreover, brucine also significantly induced neuronal apoptosis and triggered increase in ratio of bax/bcl-2 and level of cleaved caspase 3, as well as its activity as evidenced by tunel staining and western blot. |
2022-09-23 |
2023-08-14 |
Not clear |