| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Haichen Zhang, Tong Chu, Jin Zheng, Yun Teng, Ruilan Ma, Lijuan Zou, Haidong Zha. Sensitization of cervical cancer cells to radiation by the cyclin-dependent kinase inhibitor dinaciclib. Medical oncology (Northwood, London, England). vol 40. issue 2. 2022-12-31. PMID:36586018. |
western blot was performed to detect cell cycle, apoptosis, autophagy, and dna damage-related pathways. |
2022-12-31 |
2023-08-14 |
Not clear |
| Yixin Guo, Bing Han, Ting Yang, Yusi Chen, Yi Yang, Cai Liang, Jiayao Li, Qin Yang, Rujia Xi. [Dithiothreitol promotes apoptosis in rat hepatocytes by inhibiting family with sequence similarity 134 member B (FAM134B)-mediated endoplasmic reticulophagy]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 38. issue 12. 2022-12-30. PMID:36585233. |
the level of proteins related to ers, endoplasmic reticulophagy, mitochondria-endoplasmic reticulum contact sites (mercs), and mitochondrial apoptosis pathway were determined using western blot analysis. |
2022-12-30 |
2023-08-14 |
rat |
| Junliang Ma, Yijun Luo, Yingjie Liu, Cheng Chen, Anping Chen, Lubiao Liang, Wenxiang Wang, Yongxiang Son. Exosome-mediated lnc-ABCA12-3 promotes proliferation and glycolysis but inhibits apoptosis by regulating the toll-like receptor 4/nuclear factor kappa-B signaling pathway in esophageal squamous cell carcinoma. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 27. issue 1. 2022-12-28. PMID:36575934. |
western blot was conducted to identify protein expression levels of mitochondrial apoptosis and toll-like receptor 4 (tlr4)/nuclear factor kappa-b (nf-κb) signaling pathway. |
2022-12-28 |
2023-08-14 |
Not clear |
| Tianyuan Guan, Yining Xiao, Xiaohua Xie, Nan Meng, Qianqian Qi, Jing Xu, Xin Jiang, Zhe Zhang, Zhenjie Teng, Peiyuan L. Dulaglutide Improves Gliosis and Suppresses Apoptosis/Autophagy Through the PI3K/Akt/mTOR Signaling Pathway in Vascular Dementia Rats. Neurochemical research. 2022-12-26. PMID:36571662. |
western blot results showed that dulaglutide reduced vd-induced neuronal apoptosis (bcl2/bax, c-caspase3) and autophagy (p62, lc3b, beclin-1), and upregulated phosphorylation of pi3k/akt/mtor signaling pathway. |
2022-12-26 |
2023-08-14 |
rat |
| Hong Bae Kim, Chu Hui Zeng, Yunlim Kim, Seung Jeong, Song Hee Kim, Jeon Min Kang, Yubeen Park, Dong-Sung Won, Ji Won Kim, Dae Sung Ryu, Bumjin Lim, Jung-Hoon Par. Effects of different applied voltages of irreversible electroporation on prostate cancer in a mouse model. Scientific reports. vol 12. issue 1. 2022-12-26. PMID:36572706. |
the histological, immunohistochemical, and western blot findings all confirmed ire-induced apoptosis in the treatment groups. |
2022-12-26 |
2023-08-14 |
mouse |
| Quan Wang, Zhao Zhang, Xuesong Ga. Effects of ophthalmic surface anesthetic alcaine on the proliferation and apoptosis of human corneal endothelial cells through HIF-1α regulation. Cell and tissue banking. 2022-12-26. PMID:36572744. |
cell apoptosis rate, hif-1α mrna expression, and hif-1α, p/t-jnk and caspase-3 protein levels were detected by flow cytometry, rt-qpcr, and western blot. |
2022-12-26 |
2023-08-14 |
human |
| Rajeev Shrestha, Hyun Ji Lee, Junmo Lim, Pallavi Gurung, Til Bahadur Thapa Magar, Young-Tak Kim, Kija Lee, Seulgi Bae, Yong-Wan Ki. Effect of Photodynamic Therapy with Chlorin e6 on Canine Tumors. Life (Basel, Switzerland). vol 12. issue 12. 2022-12-23. PMID:36556469. |
cell proliferation and apoptosis were detected by the 4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (mtt) assay and western blot assay, respectively. |
2022-12-23 |
2023-08-14 |
mouse |
| Tong Zhang, Yun-Hong Xiu, Hui Xue, Yan-Nan Li, Jing-Long Cao, Wen-Shuang Hou, Jian Liu, Yu-He Cui, Ting Xu, Ying Wang, Cheng-Hao Ji. A Mechanism of Isoorientin-Induced Apoptosis and Migration Inhibition in Gastric Cancer AGS Cells. Pharmaceuticals (Basel, Switzerland). vol 15. issue 12. 2022-12-23. PMID:36558992. |
further analysis by flow cytometry and western blot showed that iso induced apoptosis via a mitochondria-dependent pathway. |
2022-12-23 |
2023-08-14 |
Not clear |
| F A Dain Md Opo, Mohammed Moulay, Ghadeer I Alrefaei, Nouf H Alsubhi, Saleh Alkarim, Mohammed M Rahma. Effect of Co-culturing both placenta-derived mesenchymal stem cells and their condition medium in the cancer cell (HepG2) migration, damage through apoptosis and cell cycle arrest. Saudi journal of biological sciences. vol 30. issue 2. 2022-12-23. PMID:36561333. |
flow cytometry, caspase 9 immunofluorescence, qpcr (detection of bax, bcl-2, and β-catenin genes), western blot, and immunophenotyping revealed that treatment with hpmscs or hpmscs-cm caused hepg2 cell death through apoptosis (detection of caspase 9, caspase 3 protein). |
2022-12-23 |
2023-08-14 |
human |
| Chaoyang Liu, Zehua Liu, Yanyan Fang, Zizhuo Liao, Zhibing Zhang, Xin Yuan, Ting Yu, Yunying Yang, Min Xiong, Xingyu Zhang, Guoxin Zhang, Lanxia Meng, Zhentao Zhan. Exposure to dithiocarbamate fungicide maneb in vitro and in vivo: Neuronal apoptosis and underlying mechanisms. Environment international. vol 171. 2022-12-23. PMID:36563597. |
furthermore, western blot analysis found that the mitochondrial apoptosis pathway (bcl-2, bax, cytochrome c, activated caspase-3) and the pka/creb signaling pathway (pka, pde10a, creb, p-creb) were changed by maneb both in vitro and in vivo. |
2022-12-23 |
2023-08-14 |
mouse |
| Huan Hou, Ying Xu, Meilin Xie, Rong Che. Exploring the potential molecular mechanism of trastuzumab-induced cardiotoxicity based on RNA sequencing and bioinformatics analysis. Biochemical pharmacology. 2022-12-23. PMID:36563885. |
in addition, an increased expressions of bax, caspase-3, ifn-γ and tnf-α and a decreased expression of bcl-2 were observe in western blot, indicating the apoptosis and inflammation levels were increased. |
2022-12-23 |
2023-08-14 |
mouse |
| Xueping Xie, Wenjuan Ma, Guo Li, Yuxi Zhan, Li Quan, Xiaoxiao Ca. Tetrahedral framework nucleic acids alleviate irradiation-induced salivary gland damage. Cell proliferation. 2022-12-14. PMID:36514865. |
the expression of apoptosis proteins and inflammatory cytokines were detected by western blot. |
2022-12-14 |
2023-08-14 |
Not clear |
| Nan Zheng, Shan Liu, Huiting Zeng, Huajun Zhao, Lixu Ji. Molecular Mechanism of Curcumin Derivative on YAP Pathway against Ovarian Cancer. Journal of clinical medicine. vol 11. issue 23. 2022-12-11. PMID:36498794. |
mtt assay was used to detect the effect of wz10 on the proliferation of ovarian cancer ovcar3 cells; annexin v/pi double staining flow cytometry was used to detect the effect of wz10 on cell apoptosis; transwell method was used to detect the effect of wz10 on cell invasiveness; western blot was used to investigate the effect of wz10 mechanisms affecting ovcar3 activity in ovarian cancer in vitro. |
2022-12-11 |
2023-08-14 |
Not clear |
| Xiaoli Huang, Jinlin Wan. miR-1 Mediated AMPK Pathway on Cardiomyocyte Apoptosis in Hypertensive Rats. Cellular and molecular biology (Noisy-le-Grand, France). vol 68. issue 7. 2022-12-10. PMID:36495505. |
flow cytometry was used to detect the cell apoptosis, and real-time pcr and western blot were used to detect the mrna and protein expression of bcl-2. |
2022-12-10 |
2023-08-14 |
rat |
| Xiaoxiao Yan, Haibo Jia, Junbo Zha. LncRNA MEG3 attenuates the malignancy of retinoblastoma cells through inactivating PI3K /Akt/mTOR signaling pathway. Experimental eye research. 2022-12-08. PMID:36476400. |
transfected rb cells were assessed for proliferation, apoptosis, migration ability, expression levels of important genes in the pi3k/akt/mtor signaling pathway using qrt-pcr and western blot analysis. |
2022-12-08 |
2023-08-14 |
mouse |
| Jiang Liu, LiJun Ren, HaoWen Wang, Zuowei L. Isoquercitrin Induces Endoplasmic Reticulum Stress and Immunogenic Cell Death in Gastric Cancer Cells. Biochemical genetics. 2022-12-08. PMID:36480095. |
the effect of isoquercitrin on gc cell lines (ags and hgc-27) was evaluated using cell counting kit-8 assays, colony formation assays, annexin v/pi apoptosis detection kit, western blot analysis, jc-1 staining, immunofluorescence assays, and enzyme-linked immunosorbent assay. |
2022-12-08 |
2023-08-14 |
Not clear |
| Jianyi Huang, Jinshu Fang, Xiao Xu, Xueshen Qian, Xia Zhan. SETD1A promotes the proliferation and glycolysis of nasopharyngeal carcinoma cells by activating the PI3K/Akt pathway. Open medicine (Warsaw, Poland). vol 17. issue 1. 2022-12-07. PMID:36475064. |
the assay of glucose uptake, lactate release, atp level, western blot, cell proliferation, and cellular apoptosis analysis were performed to investigate the potential mechanism of setd1a regulation in nasopharyngeal carcinoma. |
2022-12-07 |
2023-08-14 |
Not clear |
| Yuan Luo, Pu Chen, Li-Ping Yang, Xiao-Hua Dua. [Effect of ethanol extract of Gastrodiae Rhizoma on mitochondrial dysfunction in cerebral ischemia-reperfusion injury]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 20. 2022-12-06. PMID:36471974. |
tunel staining was used to observe the apoptosis of brain tissues in each group, and western blot was used to detect the expression of b-cell lymphoma 2(bcl-2) and bcl-2-associated x protein(bax) in brain tissues. |
2022-12-06 |
2023-08-14 |
rat |
| Han Wang, Yilan Wu, Xiaoyan Li. Crizotinib loaded polydopamine-polylactide-TPGS nanoparticles in targeted therapy for non-small cell lung cancer. Medical oncology (Northwood, London, England). vol 40. issue 1. 2022-12-02. PMID:36459216. |
tunel assay and western blot were respectively applied for the determination of cell apoptosis and apoptosis-related protein expression, while liver function-related index expression detection and liver histopathological detection were used to evaluate the hepatotoxicity of czt/pd-pt nps. |
2022-12-02 |
2023-08-14 |
Not clear |
| Shuancheng Zhang, Yucong Ma, Qianqian Zuo, Mengrui Liu, Zhifang Yu, Ying Sun, Cuimiao Song, Hongyan Sun, Guimin Hao, Bulang Gao, Huilan Du, Jingwei Che. Repeated controlled ovarian stimulation-induced ovarian and uterine damage in mice through the PI3K/AKT signaling pathway. Human cell. 2022-11-28. PMID:36441500. |
the morphology of the ovary and endometrium, ovarian apoptosis, and expressions of the vascular endothelial growth factor (vegf), leukemia inhibitory factor (lif), pi3k, akt, bax, and bcl-2 in the ovarian and uterine tissues were tested by hematoxylin-eosin (he) staining, immunohistochemistry, and western blot. |
2022-11-28 |
2023-08-14 |
mouse |