| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yunqi Zhao, Ying Wang, Zimeng Ling, Yaxing Xue, Deji Luan, Jian Kang, Yong Zhang, Fusheng Qua. Low-density small extracellular vesicles in bovine follicular fluid carrying let-7i target FASLG to inhibit granulosa cells apoptosis. Theriogenology. vol 199. 2023-01-30. PMID:36716593. |
flow cytometry, quantitative reverse transcription pcr (rt-qpcr), western blot, and other methods were used to detect the effect of ld-sevs on follicular granulosa cell apoptosis. |
2023-01-30 |
2023-08-14 |
cattle |
| Xin Zhu, Mei Yang, Liu Yan. Isoflurane Postconditioning Alleviates Ischemic Neuronal Injury via MiR-384-5p Regulated Autophagy. Neuroscience. 2023-01-27. PMID:36707017. |
tunel staining and western blot results confirmed that isoflurane post-conditioning could regulate mir-384-5p and inhibit apoptosis. |
2023-01-27 |
2023-08-14 |
mouse |
| Yalong Gao, Hejun Zhang, Jiwei Wang, Fanjian Li, Xiaotian Li, Tuo Li, Cong Wang, Lei Li, Ruilong Peng, Li Liu, Weiyun Cui, Shu Zhang, Jianning Zhan. Annexin A5 ameliorates traumatic brain injury-induced neuroinflammation and neuronal ferroptosis by modulating the NF-ĸB/HMGB1 and Nrf2/HO-1 pathways. International immunopharmacology. vol 114. 2023-01-26. PMID:36700781. |
two days after the traumatic brain injury, we collected injured cortex tissues for western blot, perl's staining, apoptosis staining, nissl staining, immunofluorescence/immunohistochemistry, and enzyme-linked immunosorbent assay. |
2023-01-26 |
2023-08-14 |
mouse |
| Wenqiang Xu, Xiaofeng Liu, Wenqing Qu, Xin Wang, Hao Su, Wenliang Li, Yiheng Chen. Exosomes derived from fibrinogen-like protein 1-overexpressing bone marrow-derived mesenchymal stem cells ameliorates rheumatoid arthritis. Bioengineered. vol 13. issue 6. 2023-01-25. PMID:36694465. |
cell viability, apoptosis, inflammation factors, and protein levels were detected by cck-8, flow cytometry, enzyme-linked immunosorbent assay and western blot, respectively. |
2023-01-25 |
2023-08-14 |
rat |
| Wei Dai, Yong Gang Dai, Dong Feng Ren, Da Wei Zh. Dieckol, a natural polyphenolic drug, inhibits the proliferation and migration of colon cancer cells by inhibiting PI3K, AKT, and mTOR phosphorylation. Journal of biochemical and molecular toxicology. 2023-01-23. PMID:36683349. |
protein expression of cell survival, cell cycle, proliferation, and apoptosis protein was evaluated by western blot analysis. |
2023-01-23 |
2023-08-14 |
Not clear |
| Yi Wei, Lei Sun, Chao Liu, Lujia L. Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis. Naunyn-Schmiedeberg's archives of pharmacology. 2023-01-23. PMID:36688958. |
cell apoptosis was estimated by western blot and tunel staining. |
2023-01-23 |
2023-08-14 |
mouse |
| Ya-Hui Chen, Jyun-Xue Wu, Shun-Fa Yang, Yi-Hsuan Hsia. Synergistic Combination of Luteolin and Asiatic Acid on Cervical Cancer In Vitro and In Vivo. Cancers. vol 15. issue 2. 2023-01-21. PMID:36672499. |
lut combined with asa caused apoptosis induction and sub-g1-phase arrest in caski and hela cells, as confirmed by flow cytometry, mitoros analysis, antioxidant activity measurement and western blot assay. |
2023-01-21 |
2023-08-14 |
Not clear |
| Weilin Song, George Hoppe, Demiana Hanna, Tara M DeSilva, Jonathan E Sear. Hyperoxia Induced Hypomyelination. Biomedicines. vol 11. issue 1. 2023-01-21. PMID:36672545. |
corpus callosal sections were probed myelin immunofluorescence, tested for myelin basic protein concentration by western blot, and both glial fibrillary acidic protein levels and apoptosis quantified. |
2023-01-21 |
2023-08-14 |
mouse |
| Wei Sun, Nai-Dan Zhang, Tong Zhang, Yan-Nan Li, Hui Xue, Jing-Long Cao, Wen-Shuang Hou, Jian Liu, Ying Wang, Cheng-Hao Ji. Cyanidin-3-O-Glucoside Induces the Apoptosis of Human Gastric Cancer MKN-45 Cells through ROS-Mediated Signaling Pathways. Molecules (Basel, Switzerland). vol 28. issue 2. 2023-01-21. PMID:36677726. |
western blot and flow cytometry results showed that c3g regulated the reduction of mitochondrial membrane potential and arrested the cell cycle in the g2/m phase through the akt signaling pathway, causing the cells to undergo apoptosis. |
2023-01-21 |
2023-08-14 |
human |
| Jun Li, Song-He Wang, Yang-Ting Liu, Qin Zhang, Guang-Zhou Zho. Inhibition of autophagic flux by the curcumin analog EF-24 and its antiproliferative effect on MCF-7 cancer cells. Journal of biochemical and molecular toxicology. 2023-01-12. PMID:36633067. |
ef-24 could also induce apoptosis of mcf-7 cells as determined by hoechst 33342 staining, flow cytometry analysis, and western blot analysis. |
2023-01-12 |
2023-08-14 |
Not clear |
| Tingwen Cai, Hantao Ye, Hongyi Jiang, Chihao Lin, Chao Lou, Weidan Wang, Zijian Yan, Xinghe Xue, Xiaoyun Pan, Jian Li. Stevioside targets the NF-κB and MAPK pathways for inhibiting inflammation and apoptosis of chondrocytes and ameliorates osteoarthritis in vivo. International immunopharmacology. vol 115. 2023-01-11. PMID:36630751. |
on the basis of western blot, we have observed the protein expressions of cartilage matrix metabolism, inflammatory factors, and apoptosis of chondrocytes. |
2023-01-11 |
2023-08-14 |
mouse |
| Jingtao Luo, Yun Wang, Lingkun Zhao, Chunli Wang, Ze Zhan. Anti-Anaplastic Thyroid Cancer (ATC) Effects and Mechanisms of PLX3397 (Pexidartinib), a Multi-Targeted Tyrosine Kinase Inhibitor (TKI). Cancers. vol 15. issue 1. 2023-01-08. PMID:36612171. |
western blot assays were conducted to evaluate changes in key molecules related to apoptosis and er stress. |
2023-01-08 |
2023-08-14 |
Not clear |
| Li-Chun Liu, Zih-Syuan Wu, Jia-Lin Chen, Zhi-Fu Wu, Hou-Chuan Lai, Yi-Hsuan Huan. Mitochondrial Dysfunction Involved in the Cytotoxicity of Tramadol in Human Endometrial Carcinoma Cells. International journal of molecular sciences. vol 24. issue 1. 2023-01-08. PMID:36613541. |
colony formation, brdu, cell cycle profiles, apoptosis, ros, and western blot analyses were used to study the response of endometrial cancer cells to tramadol. |
2023-01-08 |
2023-08-14 |
human |
| Xue-Jiao Wei, Ya-Xin Liu, Hui-Ming Huang, Li-Shan Ouyang, Jin-Xin Xie, Long-Yan Wang, Dong-Xiao Liu, Peng-Fei Tu, Zhong-Dong H. [Anti-tumor effect of Huaier extract supernatant on human gastric cancer HGC-27 and MGC-803 cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 23. 2023-01-06. PMID:36604892. |
western blot was used to investigate the regulatory effect of hes on the expression levels of proteins related to apoptosis, epithelial-mesenchymal transition(emt), and signaling pathways in human gastric cancer hgc-27 and mgc-803 cells. |
2023-01-06 |
2023-08-14 |
human |
| Shaolei Chen, Lin Zhu, Jun L. Fucoxanthin ameliorates oxidative injury and inflammation of human bronchial epithelial cells induced by cigarette smoke extract via the PPARγ/NF‑κB signaling pathway. Experimental and therapeutic medicine. vol 25. issue 1. 2023-01-06. PMID:36605523. |
additionally, a tunel assay and western blot analysis were performed to assess the cell apoptosis rate. |
2023-01-06 |
2023-08-14 |
human |
| Su-Ying Wen, Ayaz Ali, I-Chieh Huang, Jian-Sheng Liu, Po-Yuan Chen, Vijaya Padma Viswanadha, Chih-Yang Huang, Wei-Wen Ku. Doxorubicin induced ROS-dependent HIF1α activation mediates blockage of IGF1R survival signaling by IGFBP3 promotes cardiac apoptosis. Aging. vol 14. 2023-01-05. PMID:36602546. |
finally, western blot data revealed that ros scavenger reversed dox-induced cardiac apoptosis, increased levels of hif1a and secreted igfbp3, and decreased igf1 survival signaling and phd expression. |
2023-01-05 |
2023-08-14 |
rat |
| Xuan Qi, Ronghua Wang, Lu Jin, Yu Tian, Hongtao Jin, Yuxiang Han, Chao Sun, Meng Ding, Huifang Gu. MiR-223-3p aggravates ocular inflammation in Sjögren's syndrome. Endocrine, metabolic & immune disorders drug targets. 2023-01-04. PMID:36597599. |
cck-8, flow cytometry, and western blot assay were exploited to determine cell viability, apoptosis, and apoptosis-related protein levels. |
2023-01-04 |
2023-08-14 |
Not clear |
| Jin Song, Xiaolong Xu, Shasha He, Ning Wang, Yunjing Bai, Zhaoxia Chen, Bo Li, Shengsheng Zhan. Myristicin Suppresses Gastric Cancer Growth via Targeting the EGFR/ERK Signaling Pathway. Current molecular pharmacology. 2023-01-04. PMID:36597605. |
the levels of proteins associated with cell cycle, apoptosis, endoplasmic reticulum (er) stress, and egfr/erk signaling pathway were detected by western blot. |
2023-01-04 |
2023-08-14 |
human |
| Beom-Goo Kang, Madhuri Shende, Gozde Inci, Soo-Hyun Park, Jun-Sub Jung, Set Byeol Kim, Jeong Hoon Kim, Young Won Mo, Ji-Hyeon Seo, Jing-Hui Feng, Sung-Chan Kim, Soon Sung Lim, Hong-Won Suh, Jae-Yong Le. Combination of metformin/efavirenz/fluoxetine exhibits profound anticancer activity via a cancer cell-specific ROS amplification. Cancer biology & therapy. vol 24. issue 1. 2023-01-02. PMID:36588385. |
western blot analysis indicated that dna damage, apoptosis, autophagy, and necroptosis-realated factors increased in m + e + f-treated hct116 cells. |
2023-01-02 |
2023-08-14 |
mouse |
| Na Qu, Junsheng Qu, Na Huang, Kexin Zhang, Tongtong Ye, Junfeng Shi, Bing Chen, Chengxia Kan, Jingwen Zhang, Fang Han, Ningning Hou, Xiaodong Sun, Ruiyan Pa. Calycosin induces autophagy and apoptosis Frontiers in pharmacology. vol 13. 2023-01-02. PMID:36588732. |
apoptosis and autophagy-related markers or proteins were measured by qrt-pcr or western blot. |
2023-01-02 |
2023-08-14 |
human |