| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laura N Milla, Ingrid S Cogno, Matías E Rodríguez, Francisco Sanz-Rodríguez, Alicia Zamarrón, Yolanda Gilaberte, Elisa Carrasco, Viviana A Rivarola, Angeles Juarran. Isolation and characterization of squamous carcinoma cells resistant to photodynamic therapy. Journal of cellular biochemistry. vol 112. issue 9. 2011-12-07. PMID:21503960. |
in parental and resistant cells there were analyzed the cell morphology (toluidine blue), the intracellular ppix content (flow cytometry) and its localization (fluorescence microscopy), the capacity of closing wounds (scratch wound assay), the expression of cell-cell adhesion proteins (e-cadherin and β-catenin), cell-substrate adhesion proteins (β1-integrin, vinculin and phospho-fak), cytoskeleton proteins (α-tubulin and f-actin) and the inhibitor of apoptosis protein survivin, in the activated form as phospho-survivin (indirect immunofluorescence and western blot). |
2011-12-07 |
2023-08-12 |
Not clear |
| Binbin Liu, Pengfei Yang, Yuanchao Ye, Yan Zhou, Lingzhi Li, Shin-Ichi Tashiro, Satoshi Onodera, Takashi Ikejim. Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells. Free radical research. vol 45. issue 7. 2011-12-06. PMID:21568648. |
subsequent morphologic observation, flow cytometric analysis and western blot analysis indicated that treatment with snp significantly induced apoptosis in pc12 cells. |
2011-12-06 |
2023-08-12 |
mouse |
| Ming-Feng Wu, Ping-Chia Li, Chin-Chiu Chen, Su-Shin Ye, Chiang-Ting Chien, Chia-Cherng Y. Cordyceps sobolifera extract ameliorates lipopolysaccharide-induced renal dysfunction in the rat. The American journal of Chinese medicine. vol 39. issue 3. 2011-12-06. PMID:21598419. |
we further examined the effects of cs supplement on renal tubular oxidative stress, endoplasmic reticulum stress, apoptosis and autophagy by western blot analysis. |
2011-12-06 |
2023-08-12 |
rat |
| Gang Cui, Zhen Li, Bai Shao, Li Zhao, Yanfeng Zhou, Ting Lu, Junxiang Wang, Xioayong Shi, Jinjin Wang, Gang Zuo, Weiwei Zhu, Aiguo She. Clinical and biological significance of nemo-like kinase expression in glioma. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 18. issue 2. 2011-12-05. PMID:21177110. |
we also analyzed the effect of overexpression of nlk on cell apoptosis using a cell counting kit and western blot analysis. |
2011-12-05 |
2023-08-12 |
human |
| Majid Mahdavi, Jamshid Davoodi, Mohammad Reza Zali, Alireza Foroumad. Concomitant activation of caspase-9 and down-regulation of IAP proteins as a mechanism of apoptotic death in HepG2, T47D and HCT-116 cells upon exposure to a derivative from 4-aryl-4H-chromenes family. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 65. issue 3. 2011-12-05. PMID:21565459. |
furthermore, western blot analysis revealed that treatment with 3-nc down-regulated the expression of inhibitor of apoptosis proteins, ciap2, xiap and survivin in cell line dependent manner. |
2011-12-05 |
2023-08-12 |
human |
| Gangming Cai, Mengjun Jiang, Yaoyuan Zhou, Xiaobo Gu, Bo Zhang, Meifen Zou, Xingqin Zhou, Jiandong Bao, Guoxian Cao, Rongjun Zhan. Generation of a liver targeting fusion interferon and its bioactivity analysis in vitro. Die Pharmazie. vol 66. issue 10. 2011-12-02. PMID:22026157. |
hochest33342 and propidium iodide (pi) double staining and western blot analysis of bcl-2/bax were also performed to evaluate cell lethality and apoptosis. |
2011-12-02 |
2023-08-12 |
Not clear |
| Reiko Ikeda, Masaki Kurosawa, Takazumi Okabayashi, Ayako Takei, Masamichi Yoshiwara, Tadashi Kumakura, Norio Sakai, Osamu Funatsu, Akinori Morita, Masahiko Ikekita, Yumi Nakaike, Takeo Konakahar. 3-(3-Phenoxybenzyl)amino-β-carboline: a novel antitumor drug targeting α-tubulin. Bioorganic & medicinal chemistry letters. vol 21. issue 16. 2011-11-22. PMID:21752645. |
to verify 2h-induced cell death types, we observed the chromatin condensation, the dna fragmentation and activated caspase-3 using hoechst 33342, agarose electrophoresis and western blot, and suggesting 2h-induced cell death type was apoptosis. |
2011-11-22 |
2023-08-12 |
Not clear |
| Francesco Fabbri, Wainer Zoli, Silvia Carloni, Paola Ulivi, Chiara Arienti, Giovanni Brigliadori, Marco Montanari, Anna Tesei, Rosella Silvestrini, Dino Amador. Activity of different anthracycline formulations in hormone-refractory prostate cancer cell lines: role of Golgi apparatus. Journal of cellular physiology. vol 226. issue 11. 2011-11-15. PMID:21302303. |
drug activity and incorporation, apoptosis, and expression of cell death-related markers were evaluated by srb test, cytofluorimetric assays, and western blot, respectively. |
2011-11-15 |
2023-08-12 |
Not clear |
| Weicheng Hu, Ting Shen, Myeong-Hyeon Wan. Cell cycle arrest and apoptosis induced by methyl 3,5-dicaffeoyl quinate in human colon cancer cells: Involvement of the PI3K/Akt and MAP kinase pathways. Chemico-biological interactions. vol 194. issue 1. 2011-11-15. PMID:21872580. |
western blot analysis showed that apoptosis was dependent on caspase-3 activity. |
2011-11-15 |
2023-08-12 |
human |
| C Quintavalle, M Brenca, F De Micco, D Fiore, S Romano, M F Romano, F Apone, A Bianco, M A Zabatta, G Troncone, C Briguori, G Condorell. In vivo and in vitro assessment of pathways involved in contrast media-induced renal cells apoptosis. Cell death & disease. vol 2. 2011-11-01. PMID:21562587. |
by analyzing urine samples obtained from patients who experienced contrast-induced acute kidney injury (ci-aki), we verified, by western blot and immunohistochemistry, that cm induces tubular renal cells apoptosis. |
2011-11-01 |
2023-08-12 |
Not clear |
| Louisa G Mahaira, Chrisiida Tsimplouli, Nikos Sakellaridis, Konstantinos Alevizopoulos, Costas Demetzos, Zhiyong Han, Panayotis Pantazis, Konstantinos Dima. The labdane diterpene sclareol (labd-14-ene-8, 13-diol) induces apoptosis in human tumor cell lines and suppression of tumor growth in vivo via a p53-independent mechanism of action. European journal of pharmacology. vol 666. issue 1-3. 2011-10-25. PMID:21620827. |
sclareol-induced cell cycle arrest and apoptosis were assessed by flow cytometry and western blot analyses. |
2011-10-25 |
2023-08-12 |
mouse |
| Qun Cheng, Weipin Dong, Lei Qian, Jingcheng Wu, Yongde Pen. Visfatin inhibits apoptosis of pancreatic β-cell line, MIN6, via the mitogen-activated protein kinase/phosphoinositide 3-kinase pathway. Journal of molecular endocrinology. vol 47. issue 1. 2011-10-17. PMID:21471274. |
an 1-(4,5-dimethylthiazol-2-yl)-3,5-diphenylformazan assay was used to detect cell proliferation, v-fitc/propidium iodide staining was used to measure cell apoptosis and necrosis, and western blot analysis was used to detect the expression of proapoptotic proteins. |
2011-10-17 |
2023-08-12 |
mouse |
| Tatsuya Hayama, Keiichi Tabata, Taketo Uchiyama, Yasuo Fujimoto, Takashi Suzuk. Ferrearin C induces apoptosis via heme oxygenase-1 (HO-1) induction in neuroblastoma. Journal of natural medicines. vol 65. issue 3-4. 2011-10-14. PMID:21327520. |
in a western blot analysis, ferrearin c (1) increased the level of bax and reduced the level of survivin, indicating the activation of the mitochondrial pathway of apoptosis. |
2011-10-14 |
2023-08-12 |
human |
| Rong Hu, Rong Zhang, Ying-Chun Li, Kun Yao, Ying Yang, Si-Yuan Hou, Wei Yang, Zhuo-Gang Li. [Effect of bortezomib on sensitization of HL-60 cells to TRAIL]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 3. 2011-10-13. PMID:20561413. |
the cell apoptosis was determined by flow cytometry with annexin v/pi double staining and the expression of caspase-8 was detected by western blot. |
2011-10-13 |
2023-08-12 |
Not clear |
| Yang Yang, Hong-Juan Dong, Guang-Xun Gao, Yi-Wei Wang, Hong-Tao Gu, Mi-Mi Shu, Hua-Feng Zhu, Xie-Qun Che. [Effects of xbp-1 gene silencing on bortezomib-induced apoptosis in human multiple myeloma cells]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 5. 2011-10-13. PMID:21129256. |
after xbp-1 gene expression was interfered by small hairpin rna, the cell apoptosis was assayed by flow cytometry with annexin v-fitc/pi staining, and the expression level of xbp-1 protein was detected by western blot. |
2011-10-13 |
2023-08-12 |
human |
| Hui Zhao, Qing-Xian Bai, Gao-Sheng Huang, Li-Jie Yang, Peng Yue, Xiao-Yan Zhang, Lu Wang, Lin-Ni Fan, Jin Zh. [Bortezomib depresses osteoblast apoptosis induced by mouse myeloma cells]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 5. 2011-10-13. PMID:21129258. |
the inhibitory effect of bzb on proliferation of mc-3t3e1 assayed by modified mtt method, the apoptosis of mc-3t3e1 cells was determined by flow cytometry with annexin v/pi staining, the expressions of osteoblast markers, runx2/cbfa1, osteocalcin (ocn) and osterix (osx) in mc-3t3e1 treated with bzb were detected by rt-pcr and western blot respectively. |
2011-10-13 |
2023-08-12 |
mouse |
| Syamantak Majumder, Jamila H Siamwala, Sundaramoorthy Srinivasan, Swaraj Sinha, Sree Rama Chaitanya Sridhara, Gowrishankar Soundararajan, Himabindu Reddy Seerapu, Suvro Chatterje. Simulated microgravity promoted differentiation of bipotential murine oval liver stem cells by modulating BMP4/Notch1 signaling. Journal of cellular biochemistry. vol 112. issue 7. 2011-10-12. PMID:21433062. |
proliferation, apoptosis, immunofluorescence assays and western blot analysis were carried out to study the effects of simulated microgravity on liver stem cells. |
2011-10-12 |
2023-08-12 |
Not clear |
| Bin Chu, Ying Zhang, Hong-Xing Liu, Yan-Xia Bai, Xing-Guo Zuo, Min-Qiu Lu, Meng-Qing Wu, Lei Shi, Lei Liu, Ping Zh. [Induction of apoptosis of leukemic tumor cells in mouse model with G-quadruplex ligand Tel03]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 1. 2011-10-06. PMID:20137119. |
cell apoptosis was detected with tunel assay and the expression levels of bcl-2 and bax were detected by western blot. |
2011-10-06 |
2023-08-12 |
mouse |
| Bin Wu, Xu Wang, Hui-Han Wang, Hong-Tao Wang, Wei Yang, Zuo-Fei Chi, Zhuo-Gang Li. [Apoptosis of jurkat cells induced by ursolic acid and its mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 1. 2011-10-06. PMID:20137120. |
the cytotoxic effect of different concentration ua on jurkat cells and inhibitory effect of caspase-9 inhibitor on cytotoxicity of ua were assayed by using wst-8 method; the jurkat cells treated with 20 or 40 micromol/l ua for 2 or 4 hours were collected and were stained by annexin/pi, then the apoptosis rate of jurkat cells was detected by flow cytometry; the jurkat cells in logarithmic growth phase were collected after treatment with different concentrations of ua for different times, the cell protein was extracted, then the activation of caspase-9, -3 and cytochrome c as well as phosphorylation level of akt were determined by western blot. |
2011-10-06 |
2023-08-12 |
Not clear |
| Fei Wang, Bao-An Chen, Jian Cheng, Wen-Lin Xu, Xue-Mei Wang, Jia-Hua Ding, Chong Gao, Yun-Yu Sun, Jun Wang, Gang Zhao, Wen Bao, Hui-Hui Song, Feng Gao, Wei Zhang, Guo-Hua Xia, Xiao-Ping Pei, Wei-Wei Wu, Li Yin, Xue-Yun Sha. [Effects of hypoxia-inducible factor inhibitor on expression of HIF-1alpha and VEGF and induction of apoptosis in leukemic cell lines]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 1. 2011-10-06. PMID:20137122. |
after treatment of u937 cell with 4 micromol/l yc-1, cell apoptosis was assayed by dapi staining under fluorescent microscope and flow cytometry with annexin v-fitc/pi staining; the expression levels of hif-1alpha mrna and vegf mrna were measured with rt-pcr; the expression levels of hif-1alpha, vegf, bax, bcl-2 and caspase-3 proteins were measured by western blot. |
2011-10-06 |
2023-08-12 |
Not clear |