| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yun-Mi Jeong, Hailan Li, Su Yeon Kim, Woo-Jae Park, Hye-Young Yun, Kwang Jin Baek, Nyoun Soo Kwon, Ji Hoon Jeong, Soon Chul Myung, Dong-Seok Ki. Photo-activated 5-hydroxyindole-3-acetic acid induces apoptosis of prostate and bladder cancer cells. Journal of photochemistry and photobiology. B, Biology. vol 103. issue 1. 2011-07-29. PMID:21310627. |
to elucidate the death mechanism by 5-hiaa(uvb), we examined the signal transduction pathways related to apoptosis using western blot analysis. |
2011-07-29 |
2023-08-12 |
human |
| Yan-Wei Ye, Jiang-Hong Wu, Chun-Meng Wang, Ye Zhou, Chun-Yan Du, Bi-Qiang Zheng, Xi Cao, Xiao-Yan Zhou, Meng-Hong Sun, Ying-Qiang Sh. Sox17 regulates proliferation and cell cycle during gastric cancer progression. Cancer letters. vol 307. issue 2. 2011-07-28. PMID:21514720. |
furthermore, a series of function assays, utilizing small interfering rna (sirna)-mediated knockdown of sox17 expression in mkn45 gastric cancer cells, have been performed in this study, including proliferation assay, clonogenic assay, cell-cycle evaluation, apoptosis detection as well as western blot assay. |
2011-07-28 |
2023-08-12 |
Not clear |
| Ping Liu, Lei Zhao, Shu-Ling Zhang, Ji-Zhou Xian. Modified Wendan Decoction can Attenuate Neurotoxic Action Associated with Alzheimer's Disease. Evidence-based complementary and alternative medicine : eCAM. vol 6. issue 3. 2011-07-14. PMID:18955245. |
cell mortality and survival rate was examined by trypan blue stain assay and mtt method and caspase-3 expression was detected by western blot, while cell apoptosis was examined by flow cytometry. |
2011-07-14 |
2023-08-12 |
rat |
| Elona Rrapo, Yuyan Zhu, Jun Tian, Huayan Hou, Adam Smith, Francisco Fernandez, Jun Tan, Brian Giunt. Green Tea-EGCG reduces GFAP associated neuronal loss in HIV-1 Tat transgenic mice. American journal of translational research. vol 1. issue 1. 2011-07-14. PMID:19966940. |
this was accompanied by a mild reduction in activated microglia by iba-1 staining and significant reduction in neuronal loss through apoptosis as demonstrated by map2 staining and western blot analysis respectively. |
2011-07-14 |
2023-08-12 |
mouse |
| Wibisono Hartojo, Amy L Silvers, Dafydd G Thomas, Christopher W Seder, Lin Lin, Hyma Rao, Zhuwen Wang, Joel K Greenson, Thomas J Giordano, Mark B Orringer, Alnawaz Rehemtulla, Mahaveer S Bhojani, David G Beer, Andrew C Chan. Curcumin promotes apoptosis, increases chemosensitivity, and inhibits nuclear factor kappaB in esophageal adenocarcinoma. Translational oncology. vol 3. issue 2. 2011-07-14. PMID:20360934. |
curcumin alone inhibited nf-kappab activity and induced apoptosis in both flo-1 and oe33 eac cell lines as determined by western blot analysis, nf-kappab reporter assays, and caspase-glo 3/7 assays. |
2011-07-14 |
2023-08-12 |
Not clear |
| Siddig Ibrahim Abdelwahab, Syam Mohan, Manal Mohamed Elhassan, Nabil Al-Mekhlafi, Abdelbasit Adam Mariod, Ahmad Bustamam Abdul, Mahmood Ameen Abdulla, Khalid M Alkharf. Antiapoptotic and Antioxidant Properties of Orthosiphon stamineus Benth (Cat's Whiskers): Intervention in the Bcl-2-Mediated Apoptotic Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2011. 2011-07-14. PMID:21234328. |
the role of os against hydrogen peroxide induced apoptosis on mda-m231 epithelial cells was examined using mtt assay, phase contrast microscope, colorimetric assay of caspase-3, western blot and quantitative real-time pcr. |
2011-07-14 |
2023-08-12 |
cat |
| Zhen-Chuan Shang, Ting-Ting Song, Yang-Tang Hou, Li Fu, Tao Deng, Hai Yi, Tao Zhang, Bing-Zhong Su. [Role of mitochondria pathway in signal transduction of chronic myeloid leukemia]. Zhongguo shi yan xue ye xue za zhi. vol 17. issue 2. 2011-07-12. PMID:19379550. |
after bcr3/abl2 antisense oligodeoxynucleotide (aso) was introduced into cml cell line k562 cells by liposomal transfection, the cell viability was detected by mtt assay, the cell apoptosis was determined by flow cytometry (fcm), the mitochondrial membrane potential (deltapsi) was labeled by rhodamine 123 and examined by fcm, and the expression of mitochondrial apoptosis signal transduction pathway related proteins cytochrome c was analyzed by western blot. |
2011-07-12 |
2023-08-12 |
Not clear |
| Zhong-Hua DU, Ke-Wei Ma, Guo-Zi Yang, Wei L. [Mechanism of leukemia cell apoptosis induced by sodium butyrate activating TRAIL pathway]. Zhongguo shi yan xue ye xue za zhi. vol 17. issue 2. 2011-07-12. PMID:19379558. |
flow cytometry was used to detect the apoptosis of leukemia cell lines nb4, u937 and jurkat, and the changes of mrna and protein expressions of trail, dr4 and dr5 were detected by western blot and rt-pcr respectively. |
2011-07-12 |
2023-08-12 |
Not clear |
| Jie Yuan, Zhenjian He, Jueheng Wu, Yongcheng Lin, Xun Zh. A novel adriamycin analogue derived from marine microbes induces apoptosis by blocking Akt activation in human breast cancer cells. Molecular medicine reports. vol 4. issue 2. 2011-07-12. PMID:21468561. |
apoptosis induced by 1403p-3 was detected, as indicated by annexin v-fitc/pi staining, elevated activated caspase-8 and -9, and cleavaged parp determined by western blot analysis. |
2011-07-12 |
2023-08-12 |
human |
| Jingtao Tong, Ganfeng Xie, Jinxia He, Jianjun Li, Feng Pan, Houjie Lian. Synergistic antitumor effect of dichloroacetate in combination with 5-fluorouracil in colorectal cancer. Journal of biomedicine & biotechnology. vol 2011. 2011-07-05. PMID:21403907. |
cell cycle and apoptosis were measured by flow cytometry, and the expression of apoptosis-related molecules was assessed by western blot. |
2011-07-05 |
2023-08-12 |
human |
| D Kumar, F Schatz, R M Moore, B M Mercer, N Rangaswamy, J M Mansour, C J Lockwood, J J Moor. The effects of thrombin and cytokines upon the biomechanics and remodeling of isolated amnion membrane, in vitro. Placenta. vol 32. issue 3. 2011-07-01. PMID:21300402. |
biochemical evidence of remodeling and apoptosis; immunoreactive matrix metalloproteinase 9 (mmp9), tissue inhibitor of matrix metalloproteinase 3 (timp3) and cleaved poly (adp-ribose) polymerase (c-parp) levels in tissue extracts, were determined by western blot and densitometry. |
2011-07-01 |
2023-08-12 |
Not clear |
| Zhiwei Chen, Xiaomin Niu, Ziming Li, Yongfeng Yu, Xiangyun Ye, Shun Lu, Zhen Che. Effect of ubiquitin carboxy-terminal hydrolase 37 on apoptotic in A549 cells. Cell biochemistry and function. vol 29. issue 2. 2011-06-20. PMID:21287580. |
using mtt assay, western blot, hoechst 33342 staining assay and flow cytometry, we found that silencing of uch37 in a549 cells induced apoptosis. |
2011-06-20 |
2023-08-12 |
Not clear |
| Olesya Chornoguz, Lydia Grmai, Pratima Sinha, Konstantin A Artemenko, Roman A Zubarev, Suzanne Ostrand-Rosenber. Proteomic pathway analysis reveals inflammation increases myeloid-derived suppressor cell resistance to apoptosis. Molecular & cellular proteomics : MCP. vol 10. issue 3. 2011-06-16. PMID:21191032. |
using activated caspase 3 and caspase 8 as indicators of apoptosis, flow cytometry, confocal microscopy, and western blot analyses demonstrated that inflammation-induced mdsc treated with a fas agonist contain lower levels of activated caspases, suggesting that inflammation enhances resistance to fas-mediated apoptosis. |
2011-06-16 |
2023-08-12 |
Not clear |
| Ramamurthi Vidya Priyadarsini, Govindarajah Vinothini, Ramalingam Senthil Murugan, Palrasu Manikandan, Siddavaram Nagin. The flavonoid quercetin modulates the hallmark capabilities of hamster buccal pouch tumors. Nutrition and cancer. vol 63. issue 2. 2011-06-14. PMID:21294050. |
we analyzed the expression of markers associated with cell proliferation and survival (pcna, p21, p53, cyclin d1, gst-p), apoptosis (fas, fas-l, bcl-2 family proteins, cytochrome-c, apaf-1, caspases, parp, survivin, cflip, api1), invasion (mmps, timp-2, reck), angiogenesis (plgf, vegf, vegf receptors, hif-1α), as well as the epigenetic markers (hdac-1, dnmt1) by immunohistochemical, western blot, and rt-pcr analyses. |
2011-06-14 |
2023-08-12 |
Not clear |
| Tingting Chen, Gengyin Zhou, Quan Zhu, Xian Liu, Tuanzhu Ha, J L Kelley, R L Kao, D L Williams, Chuanfu L. Overexpression of vascular endothelial growth factor 165 (VEGF165) protects cardiomyocytes against doxorubicin-induced apoptosis. Journal of chemotherapy (Florence, Italy). vol 22. issue 6. 2011-06-09. PMID:21303748. |
cardiomyocyte apoptosis was evaluated by annexin v-fitc staining and by western blot detection of cleaved caspase-3. |
2011-06-09 |
2023-08-12 |
Not clear |
| Xiangmei Wu, Xing Liu, Joyeeta Sengupta, Youquan Bu, Faping Yi, Changdong Wang, Yanyan Shi, Yong Zhu, Qingfang Jiao, Fangzhou Son. Silencing of Bmi-1 gene by RNA interference enhances sensitivity to doxorubicin in breast cancer cells. Indian journal of experimental biology. vol 49. issue 2. 2011-05-31. PMID:21428211. |
apoptosis was detected by fcm and the expression of related genes [phosphor-akt (pakt), totle-akt (takt), bcl-2 and bax] was studied by western blot. |
2011-05-31 |
2023-08-12 |
mouse |
| Takayuki Ikezoe, Jing Yang, Chie Nishioka, Shinsuke Kojima, Asako Takeuchi, H Phillip Koeffler, Akihito Yokoyam. Inhibition of signal transducer and activator of transcription 5 by the inhibitor of janus kinases stimulates dormant human leukemia CD34+ /CD38- cells and sensitizes them to antileukemia agents. International journal of cancer. vol 128. issue 10. 2011-05-26. PMID:21128225. |
moreover, exposure of cd34(+) /cd38(-) cells to az960 potently induced apoptosis in parallel with downregulation of antiapoptotic protein bcl-xl, as measured by western blot analysis. |
2011-05-26 |
2023-08-12 |
human |
| Renshi Xu, Chengsi Wu, Xiong Zhang, Qiong Zhang, Yunzhu Yang, Juan Yi, Rongwei Yang, Yuhui Ta. Linking hypoxic and oxidative insults to cell death mechanisms in models of ALS. Brain research. vol 1372. 2011-05-03. PMID:21111718. |
exposure of nsc34 and pnc to cobalt chloride or chronic sustained hypoxic conditions showed a dramatic increase of cellular hif-1α (hypoxia inducing factor-1α), ho-1 (heme oxygenases-1), and ucp4 (uncoupling protein 4) expression by western blot analysis, accompanied with increasing cellular apoptosis by histone protein release assay. |
2011-05-03 |
2023-08-12 |
mouse |
| Renshi Xu, Chengsi Wu, Xiong Zhang, Qiong Zhang, Yunzhu Yang, Juan Yi, Rongwei Yang, Yuhui Ta. Linking hypoxic and oxidative insults to cell death mechanisms in models of ALS. Brain research. vol 1372. 2011-05-03. PMID:21111718. |
in an als mouse model, the caspase 3 activation, aif (apoptosis inducing factor), cytochrome c redistribution in mn of spinal cord significantly increased at 70days of disease progression, and hif-1α expression significantly increased at whole disease stages by an immunohistochemical positive cell counting and western blot analysis, respectively. |
2011-05-03 |
2023-08-12 |
mouse |
| Li-Chuan Hsu, Ya-Wen Hsu, Yu-Han Liang, Yao-Haur Kuo, Tzu-Ming Pa. Anti-tumor and anti-inflammatory properties of ankaflavin and monaphilone A from monascus purpureus NTU 568. Journal of agricultural and food chemistry. vol 59. issue 4. 2011-05-02. PMID:21261255. |
we employed a ssdna enzyme-linked immunosorbent assay (elisa) kit to investigate the nuclear changes of early apoptosis induced by ak and ma on hep-2 cells and used a western blot and an enzyme activity assay to demonstrate the activation of caspase-3, caspase-8, and caspase-9 by ma and ak. |
2011-05-02 |
2023-08-12 |
human |