| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fu-Xu Wang, Fang Zhao, Ling Pan, Xue-Jun Zhang, Jian-Min Luo, Jing-Ci Yang, Li Yao, Xing-Yan DU, Zuo-Ren Don. [Preliminary study on the effect of TRAIL on adhesion and apoptosis of multiple myeloma cell line RPMI8226 and its mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 1. 2011-10-06. PMID:20137126. |
the inhibition effects of trail on cells growth and adhesion were assayed by mtt; cell apoptosis was detected by annexin v and pi; expression of genes bax, bcl-2, mcl-1, carp1, carp2, xiap and cflip were determined by semi-quantitative rt-pcr; apoptosis-related protein expression was detected by western blot. |
2011-10-06 |
2023-08-12 |
Not clear |
| D R Kim, M-Y Park, C-S Lee, S-H Shim, H-I Yoon, J H Lee, M-W Sung, Y-S Kim, C-T Le. Combination of vorinostat and adenovirus-TRAIL exhibits a synergistic antitumor effect by increasing transduction and transcription of TRAIL in lung cancer cells. Cancer gene therapy. vol 18. issue 7. 2011-10-04. PMID:21455254. |
after combined treatment of vorinostat and ad-trail, apoptosis and western blot assays for akt, bcl-2 and caspase were performed. |
2011-10-04 |
2023-08-12 |
Not clear |
| Zhen-Hong Zhu, You-Shui Gao, Bing-Fang Zeng, Chang-Qing Zhan. The effect of dexamethasone and hypoxic stress on MC3T3-E1 cells. Frontiers in bioscience (Landmark edition). vol 16. 2011-10-03. PMID:21622206. |
flow cytometry, western blot and real-time quantitative pcr analyses revealed that hypoxia significantly enhanced dex-induced apoptosis. |
2011-10-03 |
2023-08-12 |
Not clear |
| G Bao, Y Han, M Wang, G X. Relationship between cellular apoptosis and the expression of p75 neurotrophin receptor and tyrosine kinase A receptor in tissue surrounding haematoma in intracerebral haemorrhage. The Journal of international medical research. vol 39. issue 1. 2011-10-03. PMID:21672317. |
cellular apoptosis was determined by terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick-end labelling (tunel), and p75(ntr) and trka location, protein and gene expression were studied using immunohistochemistry, western blot and real-time polymerase chain reaction, respectively. |
2011-10-03 |
2023-08-12 |
Not clear |
| Yong-Lan Ma, Hong Yi, Fei-Lan Yang, Yuan Zhang, Ya Wang, Ying Wan. [Celastrol down-regulates expression of P-Akt and cyclin D1 in HL-60 cells and induces apoptosis]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 4. 2011-09-30. PMID:20723296. |
the proliferative activity of hl-60 cells treated with 0.25 - 8.0 μmol/l of celastrol for 24 - 72 hours was assayed by mtt method, the effects of celastrol on apoptosis and cell cycle of hl-60 were detected by tunel staining and flow cytometry with annexin v-fitc/pi double labeling, the expression of pakt and cyclin d1 at protein and gene level in hl-60 cells treated with celastrol were measured by western blot and rt-pcr. |
2011-09-30 |
2023-08-12 |
Not clear |
| Ai-Mei Fei, Chao-Ming Mao, Jing-Jing Liu, Jiang Zhu, Jian-Qing M. [Effect of arsenic trioxide on induction of apoptosis in MCL cell line and its possible mechanisms]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 4. 2011-09-30. PMID:20723298. |
the expressions of cyclin d1 and apoptosis related proteins mcl-1, bcl-2, puma, noxa, ccaspase-3 (cleaved caspase-3), ccaspase-9 (cleaved caspase-9), cparp (cleaved parp) were detected by western blot. |
2011-09-30 |
2023-08-12 |
Not clear |
| Sophie Chen, Matt Cooper, Matt Jones, Thumuluru Kavitha Madhuri, Julie Wade, Ashleigh Bachelor, Simon Butler-Manue. Combined activity of oridonin and wogonin in advanced-stage ovarian cancer cells: sensitivity of ovarian cancer cells to phyto-active chemicals. Cell biology and toxicology. vol 27. issue 2. 2011-09-30. PMID:20872277. |
effects on cell cycle modulation and apoptosis were examined by flow cytometry and western blot analysis (wb). |
2011-09-30 |
2023-08-12 |
Not clear |
| Xiao-Hua Li, Tian-Yang Xue, Wei Xu, Ji-Zhao Ga. [Effect of proteasome inhibitor MG-132 on L1210 cell apoptosis and its mechanism]. Zhongguo shi yan xue ye xue za zhi. vol 18. issue 2. 2011-09-29. PMID:20416160. |
cell viability was tested by mtt assay, apoptosis rate was detected by using flow cytometry, activity of caspase 3 was detected by colorimetry, the expression of nf-kappab nuclear protein was detected by western blot. |
2011-09-29 |
2023-08-12 |
Not clear |
| Ranjita Misra, Sanjeeb K Saho. Coformulation of doxorubicin and curcumin in poly(D,L-lactide-co-glycolide) nanoparticles suppresses the development of multidrug resistance in K562 cells. Molecular pharmaceutics. vol 8. issue 3. 2011-09-23. PMID:21480667. |
moreover, western blot results confirm that in combination both of the drugs were capable of inducing apoptosis even if in a lower concentration compared to either single drug in both solution or in formulation. |
2011-09-23 |
2023-08-12 |
Not clear |
| Baozhu Sun, Lin Chen, Xinbing Wei, Yanxiao Xiang, Xiaoqian Liu, Xiumei Zhan. The Akt/GSK-3β pathway mediates flurbiprofen-induced neuroprotection against focal cerebral ischemia/reperfusion injury in rats. Biochemical and biophysical research communications. vol 409. issue 4. 2011-09-02. PMID:21624354. |
cell apoptosis, apoptosis-related proteins and the levels of p-akt and p-gsk-3β in ischemic penumbra were measured using tunel and western blot. |
2011-09-02 |
2023-08-12 |
rat |
| Kun Ji, Bo Wang, Yue-Ting Shao, Ling Zhang, Ya-Nan Liu, Chen Shao, Xiao-Jie Li, Xin Li, Jia-di Hu, Xue-Jian Zhao, De-Qi Xu, Yang Li, Lu Ca. Synergistic suppression of prostatic cancer cells by coexpression of both murine double minute 2 small interfering RNA and wild-type p53 gene in vitro and in vivo. The Journal of pharmacology and experimental therapeutics. vol 338. issue 1. 2011-08-30. PMID:21444629. |
cell growth, apoptosis, and the expression of related genes and proteins were examined in vitro and in vivo by flow cytometry and western blot assays. |
2011-08-30 |
2023-08-12 |
mouse |
| Ye Ji, Yi-Cai Zhang, Liu-Bao Pei, Li-Li Shi, Jing-Long Yan, Xue-Hua M. Anti-tumor effects of dihydroartemisinin on human osteosarcoma. Molecular and cellular biochemistry. vol 351. issue 1-2. 2011-08-26. PMID:21234653. |
then, cell proliferation was determined by the cck-8 viability assay; apoptosis and cell cycle progression were evaluated by flow cytometry; protein expression was analyzed by western blot assay; and nf-kb activity was examined by luciferase assay. |
2011-08-26 |
2023-08-12 |
human |
| K L Santucci, K K Snyder, J M Baust, R G Van Buskirk, V Mouraviev, T J Polascik, A A Gage, J G Baus. Use of 1,25α dihydroxyvitamin D3 as a cryosensitizing agent in a murine prostate cancer model. Prostate cancer and prostatic diseases. vol 14. issue 2. 2011-08-25. PMID:21221127. |
western blot analysis following calcitriol cryosensitization regimes confirmed the activation of apoptosis. |
2011-08-25 |
2023-08-12 |
Not clear |
| Ming-Fang Shen, Bao-An Chen, Jian Cheng, Feng Gao, Wen-Lin Xu, Jia-Hua Ding, Chong Gao, Xin-Chen Sun, Guo-Hong Li, Wen-Ji Chen, Li-Jie Liu, Xiao-Mao Li, Xue-Mei Wan. Effects of magnetic nanoparticle of fe(3)o(4) and 5-bromotetrandrine on apoptosis of K562/A02 leukemic cells induced by daunorubicin. Zhongguo shi yan xue ye xue za zhi. vol 17. issue 1. 2011-08-23. PMID:19236747. |
the apoptosis was detected by flow cytometry (fcm), wright staining and light microscope; the expressions of bax and bcl-2 were measured by western blot. |
2011-08-23 |
2023-08-12 |
Not clear |
| Junhao Yan, Li Li, Nikan H Khatibi, Lei Yang, Ke Wang, Weiguang Zhang, Robert D Martin, Jingyan Han, John Zhang, Changman Zho. Blood-brain barrier disruption following subarchnoid hemorrhage may be faciliated through PUMA induction of endothelial cell apoptosis from the endoplasmic reticulum. Experimental neurology. vol 230. issue 2. 2011-08-15. PMID:21586287. |
immunohistochemical staining and western blot analysis demonstrated an increased expression of puma, bax, bak, grp78 and drp1 in the microvascular endothelial cells of the hippocampus, which was accompanied with endothelium apoptosis. |
2011-08-15 |
2023-08-12 |
rat |
| Bharathi Gorantla, Swapna Asuthkar, Jasti S Rao, Jitendra Patel, Christopher S Gond. Suppression of the uPAR-uPA system retards angiogenesis, invasion, and in vivo tumor development in pancreatic cancer cells. Molecular cancer research : MCR. vol 9. issue 4. 2011-08-09. PMID:21389187. |
in addition, western blot analysis revealed that downregulation of upar and upa caused the activation of caspase 8 and cad, which is indicative of apoptosis, and in vivo tunel assay confirmed these results. |
2011-08-09 |
2023-08-12 |
Not clear |
| Hai Huang, Yunyuan Zhang, Xin Liu, Zhanwei Li, Wenfen Xu, Shunzhi He, Yunzhu Huang, Hua Zhan. Acid sphingomyelinase contributes to evodiamine-induced apoptosis in human gastric cancer SGC-7901 cells. DNA and cell biology. vol 30. issue 6. 2011-08-04. PMID:21294641. |
protein expression of asmase, which was exposed to evodiamine, was shown to be increased by western blot analysis and could have been responsible for inducing caspase-independent apoptosis. |
2011-08-04 |
2023-08-12 |
human |
| Rida Fares, Samer Bazzi, Serine E Baydoun, Roula M Abdel-Massi. The antioxidant and anti-proliferative activity of the Lebanese Olea europaea extract. Plant foods for human nutrition (Dordrecht, Netherlands). vol 66. issue 1. 2011-08-04. PMID:21318304. |
to study whether cell death was due to apoptosis, cells were stained with annexin v-fitc and pi and the expression of important regulatory proteins (bcl-2, bax, and p53) involved in apoptosis were examined by western blot. |
2011-08-04 |
2023-08-12 |
human |
| Shih-Ming Huang, Jai-Sing Yang, Shih-Chang Tsai, Ming-Hua Chen, Mei-Hua Hsu, Hui-Yi Lin, Li-Chen Chou, Jo-Hua Chinag, Kuo-Hsiung Lee, Li-Jiau Huang, Sheng-Chu Ku. The novel synthesized 2-(3-(methylamino)phenyl)-6-(pyrrolidin-1-yl)quinolin-4-one (Smh-3) compound induces G2/M phase arrest and mitochondrial-dependent apoptotic cell death through inhibition of CDK1 and AKT activity in HL-60 human leukemia cells. International journal of oncology. vol 38. issue 5. 2011-08-03. PMID:21344160. |
results from colorimetric assays and western blot analysis indicated that activities of caspase-9, -7 and -3 were promoted in smh-3-treated hl-60 cells during cell apoptosis. |
2011-08-03 |
2023-08-12 |
human |
| Xuequan Feng, Biao Zhang, Jinhuan Wang, Xinnv Xu, Na Lin, Hongsheng Li. Adenovirus-mediated transfer of siRNA against basic fibroblast growth factor mRNA enhances the sensitivity of glioblastoma cells to chemotherapy. Medical oncology (Northwood, London, England). vol 28. issue 1. 2011-08-02. PMID:20221717. |
apoptosis of u251 cells was detected using hoechst staining and flow cytometry, with expression of apoptosis-related proteins evaluated by western blot. |
2011-08-02 |
2023-08-12 |
Not clear |