| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Raúl Vivar, Claudio Humeres, Marcelo Varela, Pedro Ayala, Nancy Guzmán, Ivonne Olmedo, Mabel Catalán, Pía Boza, Claudia Muñoz, Guillermo Díaz Aray. Cardiac fibroblast death by ischemia/reperfusion is partially inhibited by IGF-1 through both PI3K/Akt and MEK-ERK pathways. Experimental and molecular pathology. vol 93. issue 1. 2012-08-24. PMID:22537549. |
cell viability was evaluated by trypan blue assay, and apoptosis by a facs flow cytometer; p-erk-1/2 and p-akt levels were determined by western blot. |
2012-08-24 |
2023-08-12 |
rat |
| Ting-Tsz Ou, Chau-Jong Wang, Guang-Uei Hung, Cheng-Hsun Wu, Huei-Jane Le. Aqueous Extract of Shi-Liu-Wei-Liu-Qi-Yin Induces G2/M Phase Arrest and Apoptosis in Human Bladder Carcinoma Cells via Fas and Mitochondrial Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2011. 2012-08-23. PMID:19383839. |
we evaluated the effects of slwlqy on apoptosis-related experiments inducing in tsgh-8301 cells by (i) 3-(4,5-dimethylthiazol-zyl)-2,5-diphenylterazolium bromide (mtt) for cytotoxicity; (ii) cell-cycle analysis and (iii) western blot analysis of the g2/m-phase and apoptosis regulatory proteins. |
2012-08-23 |
2023-08-12 |
mouse |
| Fang Zeng, Yun Cheng Li, Gang Chen, Yong Kui Zhang, Ye Kai Wang, Shi Quan Zhou, Li Na Ma, Ji Hang Zhou, Yan Yan Huang, Wang Yu Zhu, Xiao Guang Li. Nicotine inhibits cisplatin-induced apoptosis in NCI-H446 cells. Medical oncology (Northwood, London, England). vol 29. issue 1. 2012-08-23. PMID:21267677. |
an mtt assay, annexin v-fitc staining, rt-pcr, and western blot were applied to identify the viability of cells, stages of apoptosis, mrna and signaling proteins expression, respectively. |
2012-08-23 |
2023-08-12 |
Not clear |
| Do-Hoon Lee, Kwang-Il Park, Hyeon-Soo Park, Sang-Rim Kang, Arulkumar Nagappan, Jin-A Kim, Eun-Hee Kim, Won-Sup Lee, Young-Sool Hah, Hyon-Jong Chung, Su-Jin An, Gon-Sup Ki. Flavonoids Isolated from Korea Citrus aurantium L. Induce G2/M Phase Arrest and Apoptosis in Human Gastric Cancer AGS Cells. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-08-23. PMID:22194772. |
western blot was used to detect the expression of protein related with cell cycle and apoptosis. |
2012-08-23 |
2023-08-12 |
human |
| Fafeng Cheng, Xianggen Zhong, Yi Lu, Xueqian Wang, Wenting Song, Shaoying Guo, Xiaotong Wang, Dantong Liu, Qingguo Wan. Refined Qingkailing Protects MCAO Mice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window. Evidence-based complementary and alternative medicine : eCAM. vol 2012. 2012-08-23. PMID:22536287. |
neurological function and brain infarction were examined and cell apoptosis and ros at prefrontal cortex were evaluated 24 h after mcao, and western blot and intracellular calcium were also researched, respectively. |
2012-08-23 |
2023-08-12 |
mouse |
| Baiye Jin, Guanghou Fu, Hao Pan, Xiaofei Cheng, Lin Zhou, Jia Lv, Geming Chen, Shusen Zhen. Anti-tumour efficacy of mitofusin-2 in urinary bladder carcinoma. Medical oncology (Northwood, London, England). vol 28 Suppl 1. 2012-08-22. PMID:20803103. |
the effects of mfn2 on cell-cycle distribution and apoptosis were assessed by flow cytometry and western blot analyses. |
2012-08-22 |
2023-08-12 |
Not clear |
| Armen V Gyulkhandanyan, Asuman Mutlu, John Freedman, Valery Leyti. Markers of platelet apoptosis: methodology and applications. Journal of thrombosis and thrombolysis. vol 33. issue 4. 2012-08-20. PMID:22383127. |
methods commonly employed in studies of platelet apoptosis markers include flow cytometry, western blot analysis and electron microscopy. |
2012-08-20 |
2023-08-12 |
human |
| V M Ragaseema, S Unnikrishnan, V Kalliyana Krishnan, Lissy K Krishna. The antithrombotic and antimicrobial properties of PEG-protected silver nanoparticle coated surfaces. Biomaterials. vol 33. issue 11. 2012-08-15. PMID:22284585. |
inhibitory effects demonstrated are on: platelet function by aggregometry, exposure of activation and apoptosis markers by flow cytometry, biochemical pathway by malondealdehyde (mda) estimation and protein phosphorylation by western blot. |
2012-08-15 |
2023-08-12 |
Not clear |
| Bradley L Baumgarner, Catherine P Riley, Maria S Sepulveda, Paul B Brown, Jennifer L Meyer, Jiri Adame. Increased expression of GAPDH protein is not indicative of nitrosative stress or apoptosis in liver of starved rainbow trout (Oncorhynchus mykiss). Fish physiology and biochemistry. vol 38. issue 2. 2012-07-31. PMID:21647598. |
dot blot and dna fragmentation analyses were conducted to evaluate protein s-nitrosylation and apoptosis, respectively. |
2012-07-31 |
2023-08-12 |
Not clear |
| Cuicui Wang, Ming Liu, Linyou Cheng, Jianteng Wei, Ning Wu, Lanhong Zheng, Xiukun Li. A novel polypeptide from Meretrix meretrix Linnaeus inhibits the growth of human lung adenocarcinoma. Experimental biology and medicine (Maywood, N.J.). vol 237. issue 4. 2012-07-20. PMID:22522344. |
western blot analysis showed that the intrinsic pathway was involved in mere15-induced apoptosis. |
2012-07-20 |
2023-08-12 |
mouse |
| Qi Zhan, Wu Yue, Hu Shaosha. The inhibitory effect of photodynamic therapy and of an anti-VCAM-1 monoclonal antibody on the in vivo growth of C6 glioma xenografts. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 44. issue 5. 2012-07-17. PMID:21519637. |
at day 21, 5 rats in each group were sacrificed and cancers were harvested for immunohistochemistry and western blot assay for the detection of vcam-1, and tunel assay was used to detect apoptosis. |
2012-07-17 |
2023-08-12 |
rat |
| Gunasekaran Sivagami, Rajamanickam Vinothkumar, Roberta Bernini, Christo Paul Preethy, Anvarbatcha Riyasdeen, Mohammad Abdulkader Akbarsha, Venugopal Padmanaban Menon, Namasivayam Nalin. Role of hesperetin (a natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line--a comparative study. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 50. issue 3-4. 2012-07-16. PMID:22142698. |
results of western blot analysis of apoptosis associated genes revealed an increase in cytochrome c, bax, cleaved caspase-3 expression and a decrease in bcl-2 expression. |
2012-07-16 |
2023-08-12 |
human |
| Shaohua Zhu, Jing Jin, Yan Wang, Zizhang Ouyang, Chen Xi, Jia Li, Yuwen Qiu, Jinzhi Wan, Min Huang, Zhiying Huan. The endoplasmic reticulum stress response is involved in apoptosis induced by aloe-emodin in HK-2 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 50. issue 3-4. 2012-07-16. PMID:22210228. |
apoptosis of the cells was associated with caspase 3 activation, which was detected by western blot analysis and a caspase activity assay. |
2012-07-16 |
2023-08-12 |
human |
| Wang Li, Lynn T Frame, Karlene A Hoo, Yuan Li, Nicholas D'Cunha, Everardo Cobo. Genistein inhibited proliferation and induced apoptosis in acute lymphoblastic leukemia, lymphoma and multiple myeloma cells in vitro. Leukemia & lymphoma. vol 52. issue 12. 2012-07-13. PMID:21749310. |
the concomitant altered expression of apoptosis pathway proteins and cell cycle modulators (caspases 9, 3, 7, parp [poly(adp-ribose) polymerase], ciap1 [inhibitor of apoptosis protein 1], bcl-2 and cyclin b1) were observed by western blot and real-time polymerase chain reaction (pcr) analyses. |
2012-07-13 |
2023-08-12 |
Not clear |
| Zhi-Gang Mao, Jing Zhou, Hui Wang, Dong-Sheng He, Wei-Wei Xiao, Gui-Zhi Liao, Lu-Bin Qiu, Yong-Hong Zhu, Hai-Jun Wan. Artesunate inhibits cell proliferation and decreases growth hormone synthesis and secretion in GH3 cells. Molecular biology reports. vol 39. issue 5. 2012-07-12. PMID:22215215. |
we also analyzed cell apoptosis and cell cycle stage by flow cytometry, semi-quantitative rt-pcr analysis for the expression of gh mrna and apoptosis-induced factor (aif) mrna, analysis of gh protein by western blot, elisa detection of secreted gh, and the caspase inhibition assay. |
2012-07-12 |
2023-08-12 |
mouse |
| Dongxu He, Xin Ma, Yun Chen, Yanfei Cai, Xiaochen Ru, Iain C Bruce, Qiang Xia, Guiyang Shi, Jian Ji. Luteolin inhibits pyrogallol-induced apoptosis through the extracellular signal-regulated kinase signaling pathway. The FEBS journal. vol 279. issue 10. 2012-07-12. PMID:22394505. |
the effect of luteolin on pyrogallol-induced superoxide stress and the subsequent apoptosis was studied in the mouse heart capillary endothelial cell line h5v and human umbilical vein endothelial cells, by the use of flow cytometry, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide, hoechst staining, and western blot. |
2012-07-12 |
2023-08-12 |
mouse |
| Manish V Bais, Matthew A Nugent, Danielle N Stephens, S Selva Sume, Kathrin H Kirsch, Gail E Sonenshein, Philip C Trackma. Recombinant lysyl oxidase propeptide protein inhibits growth and promotes apoptosis of pre-existing murine breast cancer xenografts. PloS one. vol 7. issue 2. 2012-06-29. PMID:22363577. |
tumors were monitored for growth, and after sacrifice were subjected to immunohistochemical and western blot analyses for several markers of proliferation, apoptosis, and for rlox-pp itself. |
2012-06-29 |
2023-08-12 |
mouse |
| Jie Fu, Bijun Zhao, Zhouhuan Dong, Yunjuan Sun, Haofei Luan, Xianfei Shen, Xin Gao, Feng Gong, Subo Li, Haifeng Son. Heparanase DNA vaccine delivered by electroporation induces humoral immunity and cytoimmunity in animal models. Vaccine. vol 30. issue 12. 2012-06-22. PMID:22240343. |
in addition, rt-pcr and western blot analyses of the primary tumors indicated less proliferation and angiogenesis and more apoptosis in the hpa-immunization immunotherapy groups. |
2012-06-22 |
2023-08-12 |
mouse |
| Zheng-Quan Yu, Ji-Hui Zh. Genetic ablation of toll-like receptor 2 reduces secondary brain injury caused by cortical contusion in mice. Annals of clinical and laboratory science. vol 42. issue 1. 2012-06-14. PMID:22371907. |
we measured tlr2 by western blot; motor function by grip test; brain edema by wet/dry method; cortical apoptosis by terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) method; and il-1β, tnf-α and il-6 by enzyme-linked immunosorbent assay (elisa). |
2012-06-14 |
2023-08-12 |
mouse |
| S-C DU, Q-M Ge, N Lin, Y Dong, Q S. ROS-mediated lipopolysaccharide-induced apoptosis in INS-1 cells by modulation of Bcl-2 and Bax. Cellular and molecular biology (Noisy-le-Grand, France). vol 58 Suppl. 2012-06-12. PMID:22455982. |
apoptosis rate of lps stimulated ins-1 cells is significantly increased by fcm, with a significant increase in bax/bcl-2 ratio revealed by western blot and rt-pcr. |
2012-06-12 |
2023-08-12 |
rat |