| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mario Augusto Bolaños-Carrillo, Jose Luis Ventura-Gallegos, Arturo David Saldivar-Jiménez, Alejandro Zentella-Dehesa, Mariano Martínez-Vázque. Effect of Sterols Isolated from Myrtillocactus geometrizans on Growth Inhibition of Colon and Breast Cancer Cells. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-06-26. PMID:26113867. |
cell apoptosis was detected through both annexin-v fluos/pi double-labeled cytometry assays and western blot was applied to assess parp cleavage. |
2015-06-26 |
2023-08-13 |
Not clear |
| Wen-Xiao Xu, Yang Liu, Sheng-Zhi Liu, Yu Zhang, Guo-Fen Qiao, Jinglong Ya. Arsenic trioxide exerts a double effect on osteoblast growth in vitro. Environmental toxicology and pharmacology. vol 38. issue 2. 2015-06-23. PMID:25128771. |
cell survives, apoptosis, collagen, and molecular targets were identified by multiple detecting techniques, including mtt assay, electron microscopy, collagen detecting kit, tunel kit, and western blot in hfob1.19 human osteoblasts cell line. |
2015-06-23 |
2023-08-13 |
human |
| Charng Choon Wong, Sreenivasa Rao Sagineedu, Shariful Hasan Sumon, Shiran Mohamad Sidik, Roger Phillips, Nordin H Lajis, Johnson Stansla. NCI in vitro and in silico anticancer screen, cell cycle pertubation and apoptosis-inducing potential of new acylated, benzylidene and isopropylidene derivatives of andrographolide. Environmental toxicology and pharmacology. vol 38. issue 2. 2015-06-23. PMID:25168151. |
western blot analysis of srs07-treated hct116 cells revealed that the compound induced apoptosis be activating caspase 8 which in turn cleaved bid to t-bid to initiate cell death cascade. |
2015-06-23 |
2023-08-13 |
Not clear |
| Christina Pfister, Heike Pfrommer, Marcos S Tatagiba, Florian Rose. Detection and quantification of apoptosis in primary cells using Taqman® protein assay. Methods in molecular biology (Clifton, N.J.). vol 1219. 2015-06-23. PMID:25308262. |
using this technique, we can not only detect apoptosis with a 1,000-fold higher sensitivity than western blot, but we can also exactly quantify cleaved caspase-3 expression. |
2015-06-23 |
2023-08-13 |
Not clear |
| Wei Tan, Hong-Gang Yu, He-Sheng Lu. Inhibition of the p38 MAPK pathway sensitizes human gastric cells to doxorubicin treatment in vitro and in vivo. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25270341. |
the effect of doxorubicin on the growth and apoptosis of gastric cancer cells in the presence or absence of sb203580 was investigated by western blot analysis, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, hoechst staining, annexin v-fitc/propidium iodide staining followed by flow cytometry analysis, and the terminal deoxynucleotidyl transferase-mediated dutp nick end labeling (tunel) assay. |
2015-06-19 |
2023-08-13 |
human |
| Dong Li, Li-Nan Zhao, Xiu-Lan Zheng, Ping Lin, Feng Lin, Yue Li, Hai-Feng Zou, Rong-Jun Cui, Hui Chen, Xiao-Guang Y. Sox2 is involved in paclitaxel resistance of the prostate cancer cell line PC-3 via the PI3K/Akt pathway. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25310235. |
western blot analysis revealed that the phosphoinositide 3-kinase/akt signaling pathway was activated in cells overexpressing sox2, and by targeting cyclin e and survivin, sox2 promoted g1/s phase transition and prevented apoptosis under pac treatment. |
2015-06-19 |
2023-08-13 |
Not clear |
| Yuanming Jing, Suxia Guo, Xiaoping Zhang, Aijing Sun, Feng Tao, Haixing Ju, Haixin Qia. Effects of small interfering RNA interference of connexin 37 on subcutaneous gastric tumours in mice. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25310476. |
following six weeks, the cx37 mrna expression, cx37 protein expression and tumor apoptosis were detected using semiquantitative reverse transcription‑polymerase chain reaction, western blot analysis and terminal deoxynucleotidyl transferase‑mediated dutp nick end labelling, respectively. |
2015-06-19 |
2023-08-13 |
mouse |
| Tao Feng, Guanglei Qiao, Li Feng, Weixiang Qi, Yujing Huang, Yang Yao, Zan She. Stathmin is key in reversion of doxorubicin resistance by arsenic trioxide in osteosarcoma cells. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25310700. |
the current study investigated the effects of as2o3 on mg63 osteosarcoma cells using a cell proliferation assay, flow cytometric analysis of the cell cycle and cell apoptosis, reverse transcription polymerase chain reaction to detect stathmin mrna expression levels and western blot analysis to detect the stathmin protein expression levels. |
2015-06-19 |
2023-08-13 |
Not clear |
| Xuezhen Li, Xin He, Wei Tian, Jianzhen Wan. Short hairpin RNA targeting Notch2 inhibits U87 human glioma cell proliferation by inducing cell cycle arrest and apoptosis in vitro and in vivo. Molecular medicine reports. vol 10. issue 6. 2015-06-19. PMID:25323114. |
mrna and protein expression, cell proliferation, cell cycle and apoptosis were measured by reverse transcription‑polymerase chain reaction, western blot analysis, 3‑(4,5‑dimethylthiazol‑2‑yl)‑2,5‑diphenyltetrazolium bromide analysis and flow cytometry using propidium iodide, respectively. |
2015-06-19 |
2023-08-13 |
mouse |
| Yan Jing Li, Peng Huang, Cai Ling Jiang, De Xin Jia, Xiao Xue Du, Jian Hua Zhou, Yu Han, Hong Sui, Xiao Li Wei, Lei Liu, Heng Heng Yuan, Ting Ting Zhang, Wen Jie Zhang, Rui Xie, Xiao Hui Lang, Li Ying Wang, Tao Liu, Yu Xian Bai, Ye Tia. Sonodynamically induced anti-tumor effect of 5-aminolevulinic acid on pancreatic cancer cells. Ultrasound in medicine & biology. vol 40. issue 11. 2015-06-18. PMID:25220273. |
cell viability was determined by mtt (3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyltetrazolium bromide) analysis; mitochondrial membrane potential was assessed using the fluorescent probe jc-1; apoptosis was evaluated by flow cytometry; cell morphology was investigated by scanning electron microscopy; apoptosis-related protein expression was analyzed by western blot assay. |
2015-06-18 |
2023-08-13 |
human |
| Huidi Liu, Yan Yan, Haixia Wen, Xueli Jiang, Xuefeng Cao, Guangmei Zhang, Guoyi Li. A novel estrogen receptor GPER mediates proliferation induced by 17β-estradiol and selective GPER agonist G-1 in estrogen receptor α (ERα)-negative ovarian cancer cells. Cell biology international. vol 38. issue 5. 2015-06-15. PMID:24446390. |
protein expression of marker genes of proliferation, cell cycle and apoptosis were examined by western blot. |
2015-06-15 |
2023-08-12 |
Not clear |
| Pengfei Yu, Liang Ye, Hongbo Wang, Guangying Du, Jianzhao Zhang, Jinghai Zhang, Jingwei Tia. NSK-01105 inhibits proliferation and induces apoptosis of prostate cancer cells by blocking the Raf/MEK/ERK and PI3K/Akt/mTOR signal pathways. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 3. 2015-06-15. PMID:25398692. |
the effects of nsk-01105 on proliferation and apoptosis of prostate cancer cells were established by cytotoxicity assays, apoptosis analysis, flow cytometry analysis, and western blot analysis. |
2015-06-15 |
2023-08-13 |
human |
| Taofeng Zhu, Ruhua Chen, Hao Yu, Yan Feng, Jianqiang Chen, Qin Lu, Jing Xie, Weiliang Ding, Tieliang M. Antitumor effect of a copper (II) complex of a coumarin derivative and phenanthroline on lung adenocarcinoma cells and the mechanism of action. Molecular medicine reports. vol 10. issue 5. 2015-06-09. PMID:25176185. |
an mtt assay was performed to determine the cell proliferation ratio, cell apoptosis was detected by annexin v/propidium iodide staining with flow cytometric analysis and western blot analysis was employed to evaluate the expression levels of apoptosis-associated proteins. |
2015-06-09 |
2023-08-13 |
mouse |
| Dongdong Zhang, Junpeng Qi, Rui Liu, Bingling Dai, Weina Ma, Yingzhuan Zhan, Yanmin Zhan. c-Myc plays a key role in TADs-induced apoptosis and cell cycle arrest in human hepatocellular carcinoma cells. American journal of cancer research. vol 5. issue 3. 2015-06-05. PMID:26045987. |
using genome-wide microarray analysis, we found the down-regulated growth and apoptosis factors, and selected down-regulated genes were confirmed by western blot. |
2015-06-05 |
2023-08-13 |
human |
| W Chaouki, B Meddah, M Hmamouch. Antiproliferative and apoptotic potential of Daphne gnidium L. root extract on lung cancer and hepatoma cells. Die Pharmazie. vol 70. issue 3. 2015-06-02. PMID:25980182. |
the characterization of the mechanisms involved in this effect was determined by lactate dehydrogenase test, apoptosis assays and western blot analyses. |
2015-06-02 |
2023-08-13 |
human |
| Xu-Hui Zhou, Chao-Qun Yang, Cheng-Lin Zhang, Yang Gao, Hong-Bin Yuan, Ce Wan. RASSF5 inhibits growth and invasion and induces apoptosis in osteosarcoma cells through activation of MST1/LATS1 signaling. Oncology reports. vol 32. issue 4. 2015-06-01. PMID:25109282. |
a gain-of-function approach was used to observe the effects of lentiviral vector-mediated overexpression of rassf5 (lv-rassf5) on cell growth, invasion and apoptosis, respectively, as indicated by mtt, transwell and flow cytometry assays, and the expression levels of mammalian sterile 20-like (mst1) kinase, large tumor suppressor 1 (lats1), proliferating cell nuclear antigen (pcna), matrix metallopeptidase-9 (mmp-9) and p53 were detected by real-time pcr and western blot assays in os cells (mg-63 and u-2 os). |
2015-06-01 |
2023-08-13 |
human |
| Xing Ai, Zhuomin Jia, Shuanglin Liu, Jiajun Wang, Xu Zhan. Notch-1 regulates proliferation and differentiation of human bladder cancer cell lines by inhibiting expression of Krüppel-like factor 4. Oncology reports. vol 32. issue 4. 2015-06-01. PMID:25109409. |
cell proliferation, apoptosis and expression of notch-1 and klf4 were assessed using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (mtt) assay, flow cytometry assay with annexin v-fitc/pi staining, and reverse transcriptase polymerase chain reaction (rt-pcr) and western blot analysis, respectively. |
2015-06-01 |
2023-08-13 |
human |
| Nanzheng Chen, Qianqian Geng, Jianbao Zheng, Sai He, Xiongwei Huo, Xuejun Su. Suppression of the TGF-β/Smad signaling pathway and inhibition of hepatic stellate cell proliferation play a role in the hepatoprotective effects of curcumin against alcohol-induced hepatic fibrosis. International journal of molecular medicine. vol 34. issue 4. 2015-05-26. PMID:25069637. |
in this study, serum alkaline phosphatase (alp), aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels were measured to assess hepatic function; histopathological and immunohistochemical observations were used to evaluate pathological and specific molecular changes in liver tissue and flow cytometry was used to detect the apoptosis in cultured hepatic stellate cells (hscs), the major fibrogenic cells in the liver; pcr and western blot analysis were employed to evaluate the changes in the expression of molecules and signaling pathways. |
2015-05-26 |
2023-08-13 |
Not clear |
| Bo Huang, Hongli Zhou, Xianping Lang, Zhiliang Li. siRNA‑induced ABCE1 silencing inhibits proliferation and invasion of breast cancer cells. Molecular medicine reports. vol 10. issue 4. 2015-05-22. PMID:25070080. |
the effect of abce1 knockdown on cell proliferation, invasion, apoptosis and gene expression was then assessed using mtt assay, transwell migration assay, flow cytometry and western blot analysis, respectively. |
2015-05-22 |
2023-08-13 |
human |
| Yanyan Hu, Li Li, Wenbin Yin, Lin Shen, Beian You, Haiqing Ga. Protective effect of proanthocyanidins on anoxia-reoxygenation injury of myocardial cells mediated by the PI3K/Akt/GSK-3β pathway and mitochondrial ATP-sensitive potassium channel. Molecular medicine reports. vol 10. issue 4. 2015-05-22. PMID:25109283. |
myocardial apoptosis was also examined by terminal deoxynucleotidyl transferase dutp nick end labeling staining and western blot analysis was employed to detect the expression levels of caspase-3, p-akt and p-glycogen synthase kinase (gsk)-3β. |
2015-05-22 |
2023-08-13 |
rat |