| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marjan Shariatpanahi, Fariba Khodagholi, Ghorbangol Ashabi, Azar Aghazadeh Khasraghi, Leila Azimi, Mohammad Abdollahi, Mohammad Hossein Ghahremani, Seyed Nasser Ostad, Farshid Noorbakhsh, Mohammad Sharifzade. Ameliorating of Memory Impairment and Apoptosis in Amyloid β-Injected Rats Via Inhibition of Nitric Oxide Synthase: Possible Participation of Autophagy. Iranian journal of pharmaceutical research : IJPR. vol 14. issue 3. 2015-09-02. PMID:26330869. |
we also assessed the apoptosis and autophagy markers as two possible interfering pathways with no signaling by western blot method. |
2015-09-02 |
2023-08-13 |
rat |
| Fang Xie, Lin Jia, Minghua Lin, Ying Shi, Jiming Yin, Yin Liu, Dexi Chen, Qinghua Men. ASPP2 attenuates triglycerides to protect against hepatocyte injury by reducing autophagy in a cell and mouse model of non-alcoholic fatty liver disease. Journal of cellular and molecular medicine. vol 19. issue 1. 2015-08-31. PMID:25256142. |
autophagy, apoptosis markers and lipid metabolism mediators, were assessed with confocal fluorescence microscopy, immunohistochemistry, western blot and biochemical assays. |
2015-08-31 |
2023-08-13 |
mouse |
| Dong Hoon Kwak, Ji-Hye Park, Hak-Seung Lee, Ji-Sook Moon, Seoul Le. Aristolochic Acid I induces ovarian toxicity by inhibition of akt phosphorylation. Chemical research in toxicology. vol 27. issue 12. 2015-08-21. PMID:25406029. |
we used chinese hamster ovary-k1 (cho-k1) cells and an aai injection mouse model: mtt assay was used to assess aa toxicity to cells; ovary size and weight were measured to determine the toxicity of aa to mouse ovary; western blot was used to assess apoptosis; tunel assay was used to evaluate apoptotic cell death; and immunohistochemistry was used to examine the local expression of apoptotic proteins in ovary tissue. |
2015-08-21 |
2023-08-13 |
mouse |
| Jong Seok Lee, Young Rae Kim, In Gyu Song, Suk-Jin Ha, Young Eon Kim, Nam-In Baek, Eock Kee Hon. Cyanidin-3-glucoside isolated from mulberry fruit protects pancreatic β-cells against oxidative stress-induced apoptosis. International journal of molecular medicine. vol 35. issue 2. 2015-08-21. PMID:25435295. |
immunofluorescence staining, flow cytometry and western blot analysis were also used to determine apoptosis and the expression of proteins associated with apoptosis. |
2015-08-21 |
2023-08-13 |
Not clear |
| J Cao, Q Miao, J Zhang, S Miao, L Bi, S Zhang, Q Yang, X Zhou, M Zhang, Y Xie, S Wan. INHIBITORY EFFECT OF TETRAMETHYLPYRAZINE ON HEPATOCELLULAR CARCINOMA: POSSIBLE ROLE OF APOPTOSIS AND CELL CYCLE ARREST. Journal of biological regulators and homeostatic agents. vol 29. issue 2. 2015-08-21. PMID:26122217. |
apoptosis and cell cycle arrest-related makers and signaling cascades were determined by western blot, rt-pcr and flow cytometric analysis. |
2015-08-21 |
2023-08-13 |
rat |
| Ra Ham Lee, Jae-Cheon Shin, Ka-Hwi Kim, Yung Hyun Choi, Jung-Il Chae, Jung-Hyun Shi. Apoptotic effects of 7,8-dihydroxyflavone in human oral squamous cancer cells through suppression of Sp1. Oncology reports. vol 33. issue 2. 2015-08-20. PMID:25434704. |
we demonstrated that 7,8-dhf decreased cell growth and induced apoptosis in the hn22 and hsc4 cells through regulation of specificity protein 1 (sp1) using the mts assay, dapi staining, annexin v, propidium iodide staining, reverse transcription-polymerase chain reaction, immunocytochemistry, pull-down assay and western blot analysis. |
2015-08-20 |
2023-08-13 |
human |
| Chun-Yu Liu, Jung-Chen Su, Mei-Huei Ni, Ling-Ming Tseng, Pei-Yi Chu, Duen-Shian Wang, Wei-Tien Tai, Yuan-Ping Kao, Man-Hsin Hung, Chung-Wai Shiau, Kuen-Feng Che. Obatoclax analog SC-2001 inhibits STAT3 phosphorylation through enhancing SHP-1 expression and induces apoptosis in human breast cancer cells. Breast cancer research and treatment. vol 146. issue 1. 2015-08-18. PMID:24903225. |
apoptosis was examined by both flow cytometry and western blot. |
2015-08-18 |
2023-08-13 |
mouse |
| C Humeres, J Montenegro, M Varela, P Ayala, R Vivar, A Letelier, I Olmedo, M Catalán, C Rivas, P Baeza, C Muñoz, L García, S Lavandero, G Díaz-Aray. 4-Phenylbutyric acid prevent cytotoxicity induced by thapsigargin in rat cardiac fibroblast. Toxicology in vitro : an international journal published in association with BIBRA. vol 28. issue 8. 2015-08-18. PMID:25149584. |
neonate rat cf were treated with thapsigargin in presence or absence of 4-pba, and cell viability was evaluated by trypan blue exclusion and apoptosis by flow cytometry; whereas chop, bip, pdi, atf4 and procollagen protein levels were assessed by western blot. |
2015-08-18 |
2023-08-13 |
rat |
| Xiaoli Ma, Hua Duan, Jia Liu, Qingqing Mo, Chengjuan Sun, Ding Ma, Jiandong Wan. Effect of LIV1 on the sensitivity of ovarian cancer cells to trichostatin A. Oncology reports. vol 33. issue 2. 2015-08-11. PMID:25420545. |
using western blot analysis, we demostrated that the inhibition of tsa-induced apoptosis by knockdown of liv1 might be associated with decreased endogenous levels of bcl-2, enhanced levels of bax and cleavage of procaspase-3. |
2015-08-11 |
2023-08-13 |
Not clear |
| Chang Su, Hongdan Li, Yijie Shi, Guan Wang, Liwei Liu, Liang Zhao, Rongjian S. Carboxymethyl-β-cyclodextrin conjugated nanoparticles facilitate therapy for folate receptor-positive tumor with the mediation of folic acid. International journal of pharmaceutics. vol 474. issue 1-2. 2015-08-07. PMID:25149123. |
from in vitro cytotoxicity assay, cell apoptosis study, intracellular atp level assay and western blot, we can see that fa-cm-β-cd-bsa nps as good monodispersity, negative charge, and homogenous particle size have a high encapsulation efficiency. |
2015-08-07 |
2023-08-13 |
Not clear |
| Abderezak Zebboudj, Mohamed Ali Maroui, Jacques Dutrieux, Chafia Touil-Boukoffa, Mehdi Bourouba, Mounira K Chelbi-Alix, Sébastien Nisol. Sodium arsenite induces apoptosis and Epstein-Barr virus reactivation in lymphoblastoid cells. Biochimie. vol 107 Pt B. 2015-08-06. PMID:25241256. |
by flow-cytometry and western blot analysis, we provide evidence that naaso2 induced caspase-dependent apoptosis whereas as2o3 triggered autophagic cell death. |
2015-08-06 |
2023-08-13 |
Not clear |
| Chun-Hui Zhang, Ming-Wu Zheng, Ya-Ping Li, Xing-Dong Lin, Mei Huang, Lei Zhong, Guo-Bo Li, Rong-Jie Zhang, Wan-Ting Lin, Yan Jiao, Xiao-Ai Wu, Jiao Yang, Rong Xiang, Li-Juan Chen, Ying-Lan Zhao, Wei Cheng, Yu-Quan Wei, Sheng-Yong Yan. Design, Synthesis, and Structure-Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast Cancer. Journal of medicinal chemistry. vol 58. issue 9. 2015-08-06. PMID:25835317. |
western blot and immunohistochemical assays revealed that compound 1j significantly inhibited src and mapk signaling and markedly induced apoptosis in tumor tissues. |
2015-08-06 |
2023-08-13 |
mouse |
| Guoxin Mao, Liting Lv, Yifei Liu, Buyou Chen, Mei Li, Tingting Ni, Dunpeng Yang, Hongzhen Zhu, Qun Xue, Runzhou N. The expression levels and prognostic value of high temperature required A2 (HtrA2) in NSCLC. Pathology, research and practice. vol 210. issue 12. 2015-08-05. PMID:25086674. |
in this study we firstly analyzed the apoptosis effect of htra2 in a549 cells by rna interference and cisplatin with western blot and flow cytometry. |
2015-08-05 |
2023-08-13 |
Not clear |
| Tsung-Lin Tsai, An-Chieh Li, Yi-Chieh Chen, Yi-Shun Liao, Thy-Hou Li. Antimicrobial peptide m2163 or m2386 identified from Lactobacillus casei ATCC 334 can trigger apoptosis in the human colorectal cancer cell line SW480. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 5. 2015-08-05. PMID:25557887. |
the real-time quantitative polymerase chain reaction (qpcr) and western blot analyses are subsequently used to study how the apoptosis is induced in the treated sw480 cells by either peptide m2163 or m2386. |
2015-08-05 |
2023-08-13 |
human |
| Wei Li, Guang-Bin Jiang, Jun-Hua Yao, Xiu-Zhen Wang, Ji Wang, Bing-Jie Han, Yang-Yin Xie, Gan-Jian Lin, Hong-Liang Huang, Yun-Jun Li. Ruthenium(II) complexes: DNA-binding, cytotoxicity, apoptosis, cellular localization, cell cycle arrest, reactive oxygen species, mitochondrial membrane potential and western blot analysis. Journal of photochemistry and photobiology. B, Biology. vol 140. 2015-08-04. PMID:25108205. |
ruthenium(ii) complexes: dna-binding, cytotoxicity, apoptosis, cellular localization, cell cycle arrest, reactive oxygen species, mitochondrial membrane potential and western blot analysis. |
2015-08-04 |
2023-08-13 |
Not clear |
| Qun Liu, Rui Sui, Ruirui Li, Jinwei Miao, Jian Li. Biological characteristics of Taxol‑resistant ovarian cancer cells and reversal of Taxol resistance by adenovirus expressing p53. Molecular medicine reports. vol 11. issue 2. 2015-07-30. PMID:25351378. |
to examine the mechanism, the expression of p53 upregulated modulator of apoptosis (puma) was compared between skov3/tax and skov3 cells by western blot analysis. |
2015-07-30 |
2023-08-13 |
Not clear |
| Feng-Qiang Yang, Min Liu, Wei Li, Jian-Ping Che, Guang-Chun Wang, Jun-Hua Zhen. Combination of quercetin and hyperoside inhibits prostate cancer cell growth and metastasis via regulation of microRNA‑21. Molecular medicine reports. vol 11. issue 2. 2015-07-30. PMID:25354548. |
western blot analysis revealed that qh induced apoptosis in human prostate cancer cells via activation of caspase‑3 and cleavage of poly(adenosine diphosphate ribose) polymerase. |
2015-07-30 |
2023-08-13 |
human |
| Hui Wang, Changqing Lu, Qing Li, Jun Xie, Tongbing Chen, Yan Tan, Changping Wu, Jingting Jian. The role of Kif4A in doxorubicin-induced apoptosis in breast cancer cells. Molecules and cells. vol 37. issue 11. 2015-07-28. PMID:25377255. |
using two human breast cancer cell lines mcf-7 (with wild-type p53) and mda-mb-231 (with mutant p53), we quantitated the expression levels of kinesin super-family protein 4a (kif4a) and poly (adp-ribose) polymerase-1 (parp-1) by western blot after doxorubicin treatment and examined the apoptosis by flow cytometry after treatment with doxorubicin and parp-1 inhibitor, 3-aminobenzamide (3-aba). |
2015-07-28 |
2023-08-13 |
human |
| Guang-Bin Jiang, Xiang Zheng, Jun-Hua Yao, Bing-Jie Han, Wei Li, Ji Wang, Hong-Liang Huang, Yun-Jun Li. Ruthenium(II) polypyridyl complexes induce BEL-7402 cell apoptosis by ROS-mediated mitochondrial pathway. Journal of inorganic biochemistry. vol 141. 2015-07-27. PMID:25268891. |
the cellular uptake, apoptosis, comet assay, reactive oxygen species (ros), mitochondrial membrane potential and western blot analysis were investigated. |
2015-07-27 |
2023-08-13 |
Not clear |
| Cunjin Su, Aiming Shi, Guowen Cao, Tao Tao, Ruidong Chen, Zhanhong Hu, Zhu Shen, Hong Tao, Bin Cao, Duanmin Hu, Junjie Ba. Fenofibrate suppressed proliferation and migration of human neuroblastoma cells via oxidative stress dependent of TXNIP upregulation. Biochemical and biophysical research communications. vol 460. issue 4. 2015-07-27. PMID:25839662. |
we used mtt assay to detect cells proliferation, starch wound test to investigate cells migration, h2dcf-da to detect intracellular ros, sirna to interfere txnip and peroxisome proliferator-androgen receptor-alpha (ppar-α) expression, western blot to determine protein levels, flow cytometry to analyze apoptosis. |
2015-07-27 |
2023-08-13 |
human |