| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Triparagiri Ramanivas, Bottu Sushma, V Lakshma Nayak, Kunta Chandra Shekar, Ajay Kumar Srivastav. Design, synthesis and biological evaluations of chirally pure 1,2,3,4-tertrahydroisoquinoline analogs as anti-cancer agents. European journal of medicinal chemistry. vol 92. 2015-11-24. PMID:25615796. |
the apoptosis inducing properties were evaluated by dna fragmentation analysis, caspase-3 activity assay, annexin v-fitc assay and western blot analysis of proapoptotic protein, bax and antiapoptotic protein bcl-2. |
2015-11-24 |
2023-08-13 |
human |
| Jing-Hui Li, Xue Zhang, Yu Meng, Chang-Sheng Li, Hong Ji, Huan-Min Yang, Shi-Ze L. [Cold inducible RNA-binding protein inhibits hippocampal neuronal apoptosis under hypothermia by regulating redox system]. Sheng li xue bao : [Acta physiologica Sinica]. vol 67. issue 4. 2015-11-24. PMID:26300250. |
apoptosis of hippocampal neurons were detected by annexin v-fitc/pi staining and flow cytometry; expression of cirp was determined by western blot; redox-related parameters (t-aoc, gsh-px, sod, mda) were detected by elisa kits. |
2015-11-24 |
2023-08-13 |
rat |
| G G Sun, Y D Wang, Y J Cheng, W N H. The expression of BTG1 is downregulated in nasopharyngeal carcinoma and possibly associated with tumour metastasis. Molecular biology reports. vol 41. issue 9. 2015-11-20. PMID:24985971. |
the expression of proteins involved in cell cycle regulation (cyclin d1), apoptosis (bcl-2) and cell migration (mmp-9) in lebtg1 cells were analyzed by western blot. |
2015-11-20 |
2023-08-13 |
human |
| Yan-Guang Wu, David H Barad, Vitaly A Kushnir, Emanuela Lazzaroni, Qi Wang, David F Albertini, Norbert Gleiche. Aging-related premature luteinization of granulosa cells is avoided by early oocyte retrieval. The Journal of endocrinology. vol 226. issue 3. 2015-11-20. PMID:26264981. |
gene expressions related to gonadotropin activity, steroidogenesis, apoptosis and luteinization were examined by real-time pcr and western blot in gcs collected from follicular fluid. |
2015-11-20 |
2023-08-13 |
human |
| Guang-Zhou An, Hui Xu, Yan Zhou, Le Du, Xia Miao, Da-Peng Jiang, Kang-Chu Li, Guo-Zhen Guo, Chen Zhang, Gui-Rong Din. Effects of long-term 50Hz power-line frequency electromagnetic field on cell behavior in Balb/c 3T3 cells. PloS one. vol 10. issue 2. 2015-11-16. PMID:25695503. |
cell morphology was observed under invert microscope and giemsa staining, cell viability was detected by 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (mtt) assay, cell cycle and apoptosis was examined by flow cytometry, the protein level of proliferating cell nuclear antigen (pcna) and cyclind1 was detected by western blot, cell transformation was examined by soft agar clone assay and plate clone forming test, and cell migration ability was observed by scratch adhesion test. |
2015-11-16 |
2023-08-13 |
human |
| Fengfan Liu, Shaohua Gou, Feihong Chen, Lei Fang, Jian Zha. Study on Antitumor Platinum(II) Complexes of Chiral Diamines with Dicyclic Species as Steric Hindrance. Journal of medicinal chemistry. vol 58. issue 16. 2015-11-16. PMID:26247573. |
western blot analysis demonstrated that 2a could induce a better effect than cisplatin on a mitochondrial-dependent apoptosis pathway. |
2015-11-16 |
2023-08-13 |
Not clear |
| Min Yu, Xingchen Peng, You Lu, Meijuan Huan. [Inhibition Function of Dominant-negative Mutant Gene Survivin-D53A to SPC-A1 Lung Adenocarcinoma Xenograft in Nude Mice Models]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 32. issue 3. 2015-11-14. PMID:26485989. |
in our experiment, spc-a1 cells were transfected in vitro with svv-d53a plasmid and examined for protein expression by western blot, then flow cytometric analysis was used to detect apoptosis. |
2015-11-14 |
2023-08-13 |
mouse |
| Jung Yoon Yang, Min Young Park, Sam Young Park, Hong Il Yoo, Min Seok Kim, Jae Hyung Kim, Won Jae Kim, Ji Yeon Jun. Nitric Oxide-Induced Autophagy in MC3T3-E1 Cells is Associated with Cytoprotection via AMPK Activation. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 19. issue 6. 2015-11-11. PMID:26557017. |
the effect of sodium nitroprusside (snp), an no donor, on the cytotoxicity of the mc3t3-e1 cells was determined by mtt assay and expression of apoptosis or autophagy associated molecules was evaluated by western blot analysis. |
2015-11-11 |
2023-08-13 |
Not clear |
| Yifan Zhang, Bo Yi, Jianhua Ma, Li Zhang, Hongtian Zhang, Yi Yang, Yiwu Da. Quercetin promotes neuronal and behavioral recovery by suppressing inflammatory response and apoptosis in a rat model of intracerebral hemorrhage. Neurochemical research. vol 40. issue 1. 2015-11-10. PMID:25543848. |
the expression levels of il-1β, il-4, il-6 and tnf-α in the brain tissue were assayed by real-time pcr, elisa and western blot, and cell apoptosis was assayed by tunel and caspase-3 staining 3 days after model establishment. |
2015-11-10 |
2023-08-13 |
rat |
| Xiali Zhang, Hongfei Lu, Yibing Wang, Chunju Liu, Weifeng Zhu, Shuangyan Zheng, Fusheng Wa. Taurine induces the apoptosis of breast cancer cells by regulating apoptosis-related proteins of mitochondria. International journal of molecular medicine. vol 35. issue 1. 2015-11-09. PMID:25395275. |
reverse transcription-polymerase chain reaction and western blot analysis were used to detect the levels of mrna and proteins of p53-upregulated modulator of apoptosis (puma), bax and bcl-2. |
2015-11-09 |
2023-08-13 |
mouse |
| Yao Yu, Yu Yang, Jing Wan. Anti-apoptotic and apoptotic pathway analysis of arsenic trioxide‑induced apoptosis in human gastric cancer SGC-7901 cells. Oncology reports. vol 32. issue 3. 2015-11-03. PMID:24969414. |
the protein expression patterns of the apoptosis factors, bax, fas and caspase-8, and anti-apoptosis factors, akt, p-akt, mtor and p-mtor, were evaluated by western blot analysis following treatment of the cells with different as2o3 concentrations in the cell growth media for 48 h. |
2015-11-03 |
2023-08-13 |
human |
| Dandan Tong, Hui Qu, Xiangning Meng, Yang Jiang, Duanyang Liu, Shengqian Ye, He Chen, Yan Jin, Songbin Fu, Jingshu Gen. S-allylmercaptocysteine promotes MAPK inhibitor-induced apoptosis by activating the TGF-β signaling pathway in cancer cells. Oncology reports. vol 32. issue 3. 2015-11-03. PMID:24970681. |
immunohistochemistry and western blot assays showed that samc induced the apoptosis of cancer cells by activating tgf-β1, tβrii, p-smad2/3, smad4 and smad7 signals, and promoting bim expression while decreasing bcl-2 expression and finally activating the mitochondrial apoptosis pathway proteins caspase-3 and caspase-9 in the hepg2 cell line. |
2015-11-03 |
2023-08-13 |
Not clear |
| Seon-Mi Yu, Song-Ja Ki. Withaferin A-caused production of intracellular reactive oxygen species modulates apoptosis via PI3K/Akt and JNKinase in rabbit articular chondrocytes. Journal of Korean medical science. vol 29. issue 8. 2015-10-26. PMID:25120312. |
we also determined that wfa markedly leads to apoptosis as evidenced by accumulation of p53 by western blot analysis. |
2015-10-26 |
2023-08-13 |
rabbit |
| Tian Yang, Asmitananda Thakur, Tianjun Chen, Li Yang, Gao Lei, Yiqian Liang, Shuo Zhang, Hui Ren, Mingwei Che. MicroRNA-15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non-small cell lung cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine. vol 36. issue 6. 2015-10-23. PMID:25874488. |
rna isolation and quantitative real-time pcr (qrt-pcr), western blot analysis, cell proliferation assay, cell cycle analysis, cell apoptosis assay, and migration and invasion assays were done. |
2015-10-23 |
2023-08-13 |
Not clear |
| Gabriella Teti, Giovanna Orsini, Viviana Salvatore, Stefano Focaroli, Maria C Mazzotti, Alessandra Ruggeri, Monica Mattioli-Belmonte, Mirella Falcon. HEMA but not TEGDMA induces autophagy in human gingival fibroblasts. Frontiers in physiology. vol 6. 2015-10-20. PMID:26483703. |
the expression of protein markers for apoptosis (caspase - 3 and parp) and autophagy (beclin - 1 and lc3b i/ii) were analyzed by western blot to investigate the influence of dental resin monomers on mechanisms underlying cell death. |
2015-10-20 |
2023-08-13 |
human |
| Xing-Qi Li, Zhi-Gang Ouyang, Sheng-Hua Zhang, Hong Liu, Yue Shang, Yi Li, Yong-Su Zhe. Synergy of enediyne antibiotic lidamycin and temozolomide in suppressing glioma growth with potentiated apoptosis induction. Journal of neuro-oncology. vol 119. issue 1. 2015-10-19. PMID:24842385. |
as determined by western blot, apoptosis signal pathways in c6 cells and u87 cells were markedly affected by the synergistic alteration of p53, bax, procaspase 3, and bcd-2 expression. |
2015-10-19 |
2023-08-13 |
human |
| Ke-qin Luo, Hui-bao Long, Bing-can X. Reduced apoptosis after acute myocardial infarction by simvastatin. Cell biochemistry and biophysics. vol 71. issue 2. 2015-10-16. PMID:25304741. |
edge myocardial infarction and myocardial cell apoptosis were analyzed using tunel assay, and bcl-2, bax, and caspase-3 protein levels were detected by western blot. |
2015-10-16 |
2023-08-13 |
Not clear |
| Yantao Han, Qixiao Jiang, Hui Gao, Jie Fan, Zhi Wang, Feng Zhong, Yuan Zheng, Zhuoqun Gong, Chunbo Wan. The anti-apoptotic effect of polypeptide from Chlamys farreri (PCF) in UVB-exposed HaCaT cells involves inhibition of iNOS and TGF-β1. Cell biochemistry and biophysics. vol 71. issue 2. 2015-10-16. PMID:25331675. |
apoptosis was confirmed with hoechst 33258 staining; rt-pcr and western blot were used to determine the expression levels of inos and tgf-β1 signaling pathway. |
2015-10-16 |
2023-08-13 |
Not clear |
| Asokan Prema, Udaiyappan Janakiraman, Thamilarasan Manivasagam, Arokiasamy Justin Thenmozh. Neuroprotective effect of lycopene against MPTP induced experimental Parkinson's disease in mice. Neuroscience letters. vol 599. 2015-10-16. PMID:25980996. |
our western blot studies showed that treatment with lycopene reversed mptp induced apoptosis may be due to its antioxidant and antiapoptotic properties. |
2015-10-16 |
2023-08-13 |
mouse |
| Yunhua Wang, Tao Tao, Yinv Dong, Jing Zhang, Zaisheng Qi. Effect of ulinastatin on the expression and distribution of high mobility group box 1 in human colon carcinoma cells in vitro. Molecular medicine reports. vol 11. issue 3. 2015-10-12. PMID:25385285. |
the cell proliferation, invasion, apoptosis and the gene and protein expression of hmgb1 and nf‑κb were detected using a tetrazolium assay, transwell cell invasion assays, a caspase‑3 activity assay, western blot analysis and reverse transcription quantitative polymerase chain reaction, respectively. |
2015-10-12 |
2023-08-13 |
human |