| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Anna Szychlinska, Paola Castrogiovanni, Houda Nsir, Michelino Di Rosa, Claudia Guglielmino, Rosalba Parenti, Giovanna Calabrese, Elisabetta Pricoco, Lucia Salvatorelli, Gaetano Magro, Rosa Imbesi, Ali Mobasheri, Giuseppe Musumec. Engineered cartilage regeneration from adipose tissue derived-mesenchymal stem cells: A morphomolecular study on osteoblast, chondrocyte and apoptosis evaluation. Experimental cell research. vol 357. issue 2. 2017-10-10. PMID:28529106. |
in this study we evaluated the expression of some osteoblasts (runt-related transcription factor 2 (runx2) and osteocalcin), chondrocytes (collagen i, ii and lubricin) and apoptosis (caspase-3) biomarkers in undifferentiated amscs, differentiated amscs in chondrocytes cultured in monolayer and amscs-derived chondrocytes seeded on ccc scaffolds, by different techniques such as immunohistochemistry, elisa, western blot and gene expression analyses. |
2017-10-10 |
2023-08-13 |
rat |
| Na Zhang, Feiming Ye, Wei Zhu, Dexing Hu, Changchen Xiao, Jinliang Nan, Sheng'an Su, Yingchao Wang, Mingfei Liu, Kanglu Gao, Xinyang Hu, Jinghai Chen, Hong Yu, Xiaojie Xie, Jian'an Wan. Cardiac ankyrin repeat protein attenuates cardiomyocyte apoptosis by upregulation of Bcl-2 expression. Biochimica et biophysica acta. vol 1863. issue 12. 2017-10-04. PMID:27713078. |
cardiomyocyte apoptosis induced by exposure to h/r conditions was evaluated by tunel staining and western blot analysis of cleaved caspase-3. |
2017-10-04 |
2023-08-13 |
mouse |
| Zhimei Wang, Haiyan Yu, Shaohua Gou, Feihong Chen, Lei Fan. Design, Synthesis, and Biological Features of Platinum(II) Complexes with Rigid Steric Hindrance. Inorganic chemistry. vol 55. issue 9. 2017-10-03. PMID:27074104. |
moreover, studies including cellular uptake, gel electrophoresis, apoptosis and cell cycle, and western blot analysis have provided insight into the high potency of this compound. |
2017-10-03 |
2023-08-13 |
human |
| Anirban Roy, Manisha Ahir, Saurav Bhattacharya, Pravat Kumar Parida, Arghya Adhikary, Kuladip Jana, Manju Ra. Induction of mitochondrial apoptotic pathway in triple negative breast carcinoma cells by methylglyoxal via generation of reactive oxygen species. Molecular carcinogenesis. vol 56. issue 9. 2017-10-03. PMID:28418078. |
western blot assay was performed to analyze proteins responsible for apoptosis. |
2017-10-03 |
2023-08-13 |
mouse |
| Yun Miao, Jun Xiong, Xuelian Zhang, Huajie Huang, Lixin Yu, Jianfan Chen, Wenfeng Deng, Huiling Xu, Rumin Liu, Chenglin Xiang, Xiangmin Xu, Fu Xion. Genetic diagnosis of polycystic kidney disease, Alport syndrome, and thalassemia minor in a large Chinese family. Clinical science (London, England : 1979). vol 131. issue 19. 2017-09-29. PMID:28827396. |
immunohistochemical, western blot, immunofluorescent, and tdt-mediated dutp nick-end labeling (tunel) analyses were performed to investigate polycystin 1 (pc1) expression, and cell proliferation and apoptosis in kidney tissues from the proband and normal control. |
2017-09-29 |
2023-08-13 |
Not clear |
| Tapas K Nayak, Prabhudutta Mamidi, Abhishek Kumar, Laishram Pradeep K Singh, Subhransu S Sahoo, Soma Chattopadhyay, Subhasis Chattopadhya. Regulation of Viral Replication, Apoptosis and Pro-Inflammatory Responses by 17-AAG during Chikungunya Virus Infection in Macrophages. Viruses. vol 9. issue 1. 2017-09-26. PMID:28067803. |
moreover, host immune modulation and apoptosis were studied through flow cytometry, western blot and elisa. |
2017-09-26 |
2023-08-13 |
mouse |
| Wei Qiang, Fang Sui, Jingjing Ma, Xinru Li, Xiaojuan Ren, Yuan Shao, Jiazhe Liu, Haixia Guan, Bingyin Shi, Peng Ho. Proteasome inhibitor MG132 induces thyroid cancer cell apoptosis by modulating the activity of transcription factor FOXO3a. Endocrine. vol 56. issue 1. 2017-09-26. PMID:28220348. |
using flow cytometry, western blot, immunofluorescence staining and quantitative rt-pcr assays, we assessed proteasome inhibitor mg132-induced apoptosis in thyroid cancer cells and its effect on the expression and activity of forkhead box o3. |
2017-09-26 |
2023-08-13 |
Not clear |
| Haosen Zhao, Shurui Chen, Kai Gao, Zipeng Zhou, Chen Wang, Zhaoliang Shen, Yue Guo, Zhuo Li, Zhanghui Wan, Chang Liu, Xifan Me. Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway. Neuroscience. vol 348. 2017-09-26. PMID:28238848. |
spinal cord tissue was assessed by western blot, reverse transcription-polymerase chain reaction (rt-pcr) and immunohistochemical analyses 7days after injury for changes in expression of sirt1/ampk signaling pathway, autophagy and apoptosis proteins. |
2017-09-26 |
2023-08-13 |
rat |
| Q D Mao, W Zhang, K Zhao, B Cao, H Yuan, L Z Wei, M Q Song, X S Li. MicroRNA-455 suppresses the oncogenic function of HDAC2 in human colorectal cancer. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 50. issue 6. 2017-09-25. PMID:28538837. |
finally, cells were transfected, respectively, with mir-455 mimics or mir-455 negative control (mir-nc) and the expression of hdac2, cell proliferation and apoptosis of transfected cells were respectively evaluated by western blot analysis, mtt assay and flow cytometry. |
2017-09-25 |
2023-08-13 |
human |
| Xinghua Qin, Xiaoliang Li, Chuanming Liu, Ziwei Che. A novel mechanism of pre-transplant insulin resistance contributing to post-transplant complications: Cyclosporin A-induced O-GlcNAcylation. Biochemical and biophysical research communications. vol 492. issue 2. 2017-09-25. PMID:28830815. |
western blot and flow cytometric analysis showed that csa induced apoptosis in insulin-resistant c2c12 cells. |
2017-09-25 |
2023-08-13 |
Not clear |
| Somayeh Athari Nik Azm, Mohammadreza Vafa, Mohammad Sharifzadeh, Majid Safa, Anis Barati, Abbas Mirshafie. Effects of M2000 (D-Mannuronic Acid) on Learning, Memory Retrieval, and Associated Determinants in a Rat Model of Alzheimer's Disease. American journal of Alzheimer's disease and other dementias. vol 32. issue 1. 2017-09-22. PMID:28100077. |
in this work, the effect of m2000 on the treatment of alzheimer's disease (ad) was performed by morris water maze experiment, and the immunological assessments were carried out by western blot, apoptosis (procaspase-3, bax/bcl |
2017-09-22 |
2023-08-13 |
rat |
| Hongqian Cao, Chunyan Li, Wen Qi, Xiangjun Meng, Rui Tian, Yanfei Qi, Wei Yang, Juan L. Synthesis, cytotoxicity and antitumour mechanism investigations of polyoxometalate doped silica nanospheres on breast cancer MCF-7 cells. PloS one. vol 12. issue 7. 2017-09-22. PMID:28704559. |
flow cytometric analysis showed nanoparticles induced the apoptosis by arresting the cells in s phase and western blot analysis indicated they promoted apoptosis by inhibiting the bcl-2 protein. |
2017-09-22 |
2023-08-13 |
human |
| Xiaolei Li, Hui Chen, Shuguang Wang, Jihang Dai, Lianqi Yan, Jingcheng Wang, Yu Su. Tacrolimus induces fibroblasts apoptosis and reduces epidural fibrosis by regulating miR-429 and its target of RhoE. Biochemical and biophysical research communications. vol 490. issue 4. 2017-09-21. PMID:28669722. |
flow cytometry and western blot analysis were used to determine the effects of fk506 and mir-429 on fibroblast apoptosis. |
2017-09-21 |
2023-08-13 |
rat |
| Jian Dong, Yuanhang Zhou, Zhiwei Liao, Qi Huang, Shidong Feng, Yue L. Role of γ-glutamyl cyclotransferase as a therapeutic target for colorectal cancer based on the lentivirus-mediated system. Anti-cancer drugs. vol 27. issue 10. 2017-09-20. PMID:27500968. |
further, western blot and pathscan intracellular signaling were used to detect intracellular signaling associated with cell growth and apoptosis induced by ggct knockdown. |
2017-09-20 |
2023-08-13 |
human |
| Tuo Zhao, Xin Tang, Channakeshava Sokke Umeshappa, Hong Ma, Haijun Gao, Yulin Deng, Andrew Freywald, Jim Xian. Simulated Microgravity Promotes Cell Apoptosis Through Suppressing Uev1A/TICAM/TRAF/NF-κB-Regulated Anti-Apoptosis and p53/PCNA- and ATM/ATR-Chk1/2-Controlled DNA-Damage Response Pathways. Journal of cellular biochemistry. vol 117. issue 9. 2017-09-19. PMID:26887372. |
western blot analysis also indicates that smg causes inhibition of an apoptosis suppressor, pnf-κb-p65, which is complemented by the predominant localization of nf-κb-p65 in the cytoplasm. |
2017-09-19 |
2023-08-13 |
human |
| Zheng Ni, Liang Tao, Xu Xiaohui, Zhao Zelin, Liu Jiangang, Song Zhao, Huo Weikang, Xu Hongchao, Wang Qiujing, Li Xi. Polydatin impairs mitochondria fitness and ameliorates podocyte injury by suppressing Drp1 expression. Journal of cellular physiology. vol 232. issue 10. 2017-09-19. PMID:28383775. |
we use western blot analysis to demonstrate that pd reversed podocyte apoptosis induced by hg via suppressing dynamin-related protein 1 (drp1). |
2017-09-19 |
2023-08-13 |
mouse |
| Long Jiang, Ruijuan Yin, Xueting Wang, Jiajia Dai, Jing Li, Tao Jiang, Rilei Y. Design and synthesis of neolamellarin a derivatives targeting heat shock protein 90. European journal of medicinal chemistry. vol 135. 2017-09-19. PMID:28426997. |
western blot analysis demonstrated that these compounds induced dramatic depletion of the examined client proteins of hsp90, and accelerated cancer cell apoptosis. |
2017-09-19 |
2023-08-13 |
Not clear |
| Sijia Chen, Jialong Tao, Fengyun Zhong, Yang Jiao, Jiaying Xu, Qiang Shen, Haichao Wang, Saijun Fan, Yusong Zhan. Polydatin down-regulates the phosphorylation level of Creb and induces apoptosis in human breast cancer cell. PloS one. vol 12. issue 5. 2017-09-18. PMID:28467448. |
the expression of several proteins associated with cell cycle and apoptosis were analyzed by western blot analysis. |
2017-09-18 |
2023-08-13 |
human |
| Sara F Ferreiro, Natalia Vilariño, Cristina Carrera, M Carmen Louzao, Germán Santamarina, Antonio G Cantalapiedra, J Manuel Cifuentes, Andrés Crespo, Luis M Botan. In vivo cardiomyocyte response to YTX- and AZA-1-induced damage: autophagy versus apoptosis. Archives of toxicology. vol 91. issue 4. 2017-09-11. PMID:27709272. |
because autophagy and apoptosis are often found in dying cardiomyocytes, several autophagic and apoptotic markers were determined by western blot in heart tissues of these rats. |
2017-09-11 |
2023-08-13 |
human |
| Y D Huang, X Tong, Q Chen, S W Xia, Y Zhuo, Z H Kang, X Y Xu. Mechanism of pingyangmycin-induced apoptosis of cultured human umbilical vein endothelial cells. Genetics and molecular research : GMR. vol 16. issue 2. 2017-09-11. PMID:28510249. |
annexin v-fitc/propidium iodide stain was used to detect apoptosis, and western blot was used to detect the expression of glucose-related protein 78 (gpr78) and c/ebp homologous protein (chop) endoplasmic reticulum stress proteins. |
2017-09-11 |
2023-08-13 |
human |